Does hepatitis C viremia or genotype predict the risk of mortality in individuals co-infected with HIV?

Journal of Hepatology

Volumn 59, Issue 2, 2013, Pages 213-220

  Rockstroh, Jürgen K ^a   Peters, Lars ^b,c   Grint, Daniel ^d   Soriano, Vincent ^e   Reiss, Peter ^f   Monforte, Antonella D'Arminio ^g   Beniowski, Marek ^h   Losso, Marcelo H ⁱ   Kirk, Ole ^b,c   Kupfer, Bernd ^a   Mocroft, Amanda ^d  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c Rigshospitalet   (Denmark)

^d ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^e HOSPITAL UNIVERSITARIO LA PAZ   (Spain)

^f ACADEMIC MEDICAL CENTER   (Netherlands)

^g Clinica Malattie Infettive e Tropicali   (Italy)

^h Specialistic Hospital   (Poland)

ⁱ HOSPITAL RAMOS MEJÍA   (Argentina)

Author keywords

Genotype; Hepatitis C virus; HIV Co infection; Mortality; Viral load

Indexed keywords

VIRUS ANTIBODY;

ADULT; ARTICLE; DISEASE COURSE; DISEASE MARKER; FEMALE; GENOTYPE; HEPATITIS C; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; MAJOR CLINICAL STUDY; MALE; MIXED INFECTION; MORBIDITY; MORTALITY; PREDICTIVE VALUE; PRIORITY JOURNAL; PROGNOSIS; RISK ASSESSMENT;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; AIDS; ALANINE AMINOTRANSFERASE; ALT; ANTI-HCV ANTIBODY; BAC. INFECT; BACTERIAL INFECTION; CARDIOVASCULAR DISEASE; CART; CI; CO-INFECTION; COMBINATION ANTIRETROVIRAL THERAPY; CONFIDENCE INTERVAL; CVD; GENOTYPE; HAART; HBSAG; HBV; HCV; HCVAB; HEPATITIS B VIRUS; HEPATITIS B VIRUS SURFACE ANTIGEN; HEPATITIS C VIRUS; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HIV; HUMAN IMMUNODEFICIENCY VIRUS; IDU; INCIDENCE RATE RATIO; INJECTION DRUG USE; INTERNATIONAL UNITS/MILLILITRE; INTERQUARTILE RANGE; IQR; IRR; IU/ML; LIVER-RELATED DEATH; LRD; MORTALITY; PERSON-YEARS OF FOLLOW-UP; PYFU; RELATIVE HAZARD; RH; VIRAL LOAD;

ADULT; COHORT STUDIES; COINFECTION; DISEASE PROGRESSION; FEMALE; GENOTYPE; HEPATITIS C ANTIBODIES; HEPATITIS C, CHRONIC; HIV INFECTIONS; HIV-1; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RISK FACTORS; RNA, VIRAL; VIRAL LOAD; VIREMIA;

EID: 84880276440     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2013.04.005     Document Type: Article

References (33)

