메뉴 건너뛰기




Volumn 20, Issue 11, 2010, Pages 793-801

Involvement of NMDA receptors and l-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effects of escitalopram in the forced swimming test

Author keywords

Depression; Escitalopram; Forced swimming test; L arginine; NMDA; Tail suspension test

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; 7 NITROINDAZOLE; ARGININE; CYCLIC GMP; ESCITALOPRAM; METHYLENE BLUE; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; NITRIC OXIDE; SILDENAFIL;

EID: 77957019472     PISSN: 0924977X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.euroneuro.2010.07.011     Document Type: Article
Times cited : (82)

References (58)
  • 1
    • 32044447470 scopus 로고    scopus 로고
    • Evidence for the involvement of l-arginine-nitric oxide cyclic guanosine monophosphate pathway in the antidepressant-like effect of memantine in mice
    • Almeida R.C., Felisbino C.S., López M.G., Rodrigues A.L.S., Gabilan N.H. Evidence for the involvement of l-arginine-nitric oxide cyclic guanosine monophosphate pathway in the antidepressant-like effect of memantine in mice. Behav. Brain Res. 2006, 168:318-322.
    • (2006) Behav. Brain Res. , vol.168 , pp. 318-322
    • Almeida, R.C.1    Felisbino, C.S.2    López, M.G.3    Rodrigues, A.L.S.4    Gabilan, N.H.5
  • 2
    • 0028802726 scopus 로고
    • Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms
    • Beavo J.A. Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms. Physiol. Rev. 1995, 75:725-748.
    • (1995) Physiol. Rev. , vol.75 , pp. 725-748
    • Beavo, J.A.1
  • 4
    • 62849094914 scopus 로고    scopus 로고
    • Ascorbic acid administration produces an antidepressant-like effect: evidence for the involvement of monoaminergic neurotransmission
    • Binfaré R.W., Rosa A.O., Lobato K.R., Santos A.R.S., Rodrigues A.L.S. Ascorbic acid administration produces an antidepressant-like effect: evidence for the involvement of monoaminergic neurotransmission. Prog. Neuropsychopharmacol. Biol. Psychiatry 2009, 33:530-540.
    • (2009) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.33 , pp. 530-540
    • Binfaré, R.W.1    Rosa, A.O.2    Lobato, K.R.3    Santos, A.R.S.4    Rodrigues, A.L.S.5
  • 5
    • 0035100705 scopus 로고    scopus 로고
    • How valuable are animal models in defining antidepressant activity?
    • Bourin M., Fiocco A.J., Clenet F. How valuable are animal models in defining antidepressant activity?. Hum Psychopharm. 2001, 16:9-21.
    • (2001) Hum Psychopharm. , vol.16 , pp. 9-21
    • Bourin, M.1    Fiocco, A.J.2    Clenet, F.3
  • 6
    • 0031751159 scopus 로고    scopus 로고
    • Chronic administration of imipramine and citalopram alters the expression of NMDA receptor subunit mRNAs in mouse brain
    • Boyer P.A., Skolnick P., Fossom L.H. Chronic administration of imipramine and citalopram alters the expression of NMDA receptor subunit mRNAs in mouse brain. A quantitative in situ hybridization study. J. Mol. Neurosci. 1998, 10:219-233.
    • (1998) A quantitative in situ hybridization study. J. Mol. Neurosci. , vol.10 , pp. 219-233
    • Boyer, P.A.1    Skolnick, P.2    Fossom, L.H.3
  • 7
    • 33746902947 scopus 로고    scopus 로고
    • Genetic inactivation of the NMDA receptor NR2A subunit has anxiolytic- and antidepressant-like effects in mice
    • Boyce-Rustay J.M., Holmes A. Genetic inactivation of the NMDA receptor NR2A subunit has anxiolytic- and antidepressant-like effects in mice. Neuropsychopharmacology 2006, 31:2405-2411.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 2405-2411
    • Boyce-Rustay, J.M.1    Holmes, A.2
  • 8
    • 54049141605 scopus 로고    scopus 로고
    • Antidepressant-like effect of folic acid: involvement of NMDA receptors and l-arginine-nitric oxide-cyclic guanosine monophosphate pathway
    • Brocardo P.S., Budni J., Lobato K.R., Kaster M.P., Rodrigues A.L.S. Antidepressant-like effect of folic acid: involvement of NMDA receptors and l-arginine-nitric oxide-cyclic guanosine monophosphate pathway. Eur. J. Pharmacol. 2008, 598:37-42.
