Short-lived her proteins drive robust synchronized oscillations in the Zebrafish segmentation clock

Development (Cambridge)

Volumn 140, Issue 15, 2013, Pages 3244-3253

  Ay, Ahmet ^a   Knierer, Stephan ^b   Sperlea, Adriana ^a   Holland, Jack ^a   Özbudak, Ertuǧrul M ^b  

^a Center for Language and Brain   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Computational modeling; Oscillation; Protein half life; Segmentation clock; Systems biology; Zebrafish

Indexed keywords

DIMER; EPIDERMAL GROWTH FACTOR HUMAN 1; EPIDERMAL GROWTH FACTOR HUMAN 7; GAMMA UROGASTRONE; HETERODIMER; NOTCH RECEPTOR; PROTEIN; PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; AUTOREGULATION; BIOLOGICAL MODEL; BIOLOGICAL RHYTHM; COMPUTER MODEL; CONTROLLED STUDY; EMBRYO; EMBRYO SEGMENTATION; GENE EXPRESSION; HALF LIFE TIME; MATHEMATICAL MODEL; MOLECULAR DYNAMICS; NEGATIVE FEEDBACK; NONHUMAN; OSCILLATION; OSCILLATOR; PREDICTION; PRIORITY JOURNAL; REPRESSOR GENE; SEGMENTATION CLOCK; SPINE; STOCHASTIC MODEL; TRANSCRIPTION REGULATION; VERTEBRATE; WILD TYPE;

COMPUTATIONAL MODELING; OSCILLATION; PROTEIN HALF-LIFE; SEGMENTATION CLOCK; SYSTEMS BIOLOGY; ZEBRAFISH;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BIOLOGICAL CLOCKS; BODY PATTERNING; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCKOUT TECHNIQUES; HALF-LIFE; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MEMBRANE PROTEINS; MODELS, BIOLOGICAL; MUTATION; RECEPTORS, NOTCH; SOMITES; STOCHASTIC PROCESSES; TRANSCRIPTION FACTORS; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84880277364     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.093278     Document Type: Article

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