Feeling anxious: Anticipatory amygdalo-insular response predicts the feeling of anxious anticipation

Social Cognitive and Affective Neuroscience

Volumn 6, Issue 1, 2011, Pages 74-81

  Carlson, Joshua M ^a   Greenberg, Tsafrir ^a   Rubin, Denis ^a   Mujica Parodi, Lilianne R ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

Amygdala; Anticipation; Anxiety; Auditory; Insula

Indexed keywords

OXYGEN;

ADOLESCENT; ADULT; AMYGDALOID NUCLEUS; ANXIETY; ARTICLE; ASSOCIATION; AUDITORY STIMULATION; BLOOD; BRAIN MAPPING; CINGULATE GYRUS; EMOTION; FEMALE; HUMAN; IMAGE PROCESSING; MALE; METHODOLOGY; MIDDLE AGED; NERVE TRACT; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PHOTOSTIMULATION; PHYSIOLOGY; TIME; VASCULARIZATION;

ACOUSTIC STIMULATION; ADOLESCENT; ADULT; AMYGDALA; ANXIETY; BRAIN MAPPING; CUES; EMOTIONS; FEMALE; GYRUS CINGULI; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEURAL PATHWAYS; OXYGEN; PHOTIC STIMULATION; TIME FACTORS; YOUNG ADULT;

EID: 78751681567     PISSN: 17495016     EISSN: 17495024     Source Type: Journal    
DOI: 10.1093/scan/nsq017     Document Type: Article

References (34)

