Novel antidepressant-like activity of propolis extract mediated by enhanced glucocorticoid receptor function in the hippocampus

Evidence-based Complementary and Alternative Medicine

Volumn 2013, Issue , 2013, Pages

  Lee, Mi Sook ^a,b   Kim, Young Han ^a   Park, Wan Soon ^a   Ahn, Won Gyeong ^a   Park, Ok Kyu ^a   Kwon, Seung Hae ^a   Morita, Kyoji ^c   Shim, Insop ^b   Her, Song ^a  

^a Korea Basic Science Institute (KBSI)   (South Korea)

^b Kyung Hee University   (South Korea)

^c SHIKOKU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTERONE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FLUOXETINE; GLUCOCORTICOID RECEPTOR; PROPOLIS; PROTEIN C FOS;

ANIMAL EXPERIMENT; ANTIDEPRESSANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DENTATE GYRUS; DOWN REGULATION; FORCED SWIMMING TEST; HIPPOCAMPUS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMOBILIZATION; IMMUNOREACTIVITY; LOCOMOTION; MALE; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; STRESS; WESTERN BLOTTING;

EID: 84880241326     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2013/217853     Document Type: Article

References (45)

1. Bankova V., Recent trends and important developments in propolis research. Evidence-based Complementary and Alternative Medicine 2005 2 1 29 32 2-s2.0-23044479136 10.1093/ecam/neh059
2. Oršolić N., Šaranović A. B., Bašić I., Direct and indirect mechanism(s) of antitumour activity of propolis and its polyphenolic compounds. Planta Medica 2006 72 1 20 27 2-s2.0-32644434209 10.1055/s-2005-873167
3. Krol W., Czuba Z., Scheller S., Gabrys J., Grabiec S., Shani J., Anti-oxidant property of ethanolic extract of propolis (EEP) as evaluated by inhibiting the chemiluminescence oxidation of luminol. Biochemistry International 1990 21 4 593 597 2-s2.0-0024995675
4. Sforcin J. M., Fernandes A. Jr., Lopes C. A. M., Bankova V., Funari S. R. C., Seasonal effect on Brazilian propolis antibacterial activity. Journal of Ethnopharmacology 2000 73 1-2 243 249 2-s2.0-0033806545 10.1016/S0378-8741(00) 00320-2
5. Shimazawa M., Chikamatsu S., Morimoto N., Mishima S., Nagai H., Hara H., Neuroprotection by Brazilian green propolis against in vitro and in vivo ischemic neuronal damage. Evidence-based Complementary and Alternative Medicine 2005 2 2 201 207 2-s2.0-24344461279 10.1093/ecam/neh078
6. Orsi R. O., Sforcin J. M., Funari S. R. C., Bankova V., Effects of Brazilian and Bulgarian propolis on bactericidal activity of macrophages against Salmonella Typhimurium. International Immunopharmacology 2005 5 2 359 368 2-s2.0-12344281942 10.1016/j.intimp.2004.10.003
7. Freitas S. F., Shinohara L., Sforcin J. M., Guimarães S., In vitro effects of propolis on Giardia duodenalis trophozoites. Phytomedicine 2006 13 3 170 175 2-s2.0-31044455355 10.1016/j.phymed.2004.07.008
8. Li Y.-J., Xuan H.-Z., Shou Q.-Y., Zhan Z.-G., Lu X., Hu F.-L., Therapeutic effects of propolis essential oil on anxiety of restraint-stressed mice. Human and Experimental Toxicology 2012 31 2 157 165 2-s2.0-84858670359 10.1177/0960327111412805
9. Orsatti C. L., Sforcin J. M., Propolis immunomodulatory activity on TLR-2 and TLR-4 expression by chronically stressed mice. Natural Product Research 2012 26 5 446 453 2-s2.0-84857622838 10.1080/14786419.2010.482049
10. Twardowska K., Rybakowski J., Limbic-hypothalamic-pituitary-adrenal axis in depression (literature review). Psychiatria Polska 1996 30 5 741 755 2-s2.0-0029850948
11. Cubała W. J., Landowski J., Serotoninergic system and limbic-hypothalamic-pituitary-adrenal axis (LHPA axis) in depression. Psychiatria Polska 2006 40 3 415 430 2-s2.0-33747422130
12. Reul J. M. H. M., van den Bosch F. R., de Kloet E. R., Relative occupation of type-I and type-II corticosteroid receptors in rat brain following stress and dexamethasone treatment: functional implications. Journal of Endocrinology 1987 115 3 459 467 2-s2.0-0023473436
13. Webster M. J., Knable M. B., O'Grady J., Orthmann J., Weickert C. S., Regional specificity of brain glucocorticoid receptor mRNA alterations in subjects with schizophrenia and mood disorders. Molecular Psychiatry 2002 7 9 985 994 2-s2.0-0036428858 10.1038/sj.mp.4001139