    • (2008) Eur. J. Pharmacol. , vol.598 , pp. 37-42
    • Brocardo, P.S.1    Budni, J.2    Lobato, K.R.3    Kaster, M.P.4    Rodrigues, A.L.S.5
  • 9
    • 27144516427 scopus 로고    scopus 로고
    • A randomized, double-blind, 24-week study of escitalopram (10mg/day) versus citalopram (20mg/day) in primary care patients with major depressive disorder
    • Colonna L., Andersen H.F., Reines E.H. A randomized, double-blind, 24-week study of escitalopram (10mg/day) versus citalopram (20mg/day) in primary care patients with major depressive disorder. Curr. Med. Res. Opin. 2005, 21:1659-1668.
    • (2005) Curr. Med. Res. Opin. , vol.21 , pp. 1659-1668
    • Colonna, L.1    Andersen, H.F.2    Reines, E.H.3
  • 10
    • 0034103659 scopus 로고    scopus 로고
    • Roles of NMDA receptor activity and nitric oxide production in brain development
    • Contestabile A. Roles of NMDA receptor activity and nitric oxide production in brain development. Brain Res. Rev. 2000, 32:476-509.
    • (2000) Brain Res. Rev. , vol.32 , pp. 476-509
    • Contestabile, A.1
  • 11
    • 19944380200 scopus 로고    scopus 로고
    • The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice
    • Cryan J.F., Mombereau C., Vassout A. The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice. Neurosci. Biobehav. Rev. 2005, 9:571-625.
    • (2005) Neurosci. Biobehav. Rev. , vol.9 , pp. 571-625
    • Cryan, J.F.1    Mombereau, C.2    Vassout, A.3
  • 12
    • 0034722589 scopus 로고    scopus 로고
    • Evidence for dual effects of nitric oxide in the forced swimming test and in the tail suspension test in mice
    • Da Silva G., Matteussi A., Santos A.R.S., Calixto J.B., Rodrigues A.L.S. Evidence for dual effects of nitric oxide in the forced swimming test and in the tail suspension test in mice. NeuroReport 2000, 11:3699-3702.
    • (2000) NeuroReport , vol.11 , pp. 3699-3702
    • Da Silva, G.1    Matteussi, A.2    Santos, A.R.S.3    Calixto, J.B.4    Rodrigues, A.L.S.5
  • 13
    • 0032902722 scopus 로고    scopus 로고
    • Guanylate cyclase and the NO/cGMP signaling pathway
    • Denninger J.W., Marletta M.A. Guanylate cyclase and the NO/cGMP signaling pathway. Biochim. Biophys. Acta 1999, 1411:334-350.
    • (1999) Biochim. Biophys. Acta , vol.1411 , pp. 334-350
    • Denninger, J.W.1    Marletta, M.A.2
  • 14
    • 34247489688 scopus 로고    scopus 로고
    • Involvement of l-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of venlafaxine in mice
    • Dhir A., Kulkarni S.K. Involvement of l-arginine-nitric oxide-cyclic guanosine monophosphate pathway in the antidepressant-like effect of venlafaxine in mice. Prog. Neuropsychopharmacolo. Biol. Psychiatry 2007, 31:921-925.
    • (2007) Prog. Neuropsychopharmacolo. Biol. Psychiatry , vol.31 , pp. 921-925
    • Dhir, A.1    Kulkarni, S.K.2
  • 15
    • 33845318214 scopus 로고    scopus 로고
    • Prevention of pro-depressant effect of l-arginine in the forced swim test by NG-nitro-l-arginine and [1H-[1, 2, 4]Oxadiazole[4, 3-a]quinoxalin- 1-one]
    • Ergün Y., Ergün U.G. Prevention of pro-depressant effect of l-arginine in the forced swim test by NG-nitro-l-arginine and [1H-[1, 2, 4]Oxadiazole[4, 3-a]quinoxalin- 1-one]. Eur. J. Pharmacol. 2007, 554:150-154.
