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Volumn 92, Issue 8, 2013, Pages 1079-1090

Monitoring dendritic cell and cytokine biomarkers during remission prior to relapse in patients with FLT3-ITD acute myeloid leukemia

Author keywords

Dendritic cell; Immune monitoring; Inflammatory cytokines; Leukemia; Myeloid derived suppressor cells; Risk of relapse

Indexed keywords

CD123 ANTIGEN; CD135 ANTIGEN; CD14 ANTIGEN; CD19 ANTIGEN; CD20 ANTIGEN; CYTOKINE; GLYCOPROTEIN P 15095; HLA DR ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; NUCLEOPHOSMIN; TUMOR NECROSIS FACTOR ALPHA; WT1 PROTEIN;

EID: 84880283502     PISSN: 09395555     EISSN: 14320584     Source Type: Journal    
DOI: 10.1007/s00277-013-1744-y     Document Type: Article
Times cited : (27)

References (46)
  • 1
    • 84055218304 scopus 로고    scopus 로고
    • Acute myeloid leukemia: 2012 update on diagnosis, risk stratification, and management
    • 10.1002/ajh.22246 22180162 10.1002/ajh.22246
    • Estey EH (2012) Acute myeloid leukemia: 2012 update on diagnosis, risk stratification, and management. Am J Hematol 87(1):89-99. doi: 10.1002/ajh.22246
    • (2012) Am J Hematol , vol.87 , Issue.1 , pp. 89-99
    • Estey, E.H.1
  • 3
    • 33947220301 scopus 로고    scopus 로고
    • FLT3/ITD expression increases expansion, survival and entry into cell cycle of human haematopoietic stem/progenitor cells
    • 10.1111/j.1365-2141.2007.06525.x 17359372 1:CAS:528:DC%2BD2sXlt1Oit74%3D
    • Li L, Piloto O, Kim KT, Ye Z, Nguyen HB, Yu X, Levis M, Cheng L, Small D (2007) FLT3/ITD expression increases expansion, survival and entry into cell cycle of human haematopoietic stem/progenitor cells. Br J Haematol 137(1):64-75. doi: 10.1111/j.1365-2141.2007.06525.x
    • (2007) Br J Haematol , vol.137 , Issue.1 , pp. 64-75
    • Li, L.1    Piloto, O.2    Kim, K.T.3    Ye, Z.4    Nguyen, H.B.5    Yu, X.6    Levis, M.7    Cheng, L.8    Small, D.9
  • 4
    • 41949090673 scopus 로고    scopus 로고
    • The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia
    • 10.1182/blood-2007-08-109090 17957027 10.1182/blood-2007-08-109090 1:CAS:528:DC%2BD1cXivFaktbY%3D
    • Gale RE, Green C, Allen C, Mead AJ, Burnett AK, Hills RK, Linch DC (2008) The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia. Blood 111(5):2776-2784. doi: 10.1182/blood-2007-08- 109090
    • (2008) Blood , vol.111 , Issue.5 , pp. 2776-2784
    • Gale, R.E.1    Green, C.2    Allen, C.3    Mead, A.J.4    Burnett, A.K.5    Hills, R.K.6    Linch, D.C.7
  • 6
    • 33845263501 scopus 로고    scopus 로고
    • High meningioma 1 (MN1) expression as a predictor for poor outcome in acute myeloid leukemia with normal cytogenetics
    • 10.1182/blood-2006-04-014845 16912223 10.1182/blood-2006-04-014845 1:CAS:528:DC%2BD28Xht1Kgs7rM
    • Heuser M, Beutel G, Krauter J, Dohner K, von Neuhoff N, Schlegelberger B, Ganser A (2006) High meningioma 1 (MN1) expression as a predictor for poor outcome in acute myeloid leukemia with normal cytogenetics. Blood 108(12):3898-3905. doi: 10.1182/blood-2006-04-014845
    • (2006) Blood , vol.108 , Issue.12 , pp. 3898-3905
