Dissecting the anticipation of aversion reveals dissociable neural networks

Cerebral Cortex

Volumn 23, Issue 8, 2013, Pages 1874-1883

  Grupe, Daniel W ^a,b   Oathes, Desmond J ^a,d   Nitschke, Jack B ^a,b,c  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b Department of Psychology ^*  (United States)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

^d STANFORD UNIVERSITY   (United States)

Author keywords

amygdala; anterior insula; BNST; fMRI; rostral cingulate

Indexed keywords

ADULT; ANTERIOR CINGULATE; ANTERIOR INSULA; ANTERIOR MID CINGULATE CORTEX; ANTICIPATORY ANXIETY; ARTICLE; BEHAVIOR; DEFENSIVE BEHAVIOR; FEMALE; FOREBRAIN; HUMAN; HUMAN EXPERIMENT; INTEROCEPTION; MALE; MESENCEPHALON; NERVE CELL NETWORK; NORMAL HUMAN; ORBITAL CORTEX; PREGENUAL ANTERIOR CINGULATE CORTEX; PRIORITY JOURNAL; STRIA TERMINALIS;

AMYGDALA; ANTERIOR INSULA; BNST; FMRI; ROSTRAL CINGULATE;

ADULT; ANTICIPATION, PSYCHOLOGICAL; ANXIETY; BRAIN; EMOTIONS; FEMALE; HUMANS; MALE; NERVE NET; YOUNG ADULT;

EID: 84880238001     PISSN: 10473211     EISSN: 14602199     Source Type: Journal    
DOI: 10.1093/cercor/bhs175     Document Type: Article

References (58)