    • (2007) Eur. J. Pharmacol. , vol.554 , pp. 150-154
    • Ergün, Y.1    Ergün, U.G.2
  • 16
    • 0031280496 scopus 로고    scopus 로고
    • Anxiolytic and antidepressant properties of methylene blue in animal models
    • Eroglu L., Caglayan B. Anxiolytic and antidepressant properties of methylene blue in animal models. Pharmacol. Res. 1997, 36:381-385.
    • (1997) Pharmacol. Res. , vol.36 , pp. 381-385
    • Eroglu, L.1    Caglayan, B.2
  • 17
    • 0036196417 scopus 로고    scopus 로고
    • NO as a signalling molecule in the nervous system
    • Esplugues J.V. NO as a signalling molecule in the nervous system. Brit. J. Pharmacol. 2002, 135:1079-1095.
    • (2002) Brit. J. Pharmacol. , vol.135 , pp. 1079-1095
    • Esplugues, J.V.1
  • 19
    • 40749102904 scopus 로고    scopus 로고
    • Nitric oxide involvement in the antidepressant-like effects of acute lithium administration in the mouse forced swimming test
    • Ghasemi M., Sadeghipour H., Mosleh A., Sadeghipour H.R., Mani A.R., Dehpour A.R. Nitric oxide involvement in the antidepressant-like effects of acute lithium administration in the mouse forced swimming test. Eur. Neuropsychopharmacol. 2008, 18:323-332.
    • (2008) Eur. Neuropsychopharmacol. , vol.18 , pp. 323-332
    • Ghasemi, M.1    Sadeghipour, H.2    Mosleh, A.3    Sadeghipour, H.R.4    Mani, A.R.5    Dehpour, A.R.6
  • 20
    • 69549126138 scopus 로고    scopus 로고
    • NMDA/receptor nitregirc system blockage augments antidepressant-like effects of paroxetine in the mouse forced swimming test
    • Ghasemi M., Montaser-Kouhsari L., Shafarodi H., Nezami B.G., Ebrahimi F., Dehpour A.R. NMDA/receptor nitregirc system blockage augments antidepressant-like effects of paroxetine in the mouse forced swimming test. Psychopharmacology 2009, 206:325-333.
    • (2009) Psychopharmacology , vol.206 , pp. 325-333
    • Ghasemi, M.1    Montaser-Kouhsari, L.2    Shafarodi, H.3    Nezami, B.G.4    Ebrahimi, F.5    Dehpour, A.R.6
  • 21
    • 77950377037 scopus 로고    scopus 로고
    • NMDA receptor antagonists augment antidepressant-like effects of lithium in the mouse forced swimming test
    • Ghasemi M., Raza M., Dehpour A. NMDA receptor antagonists augment antidepressant-like effects of lithium in the mouse forced swimming test. J. Psychopharmacol. 2010, 24:585-594.
    • (2010) J. Psychopharmacol. , vol.24 , pp. 585-594
    • Ghasemi, M.1    Raza, M.2    Dehpour, A.3
  • 23
    • 0037382381 scopus 로고    scopus 로고
    • Serotonergic mediation of the antidepressant-like effects of nitric oxide synthase inhibitors
    • Harkin A.J., Connor T.J., Walsh M., St John N., Kelly J.P. Serotonergic mediation of the antidepressant-like effects of nitric oxide synthase inhibitors. Neuropharmacology 2003, 44:616-623.
    • (2003) Neuropharmacology , vol.44 , pp. 616-623
    • Harkin, A.J.1    Connor, T.J.2    Walsh, M.3    St John, N.4    Kelly, J.P.5
  • 24
    • 2442478088 scopus 로고    scopus 로고
    • Nitric oxide inhibitors augment the effects of serotonin re-uptake inhibitors in the forced swimming test
    • Harkin A., Connor T.J., Burns M.P., Kelly J.P. Nitric oxide inhibitors augment the effects of serotonin re-uptake inhibitors in the forced swimming test. Eur. Neuropsychopharmacol. 2004, 14:274-281.