    • Heuser, M.1    Beutel, G.2    Krauter, J.3    Dohner, K.4    Von Neuhoff, N.5    Schlegelberger, B.6    Ganser, A.7
  • 7
    • 79952092487 scopus 로고    scopus 로고
    • Molecular genetics of adult acute myeloid leukemia: Prognostic and therapeutic implications
    • 10.1200/JCO.2010.30.2554 21220609 10.1200/JCO.2010.30.2554 1:CAS:528:DC%2BC3MXjtFCjtro%3D
    • Marcucci G, Haferlach T, Dohner H (2011) Molecular genetics of adult acute myeloid leukemia: prognostic and therapeutic implications. J Clin Oncol 29(5):475-486. doi: 10.1200/JCO.2010.30.2554
    • (2011) J Clin Oncol , vol.29 , Issue.5 , pp. 475-486
    • Marcucci, G.1    Haferlach, T.2    Dohner, H.3
  • 9
    • 84857622836 scopus 로고    scopus 로고
    • Impact of FLT3 internal tandem duplication on the outcome of related and unrelated hematopoietic transplantation for adult acute myeloid leukemia in first remission: A retrospective analysis
    • 10.1200/JCO.2011.36.9868 22291086 10.1200/JCO.2011.36.9868
    • Brunet S, Labopin M, Esteve J, Cornelissen J, Socie G, Iori AP, Verdonck LF, Volin L, Gratwohl A, Sierra J, Mohty M, Rocha V (2012) Impact of FLT3 internal tandem duplication on the outcome of related and unrelated hematopoietic transplantation for adult acute myeloid leukemia in first remission: a retrospective analysis. J Clin Oncol 30(7):735-741. doi: 10.1200/JCO.2011.36.9868
    • (2012) J Clin Oncol , vol.30 , Issue.7 , pp. 735-741
    • Brunet, S.1    Labopin, M.2    Esteve, J.3    Cornelissen, J.4    Socie, G.5    Iori, A.P.6    Verdonck, L.F.7    Volin, L.8    Gratwohl, A.9    Sierra, J.10    Mohty, M.11    Rocha, V.12
  • 10
    • 84859572115 scopus 로고    scopus 로고
    • Risk stratification-directed donor lymphocyte infusion could reduce relapse of standard-risk acute leukemia patients after allogeneic hematopoietic stem cell transplantation
    • 10.1182/blood-2011-09-380386 22337715 10.1182/blood-2011-09-380386 1:CAS:528:DC%2BC38Xlslyjsrs%3D
    • Yan CH, Liu DH, Liu KY, Xu LP, Liu YR, Chen H, Han W, Wang Y, Qin YZ, Huang XJ (2012) Risk stratification-directed donor lymphocyte infusion could reduce relapse of standard-risk acute leukemia patients after allogeneic hematopoietic stem cell transplantation. Blood 119(14):3256-3262. doi: 10.1182/blood-2011-09-380386
    • (2012) Blood , vol.119 , Issue.14 , pp. 3256-3262
    • Yan, C.H.1    Liu, D.H.2    Liu, K.Y.3    Xu, L.P.4    Liu, Y.R.5    Chen, H.6    Han, W.7    Wang, Y.8    Qin, Y.Z.9    Huang, X.J.10
  • 11
    • 0032546352 scopus 로고    scopus 로고
    • Dendritic cells and the control of immunity
    • 10.1038/32588 9521319 10.1038/32588 1:CAS:528:DyaK1cXitFWrsr8%3D
    • Banchereau J, Steinman RM (1998) Dendritic cells and the control of immunity. Nature 392(6673):245-252. doi: 10.1038/32588
    • (1998) Nature , vol.392 , Issue.6673 , pp. 245-252
    • Banchereau, J.1    Steinman, R.M.2
  • 12
    • 84858780815 scopus 로고    scopus 로고
    • Cancer immunotherapy via dendritic cells
    • 10.1038/nrc3258 22437871 10.1038/nrc3258 1:CAS:528:DC%2BC38XksVehtrY%3D
    • Palucka K, Banchereau J (2012) Cancer immunotherapy via dendritic cells. Nat Rev Cancer 12(4):265-277. doi: 10.1038/nrc3258