1. Alvarez RP, Chen G, Bodurka J, Kaplan R, Grillon C. 2011. Phasic and sustained fear in humans elicits distinct patterns of brain activity. Neuroimage. 55:389-400.
2. An X, Bandler R, Ongur D, Price JL. 1998. Prefrontal cortical projections to longitudinal columns in the midbrain periaqueductal gray in macaque monkeys. J Comp Neurol. 401:455-479.
3. Bandler R, Keay KA, Floyd N, Price J. 2000. Central circuits mediating patterned autonomic activity during active vs. passive emotional coping. Brain Res Bull. 53:95-104.
4. Barlow DH. 2000. Unraveling the mysteries of anxiety and its disorders from the perspective of emotion theory. Am Psychol. 55:1247-1263.
5. Birbaumer N, Elbert T, Canavan AGM, Rockstroh B. 1990. Slow potentials of the cerebral cortex and behavior. Physiol Rev. 70:1-41.
6. Böcker KBE, Baas JMP, Kenemans KL, Verbaten MN. 2001. Stimulus-preceding negativity induced by fear: a manifestation of affective anticipation. Int J Psychophysiol. 43:77-90.
7. Borkovec TD. 2002. Life in the future versus life in the present. Clin Psychol Sci Prac. 9:76.-80.
8. Bromberg-Martin ES, Matsumoto M, Hikosaka O. 2010. Dopamine in motivational control: rewarding, aversive, and alerting. Neuron. 68:815-834.
9. Carlson JM, Greenberg T, Rubin D, Mujica-Parodi LR. 2011. Feeling anxious: anticipatory amygdalo-insular response predicts the feeling of anxious anticipation. Soc Cogn Affect Neurosci. 6:74-81.
10. Cox RW. 1996. AFNI: software for analysis and visualization of functional magnetic resonance neuroimages. J Biomed Inform. 29:162-173.
11. Craig AD. 2002. How do you feel? Interoception: the sense of the physiological condition of the body. Nat Rev Neurosci. 3:655-666.
12. Craig AD. 2009. How do you feel-now? The anterior insula and human awareness. Nat Rev Neurosci. 10:59-70.
13. Critchley HD. 2005. Neural mechanisms of autonomic, affective, and cognitive integration. J Comp Neurol. 493:154-166.
14. Critchley HD. 2009. Psychophysiology of neural, cognitive and affective integration: fMRI and autonomic indicants. Int J Psychophy-siol. 73:88-94.
15. Critchley HD, Wiens S, Rotshtein P, Ohman A, Dolan RJ. 2004. Neural systems supporting interoceptive awareness. Nat Neurosci. 7:189-195.
16. Davis M, Walker DL, Miles L, Grillon C. 2010. Phasic vs. sustained fear in rats and humans: role of the extended amygdala in fear vs. anxiety. Neuropsychopharmacology. 35:105-135.
17. Davis M, Whalen PJ. 2001. The amygdala: vigilance and emotion. Mol Psychiatry. 6:13-34.
18. Drabant EM, Kuo JR, Ramel W, Blechert J, Edge MD, Cooper JR, Goldin PR, Hariri AR, Gross JJ. 2011. Experiential, autonomic, and neural responses during threat anticipation vary as a function of threat intensity and neuroticism. Neuroimage. 55:401-410.
19. First MB, Spitzer RL, Gibbon M, Williams JBW. 2002. Structured Clinical Interview for DSM-IV-TR Axis I Disorders, Research Version (SCID-I). New York: Biometrics Research.
20. Fox AS, Shelton SE, Oakes TR, Converse AK, Davidson RJ, Kalin NH. 2010. Orbitofrontal cortex lesions alter anxiety-related activity in the primate bed nucleus of stria terminalis. J Neurosci. 30:7023-7027.
21. Friston KJ, Büchel C, Fink GR, Morris J, Rolls E, Dolan RJ. 1997. Psy-chophysiological and modulatory interactions in neuroimaging. Neuroimage. 6:218-229.
22. Herwig U, Baumgartner T, Kaffenberger T, Bruhl A, Kottlow M, Schreiter-Gasser U, Abler B, Jancke L, Rufer M. 2007. Modulation of anticipatory emotion and perception processing by cognitive control. Neuroimage. 37:652-662.
23. Kalin NH, Shelton SE, Davidson RJ. 2004. The role of the central nucleus of the amygdala in mediating fear and anxiety in the primate. J Neurosci. 24:5506-5515.
24. Kalisch R, Wiech K, Critchley HD, Dolan RJ. 2006. Levels of appraisal: a medial prefrontal role in high-level appraisal of emotional material. Neuroimage. 30:1458-1466.
25. Kalisch R, Wiech K, Critchley HD, Seymour B, O'Doherty JP, Oakley DA, Allen P, Dolan RJ. 2005. Anxiety reduction through detachment: subjective, physiological, and neural effects. J Cogn Neurosci. 17:874-883.
26. Kumari V, ffytche DH, Das M, Wilson GD, Goswami S, Sharma T. 2007. Neuroticism and brain responses to anticipatory fear. Behav Neurosci. 121:643-652.
27. Lang PJ, Bradley MM, Cuthbert BN. 2008. International affective picture system (IAPS): affective ratings of pictures and instruction manual. Technical Report A-8. Gainesville (FL): University of Florida.
28. LeDoux JE. 2000. Emotion circuits in the brain. Annu Rev Neurosci. 23:155-184.
29. Linnman C, Moulton EA, Barmettler G, Becerra L, Borsook D. 2012. Neuroimaging of the periaqueductal gray: state of the field. Neuroimage. 60:505-522.
30. Lissek S, Pine DS, Grillon C. 2006. The strong situation: a potential impediment to studying the psychobiology and pharmacology of anxiety disorders. Biol Psychol. 72:265-270.
31. Lorberbaum JP, Kose S, Johnson MR, Arana GW, Sullivan LK, Hamner MB, Ballenger JC, Lydiard RB, Brodrick PS, Bohning DE et al. 2004. Neural correlates of speech anticipatory anxiety in generalized social phobia. Neuroreport. 15:2701-2705.