    • (2004) Eur. Neuropsychopharmacol. , vol.14 , pp. 274-281
    • Harkin, A.1    Connor, T.J.2    Burns, M.P.3    Kelly, J.P.4
  • 25
    • 35848939420 scopus 로고    scopus 로고
    • Increased levels of glutamate in brains from patients with mood disorders
    • Hashimoto K., Sawa A., Iyo M. Increased levels of glutamate in brains from patients with mood disorders. Biol. Psychiatry 2007, 62:1310-1316.
    • (2007) Biol. Psychiatry , vol.62 , pp. 1310-1316
    • Hashimoto, K.1    Sawa, A.2    Iyo, M.3
  • 26
    • 0037151298 scopus 로고    scopus 로고
    • Reduction of cGMP and nitric oxide has antidepressant like effects in the forced swimming test in rats
    • Heiberg I.L., Wegener G., Rosenberg R. Reduction of cGMP and nitric oxide has antidepressant like effects in the forced swimming test in rats. Behav. Brain. Res. 2002, 134:479-484.
    • (2002) Behav. Brain. Res. , vol.134 , pp. 479-484
    • Heiberg, I.L.1    Wegener, G.2    Rosenberg, R.3
  • 27
    • 0026539075 scopus 로고
    • The pharmacological effect of citalopram resides in the (S)-(+)-enantiomer
    • Hyttel J., Bogeso K.P., Perregaard J., Sánchez C. The pharmacological effect of citalopram resides in the (S)-(+)-enantiomer. J. Neural Transm. Gen. 1992, 88:157-160.
    • (1992) J. Neural Transm. Gen. , vol.88 , pp. 157-160
    • Hyttel, J.1    Bogeso, K.P.2    Perregaard, J.3    Sánchez, C.4
  • 28
    • 42249096435 scopus 로고    scopus 로고
    • Escitalopram for the treatment of major depression and anxiety disorders
    • Höschl C., Svestka J. Escitalopram for the treatment of major depression and anxiety disorders. Expert. Rev. Neurother. 2008, 8:537-552.
    • (2008) Expert. Rev. Neurother. , vol.8 , pp. 537-552
    • Höschl, C.1    Svestka, J.2
  • 29
    • 33645103130 scopus 로고    scopus 로고
    • Inhibition of neuronal nitric oxide synthase in the rat hippocampus induces antidepressant-like effects
    • Joca S.R., Guimarães F.S. Inhibition of neuronal nitric oxide synthase in the rat hippocampus induces antidepressant-like effects. Psychopharmacology 2006, 185:298-305.
    • (2006) Psychopharmacology , vol.185 , pp. 298-305
    • Joca, S.R.1    Guimarães, F.S.2
  • 30
    • 27644452327 scopus 로고    scopus 로고
    • Effect of potassium channel inhibitors in the forced swimming test: possible involvement of l-arginine-nitric oxide-soluble guanylate cyclase pathway
    • Kaster M.P., Ferreira P.K., Santos A.R.S., Rodrigues A.L.S. Effect of potassium channel inhibitors in the forced swimming test: possible involvement of l-arginine-nitric oxide-soluble guanylate cyclase pathway. Behav. Brain Res. 2005, 165:204-209.
    • (2005) Behav. Brain Res. , vol.165 , pp. 204-209
    • Kaster, M.P.1    Ferreira, P.K.2    Santos, A.R.S.3    Rodrigues, A.L.S.4
  • 31
    • 25844498636 scopus 로고    scopus 로고
    • Involvement of nitric oxide-cGMP pathway in the antidepressant-like effects of adenosine in the forced swimming test
    • Kaster M.P., Rosa A.O., Santos A.R., Rodrigues A.L. Involvement of nitric oxide-cGMP pathway in the antidepressant-like effects of adenosine in the forced swimming test. Int. J. Neuropsychopharmacol. 2005, 8:601-606.