    • (2012) Nat Rev Cancer , vol.12 , Issue.4 , pp. 265-277
    • Palucka, K.1    Banchereau, J.2
  • 14
    • 80052365794 scopus 로고    scopus 로고
    • Elevated frequencies of leukemic myeloid and plasmacytoid dendritic cells in acute myeloid leukemia with the FLT3 internal tandem duplication
    • 10.1007/s00277-011-1231-2 21520003
    • Rickmann M, Krauter J, Stamer K, Heuser M, Salguero G, Mischak-Weissinger E, Ganser A, Stripecke R (2011) Elevated frequencies of leukemic myeloid and plasmacytoid dendritic cells in acute myeloid leukemia with the FLT3 internal tandem duplication. Ann Hematol. doi: 10.1007/s00277-011-1231-2
    • (2011) Ann Hematol
    • Rickmann, M.1    Krauter, J.2    Stamer, K.3    Heuser, M.4    Salguero, G.5    Mischak-Weissinger, E.6    Ganser, A.7    Stripecke, R.8
  • 15
    • 0033231334 scopus 로고    scopus 로고
    • Stress hormones, Th1/Th2 patterns, pro/anti-inflammatory cytokines and susceptibility to disease
    • 10.1016/S1043-2760(99)00188-5 1:CAS:528:DyaK1MXmvVGru78%3D
    • Elenkov IJ, Chrousos GP (1999) Stress hormones, Th1/Th2 patterns, pro/anti-inflammatory cytokines and susceptibility to disease. Trends Endocrinol Metab TEM 10(9):359-368
    • (1999) Trends Endocrinol Metab TEM , vol.10 , Issue.9 , pp. 359-368
    • Elenkov, I.J.1    Chrousos, G.P.2
  • 16
    • 0036307544 scopus 로고    scopus 로고
    • Stress hormones, proinflammatory and antiinflammatory cytokines, and autoimmunity
    • 12114286 10.1111/j.1749-6632.2002.tb04229.x 1:CAS:528: DC%2BD38XlvVWmur0%3D
    • Elenkov IJ, Chrousos GP (2002) Stress hormones, proinflammatory and antiinflammatory cytokines, and autoimmunity. Ann N Y Acad Sci 966:290-303
    • (2002) Ann N y Acad Sci , vol.966 , pp. 290-303
    • Elenkov, I.J.1    Chrousos, G.P.2
  • 17
    • 84856541896 scopus 로고    scopus 로고
    • Interleukin 10 in the tumor microenvironment: A target for anticancer immunotherapy
    • 10.1007/s12026-011-8262-6 22139852 10.1007/s12026-011-8262-6 1:CAS:528:DC%2BC3MXhs1OisbjK
    • Sato T, Terai M, Tamura Y, Alexeev V, Mastrangelo MJ, Selvan SR (2011) Interleukin 10 in the tumor microenvironment: a target for anticancer immunotherapy. Immunol Res 51(2-3):170-182. doi: 10.1007/s12026-011-8262-6
    • (2011) Immunol Res , vol.51 , Issue.2-3 , pp. 170-182
    • Sato, T.1    Terai, M.2    Tamura, Y.3    Alexeev, V.4    Mastrangelo, M.J.5    Selvan, S.R.6
  • 18
    • 34547410247 scopus 로고    scopus 로고
    • Consensus paper of the WFSBP Task Force on Biological Markers: Biological markers in depression
    • 10.1080/15622970701263303 17654407 10.1080/15622970701263303
    • Mossner R, Mikova O, Koutsilieri E, Saoud M, Ehlis AC, Muller N, Fallgatter AJ, Riederer P (2007) Consensus paper of the WFSBP Task Force on Biological Markers: biological markers in depression. World J Biol Psychiatry 8(3):141-174. doi: 10.1080/15622970701263303
    • (2007) World J Biol Psychiatry , vol.8 , Issue.3 , pp. 141-174
    • Mossner, R.1    Mikova, O.2    Koutsilieri, E.3    Saoud, M.4    Ehlis, A.C.5    Muller, N.6    Fallgatter, A.J.7    Riederer, P.8