14. McGowan P. O., Sasaki A., D'Alessio A. C., Dymov S., Labonté B., Szyf M., Turecki G., Meaney M. J., Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse. Nature Neuroscience 2009 12 3 342 348 2-s2.0-60749105468 10.1038/nn.2270
15. McQuade R., Young A. H., Future therapeutic targets in mood disorders: the glucocorticoid receptor. The British Journal of Psychiatry 2000 177 390 395 2-s2.0-0033767639 10.1192/bjp.177.5.390
16. Anacker C., Zunszain P. A., Cattaneo A., Carvalho L. A., Garabedian M. J., Thuret S., Price J., Pariante C. M., Antidepressants increase human hippocampal neurogenesis by activating the glucocorticoid receptor. Molecular Psychiatry 2011 16 7 738 750 2-s2.0-79959586058 10.1038/mp.2011.26
17. Seckl J. R., Fink G., Antidepressants increase glucocorticoid and mineralocorticoid receptor mRNA expression in rat hippocampus in vivo. Neuroendocrinology 1992 55 6 621 626 2-s2.0-0026594730
18. Wang Z., Frederick J., Garabedian M. J., Deciphering the phosphorylation "code" of the glucocorticoid receptor in vivo. Journal of Biological Chemistry 2002 277 29 26573 26580 2-s2.0-0037135596 10.1074/jbc.M110530200
19. Kumar R., Calhoun W. J., Differential regulation of the transcriptional activity of the glucocorticoid receptor through site-specific phosphorylation. Biologics 2008 2 4 845 854 2-s2.0-77952664545
20. Rogatsky I., Logan S. K., Garabedian M. J., Antagonism of glucocorticoid receptor transcriptional activation by the c-Jun N-terminal kinase. Proceedings of the National Academy of Sciences of the United States of America 1998 95 5 2050 2055 2-s2.0-0032478254 10.1073/pnas.95.5.2050
21. Ismaili N., Garabedian M. J., Modulation of glucocorticoid receptor function via phosphorylation. Annals of the New York Academy of Sciences 2004 1024 86 101 2-s2.0-3042788350 10.1196/annals.1321.007
22. Lee M. S., Park W. S., Kim Y. H., Antidepressant-like effects of Cortex Mori Radicis extract via bidirectional phosphorylation of glucocorticoid receptors in the hippocampus. Behavioural Brain Research 2013 236 1 56 61
23. Föcking M., Hölker I., Trapp T., Chronic glucocorticoid receptor activation impairs CREB transcriptional activity in clonal neurons. Biochemical and Biophysical Research Communications 2003 304 4 720 723 2-s2.0-0037449162 10.1016/S0006-291X(03)00665-X
24. Díaz-Gallardo M. Y., Cote-Vélez A., Charli J. L., Joseph-Bravo P., A rapid interference between glucocorticoids and cAMP-activated signalling in hypothalamic neurones prevents binding of phosphorylated cAMP response element binding protein and glucocorticoid receptor at the CRE-Like and composite GRE Sites of thyrotrophin-releasing hormone gene promoter. Journal of Neuroendocrinology 2010 22 4 282 293 2-s2.0-77952488508 10.1111/j.1365-2826. 2010.01966.x
25. Porsolt R. D., Anton G., Blavet N., Jalfre M., Behavioural despair in rats: a new model sensitive to antidepressant treatments. The European Journal of Pharmacology 1978 47 4 379 391 2-s2.0-0018268297
26. Steru L., Chermat R., Thierry B., Simon P., The tail suspension test: a new method for screening antidepressants in mice. Psychopharmacology 1985 85 3 367 370 2-s2.0-0021990491
27. Zomkowski A. D. E., Engel D., Gabilan N. H., Rodrigues A. L. S., Involvement of NMDA receptors and l-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effects of escitalopram in the forced swimming test. The European Neuropsychopharmacology 2010 20 11 793 801 2-s2.0-77957019472 10.1016/j.euroneuro.2010.07.011
28. Paxinos G., Watson C., The Rat Brain in Stereotaxic Coordinates 2005 San Diego, CA, USA Elsevier
29. Lee M.-S., Kwon E.-H., Choi H.-S., Kwon S.-H., Lee C.-H., Shim I.-S., Lee S.-K., Her S., Quantification of cellular uptake and in vivo tracking of transduction using real-time monitoring. Biochemical and Biophysical Research Communications 2010 394 2 348 353 2-s2.0-77950189694 10.1016/j.bbrc.2010.03.009