    • (2005) Int. J. Neuropsychopharmacol. , vol.8 , pp. 601-606
    • Kaster, M.P.1    Rosa, A.O.2    Santos, A.R.3    Rodrigues, A.L.4
  • 32
    • 34547484479 scopus 로고    scopus 로고
    • Possible involvement of l-arginine-nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signaling pathway in the antidepressant-like activity of berberine chloride
    • Kulkarni S.K., Dhir A. Possible involvement of l-arginine-nitric oxide (NO)-cyclic guanosine monophosphate (cGMP) signaling pathway in the antidepressant-like activity of berberine chloride. Eur. J. Pharmacol. 2007, 569:77-83.
    • (2007) Eur. J. Pharmacol. , vol.569 , pp. 77-83
    • Kulkarni, S.K.1    Dhir, A.2
  • 33
    • 54049133688 scopus 로고    scopus 로고
    • Escitalopram and duloxetine in the treatment of major depressive disorder: a pooled analysis of two trials
    • Lam R.W., Andersen H.F., Wade A.G. Escitalopram and duloxetine in the treatment of major depressive disorder: a pooled analysis of two trials. Int. Clin. Psychopharmacol. 2008, 23:181-187.
    • (2008) Int. Clin. Psychopharmacol. , vol.23 , pp. 181-187
    • Lam, R.W.1    Andersen, H.F.2    Wade, A.G.3
  • 34
    • 0035903772 scopus 로고    scopus 로고
    • Asymmetrical reductions of hippocampal NMDAR1 glutamate receptor mRNA in the psychoses
    • Law A.J., Deakin J.F. Asymmetrical reductions of hippocampal NMDAR1 glutamate receptor mRNA in the psychoses. Neuroreport 2001, 12:2971-2974.
    • (2001) Neuroreport , vol.12 , pp. 2971-2974
    • Law, A.J.1    Deakin, J.F.2
  • 35
    • 1642422744 scopus 로고    scopus 로고
    • Nitric oxide in brain: diffusion, targets and concentration dynamics in hippocampal subregions
    • Ledo A., Frade J., Barbosa R.M., Laranjinha J. Nitric oxide in brain: diffusion, targets and concentration dynamics in hippocampal subregions. Mol. Aspects Med. 2004, 25:75-89.
    • (2004) Mol. Aspects Med. , vol.25 , pp. 75-89
    • Ledo, A.1    Frade, J.2    Barbosa, R.M.3    Laranjinha, J.4
  • 36
    • 33745039466 scopus 로고    scopus 로고
    • Nitric oxide, cell bioenergetics and neurodegeneration
    • Moncada S., Bolaños J.P. Nitric oxide, cell bioenergetics and neurodegeneration. J. Neurochem. 2006, 16:1676-1689.
    • (2006) J. Neurochem. , vol.16 , pp. 1676-1689
    • Moncada, S.1    Bolaños, J.P.2
  • 37
    • 17644423099 scopus 로고    scopus 로고
    • Prospective, multicentre, randomized, double-blind study of the efficacy of escitalopram versus citalopram in outpatient treatment of major depressive disorder
    • Moore N., Verdoux H., Fantino B. Prospective, multicentre, randomized, double-blind study of the efficacy of escitalopram versus citalopram in outpatient treatment of major depressive disorder. Int. Clin. Psychopharmacol. 2005, 20:131-137.
    • (2005) Int. Clin. Psychopharmacol. , vol.20 , pp. 131-137
    • Moore, N.1    Verdoux, H.2    Fantino, B.3
  • 38
    • 0028900455 scopus 로고
    • Alterations in the N-methyl-d-aspartate (NMDA) receptor complex in the frontal cortex of suicide victims
    • Nowak G., Ordway G.A., Paul I.A. Alterations in the N-methyl-d-aspartate (NMDA) receptor complex in the frontal cortex of suicide victims. Brain Res. 1995, 675:157-164.
    • (1995) Brain Res. , vol.675 , pp. 157-164
    • Nowak, G.1    Ordway, G.A.2    Paul, I.A.3
  • 39
    • 0346461630 scopus 로고    scopus 로고
    • Glutamate and depression: clinical and preclinical studies
    • Paul I.A., Skolnick P. Glutamate and depression: clinical and preclinical studies. Ann. N. Y. Acad. Sci. 2003, 1003:250-272.