  • 19
    • 84863601838 scopus 로고    scopus 로고
    • Chronic inflammation in cancer development
    • 10.3389/fimmu.2011.00098 22566887
    • Multhoff G, Molls M, Radons J (2011) Chronic inflammation in cancer development. Front Immunol 2:98. doi: 10.3389/fimmu.2011.00098
    • (2011) Front Immunol , vol.2 , pp. 98
    • Multhoff, G.1    Molls, M.2    Radons, J.3
  • 20
    • 84863292982 scopus 로고    scopus 로고
    • Aberrant expression of Treg-associated cytokine IL-35 along with IL-10 and TGF-beta in acute myeloid leukemia
    • 10.3892/ol.2012.614 22783403 1:CAS:528:DC%2BC38Xntlyhu70%3D
    • Wu H, Li P, Shao N, Ma J, Ji M, Sun X, Ma D, Ji C (2012) Aberrant expression of Treg-associated cytokine IL-35 along with IL-10 and TGF-beta in acute myeloid leukemia. Oncol Lett 3(5):1119-1123. doi: 10.3892/ol.2012.614
    • (2012) Oncol Lett , vol.3 , Issue.5 , pp. 1119-1123
    • Wu, H.1    Li, P.2    Shao, N.3    Ma, J.4    Ji, M.5    Sun, X.6    Ma, D.7    Ji, C.8
  • 21
    • 0037114829 scopus 로고    scopus 로고
    • Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics: A study of the AML Study Group Ulm
    • 10.1182/blood-2002-05-1440 12393388 10.1182/blood-2002-05-1440 1:CAS:528:DC%2BD38XpsFCqsL4%3D
    • Frohling S, Schlenk RF, Breitruck J, Benner A, Kreitmeier S, Tobis K, Dohner H, Dohner K (2002) Prognostic significance of activating FLT3 mutations in younger adults (16 to 60 years) with acute myeloid leukemia and normal cytogenetics: a study of the AML Study Group Ulm. Blood 100(13):4372-4380. doi: 10.1182/blood-2002-05-1440
    • (2002) Blood , vol.100 , Issue.13 , pp. 4372-4380
    • Frohling, S.1    Schlenk, R.F.2    Breitruck, J.3    Benner, A.4    Kreitmeier, S.5    Tobis, K.6    Dohner, H.7    Dohner, K.8
  • 22
    • 23844458023 scopus 로고    scopus 로고
    • Prognostic impact of RT-PCR-based quantification of WT1 gene expression during MRD monitoring of acute myeloid leukemia
    • 10.1038/sj.leu.2403809 15920493 10.1038/sj.leu.2403809 1:CAS:528:DC%2BD2MXmtlSjsr8%3D
    • Weisser M, Kern W, Rauhut S, Schoch C, Hiddemann W, Haferlach T, Schnittger S (2005) Prognostic impact of RT-PCR-based quantification of WT1 gene expression during MRD monitoring of acute myeloid leukemia. Leukemia 19(8):1416-1423. doi: 10.1038/sj.leu.2403809
    • (2005) Leukemia , vol.19 , Issue.8 , pp. 1416-1423
    • Weisser, M.1    Kern, W.2    Rauhut, S.3    Schoch, C.4    Hiddemann, W.5    Haferlach, T.6    Schnittger, S.7
  • 23
    • 55149094739 scopus 로고    scopus 로고
    • Interleukin-10: New perspectives on an old cytokine
    • 10.1111/j.1600-065X.2008.00706.x 19161426 10.1111/j.1600-065X.2008.00706. x 1:CAS:528:DC%2BD1MXhsFGls7%2FP
    • Mosser DM, Zhang X (2008) Interleukin-10: new perspectives on an old cytokine. Immunol Rev 226:205-218. doi: 10.1111/j.1600-065X.2008.00706.x
    • (2008) Immunol Rev , vol.226 , pp. 205-218
    • Mosser, D.M.1    Zhang, X.2
  • 24
    • 0036308243 scopus 로고    scopus 로고
    • Cytokines, acute-phase proteins, and hormones: IL-1 and TNF-alpha production in contact-mediated activation of monocytes by T lymphocytes