1. A. Alberti, N. Clumeck, S. Collins, W. Gerlich, J. Lundgren, and G. Palu Short statement of the first European Consensus Conference on the treatment of chronic hepatitis B and C in HIV co-infected patients J Hepatol 42 2005 615 624
2. C.W. Shepard, L. Finelli, and M.J. Alter Global epidemiology of hepatitis C virus infection Lancet Infect Dis 5 2005 558 567
3. V. Soriano, M. Puoti, M. Sulkowski, A. Cargnel, Y. Benhamou, and M. Peters Care of patients coinfected with HIV and hepatitis C virus: 2007 updated recommendations from the HCV-HIV International Panel AIDS 21 2007 1073 1089
4. B. Soto, A. Sanchez-Quijano, L. Rodrigo, J.A. del Olmo, M. Garcia-Bengoechea, and J. Hernandez-Quero Human immunodeficiency virus infection modifies the natural history of chronic parenterally-acquired hepatitis C with an unusually rapid progression to cirrhosis J Hepatol 26 1997 1 5
5. J.K. Rockstroh, U. Spengler, T. Sudhop, S. Ewig, A. Theisen, and U. Hammerstein Immunosuppression may lead to progression of hepatitis C virus-associated liver disease in hemophiliacs coinfected with HIV Am J Gastroenterol 91 1996 2563 2568
6. Y. Benhamou, V. Di Martino, M. Bochet, G. Colombet, V. Thibault, and A. Liou Factors affecting liver fibrosis in human immunodeficiency virus- and hepatitis C virus-coinfected patients: impact of protease inhibitor therapy Hepatology 34 2001 283 287
7. N. Brau, M. Salvatore, C.F. Rios-Bedoya, A. Fernandez-Carbia, F. Paronetto, and J.F. Rodriguez-Orengo Slower fibrosis progression in HIV/HCV-coinfected patients with successful HIV suppression using antiretroviral therapy J Hepatol 44 2006 47 55
8. N. Qurishi, C. Kreuzberg, G. Luchters, W. Effenberger, B. Kupfer, and T. Sauerbruch Effect of antiretroviral therapy on liver-related mortality in patients with HIV and hepatitis C virus coinfection Lancet 362 2003 1708 1713
9. M.E. Eyster, M.W. Fried, A.M. Di Bisceglie, and J.J. Goedert Increasing hepatitis C virus RNA levels in hemophiliacs: relationship to human immunodeficiency virus infection and liver disease. Multicenter Hemophilia Cohort Study Blood 84 1994 1020 1023
10. S.M. Gadalla, L.R. Preiss, M.E. Eyster, and J.J. Goedert Correlates of high hepatitis C virus RNA load in a cohort of HIV-negative and HIV-positive individuals with haemophilia J Viral Hepat 18 2011 161 169
11. L.N. Clausen, K. Astvad, S. Ladelund, M.V. Larsen, K. Schonning, and T. Benfield Hepatitis C viral load, genotype 3 and interleukin-28B CC genotype predict mortality in HIV and hepatitis C-coinfected individuals AIDS 26 2012 1509 1516
12. J.J. Goedert, A. Hatzakis, K.E. Sherman, and M.E. Eyster Lack of association of hepatitis C virus load and genotype with risk of end-stage liver disease in patients with human immunodeficiency virus coinfection J Infect Dis 184 2001 1202 1205
13. C.A. Sabin, P. Telfer, A.N. Phillips, S. Bhagani, and C.A. Lee The association between hepatitis C virus genotype and human immunodeficiency virus disease progression in a cohort of hemophilic men J Infect Dis 175 1997 164 168
14. M.M. Ahmed, D.J. Mutimer, B. Martin, E. Elias, and J.T. Wilde Hepatitis C viral load, genotype and histological severity in patients with bleeding disorders Haemophilia 5 1999 49 55
15. M.H. Lee, H.I. Yang, S.N. Lu, C.L. Jen, S.H. Yeh, and C.J. Liu Hepatitis C virus seromarkers and subsequent risk of hepatocellular carcinoma: long-term predictors from a community-based cohort study J Clin Oncol 28 2010 4587 4593
16. E. Herrero-Martinez, C.A. Sabin, J.G. Evans, A. Griffioen, C.A. Lee, and V.C. Emery The prognostic value of a single hepatitis C virus RNA load measurement taken early after human immunodeficiency virus seroconversion J Infect Dis 186 2002 470 476
17. A. Mocroft, B. Ledergerber, C. Katlama, O. Kirk, P. Reiss, and M.A. D'Arminio Decline in the AIDS and death rates in the EuroSIDA study: an observational study Lancet 362 2003 22 29
