Serum inflammatory markers and preeclampsia in type 1 diabetes: A prospective study

Diabetes Care

Volumn 36, Issue 7, 2013, Pages 2054-2061

  Du, Mei ^a   Basu, Arpita ^b   Fu, Dongxu ^a   Wu, Mingyuan ^a   Centola, Michael ^c   Jenkins, Alicia J ^a,d   Hanssen, Kristian F ^e   Garg, Satish K ^f   Hammad, Samar M ^g   Scardo, James A ^h   Aston, Christopher E ⁱ   Lyons, Timothy J ^a  

^a UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^b OKLAHOMA STATE UNIVERSITY   (United States)

^c OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

^d UNIVERSITY OF MELBOURNE   (Australia)

^e OSLO UNIVERSITY HOSPITAL   (Norway)

^f UNIVERSITY OF COLORADO DENVER   (United States)

^g MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^h Gibbs Cancer Center   (United States)

ⁱ UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; EOTAXIN; GAMMA INTERFERON INDUCIBLE PROTEIN 10; HEMOGLOBIN A1C; INFLAMMATORY MARKER; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 12; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MONOCYTE CHEMOTACTIC PROTEIN 1; PADGEM PROTEIN; RANTES; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ADULT; ARTICLE; BLOOD SAMPLING; BODY MASS; CONTROLLED STUDY; DISEASE DURATION; FEMALE; FIRST TRIMESTER PREGNANCY; HEMOGLOBIN BLOOD LEVEL; HUMAN; INFLAMMATION; INSULIN DEPENDENT DIABETES MELLITUS; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MATERNAL BLOOD; MEAN ARTERIAL PRESSURE; ONSET AGE; PATHOPHYSIOLOGY; PREECLAMPSIA; PREGNANT WOMAN; PREVALENCE; PROSPECTIVE STUDY; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; SECOND TRIMESTER PREGNANCY; THIRD TRIMESTER PREGNANCY;

C-REACTIVE PROTEIN; CHEMOKINE CXCL10; DIABETES MELLITUS, TYPE 1; E-SELECTIN; FEMALE; HUMANS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; LONGITUDINAL STUDIES; PRE-ECLAMPSIA; PREGNANCY; PROSPECTIVE STUDIES;

EID: 84880209092     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc12-1934     Document Type: Article

References (39)