    • 12114305 10.1111/j.1749-6632.2002.tb04248.x 1:CAS:528: DC%2BD38XlvVWls7w%3D
    • Burger D, Dayer JM (2002) Cytokines, acute-phase proteins, and hormones: IL-1 and TNF-alpha production in contact-mediated activation of monocytes by T lymphocytes. Ann N Y Acad Sci 966:464-473
    • (2002) Ann N y Acad Sci , vol.966 , pp. 464-473
    • Burger, D.1    Dayer, J.M.2
  • 26
    • 10744219997 scopus 로고    scopus 로고
    • Dendritic cell recovery after allogeneic stem-cell transplantation in acute leukemia: Correlations with clinical and transplant characteristics
    • 10.1046/j.0902-4441.2004.00172.x 14962258 10.1046/j.0902-4441.2004.00172. x
    • Porta MD, Rigolin GM, Alessandrino EP, Maiocchi M, Malcovati L, Vanelli L, Barate C, Rumi E, Ciccone M, Cuneo A, Lazzarino M, Castoldi G (2004) Dendritic cell recovery after allogeneic stem-cell transplantation in acute leukemia: correlations with clinical and transplant characteristics. Eur J Haematol 72(1):18-25. doi: 10.1046/j.0902-4441.2004.00172.x
    • (2004) Eur J Haematol , vol.72 , Issue.1 , pp. 18-25
    • Porta, M.D.1    Rigolin, G.M.2    Alessandrino, E.P.3    Maiocchi, M.4    Malcovati, L.5    Vanelli, L.6    Barate, C.7    Rumi, E.8    Ciccone, M.9    Cuneo, A.10    Lazzarino, M.11    Castoldi, G.12
  • 27
    • 78650756969 scopus 로고    scopus 로고
    • Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function
    • 10.1016/j.it.2010.10.002 21067974 10.1016/j.it.2010.10.002 1:CAS:528:DC%2BC3MXkt1CmsA%3D%3D
    • Condamine T, Gabrilovich DI (2011) Molecular mechanisms regulating myeloid-derived suppressor cell differentiation and function. Trends Immunol 32(1):19-25. doi: 10.1016/j.it.2010.10.002
    • (2011) Trends Immunol , vol.32 , Issue.1 , pp. 19-25
    • Condamine, T.1    Gabrilovich, D.I.2
  • 28
    • 77950829023 scopus 로고    scopus 로고
    • Mechanism of T cell tolerance induced by myeloid-derived suppressor cells
    • 10.4049/jimmunol.0902661 20142361 10.4049/jimmunol.0902661 1:CAS:528:DC%2BC3cXis1yitrs%3D
    • Nagaraj S, Schrum AG, Cho HI, Celis E, Gabrilovich DI (2010) Mechanism of T cell tolerance induced by myeloid-derived suppressor cells. J Immunol 184(6):3106-3116. doi: 10.4049/jimmunol.0902661
    • (2010) J Immunol , vol.184 , Issue.6 , pp. 3106-3116
    • Nagaraj, S.1    Schrum, A.G.2    Cho, H.I.3    Celis, E.4    Gabrilovich, D.I.5
  • 29
    • 53349099219 scopus 로고    scopus 로고
    • Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein
    • 10.1084/jem.20080132 18809714 10.1084/jem.20080132 1:CAS:528: DC%2BD1cXht1SrtLvE
    • Cheng P, Corzo CA, Luetteke N, Yu B, Nagaraj S, Bui MM, Ortiz M, Nacken W, Sorg C, Vogl T, Roth J, Gabrilovich DI (2008) Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein. J Exp Med 205(10):2235-2249. doi: 10.1084/jem.20080132
    • (2008) J Exp Med , vol.205 , Issue.10 , pp. 2235-2249
    • Cheng, P.1    Corzo, C.A.2    Luetteke, N.3    Yu, B.4    Nagaraj, S.5    Bui, M.M.6    Ortiz, M.7    Nacken, W.8    Sorg, C.9    Vogl, T.10    Roth, J.11    Gabrilovich, D.I.12
  • 30
    • 77958036074 scopus 로고    scopus 로고
    • Leukemic cell products down-regulate human dendritic cell differentiation