18. J.D. Kowalska, A. Mocroft, B. Ledergerber, E. Florence, M. Ristola, and J. Begovac A standardized algorithm for determining the underlying cause of death in HIV infection as AIDS or non-AIDS related: results from the EuroSIDA study HIV Clin Trials 12 2011 109 117
19. M. Bonacini, S. Louie, N. Bzowej, and A.R. Wohl Survival in patients with HIV infection and viral hepatitis B or C: a cohort study AIDS 18 2004 2039 2045
20. J.K. Rockstroh, A. Mocroft, V. Soriano, C. Tural, M.H. Losso, and A. Horban Influence of hepatitis C virus infection on HIV-1 disease progression and response to highly active antiretroviral therapy J Infect Dis 192 2005 992 1002
21. R. Weber, C.A. Sabin, N. Friis-Moller, P. Reiss, W.M. El-Sadr, and O. Kirk Liver-related deaths in persons infected with the human immunodeficiency virus: the D:A:D study Arch Intern Med 166 2006 1632 1641
22. N. Weis, B.O. Lindhardt, G. Kronborg, A.B. Hansen, A.L. Laursen, and P.B. Christensen Impact of hepatitis C virus coinfection on response to highly active antiretroviral therapy and outcome in HIV-infected individuals: a nationwide cohort study Clin Infect Dis 42 2006 1481 1487
23. A.C. Cardoso, R. Moucari, C. Figueiredo-Mendes, M.P. Ripault, N. Giuily, and C. Castelnau Impact of peginterferon and ribavirin therapy on hepatocellular carcinoma: incidence and survival in hepatitis C patients with advanced fibrosis J Hepatol 52 2010 652 657
24. J. Berenguer, E. Rodriguez, P. Miralles, M.A. von Wichmann, J. Lopez-Aldeguer, and J. Mallolas Sustained virological response to interferon plus ribavirin reduces non-liver-related mortality in patients coinfected with HIV and Hepatitis C virus Clin Infect Dis 55 2012 728 736
25. J. Berenguer, J. varez-Pellicer, P.M. Martin, J. Lopez-Aldeguer, M.A. Von-Wichmann, and C. Quereda Sustained virological response to interferon plus ribavirin reduces liver-related complications and mortality in patients coinfected with human immunodeficiency virus and hepatitis C virus Hepatology 50 2009 407 413
26. A.D. Branch, M.L. Van Natta, M.L. Vachon, D.T. Dieterich, C.L. Meinert, and D.A. Jabs Mortality in hepatitis C virus-infected patients with a diagnosis of AIDS in the era of combination antiretroviral therapy Clin Infect Dis 55 2012 137 144
27. M. Hoare, W.T. Gelson, S.M. Rushbrook, M.D. Curran, T. Woodall, and N. Coleman Histological changes in HCV antibody-positive, HCV RNA-negative subjects suggest persistent virus infection Hepatology 48 2008 1737 1745
28. L. Martin-Carbonero, P. Barreiro, G. Jimenez-Galan, R. Garcia-Berriguete, M. Nunez, and P. Rios Clearance of hepatitis C virus in HIV-infected patients with multiple chronic viral hepatitis J Viral Hepat 14 2007 392 395
29. I. Maida, M.J. Rios, L. Perez-Saleme, B. Ramos, V. Soriano, and P.S. Pegram Profile of patients triply infected with HIV and the hepatitis B and C viruses in the HAART era AIDS Res Hum Retroviruses 24 2008 679 683
30. G. Nkontchou, J.P. Bastard, M. Ziol, M. Aout, E. Cosson, and N. Ganne-Carrie Insulin resistance, serum leptin, and adiponectin levels and outcomes of viral hepatitis C cirrhosis J Hepatol 53 2010 827 833
31. J. Audsley, C.P. Du, Z. Goodman, C. McLean, A. Mijch, and S.R. Lewin HIV replication is associated with increased severity of liver biopsy changes in HIV-HBV and HIV-HCV co-infection J Med Virol 84 2012 993 1001
32. D. Posthouwer, M. Makris, T.T. Yee, K. Fischer, J.J. Van Veen, and A. Griffioen Progression to end-stage liver disease in patients with inherited bleeding disorders and hepatitis C: an international, multicenter cohort study Blood 109 2007 3667 3671
33. P. Bonnard, F.X. Lescure, C. Amiel, J.B. Guiard-Schmid, P. Callard, and S. Gharakhanian Documented rapid course of hepatic fibrosis between two biopsies in patients coinfected by HIV and HCV despite high CD4 cell count J Viral Hepat 14 2007 806 811