    • (2003) Ann. N. Y. Acad. Sci. , vol.1003 , pp. 250-272
    • Paul, I.A.1    Skolnick, P.2
  • 40
    • 0017651126 scopus 로고
    • Behavioral despair in mice: a primary screening test for antidepressants
    • Porsolt R.D., Bertin A., Jalfre M. Behavioral despair in mice: a primary screening test for antidepressants. Arch. Int. Pharmacodyn. Ther. 1977, 229:327-336.
    • (1977) Arch. Int. Pharmacodyn. Ther. , vol.229 , pp. 327-336
    • Porsolt, R.D.1    Bertin, A.2    Jalfre, M.3
  • 41
    • 0036065596 scopus 로고    scopus 로고
    • Synergistic effect of uncompetitive NMDA receptor antagonists and antidepressant drugs in the forced swimming test in rats
    • Rogóz Z., Skuza G., Maj J., Danysz W. Synergistic effect of uncompetitive NMDA receptor antagonists and antidepressant drugs in the forced swimming test in rats. Neuropsychopharmacology 2002, 42:1024-1030.
    • (2002) Neuropsychopharmacology , vol.42 , pp. 1024-1030
    • Rogóz, Z.1    Skuza, G.2    Maj, J.3    Danysz, W.4
  • 43
    • 0042388369 scopus 로고    scopus 로고
    • Involvement of NMDA receptors and l-arginine-nitric oxide pathway in the antidepressant-like effects of zinc in mice
    • Rosa A.O., Lin J., Calixto J.B., Santos A.R.S., Rodrigues A.L.S. Involvement of NMDA receptors and l-arginine-nitric oxide pathway in the antidepressant-like effects of zinc in mice. Behav. Brain Res. 2003, 144:87-93.
    • (2003) Behav. Brain Res. , vol.144 , pp. 87-93
    • Rosa, A.O.1    Lin, J.2    Calixto, J.B.3    Santos, A.R.S.4    Rodrigues, A.L.S.5
  • 44
    • 42949123365 scopus 로고    scopus 로고
    • Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders
    • Sanacora G., Zarate C.A., Krystal J.H., Manji H.K. Targeting the glutamatergic system to develop novel, improved therapeutics for mood disorders. Nature Rev Drug Disc. 2008, 7:426-437.
    • (2008) Nature Rev Drug Disc. , vol.7 , pp. 426-437
    • Sanacora, G.1    Zarate, C.A.2    Krystal, J.H.3    Manji, H.K.4
  • 45
    • 0038508859 scopus 로고    scopus 로고
    • Escitalopram, the S-(+)-enantiomer of citalopram, is a selective serotonin reuptake inhibitor with potent effects in animal models predictive of antidepressant and anxiolytic activities
    • Sánchez C., Bergqvist P.B.F., Brennum L.T., Gupta S., Hogg S., Larsen A., Wiborg O. Escitalopram, the S-(+)-enantiomer of citalopram, is a selective serotonin reuptake inhibitor with potent effects in animal models predictive of antidepressant and anxiolytic activities. Psychopharmacology 2003, 167:353-362.
    • (2003) Psychopharmacology , vol.167 , pp. 353-362
    • Sánchez, C.1    Bergqvist, P.B.F.2    Brennum, L.T.3    Gupta, S.4    Hogg, S.5    Larsen, A.6    Wiborg, O.7
  • 46
    • 0142074886 scopus 로고    scopus 로고
    • R-citalopram counteracts the effect of escitalopram in a rat conditioned fear stress model of anxiety
    • Sánchez C., Gruca P., Bien E., Papp M. R-citalopram counteracts the effect of escitalopram in a rat conditioned fear stress model of anxiety. Pharmacol. Biochem. Behav. 2003, 75:903-907.
    • (2003) Pharmacol. Biochem. Behav. , vol.75 , pp. 903-907
    • Sánchez, C.1    Gruca, P.2    Bien, E.3    Papp, M.4
  • 48
    • 0032983086 scopus 로고    scopus 로고
    • Antidepressants for the new millennium
    • Skolnick P. Antidepressants for the new millennium. Eur. J. Pharmacol. 1999, 375:31-40.
