Correlates of high hepatitis C virus RNA load in a cohort of HIV-negative and HIV-positive individuals with haemophilia

Journal of Viral Hepatitis

Volumn 18, Issue 3, 2011, Pages 161-169

  Gadalla, S M ^a,b   Preiss, L R ^c   Eyster, M E ^d   Goedert, J J ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b National Institute of Heath   (United States)

^c RTI INTERNATIONAL   (United States)

^d PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

haemophilia; HCV load; HCV HIV co infection

Indexed keywords

ASPARTATE AMINOTRANSFERASE; INTERFERON; VIRUS RNA;

ADOLESCENT; ADULT; AGED; ARTICLE; BODY MASS; CONTROLLED STUDY; DISEASE COURSE; DISEASE DURATION; FEMALE; HEMOPHILIA; HEPATITIS C; HEPATITIS C VIRUS; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; MALE; MIXED INFECTION; PRIORITY JOURNAL; THROMBOCYTE; TREATMENT FAILURE; VIREMIA; VIROTHERAPY; VIRUS LOAD;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; COHORT STUDIES; HEMOPHILIA A; HEPACIVIRUS; HEPATITIS C; HIV; HIV INFECTIONS; HUMANS; LIVER FUNCTION TESTS; LOGISTIC MODELS; LYMPHOCYTE COUNT; MALE; MIDDLE AGED; PLATELET COUNT; RNA, VIRAL; VIRAL LOAD; VIREMIA; YOUNG ADULT;

EID: 79951476165     PISSN: 13520504     EISSN: 13652893     Source Type: Journal    
DOI: 10.1111/j.1365-2893.2010.01289.x     Document Type: Article

References (40)