30. Adzic M., Djordjevic J., Djordjevic A., Niciforovic A., Demonacos C., Radojcic M., Krstic-Demonacos M., Acute or chronic stress induce cell compartment-specific phosphorylation of glucocorticoid receptor and alter its transcriptional activity in Wistar rat brain. Journal of Endocrinology 2009 202 1 87 97 2-s2.0-67650753710 10.1677/JOE-08-0509
31. Gonzalez G. A., Yamamoto K. K., Fischer W. H., Karr D., Menzel P., Biggs W. III, Vale W. W., Montminy M. R., A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence. Nature 1989 337 6209 749 752 2-s2.0-0024499494
32. Redrobe J. P., Pinot P., Bourin M., The effect of the potassium channel activator, cromakalim, on antidepressant drugs in the forced swimming test in mice. Fundamental and Clinical Pharmacology 1996 10 6 524 528 2-s2.0-0029851929
33. Lucki I., Dalvi A., Mayorga A. J., Sensitivity to the effects of pharmacologically selective antidepressants in different strains of mice. Psychopharmacology 2001 155 3 315 322 2-s2.0-0035017384 10.1007/s002130100694
34. Adelman W. P., Tobacco Use Cessation for Adolescents. Adolescent Medicine Clinics 2006 17 3 697 717 2-s2.0-33749337060 10.1016/j.admecli.2006.06.013
35. Ha J., Choi H.-S., Lee Y., Lee Z. H., Kim H.-H., Caffeic acid phenethyl ester inhibits osteoclastogenesis by suppressing NF B and downregulating NFATc1 and c-Fos. International Immunopharmacology 2009 9 6 774 780 2-s2.0-67349241906 10.1016/j.intimp.2009.03.001
36. de Kloet E. R., Vreugdenhil E., Oitzl M. S., Joëls M., Brain corticosteroid receptor balance in health and disease. Endocrine Reviews 1998 19 3 269 301 2-s2.0-0032467785
37. Yau J. L. W., Olsson T., Morris R. G. M., Meaney M. J., Seckl J. R., Glucocorticoids, hippocampal corticosteroid receptor gene expression and antidepressant treatment: relationship with spatial learning in young and aged rats. Neuroscience 1995 66 3 571 581 2-s2.0-0029032247 10.1016/0306-4522(94) 00612-9
38. Bei E., Salpeas V., Pappa D., Anagnostara C., Alevizos V., Moutsatsou P., Phosphorylation status of glucocorticoid receptor, heat shock protein 70, cytochrome c and Bax in lymphocytes of euthymic, depressed and manic bipolar patients. Psychoneuroendocrinology 2009 34 8 1162 1175 2-s2.0-67650739234 10.1016/j.psyneuen.2009.03.002
39. Simic I., Maric N. P., Mitic M., Phosphorylation of leukocyte glucocorticoid receptor in patients with current episode of major depressive disorder. Progress in Neuro-Psychopharmacology and Biological Psychiatry 2013 40 281 285
40. Yamada S., Yamamoto M., Ozawa H., Riederer P., Saito T., Reduced phosphorylation of cyclic AMP-responsive element binding protein in the postmortem orbitofrontal cortex of patients with major depressive disorder. Journal of Neural Transmission 2003 110 6 671 680 2-s2.0-0037507158 10.1007/s00702-002-0810-8
41. Koch J. M., Kell S., Hinze-Selch D., Aldenhoff J. B., Changes in CREB-phosphorylation during recovery from major depression. Journal of Psychiatric Research 2002 36 6 369 375 2-s2.0-0036830532 10.1016/S0022-3956(02) 00056-0
42. Lyons D. M., Buckmaster P. S., Lee A. G., Wu C., Mitra R., Duffey L. M., Buckmaster C. L., Her S., Patel P. D., Schatzberg A. F., Stress coping stimulates hippocampal neurogenesis in adult monkeys. Proceedings of the National Academy of Sciences of the United States of America 2010 107 33 14823 14827 2-s2.0-77957088311 10.1073/pnas.0914568107
43. Carlezon W. A. Jr., Duman R. S., Nestler E. J., The many faces of CREB. Trends in Neurosciences 2005 28 8 436 445 2-s2.0-22144467379 10.1016/j.tins.2005.06.005
44. Kurauchi Y., Hisatsune A., Isohama Y., Caffeic acid phenethyl ester protects nigral dopaminergic neurons via dual mechanisms involving haem oxygenase-1 and brain-derived neurotrophic factor. The British Journal of Pharmacology 2012 166 3 1151 1168
45. Takeda H., Tsuji M., Yamada T., Masuya J., Matsushita K., Tahara M., Iimori M., Matsumiya T., Caffeic acid attenuates the decrease in cortical BDNF mRNA expression induced by exposure to forced swimming stress in mice. The European Journal of Pharmacology 2006 534 1-3 115 121 2-s2.0-33644918269 10.1016/j.ejphar.2006.01.026