1. Manten GT, Sikkema MJ, Voorbij HA, Visser GH, Bruinse HW, Franx A. Risk factors for cardiovascular disease in women with a history of pregnancy complicated by preeclampsia or intrauterine growth restriction. Hypertens Pregnancy 2007;26: 39-50
2. Redman CW, Sacks GP, Sargent IL. Preeclampsia: an excessive maternal inflammatory response to pregnancy. Am J Obstet Gynecol 1999;180:499-506
3. de Jonge LL, Steegers EA, Ernst GD., et al. C-reactive protein levels, blood pressure and the risks of gestational hypertensive complications: the Generation R Study. J Hypertens 2011;29: 2413-2421
4. Forest JC, Charland M, Massé J., et al. Candidate biochemical markers for screening of pre-eclampsia in early pregnancy. Clin Chem Lab Med 2012; 50:973-984
5. Ertas IE, Kahyaoglu S, Yilmaz B., et al. Association of maternal serum high sensitive C-reactive protein level with body mass index and severity of pre-eclampsia at third trimester. J Obstet Gynaecol Res 2010;36:970-977
6. Molvarec A, Szarka A, Walentin S., et al. Serum leptin levels in relation to circulating cytokines, chemokines, adhesion molecules and angiogenic factors in normal pregnancy and preeclampsia. Reprod Biol Endocrinol 2011;9:124
7. Cemgil Arikan D, Aral M, Coskun A, Ozer A. Plasma IL-4, IL-8, IL-12, interferon-g and CRP levels in pregnant women with preeclampsia, and their relation with severity of disease and fetal birth weight. J Matern Fetal Neonatal Med 2012;25: 1569-1573
8. Montagnana M, Lippi G, Albiero A, Salvagno GL, Franchi M, Guidi GC. Serum pro-inflammatory cytokines in physiological and pre-eclamptic pregnancies. Gynecol Endocrinol 2008;24: 113-116
9. Jonsson Y, Rubèr M, Matthiesen L., et al. Cytokine mapping of sera from women with preeclampsia and normal pregnancies. J Reprod Immunol 2006;70: 83-91
10. Carty DM, Anderson LA, Freeman DJ., et al. Early pregnancy soluble E-selectin concentrations and risk of preeclampsia. J Hypertens 2012;30:954-959
11. Clausen T, Djurovic S, Brosstad FR, Berg K, Henriksen T. Altered circulating levels of adhesion molecules at 18 weeks' gestation among women with eventual preeclampsia: indicators of disturbed placentation in absence of evidence of endothelial dysfunction? Am J Obstet Gynecol 2000;182:321-325
12. Kronborg CS, Gjedsted J, Vittinghus E, Hansen TK, Allen J, Knudsen UB. Longitudinal measurement of cytokines in pre-eclamptic and normotensive pregnancies. Acta Obstet Gynecol Scand 2011; 90:791-796
13. Clausen P, Ekbom P, Damm P., et al. Signs of maternal vascular dysfunction precede preeclampsia in women with type 1 diabetes. J Diabetes Complications 2007;21: 288-293
14. Yu Y, Jenkins AJ, Nankervis AJ., et al. Antiangiogenic factors and pre-eclampsia in type 1 diabetic women. Diabetologia 2009; 52:160-168
15. Azar M, Basu A, Jenkins AJ., et al. Serum carotenoids and fat-soluble vitamins in women with type 1 diabetes and preeclampsia: a longitudinal study. Diabetes Care 2011;34:1258-1264
16. Basu A, Alaupovic P, Wu M., et al. Plasma lipoproteins and preeclampsia in women with type 1 diabetes: a prospective study. J Clin Endocrinol Metab 2012;97:1752-1762
17. Jenkins AJ, Rothen M, Klein RL., et al.; DCCT/EDIC Research Group. Crosssectional associations of C-reactive protein with vascular risk factors and vascular complications in the DCCT/EDIC cohort. J Diabetes Complications 2008;22:153-163
18. Alex P, Szodoray P, Knowlton N., et al. Multiplex serum cytokine monitoring as a prognostic tool in rheumatoid arthritis. Clin Exp Rheumatol 2007;25: 584-592
19. Ridker PM, Cushman M, Stampfer MJ, Tracy RP, Hennekens CH. Plasma concentration of C-reactive protein and risk of developing peripheral vascular disease. Circulation 1998;97:425-428
20. Emerging Risk Factors Collaboration; Kaptoge S, Di Angelantonio E, Pennells L., et al. C-reactive protein, fibrinogen, and cardiovascular disease prediction. N Engl J Med 2012;367:1310-1320
21. Sesso HD, Buring JE, Rifai N, Blake GJ, Gaziano JM, Ridker PM. C-reactive protein and the risk of developing hypertension. JAMA 2003;290:2945-2951
22. Wolf M, Kettyle E, Sandler L, Ecker JL, Roberts J, Thadhani R. Obesity and preeclampsia: the potential role of inflammation. Obstet Gynecol 2001;98: 757-762
23. Qiu C, Luthy DA, Zhang C, Walsh SW, Leisenring WM, Williams MA. A prospective study of maternal serumC-reactive protein concentrations and risk of preeclampsia. Am J Hypertens 2004;17:154-160
24. Loukovaara S, Immonen I, Koistinen R, Hiilesmaa V, Kaaja R. Inflammatory markers and retinopathy in pregnancies complicated with type I diabetes. Eye (Lond) 2005;19:422-430
25. Li H, Cybulsky MI, Gimbrone MA Jr, Libby P. Inducible expression of vascular cell adhesion molecule-1 by vascular smooth muscle cells in vitro and within rabbit atheroma. Am J Pathol 1993;143: 1551-1559
26. Price DT, Loscalzo J. Cellular adhesion molecules and atherogenesis. Am J Med 1999;107:85-97
27. Clausen P, Jacobsen P, Rossing K, Jensen JS, Parving HH, Feldt-Rasmussen B. Plasma concentrations of VCAM-1 and ICAM-1 are elevated in patients with Type 1 diabetes mellitus with microalbuminuriaand overt nephropathy. Diabet Med 2000; 17:644-649
28. Schram MT, Chaturvedi N, Schalkwijk C., et al.; EURODIAB Prospective Complications Study. Vascular risk factors and markers of endothelial function as determinants of inflammatory markers in type 1 diabetes: the EURODIAB Prospective Complications Study. Diabetes Care 2003; 26:2165-2173
29. Gibson JL, Lyall F, Boswell F, Young A, Maccuish AC, Greer IA. Circulating cell adhesion molecule concentrations in diabetic women during pregnancy. Obstet Gynecol 1997;90:874-879
30. Ait-Oufella H, Taleb S,Mallat Z, Tedgui A. Recent advances on the role of cytokines in atherosclerosis. Arterioscler Thromb Vasc Biol 2011;31:969-979
31. Wegmann TG, Lin H, Guilbert L, Mosmann TR. Bidirectional cytokine interactions in the maternal-fetal relationship: is successful pregnancy a TH2 phenomenon? Immunol Today 1993;14: 353-356
32. Vince GS, Starkey PM, Austgulen R, Kwiatkowski D, RedmanCW. Interleukin-6, tumour necrosis factor and soluble tumour necrosis factor receptors in women with preeclampsia. Br J Obstet Gynaecol 1995;102: 20-25
33. Pfleger C, Mortensen HB, Hansen L., et al.; Hvidøre Study Group on Childhood Diabetes. Association of IL-1ra and adiponectin with C-peptide and remission in patients with type 1 diabetes. Diabetes 2008;57:929-937
34. Greer IA, Lyall F, Perera T, Boswell F, Macara LM. Increased concentrations of cytokines interleukin-6 and interleukin-1 receptor antagonist in plasma of women with preeclampsia: a mechanism for endothelial dysfunction? Obstet Gynecol 1994;84:937-940
35. Szarka A, Rigó J Jr, Lázár L, Beko G, Molvarec A. Circulating cytokines, chemokines and adhesion molecules in normal pregnancy and preeclampsia determined by multiplex suspension array. BMC Immunol 2010;11:59
36. Shimada A, Morimoto J, Kodama K., et al. Elevated serum IP-10 levels observed in type 1 diabetes. Diabetes Care 2001;24: 510-515
37. Ramsay JE, Simms RJ, Ferrell WR., et al. Enhancement of endothelial function by pregnancy: inadequate response in women with type 1 diabetes. Diabetes Care 2003; 26:475-479
38. Thavasu PW, Longhurst S, Joel SP, Slevin ML, Balkwill FR. Measuring cytokine levels in blood. Importance of anticoagulants, processing, and storage conditions. J Immunol Methods 1992;153:115-124
39. Kraus TA, Sperling RS, Engel SM., et al. Peripheral blood cytokine profiling during pregnancy and post-partum periods. Am J Reprod Immunol 2010;64: 411-426