32. Mackiewicz KL, Sarinopoulos I, Cleven KL, Nitschke JB. 2006. The effect of anticipation and the specificity of sex differences for amygdala and hippocampus function in emotional memory. Proc Natl Acad Sci USA. 103:14200-14205.
33. Mai JK, Assheuer J, Paxinos G. 1998. Atlas of the human brain. San Diego, CA: Academic Press. Electronic version 1.0
34. McDonald AJ, Shammah-Lagnado SJ, Shi C, Davis M. 1999. Cortical afferents to the extended amygdala. Ann N Y Acad Sci. 877: 309-338.
35. Mechias ML, Etkin A, Kalisch R. 2010. A meta-analysis of instructed fear studies: implications for conscious appraisal of threat. Neuroimage. 49:1760-1768.
36. Meyer TJ, Miller ML, Metzger RL, Borkovec TD. 1990. Development and validation of the Penn State Worry Questionnaire. Behav Res Ther. 28:487-495.
37. Milad MR, Quirk GJ, Pitman RK, Orr SP, Fischl B, Rauch SL. 2007. A role for the human dorsal anterior cingulate cortex in fear expression. Biol Psychiatry. 62:1191-1194.
38. Mobbs D, Marchant JL, Hassabis D, Seymour B, Tan G, Gray M, Petro-vic P, Dolan RJ, Frith CD. 2009. From threat to fear: the neural organization of defensive fear systems in humans. J Neurosci. 29:12236-12243.
39. Mobbs D, Petrovic P, Marchant JL, Hassabis D, Weiskopf N, Seymour B, Dolan RJ, Frith CD. 2007. When fear is near: threat imminence elicits prefrontal-periaqueductal gray shifts in humans. Science. 317:1079-1083.
40. Mobbs D, Yu R, Rowe JB, Eich H, FeldmanHall O, Dalgleish T. 2010. Neural activity associated with monitoring the oscillating threat value of a tarantula. Proc Natl Acad Sci USA. 107:20582-20586.
41. Nitschke JB, Sarinopoulos I, Mackiewicz KL, Schaefer HS, Davidson RJ. 2006. Functional neuroanatomy of aversion and its anticipation. Neuroimage. 29:106-116.
42. Nitschke JB, Sarinopoulos I, Oathes DJ, Johnstone T, Whalen PJ, Davidson RJ, Kalin NH. 2009. Anticipatory activation in the amygdala and anterior cingulate in generalized anxiety disorder and prediction of treatment response. Am J Psychiatry. 166:302-310.
43. Phelps EA, O'Connor KJ, Gatenby JC, Gore JC, Grillon C, Davis M. 2001. Activation of the left amygdala to a cognitive representation of fear. Nat Neurosci. 4:437-441.
44. Ploghaus A, Tracey I, Gati JS, Clare S, Menon RS, Matthews PM, Rawlins JN. 1999. Dissociating pain from its anticipation in the human brain. Science. 284:1979-1981.
45. Ploner M, Lee MC, Wiech K, Bingel U, Tracey I. 2010. Prestimulus functional connectivity determines pain perception in humans Proc Natl Acad Sci USA. 107:355-360.
46. Saygin ZM, Osher DE, Augustinack J, Fischl B, Gabrieli JDE. 2011. Connectivity-based segmentation of human amygdala nuclei using probabilistic tractography. Neuroimage. 56:1353-1361.
47. Shackman AJ, Salomons TV, Slagter HA, Fox AS, Winter JJ, Davidson RJ. 2011. The integration of negative affect, pain and cognitive control in the cingulate cortex. Nat Rev Neurosci. 12:154-167.
48. Simmons A, Strigo I, Matthews SC, Paulus MP, Stein MB. 2006. Anticipation of aversive visual stimuli is associated with increased insula activation in anxiety-prone subjects. Biol Psychiatry. 60:402-409.
49. Simmons AN, Stein MB, Strigo IA, Arce E, Hitchcock C, Paulus MP. 2011. Anxiety positive subjects show altered processing in the anterior insula during anticipation of negative stimuli. Hum Brain Mapp. 32:1836-1846.
50. Somerville LH, Wagner DD, Wig GS, Moran JM, Whalen PJ, Kelley WM. 2012. Interactions between brief and persistent neural signals support the generation and regulation of anxious emotion. Cereb Cortex. Epub ahead of print. doi: 10.1093/cercor/bhr373.
51. Somerville LH, Whalen PJ, Kelley WM. 2010. Human bed nucleus of the stria terminalis indexes hypervigilant threat monitoring. Biol Psychiatry. 68:416-424.
52. Stein MB, Simmons AN, Feinstein JS, Paulus MP. 2007. Increased amygdala and insula activation during emotion processing in anxiety-prone subjects. Am J Psychiatry. 164:318-327.
53. Straube T, Mentzel HJ, Miltner WH. 2007. Waiting for spiders: brain activation during anticipatory anxiety in spider phobics. Neuroimage. 37:1427-1436.
54. Straube T, Schmidt S, Weiss T, Mentzel H-J, Miltner WHR. 2009. Dynamic activation of the anterior cingulate cortex during anticipatory anxiety. Neuroimage. 44:975-981.
55. Vogt BA. 2005. Pain and emotion interactions in subregions of the cingulate gyrus. Nat Rev Neurosci. 6:533-544.
56. Wager TD, Rilling JK, Smith EE, Sokolik A, Casey KL, Davidson RJ, Kosslyn SM, Rose RM, Cohen JD. 2004. Placebo-induced changes in fMRI in the anticipation and experience of pain. Science. 303:1162-1167.
57. Watson D, Clark LA, Tellegen A. 1988. Development and validation of brief measures of positive and negative affect-the PANAS scales. J Pers Soc Psychol. 54:1063-1070.
58. Whalen PJ. 1998. Fear, vigilance, and ambiguity: initial neuroimaging studies of the human amygdala. Curr Dir Psychol Sci. 7:177-188.