    • (1999) Eur. J. Pharmacol. , vol.375 , pp. 31-40
    • Skolnick, P.1
  • 49
    • 0021990491 scopus 로고
    • The tail suspension test: a new method for screening antidepressants in mice
    • Steru L., Chermat R., Thierry B., Simon P. The tail suspension test: a new method for screening antidepressants in mice. Psychopharmacology 1985, 85:367-370.
    • (1985) Psychopharmacology , vol.85 , pp. 367-370
    • Steru, L.1    Chermat, R.2    Thierry, B.3    Simon, P.4
  • 51
    • 35848941499 scopus 로고    scopus 로고
    • Direct inhibitory effect of fluoxetine on N-methyl-d-aspartate receptors in the central nervous system
    • Szasz B.K., Mike A., Karoly R., Gerevich Z., Illes P., Vizi E.S., Kiss J.P. Direct inhibitory effect of fluoxetine on N-methyl-d-aspartate receptors in the central nervous system. Biol. Psychiatry 2007, 62:1303-1309.
    • (2007) Biol. Psychiatry , vol.62 , pp. 1303-1309
    • Szasz, B.K.1    Mike, A.2    Karoly, R.3    Gerevich, Z.4    Illes, P.5    Vizi, E.S.6    Kiss, J.P.7
  • 52
    • 48749127299 scopus 로고    scopus 로고
    • Neuronal NOS inhibitor 1-(2-trifluoromethylphenyl)-imidazole augment the effects of antidepressants acting via serotonergic system in the forced swimming test in rats
    • Ulak G., Mutlu O., Akar F.Y., Komsuoǧlu F.I., Tanyeri P., Erden B.F. Neuronal NOS inhibitor 1-(2-trifluoromethylphenyl)-imidazole augment the effects of antidepressants acting via serotonergic system in the forced swimming test in rats. Pharmacol. Biochem. Behav. 2008, 90:563-568.
    • (2008) Pharmacol. Biochem. Behav. , vol.90 , pp. 563-568
    • Ulak, G.1    Mutlu, O.2    Akar, F.Y.3    Komsuoǧlu, F.I.4    Tanyeri, P.5    Erden, B.F.6
  • 53
    • 0344520448 scopus 로고    scopus 로고
    • Antidepressant- and anxiolytic-like effects of selective neuronal NOS inhibitor 1-(2-trifluoromethylphenyl)-imidazole in mice
    • Volke V., Wegener G., Bourin M., Vasar E. Antidepressant- and anxiolytic-like effects of selective neuronal NOS inhibitor 1-(2-trifluoromethylphenyl)-imidazole in mice. Behav. Brain Res. 2003, 140:141-147.
    • (2003) Behav. Brain Res. , vol.140 , pp. 141-147
    • Volke, V.1    Wegener, G.2    Bourin, M.3    Vasar, E.4
  • 54
    • 0037414735 scopus 로고    scopus 로고
    • Local, but not systemic administration of serotonergic antidepressants decreases hippocampal nitric oxide synthase activity
    • Wegener G., Volke V., Harvey B.H., Rosenberg R. Local, but not systemic administration of serotonergic antidepressants decreases hippocampal nitric oxide synthase activity. Brain Res. 2003, 959:128-134.
    • (2003) Brain Res. , vol.959 , pp. 128-134
    • Wegener, G.1    Volke, V.2    Harvey, B.H.3    Rosenberg, R.4
  • 55
    • 0035348160 scopus 로고    scopus 로고
    • Research and treatment approaches to depression
    • Wong M.L., Licinio J. Research and treatment approaches to depression. Nat Rev Neurosci 2001, 2:343-351.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 343-351
    • Wong, M.L.1    Licinio, J.2
  • 56
    • 0034110759 scopus 로고    scopus 로고
    • Antidepressant-like effect of 7-nitroindazole in the forced swimming test in rats
    • Yildiz F., Erden B.F., Ulak G., Utkan T., Gacar N. Antidepressant-like effect of 7-nitroindazole in the forced swimming test in rats. Psychopharmacology 2000, 149:41-44.
    • (2000) Psychopharmacology , vol.149 , pp. 41-44
    • Yildiz, F.1    Erden, B.F.2    Ulak, G.3    Utkan, T.4    Gacar, N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.