Serum pro-inflammatory cytokines in physiological and pre-eclamptic pregnancies

Gynecological Endocrinology

Volumn 24, Issue 3, 2008, Pages 113-116

  Montagnana, Martina ^a,b   Lippi, Giuseppe ^a   Albiero, Alessandro ^a   Salvagno, Gian Luca ^a   Franchi, Massimo ^a   Guidi, Gian Cesare ^a  

^a UNIVERSITY OF VERONA   (Italy)

^b UNIVERSITY HOSPITAL OF VERONA   (Italy)

Author keywords

Cytokines; Hypertension; Inflammation; Pre eclampsia; Pregnancy

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 1; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FIRST TRIMESTER PREGNANCY; HUMAN; INFLAMMATION; PHYSIOLOGY; PREECLAMPSIA; PREGNANT WOMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SCREENING; SECOND TRIMESTER PREGNANCY; STATISTICAL SIGNIFICANCE; THIRD TRIMESTER PREGNANCY;

CYTOKINES; FEMALE; GESTATIONAL AGE; HUMANS; INFLAMMATION; INTERFERON TYPE II; INTERLEUKIN-1; INTERLEUKIN-6; PRE-ECLAMPSIA; PREGNANCY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 40549113659     PISSN: 09513590     EISSN: 14730766     Source Type: Journal    
DOI: 10.1080/09513590801895575     Document Type: Article

References (15)

1. Lain KY, Roberts JM. Contemporary concepts of the pathogenesis and management of preeclampsia. JAMA 2002;287:3183-3186.
2. Borzychowski AM, Sargent IL, Redman CW. Inflammation and pre-eclampsia. Semin Fetal Neonatal Med 2006;11:309-316.
3. Jonsson Y, Ruber M, Matthiesen L, Berg G, Nieminen K, Sharma S, Ernerudh J, Ekerfelt C. Cytokine mapping of sera from women with preeclampsia and normal pregnancies. J Reprod Immunol 2006;70:83-91.
4. Akira S, Taga T, Kishimoto T. Interleukin-6 in biology and medicine. Adv Immunol 1993;54:1-78.
5. Hung TH, Charnock-Jones DS, Skepper JN, Burton GJ. Secretion of tumor necrosis factor-a from human placental tissues induced by hypoxia-reoxygenation causes endothelial cell activation in vitro: a potential mediator of the inflammatory response in preeclampsia. Am J Pathol 2004;164:1049-1061.
6. Alexander BT, Cockrell KL, Massey MB, Bennett WA, Granger JP. Tumor necrosis factor-α-induced hypertension in pregnant rats results in decreased renal neuronal nitric oxide synthase expression. Am J Hypertens 2002;15:170-175.
7. Lee SA, Fitzgerald SM, Huang SK, Li C, Chi DS, Krishnaswamy G. Molecular regulation of IL-13 and MCP-1 expression in human mast cells by IL-1β. Am J Respir Cell Mol Biol 2004;31:283-291.
8. Hefler LA, Tempfer CB, Gregg AR. Polymorphisms within the interleukin-1β gene cluster and preeclampsia. Obstet Gynecol 2001;97:664-668.
9. Lok CA, Boing AN, Reitsma PH, van der Post JA, van Bavel E, Boer K, Sturk A, Nieuwland R. Expression of inflammation-related genes in endothelial cells is not directly affected by microparticles from preeclamptic patients. J Lab Clin Med 2006;147:310-320.
10. Ostensen M, Forger F, Villiger PM. Cytokines and pregnancy in rheumatic disease. Ann N Y Acad Sci 2006;1069:353-363.
11. Veith GL, Rice GE. Interferon γ expression during human pregnancy and in association of labour. Gynecol Obstet Invest 1999;48:163-167.
12. Russwurm GP, Mackler AM, Fagoaga OR, Brown WS, Sakala EP, Yellon SM, Nehlsen-Cannarella SL. Soluble human leukocyte antigens, interleukin-6, and interferon-γ during pregnancy. Am J Reprod Immunol 1997;38:256-262.
13. Roberts JM, Lain KY. Recent insights into the pathogenesis of pre-eclampsia. Placenta 2002;23:359-372.
14. Austgulen R, Lien E, Liabakk NB, Jacobsen G, Arntzen KJ. Increased levels of cytokines and cytokine activity modifiers in normal pregnancy. Eur J Obstet Gynecol Reprod Biol 1994;57:149-155.
15. Conrad KP, Miles TM, Benyo DF. Circulating levels of immunoreactive cytokines in women with preeclampsia. Am J Reprod Immunol 1998;40:102-111.