Isolation, identification and molecular docking studies of a new isolated compound, from Onopordon acanthium: A novel Angiotensin Converting Enzyme (ACE) inhibitor

Journal of Ethnopharmacology

Volumn 148, Issue 3, 2013, Pages 934-939

  Sharifi, Niusha ^a   Souri, Effat ^a   Ziai, Seyed Ali ^b   Amin, Gholamreza ^a   Amini, Mohsen ^a,c   Amanlou, Massoud ^a,c  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Angiotensin Converting Enzyme; Antioxidant activity; Hypertension; Molecular docking; Onopordon acanthium

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; BUTYLCRESOL; CARDIOTONIC AGENT; DIPEPTIDYL CARBOXYPEPTIDASE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; HIPPURYLHISTIDYLLEUCINE; ONOPORDON ACANTHIUM EXTRACT; TROLOX C; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; ASTERACEAE; BINDING SITE; BLOOD BRAIN BARRIER; CARBON NUCLEAR MAGNETIC RESONANCE; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG ABSORPTION; DRUG BINDING; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG SOLUBILITY; DRUG SPECIFICITY; DRUG STRUCTURE; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IC 50; IN VITRO STUDY; INFRARED SPECTROSCOPY; INTESTINE ABSORPTION; MOLECULAR DOCKING; MOLECULAR MODEL; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ONOPORDON ACANTHIUM; PLASMA PROTEIN BINDING; PROTON NUCLEAR MAGNETIC RESONANCE; THIN LAYER CHROMATOGRAPHY; ULTRAVIOLET SPECTROPHOTOMETRY; X RAY DIFFRACTION;

ANGIOTENSIN CONVERTING ENZYME; ANTIOXIDANT ACTIVITY; HYPERTENSION; MOLECULAR DOCKING; ONOPORDON ACANTHIUM;

ACRYLATES; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ASTERACEAE; ISOCOUMARINS; MOLECULAR DOCKING SIMULATION; PLANT EXTRACTS; SEEDS;

ASTERACEAE; CIRSIUM; ONOPORDUM ACANTHIUM;

EID: 84880280917     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.05.046     Document Type: Article

References (28)