1. Brettler DB, Alter HJ, Dienstag JL, Forsberg AD, Levine PH,. Prevalence of hepatitis C virus antibody in a coho (Pubitemid 20220818)
2. Rumi MG, Colombo M, Gringeri A, Mannucci PM,. High prevalence of antibody to hepatitis C virus in multitransfused hemophiliacs with normal transaminase levels. Ann.Intern.Med. 1990; 112 (5): 379-380. (Pubitemid 20083614)
3. Schramm W, Roggendorf M, Rommel F, et al. Prevalence of antibodies to hepatitis C virus (HCV) in haemophiliacs. Blut 1989; 59 (4): 390-392. (Pubitemid 20050646)
4. Goedert JJ, Chen BE, Preiss L, Aledort LM, Rosenberg PS,. Reconstruction of the hepatitis C virus epidemic in the US hemophilia population, 1940-1990. Am.J.Epidemiol. 2007; 12: 1443-1453. (Pubitemid 47234309)
5. Goedert JJ,. Prevalence of conditions associated with human immunodeficiency and hepatitis virus infections among persons with haemophilia, 2001-2003. Haemophilia. 2005; 11 (5): 516-528. (Pubitemid 41283122)
6. Seeff LB,. Natural history of hepatitis C. Hepatology 1997; 26 (3 Suppl 1): 21S-28S. (Pubitemid 27388067)
7. Goedert JJ, Eyster ME, Lederman MM, et al. End-stage liver disease in persons with hemophilia and transfusion-associated infections. Blood 2002; 100 (5): 1584-1589. (Pubitemid 34925132)
8. Hisada M, O'Brien TR, Rosenberg PS, Goedert JJ,. Virus load and risk of heterosexual transmission of human immunodeficiency virus and hepatitis C virus by men with hemophilia. The Multicenter Hemophilia Cohort Study. J.Infect.Dis. 2000; 181 (4): 1475-1478. (Pubitemid 30252559)
9. Tajiri H, Miyoshi Y, Funada S, et al. Prospective study of mother-to-infant transmission of hepatitis C virus. Pediatr.Infect.Dis.J. 2001; 20 (1): 10-14. (Pubitemid 32066170)
10. Gretch D, Corey L, Wilson J, et al. Assessment of hepatitis C virus RNA levels by quantitative competitive RNA polymerase chain reaction: high-titer viremia correlates with advanced stage of disease. J.Infect.Dis. 1994; 169 (6): 1219-1225. (Pubitemid 24164583)
11. Kato N, Yokosuka O, Hosoda K, Ito Y, Ohto M, Omata M,. Quantification of hepatitis C virus by competitive reverse transcription-polymerase chain reaction: increase of the virus in advanced liver disease. Hepatology 1993; 18 (1): 16-20. (Pubitemid 23193611)
12. Hisada M, Chatterjee N, Kalaylioglu Z, Battjes RJ, Goedert JJ,. Hepatitis C virus load and survival among injection drug users in the United States. Hepatology 2005; 42 (6): 1446-1452. (Pubitemid 43260049)
13. McHutchison JG, Gordon SC, Schiff ER, et al. Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C. Hepatitis Interventional Therapy Group. N.Engl.J.Med. 1998; 339 (21): 1485-1492. (Pubitemid 28543496)
14. Shiffman ML, Suter F, Bacon BR, et al. Peginterferon alfa-2a and ribavirin for 16 or 24 weeks in HCV genotype 2 or 3. N.Engl.J.Med. 2007; 357 (2): 124-134. (Pubitemid 47057730)
15. Zeuzem S, Diago M, Gane E, et al. Peginterferon alfa-2a (40 kilodaltons) and ribavirin in patients with chronic hepatitis C and normal aminotransferase levels. Gastroenterology 2004; 127 (6): 1724-1732. (Pubitemid 39575851)
16. Hoofnagle JH, Wahed AS, Brown Jr RS, Howell CD, Belle SH,. Early Changes in Hepatitis C Virus (HCV) Levels in Response to Peginterferon and Ribavirin Treatment in Patients with Chronic HCV Genotype 1 Infection. J.Infect.Dis. 2009; 199 (8): 1112-1120.
17. Fishbein DA, Lo Y, Netski D, Thomas DL, Klein RS,. Predictors of hepatitis C virus RNA levels in a prospective cohort study of drug users. J.Acquir.Immune Defic.Syndr. 2006; 41 (4): 471-476.
18. Operskalski EA, Mack WJ, Strickler HD, et al. Factors associated with hepatitis C viremia in a large cohort of HIV-infected and -uninfected women. J.Clin.Virol. 2008; 41 (4): 255-263.
19. Hofmann H,. Genotypes and virus load in patients with hepatitis C infection. Infection 1995; 23 (3): 133-138.
20. Adinolfi LE, Utili R, Andreana A, et al. Serum HCV RNA levels correlate with histological liver damage and concur with steatosis in progression of chronic hepatitis C. Dig.Dis.Sci. 2001; 46 (8): 1677-1683. (Pubitemid 32727098)
21. Hsu CS, Liu CH, Liu CJ, et al. Association of lipid profiles with hepatitis C viral load in chronic hepatitis C patients with genotype 1 or 2 infection. Am.J.Gastroenterol. 2009; 104 (3): 598-604.