    • 10.1007/s00262-010-0890-5 20607236 10.1007/s00262-010-0890-5 1:CAS:528:DC%2BC3cXhtVyrtrvN
    • Motta JM, Nascimento CR, Rumjanek VM (2010) Leukemic cell products down-regulate human dendritic cell differentiation. Cancer Immunol Immunother 59(11):1645-1653. doi: 10.1007/s00262-010-0890-5
    • (2010) Cancer Immunol Immunother , vol.59 , Issue.11 , pp. 1645-1653
    • Motta, J.M.1    Nascimento, C.R.2    Rumjanek, V.M.3
  • 31
    • 0035164478 scopus 로고    scopus 로고
    • Increased production of immature myeloid cells in cancer patients: A mechanism of immunosuppression in cancer
    • 11123353 1:CAS:528:DC%2BD3MXis1elsw%3D%3D
    • Almand B, Clark JI, Nikitina E, van Beynen J, English NR, Knight SC, Carbone DP, Gabrilovich DI (2001) Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer. J Immunol 166(1):678-689
    • (2001) J Immunol , vol.166 , Issue.1 , pp. 678-689
    • Almand, B.1    Clark, J.I.2    Nikitina, E.3    Van Beynen, J.4    English, N.R.5    Knight, S.C.6    Carbone, D.P.7    Gabrilovich, D.I.8
  • 32
    • 29144508613 scopus 로고    scopus 로고
    • Dendritic cell dysfunction in cancer: A mechanism for immunosuppression
    • 10.1111/j.1440-1711.2005.01371.x 16174093 10.1111/j.1440-1711.2005.01371. x 1:CAS:528:DC%2BD2MXhtFeqtrnI
    • Pinzon-Charry A, Maxwell T, Lopez JA (2005) Dendritic cell dysfunction in cancer: a mechanism for immunosuppression. Immunol Cell Biol 83(5):451-461. doi: 10.1111/j.1440-1711.2005.01371.x
    • (2005) Immunol Cell Biol , vol.83 , Issue.5 , pp. 451-461
    • Pinzon-Charry, A.1    Maxwell, T.2    Lopez, J.A.3
  • 33
    • 77950690023 scopus 로고    scopus 로고
    • Interleukin-6 in bone metastasis and cancer progression
    • 10.1016/j.ejca.2010.02.026 20335016 10.1016/j.ejca.2010.02.026 1:CAS:528:DC%2BC3cXkvFKqtrs%3D
    • Ara T, Declerck YA (2010) Interleukin-6 in bone metastasis and cancer progression. Eur J Cancer 46(7):1223-1231. doi: 10.1016/j.ejca.2010.02.026
    • (2010) Eur J Cancer , vol.46 , Issue.7 , pp. 1223-1231
    • Ara, T.1    Declerck, Y.A.2
  • 34
    • 30344453908 scopus 로고    scopus 로고
    • Cytokines in the differentiation therapy of leukemia: From laboratory investigations to clinical applications
    • 10.1080/10408360500295154 16390682 10.1080/10408360500295154 1:CAS:528:DC%2BD2MXhtlGhsbbP
    • Leung KN, Mak NK, Fung MC (2005) Cytokines in the differentiation therapy of leukemia: from laboratory investigations to clinical applications. Crit Rev Clin Lab Sci 42(5-6):473-514. doi: 10.1080/10408360500295154
    • (2005) Crit Rev Clin Lab Sci , vol.42 , Issue.5-6 , pp. 473-514
    • Leung, K.N.1    Mak, N.K.2    Fung, M.C.3
  • 35
    • 33744719480 scopus 로고    scopus 로고
    • Inhibition of IL-1, IL-6, and TNF-alpha in immune-mediated inflammatory diseases
    • 10.1007/s00281-006-0012-9 16738952 10.1007/s00281-006-0012-9
    • Moller B, Villiger PM (2006) Inhibition of IL-1, IL-6, and TNF-alpha in immune-mediated inflammatory diseases. Springer Semin Immunopathol 27(4):391-408. doi: 10.1007/s00281-006-0012-9
    • (2006) Springer Semin Immunopathol , vol.27 , Issue.4 , pp. 391-408