1. D.J. Campbell The renin-angiotensin and the kallikrein-kinin systems International Journal of Biochemistry & Cell Biology 35 2003 784 791
2. O.A. Carretero, and S. Oparil Essential hypertension. Part I: definition and etiology Circulation 101 2000 329 335
3. A. Cheng, and K.M. Merz Prediction of aqueous solubility of a diverse set of compounds using quantitative structure-property relationships Journal of Medicinal Chemistry 46 2003 3572 3580
4. G. Colmenarejo, A. Alvarez-Pedraglio, and J.L. Lavandera Cheminformatic models to predict binding affinities to human serum albumin Journal of Medicinal Chemistry 44 2001 4370 4378
5. H.R. Corradi, I. Chitapi, B.T. Sewell, D. Georgiadis, V. Dive, E.D. Sturrock, and K.R. Acharya The structure of testis angiotensin-converting enzyme in complex with the C domain-specific inhibitor RXPA380 Biochemistry 46 2007 5473 5478
6. D.W. Cushman, and H.S. Cheung Spectrophotometric assay and properties of the angiotensin-converting enzyme of rabbit lung Biochemical Pharmacology 20 1971 1637 1648
7. W.J. Egan, K.M.J.R. Merz, and J. Baldwin Prediction of drug absorption using multivariate statistics Journal of Medicinal Chemistry 43 2000 3867 3877
8. J.B. Harborne Phytochemical methods; A guide to modern techniques of plant analysis third ed. 1984 Champman and Hall London
9. R.J. Johnson, M.S. Segal, Y. Sautin, T. Nakagawa, D.I. Feig, and D.H. Kang Potential role of sugar (fructose) in the epidemic of hypertension, obesity and the metabolic syndrome, diabetes, kidney disease, and cardiovascular disease The American Journal of Clinical Nutrition 86 2007 899 906
10. P.M. Kearney, M. Whelton, K. Reynolds, P. Muntner, P.K. Whelton, and J. He Global burden of hypertension: analysis of worldwide data Lancet 365 2005 217 223
11. J. Kelder, P.D. Grootenhuis, D.M. Bayada, L.P. Delbressine, and J.P. Ploemen Polar molecular surface as a dominating determinant for oral absorption and brain penetration of drugs Pharmaceutical Research 16 1999 1514 1519
12. H.M. Kim, D.R. Shin, O.J. Yoo, H. Lee, and J. Lee Crystal structure of Drosophila angiotensin I-converting enzyme bound to captopril and lisinopril FEBS Letters 538 2003 65 70
13. E.K. Kwon, D.Y. Lee, H. Lee, D.O. Kim, N.I. Baek, Y.E. Kim, and H.Y. Kim Flavonoids from the buds of Rosa damascena inhibit the activity of 3-hydroxy-3-methylglutaryl-coenzyme a reductase and angiotensin I-converting enzyme Journal of Agricultural and Food Chemistry 58 2010 882 886
14. M.R. Loizzo, A. Said, R. Tundis, K. Rashed, G.A. Statti, A. Hufner, and F. Menichini Inhibition of angiotensin converting enzyme (ACE) by flavonoids isolated from Ailanthus excels (Roxb) (Simaroubaceae) Phytotherapy Research 21 2007 32 36
15. E. Mariani, C. Donarini, D. Grampella, T. Guerrerio, G. Landoni, and E. Portalupi Integrated treatment of cardiovascular common pathologies with conventional pharmacological therapy integrated with a typical remedy of anthroposophic medicine Cardiodoron (Onopordon/Primula comp) European Journal of Integrative Medicine 1 2009 223 260
16. E. Maugini Manuale di Botanica Farmaceutica seventh ed. 1994 Piccin Padova
17. A. Mehanna, and M. Dowling Liquid chromatographic determination of hippuric acid for the evaluation of ethacrynic acid as angiotensin converting enzyme inhibitor Journal of Pharmaceutical and Biomedical Analysis 19 1999 967 973
18. M.F. Montenegro, L.R. Pessa, and J.E. Tanus-Santos Isoflavone genistein inhibits the angiotensin converting enzyme and alters the vascular responses to angiotensin I and bradykinin European Journal of Pharmacology 607 2009 173 177
19. T. Morimoto, T.K. Gandhi, J.M. Fiskio, A.C. Seger, J.W. So, E.F. Cook, T. Fukui, and D.W. Bates An evaluation of risk factors for adverse drug events associated with angiotensin-converting enzyme inhibitors Journal of Evaluation in Clinical Practice 10 2004 499 509
20. G.M. Morris, D.S. Goodsell, R.S. Halliday, R. Huey, W.E. Hart, R.K. Belew, and A.J. Olson Automated docking using a Lamarckian genetic algorithm and an empirical binding free energy function Journal of Computational Chemistry 19 1998 1639 1662
21. H. Oh, D.G. Kang, J.W. Kwon, T.O. Kwon, S.Y. Lee, D.B. Lee, and H.B. Lee Isolation of angiotensin converting enzyme (ACE) inhibitory flavonoids from Sedum sarmentosum Biological and Pharmaceutical Bulletin 27 2004 2035 2037
22. D. Ojeda, E. Jiménez-Ferrer, A. Zamilpa, A. Herrera-Arellano, J. Tortoriello, and L. Alvarez Inhibition of angiotensin converting enzyme (ACE) activity by the anthocyanins delphinidin- and cyanidin-3-O-sambubiosides from Hibiscus sabdariffa Journal of Ethnopharmacology 127 2010 7 10
23. J.I. Ottaviani, L. Actis-Goretta, J.J. Villordo, and C.G. Fraga Procyanidin structure defines the extent and specificity of angiotensin I converting enzyme inhibition Biochimie 88 2006 359 365
24. L.T. Skeggs, J.E. Kahn, and N.P. Shumway The preparation and function of the angiotensin I converting enzyme Journal of Experimental Medicine 103 1956 295 299
25. J.I. Stokes, W.B. Kannel, P.A. Wolf, L.A Cupples, and R.B. D'Agostino The relative importance of selected risk factors for various manifestations of cardiovascular disease among men and women from 35 to 64 years old: 30 years of follow-up in the Framingham Study Circulation 75 1987 65 73
26. R.G. Susnow, and S.L. Dixon Use of robust classification techniques for of human cytochrome P450 2D6 inhibition Journal of Chemical Information and Computer sciences 43 2003 1308 1315
27. J.H.M. Van Esch, B. Tom, V. Dive, W.W. Batenburg, D. Georgiadis, A. Yiotakis, J.M.J. Van Gool, R.J.A. De Bruijn, R. De Vries, and A.H. Jan Danser Selective angiotensin-converting enzyme C domain inhibition is sufficient to prevent angiotensin I-induced vasoconstriction Hypertension 45 2005 120 125
28. G.C. Yen, and H.Y. Chen Antioxidant activity of various tea extracts in relation to their antimutagenicity Journal of Agricultural and Food Chemistry 43 1995 27 37