1. Armony, J.L., Corbo, V., Clement, M.H., Brunet, A. (2005). Amygdala response in patients with acute PTSD to masked and unmasked emotional facial expressions. American Journal of Psychiatry, 162(10), 1961-3
2. Botvinick, M.M. (2007). Conflict monitoring and decision making: reconciling two perspectives on anterior cingulate function. Cognitive, Affective, and Behavioural Neuroscience, 7(4), 356-66.
3. Bryant, R.A., Kemp, A.H., Felmingham, K.L., Liddell, B., Olivieri, G., Peduto, A., et al. (2008). Enhanced amygdala and medial prefrontal activation during nonconscious processing of fear in posttraumatic stress disorder: an fMRI study. Human Brain Mapping, 29(5), 517-23.
4. Carlson, J.M., Reinke, K.S., Habib, R. (2009). A left amygdala mediated network for rapid orienting to masked fearful faces. Neuropsychologia, 47(5), 1386-9.
5. Craig, A.D. (2003). Interoception: the sense of the physiological condition of the body. Current Opinion on Neurobiology, 13(4), 500-5.
6. Critchley, H.D., Wiens, S., Rotshtein, P., Ohman, A., Dolan, R.J. (2004). Neural systems supporting interoceptive awareness. Nature Neuroscience, 7(2), 189-95.
7. Dalton, K.M., Kalin, N.H., Grist, T.M., Davidson, R.J. (2005). Neural-cardiac coupling in threat-evoked anxiety. Journal of Cognitive Neuroscience, 17(6), 969-80.
8. Davis, M., Whalen, P.J. (2001). The amygdala: vigilance and emotion. Molecular Psychiatry, 6(1), 13-34.
9. Etkin, A., Klemenhagen, K.C., Dudman, J.T., Rogan, M.T., Hen, R., Kandel, E.R., et al. (2004). Individual differences in trait anxiety predict the response of the basolateral amygdala to unconsciously processed fearful faces. Neuron, 44(6), 1043-55.
10. Knight, D.C., Nguyen, H.T., Bandettini, P.A. (2005). The role of the human amygdala in the production of conditioned fear responses. Neuroimage, 26(4), 1193-200.
11. LeDoux, J.E. (1996). The Emotional Brain the Mysterious Mnderpinnings of Emotional Life. London: Weidenfeld and Nicholson.
12. Lorberbaum, J.P., Kose, S., Johnson, M.R., Arana, G.W., Sullivan, L.K., Hamner, M.B., et al. (2004). Neural correlates of speech anticipatory anxiety in generalized social phobia. Neuroreport, 15(18), 2701-5.
13. Meyer, T.J., Miller, M.L., Metzger, R.L., Borkovec, T.D. (1990). Development and validation of the Penn State Worry Questionnaire. Behaviour Research and Therapy, 28, 487-95.
14. Morris, J.S., Frith, C.D., Perrett, D.I., Rowland, D., Young, A.W., Calder, A.J., et al. (1996). A differential neural response in the human amygdala to fearful and happy facial expressions. Nature, 383(6603), 812-5.
15. Morris, J.S., Ohman, A., Dolan, R.J. (1998). Conscious and unconscious emotional learning in the human amygdala. Nature, 393(6684), 467-70.
16. Nitschke, J.B., Sarinopoulos, I., Mackiewicz, K.L., Schaefer, H.S., Davidson, R.J. (2006). Functional neuroanatomy of aversion and its anticipation. Neuroimage, 29(1), 106-16.
17. Ochsner, K.N., Bunge, S.A., Gross, J.J., Gabrieli, J.D. (2002). Rethinking feelings: an FMRI study of the cognitive regulation of emotion. Journal of Cognitive Neuroscience, 14(8), 1215-29.
18. Onoda, K., Okamoto, Y., Toki, S., Ueda, K., Shishida, K., Kinoshita, A., et al. (2008). Anterior cingulate cortex modulates preparatory activation during certain anticipation of negative picture. Neuropsychologia, 46(1), 102-10.
19. Pasley, B.N., Mayes, L.C., Schultz, R.T. (2004). Subcortical discrimination of unperceived objects during binocular rivalry. Neuron, 42(1), 163-72
20. Phelps, E.A., O'Connor, K.J., Gatenby, J.C., Gore, J.C., Grillon, C., Davis, M. (2001). Activation of the left amygdala to a cognitive representation of fear. Nature Neuroscience, 4(4), 437-41.
21. Phillips, M.L., Young, A.W., Senior, C., Brammer, M., Andrew, C., Calder, A.J., et al. (1997). A specific neural substrate for perceiving facial expressions of disgust. Nature, 389(6650), 495-8.
22. Rauch, S.L., Whalen, P.J., Shin, L.M., McInerney, S.C., Macklin, M.L., Lasko, N.B., et al. (2000). Exaggerated amygdala response to masked facial stimuli in posttraumatic stress disorder: a functional MRI study. Biological Psychiatry, 47(9), 769-76.
23. Sallet, J., Quilodran, R., Rothe, M., Vezoli, J., Joseph, J.P., Procyk, E. (2007). Expectations, gains, and losses in the anterior cingulate cortex. Cognitive, Affective, and Behavioural Neuroscience, 7(4), 327-36.
24. Simmons, A., Matthews, S.C., Stein, M.B., Paulus, M.P. (2004). Anticipation of emotionally aversive visual stimuli activates right insula. Neuroreport, 15(14), 2261-5.
25. Simmons, A., Strigo, I., Matthews, S.C., Paulus, M.P., Stein, M.B. (2006). Anticipation of aversive visual stimuli is associated with increased insula activation in anxiety-prone subjects. Biological Psychiatry, 60(4), 402-9.
26. Simpson, J.R. Jr, Drevets, W.C., Snyder, A.Z., Gusnard, D.A., Raichle, M.E. (2001). Emotion-induced changes in human medial prefrontal cortex: II. During anticipatory anxiety. Proceedings of National Academy of Sciences USA, 98(2), 688-93.
27. Spielberger, C.D., Gorsuch, R.L., Lushene, R.E. (1970). Manual for the StateTrait Anxiety Inventory (Self-Evaluation Questionaire. Palo Alto, CA: Consulting Psychology Press.
28. Straube, T., Mentzel, H.J., Miltner, W.H. (2007). Waiting for spiders: brain activation during anticipatory anxiety in spider phobics. Neuroimage, 37(4), 1427-36.
29. Walter, B., Blecker, C., Kirsch, P., Sammer, G., Schienle, A., Stark, R., et al. (2003). MARINA: An easy to use tool for the creation of MAsks for Region of INterest Analyses. Paper presented at the Ninth International Conference on Functional Mapping of the Human Brain: NY, New York
30. Waugh, C.E., Wager, T.D., Fredrickson, B.L., Noll, D.C., Taylor, S.F. (2008). The neural correlates of trait resilience when anticipating and recovering from threat. Social Cognitive and Affective Neuroscience, 3(4), 322-32.
31. Whalen, P.J., Rauch, S.L., Etcoff, N.L., McInerney, S.C., Lee, M.B., Jenike, M.A. (1998). Masked presentations of emotional facial expressions modulate amygdala activity without explicit knowledge. Journal of Neuroscience, 18(1), 411-8.
32. Williams, M.A., Morris, A.P., McGlone, F., Abbott, D.F., Mattingley, J.B. (2004). Amygdala responses to fearful and happy facial expressions under conditions of binocular suppression. Journal of Neuroscience, 24(12), 2898-904.
33. Wright, P., He, G., Shapira, N.A., Goodman, W.K., Liu, Y. (2004). Disgust and the insula: fMRI responses to pictures of mutilation and contamination. Neuroreport, 15(15), 2347-51.
34. Zald, D.H. (2003). The human amygdala and the emotional evaluation of sensory stimuli. Brain Research. Brain Research Reviews, 41(1), 88-123.