    • Moller, B.1    Villiger, P.M.2
  • 36
    • 84875221247 scopus 로고    scopus 로고
    • Radiation, inflammation, and immune responses in cancer
    • 10.3389/fonc.2012.00058 22675673
    • Multhoff G, Radons J (2012) Radiation, inflammation, and immune responses in cancer. Front Oncol 2:58. doi: 10.3389/fonc.2012.00058
    • (2012) Front Oncol , vol.2 , pp. 58
    • Multhoff, G.1    Radons, J.2
  • 38
    • 61349100687 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells as regulators of the immune system
    • 10.1038/nri2506 19197294 10.1038/nri2506 1:CAS:528:DC%2BD1MXhsFeqsbw%3D
    • Gabrilovich DI, Nagaraj S (2009) Myeloid-derived suppressor cells as regulators of the immune system. Nat Rev Immunol 9(3):162-174. doi: 10.1038/nri2506
    • (2009) Nat Rev Immunol , vol.9 , Issue.3 , pp. 162-174
    • Gabrilovich, D.I.1    Nagaraj, S.2
  • 39
    • 84856706929 scopus 로고    scopus 로고
    • Phenotype, function and clinical implications of myeloid-derived suppressor cells in cancer patients
    • 10.1007/s00262-011-1161-9 22120756 10.1007/s00262-011-1161-9 1:CAS:528:DC%2BC38XhsVWmuro%3D
    • Filipazzi P, Huber V, Rivoltini L (2012) Phenotype, function and clinical implications of myeloid-derived suppressor cells in cancer patients. Cancer Immunol Immunother 61(2):255-263. doi: 10.1007/s00262-011-1161-9
    • (2012) Cancer Immunol Immunother , vol.61 , Issue.2 , pp. 255-263
    • Filipazzi, P.1    Huber, V.2    Rivoltini, L.3
  • 40
    • 35448954376 scopus 로고    scopus 로고
    • Reduced inflammation in the tumor microenvironment delays the accumulation of myeloid-derived suppressor cells and limits tumor progression
    • 10.1158/0008-5472.CAN-07-2354 17942936 10.1158/0008-5472.CAN-07-2354 1:CAS:528:DC%2BD2sXhtFOnsLrF
    • Bunt SK, Yang L, Sinha P, Clements VK, Leips J, Ostrand-Rosenberg S (2007) Reduced inflammation in the tumor microenvironment delays the accumulation of myeloid-derived suppressor cells and limits tumor progression. Cancer Res 67(20):10019-10026. doi: 10.1158/0008-5472.CAN-07-2354
    • (2007) Cancer Res , vol.67 , Issue.20 , pp. 10019-10026
    • Bunt, S.K.1    Yang, L.2    Sinha, P.3    Clements, V.K.4    Leips, J.5    Ostrand-Rosenberg, S.6
  • 41
    • 84873569840 scopus 로고    scopus 로고
    • Immunosuppressive CD14(+)HLA-DR(low/neg) IDO(+) myeloid cells in patients following allogeneic hematopoietic stem cell transplantation
    • 10.1038/leu.2012.215 22828446
    • Mougiakakos D, Jitschin R, von Bahr L, Poschke I, Gary R, Sundberg B, Gerbitz A, Ljungman P, Le Blanc K (2012) Immunosuppressive CD14(+)HLA-DR(low/ neg) IDO(+) myeloid cells in patients following allogeneic hematopoietic stem cell transplantation. Leukemia. doi: 10.1038/leu.2012.215
    • (2012) Leukemia
    • Mougiakakos, D.1    Jitschin, R.2    Von Bahr, L.3    Poschke, I.4    Gary, R.5    Sundberg, B.6    Gerbitz, A.7    Ljungman, P.8    Le Blanc, K.9
  • 42
    • 42449145174 scopus 로고    scopus 로고
    • Internal tandem duplication of FLT3 (FLT3/ITD) induces increased ROS production, DNA damage, and misrepair: Implications for poor prognosis in AML