22. Eyster ME, Sherman KE, Goedert JJ, Katsoulidou A, Hatzakis A,. Prevalence and changes in hepatitis C virus genotypes among multitransfused persons with hemophilia. The Multicenter Hemophilia Cohort Study. J.Infect.Dis. 1999; 179 (5): 1062-1069. (Pubitemid 29196483)
23. Sabin CA, Emery V, Devereux HL, et al. Long-term patterns of hepatitis C virus RNA concentrations in a cohort of HIV seronegative men with bleeding disorders. J.Med.Virol. 2002; 68 (1): 68-75. (Pubitemid 34827173)
24. Eyster ME, Fried MW, Di Bisceglie AM, Goedert JJ,. Increasing hepatitis C virus RNA levels in hemophiliacs: relationship to human immunodeficiency virus infection and liver disease. Multicenter Hemophilia Cohort Study. Blood 1994; 84 (4): 1020-1023. (Pubitemid 24245863)
25. Zhang M, Rosenberg PS, Brown DL, et al. Correlates of spontaneous clearance of hepatitis C virus among people with hemophilia. Blood 2006; 107 (3): 892-897. (Pubitemid 43156284)
26. Pialoux G,. Efficacy of peginterferon plus ribavirin for HIV-HCV co-infection. Results of the APRICOT study. Presse Med. 2005; 34 (20 Pt 2): 1589-1591. (Pubitemid 43010088)
27. Crespo M, Sauleda S, Esteban JI, et al. Peginterferon alpha-2b plus ribavirin vs interferon alpha-2b plus ribavirin for chronic hepatitis C in HIV-coinfected patients. J.Viral Hepat. 2007; 14 (4): 228-238. (Pubitemid 46452410)
28. Giannini E, Risso D, Botta F, et al. Validity and clinical utility of the aspartate aminotransferase-alanine aminotransferase ratio in assessing disease severity and prognosis in patients with hepatitis C virus-related chronic liver disease. Arch.Intern.Med. 2003; 163 (2): 218-224. (Pubitemid 36120190)
29. Lackner C, Struber G, Liegl B, et al. Comparison and validation of simple noninvasive tests for prediction of fibrosis in chronic hepatitis C. Hepatology 2005; 41 (6): 1376-1382. (Pubitemid 40770291)
30. Thomas DL, Astemborski J, Vlahov D, et al. Determinants of the quantity of hepatitis C virus RNA. J.Infect.Dis. 2000; 181 (3): 844-851. (Pubitemid 30194464)
31. Wai CT, Greenson JK, Fontana RJ, et al. A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C. Hepatology 2003; 38 (2): 518-526. (Pubitemid 36919874)
32. Yeung LT, To T, King SM, Roberts EA,. Spontaneous clearance of childhood hepatitis C virus infection. J.Viral Hepat. 2007; 14 (11): 797-805. (Pubitemid 47561585)
33. Messick K, Sanders JC, Goedert JJ, Eyster ME,. Hepatitis C viral clearance and antibody reactivity patterns in persons with haemophilia and other congenital bleeding disorders. Haemophilia. 2001; 7 (6): 568-574. (Pubitemid 34026751)
34. Ragni MV, Bontempo FA,. Increase in hepatitis C virus load in hemophiliacs during treatment with highly active antiretroviral therapy. J.Infect.Dis. 1999; 180 (6): 2027-2029.
35. Bani-Sadr F, Goderel I, Morand P, et al. High hepatitis C virus viral load in HIV/hepatitis C virus-co-infected patients: a different influence of protease inhibitor and non-protease inhibitor-based HAART? AIDS 2007; 21 (12): 1645-1648. (Pubitemid 47075489)
36. Sherman KE, Shire NJ, Cernohous P, et al. Liver injury and changes in hepatitis C Virus (HCV) RNA load associated with protease inhibitor-based antiretroviral therapy for treatment-naive HCV-HIV-coinfected patients: lopinavir-ritonavir versus nelfinavir. Clin.Infect.Dis. 2005; 41 (8): 1186-1195. (Pubitemid 41429484)
37. Ticehurst JR, Hamzeh FM, Thomas DL,. Factors affecting serum concentrations of hepatitis C virus (HCV) RNA in HCV genotype 1-infected patients with chronic hepatitis. J.Clin.Microbiol. 2007; 45 (8): 2426-2433. (Pubitemid 47295469)
38. Palmer C, Corpuz T, Guirguis M, et al. The effect of obesity on intrahepatic cytokine and chemokine expression in chronic hepatitis C infection. Gut 2009; [Epub ahead of print].
39. Reiberger T, Aberle JH, Kundi M, et al. IP-10 correlates with hepatitis C viral load, hepatic inflammation and fibrosis and predicts hepatitis C virus relapse or non-response in HIV-HCV coinfection. Antivir.Ther. 2008; 13 (8): 969-976.
40. Lin CS, Chang CS, Yang SS, Yeh HZ, Lin CW,. Retrospective evaluation of serum markers APRI and AST/ALT for assessing liver fibrosis and cirrhosis in chronic hepatitis B and C patients with hepatocellular carcinoma. Intern.Med. 2008; 47 (7): 569-575.