    • 10.1182/blood-2007-05-092510 18192505 10.1182/blood-2007-05-092510 1:CAS:528:DC%2BD1cXjvVamtbk%3D
    • Sallmyr A, Fan J, Datta K, Kim KT, Grosu D, Shapiro P, Small D, Rassool F (2008) Internal tandem duplication of FLT3 (FLT3/ITD) induces increased ROS production, DNA damage, and misrepair: implications for poor prognosis in AML. Blood 111(6):3173-3182. doi: 10.1182/blood-2007-05-092510
    • (2008) Blood , vol.111 , Issue.6 , pp. 3173-3182
    • Sallmyr, A.1    Fan, J.2    Datta, K.3    Kim, K.T.4    Grosu, D.5    Shapiro, P.6    Small, D.7    Rassool, F.8
  • 43
    • 84866113642 scopus 로고    scopus 로고
    • The prognostic significance of cytokine levels in newly diagnosed acute myeloid leukemia and high-risk myelodysplastic syndromes
    • 10.1002/cncr.23785 18683214 10.1002/cncr.23785
    • Tsimberidou AM, Estey E, Wen S, Pierce S, Kantarjian H, Albitar M, Kurzrock R (2008) The prognostic significance of cytokine levels in newly diagnosed acute myeloid leukemia and high-risk myelodysplastic syndromes. Cancer 113(7):1605-1613. doi: 10.1002/cncr.23785
    • (2008) Cancer , vol.113 , Issue.7 , pp. 1605-1613
    • Tsimberidou, A.M.1    Estey, E.2    Wen, S.3    Pierce, S.4    Kantarjian, H.5    Albitar, M.6    Kurzrock, R.7
  • 44
    • 77956238512 scopus 로고    scopus 로고
    • Inhibition of STAT3 signaling blocks the anti-apoptotic activity of IL-6 in human liver cancer cells
    • 10.1074/jbc.M110.142752 20562100 10.1074/jbc.M110.142752 1:CAS:528:DC%2BC3cXhtVKhs7nL
    • Liu Y, Li PK, Li C, Lin J (2010) Inhibition of STAT3 signaling blocks the anti-apoptotic activity of IL-6 in human liver cancer cells. J Biol Chem 285(35):27429-27439. doi: 10.1074/jbc.M110.142752
    • (2010) J Biol Chem , vol.285 , Issue.35 , pp. 27429-27439
    • Liu, Y.1    Li, P.K.2    Li, C.3    Lin, J.4
  • 45
    • 77957013466 scopus 로고    scopus 로고
    • Direct inhibition of human acute myeloid leukemia cell growth by IL-12
    • 10.1016/j.imlet.2010.08.002 20705102 10.1016/j.imlet.2010.08.002 1:CAS:528:DC%2BC3cXht1Wju7bP
    • Ferretti E, Di Carlo E, Cocco C, Ribatti D, Sorrentino C, Ognio E, Montagna D, Pistoia V, Airoldi I (2010) Direct inhibition of human acute myeloid leukemia cell growth by IL-12. Immunol Lett 133(2):99-105. doi: 10.1016/j.imlet.2010.08.002
    • (2010) Immunol Lett , vol.133 , Issue.2 , pp. 99-105
    • Ferretti, E.1    Di Carlo, E.2    Cocco, C.3    Ribatti, D.4    Sorrentino, C.5    Ognio, E.6    Montagna, D.7    Pistoia, V.8    Airoldi, I.9
  • 46
    • 77649321216 scopus 로고    scopus 로고
    • Lunasin, with an arginine-glycine-aspartic acid motif, causes apoptosis to L1210 leukemia cells by activation of caspase-3
    • 10.1002/mnfr.200900073 19937853 10.1002/mnfr.200900073
    • de Mejia EG, Wang W, Dia VP (2010) Lunasin, with an arginine-glycine- aspartic acid motif, causes apoptosis to L1210 leukemia cells by activation of caspase-3. Mol Nutr Food Res 54(3):406-414. doi: 10.1002/mnfr.200900073
    • (2010) Mol Nutr Food Res , vol.54 , Issue.3 , pp. 406-414
    • De Mejia, E.G.1    Wang, W.2    Dia, V.P.3


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