Perturbations in skeletal muscle sarcomere structure in patients with heart failure and type 2 diabetes: Restorative effects of (-)-epicatechinrich cocoa

Clinical Science

Volumn 125, Issue 8, 2013, Pages 383-389

  Taub, Pam R ^a   Ramirez Sanchez, Israel ^a,b   Ciaraldi, Theodore P ^a,c   Gonzalez Basurto, Silvia ^b   Coral Vazquez, Ramon ^b   Perkins, Guy ^a   Hogan, Michael ^a   Maisel, Alan S ^a,c   Henry, Robert R ^a,c   Ceballos, Guillermo ^b   Villarreal, Francisco ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b INSTITUTO POLITÉCNICO NACIONAL   (Mexico)

^c VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

Atrophy; Dystrophin; Mitochondrion; Myofibre; Skeletal muscle; Type 2 diabetes

Indexed keywords

DYSTROPHIN ASSOCIATED PROTEIN COMPLEX; EPICATECHIN; OXYGEN;

ADULT; AGED; ARTICLE; CACAO; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ELECTRON MICROSCOPY; HEART FAILURE; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; MITOCHONDRION; MUSCLE BIOPSY; MUSCLE CELL; MUSCLE GROWTH; NON INSULIN DEPENDENT DIABETES MELLITUS; OXYGEN CONSUMPTION; PHYSICAL ACTIVITY; PILOT STUDY; PRIORITY JOURNAL; SARCOMERE; SKELETAL MUSCLE; TREADMILL EXERCISE; WESTERN BLOTTING;

AGED; BLOTTING, WESTERN; CACAO; CATECHIN; DIABETES MELLITUS, TYPE 2; DYSTROPHIN; DYSTROPHIN-ASSOCIATED PROTEIN COMPLEX; EXERCISE TEST; HEART FAILURE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MEMBRANE PROTEINS; MICROSCOPY, ELECTRON, TRANSMISSION; MIDDLE AGED; MUSCLE PROTEINS; MUSCLE, SKELETAL; PILOT PROJECTS; SARCOGLYCANS; SARCOMERES; TREATMENT OUTCOME; UTROPHIN;

EID: 84880175168     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20130023     Document Type: Article

References (24)

1. Conraads, V. M., Hoymans, V. Y. and Vrints, C. J. (2008) Heart failure and cachexia: insights offered from molecular biology. Front. Biosci. 13, 325-335
2. Drexler, H., Riede, U., Munzel, T., Konig, H., Funke, E. and Just, H. (1992) Alterations of skeletal muscle in chronic heart failure. Circulation 85, 1751-1759
3. Miller, M. S., Vanburen, P., Lewinter, M. M., Lecker, S. H., Selby, D. E., Palmer, B. M., Maughan, D. W., Ades, P. A. and Toth, M. J. (2009) Mechanisms underlying skeletal muscle weakness in human heart failure: alterations in single fiber myosin protein content and function. Circ. Heart Failure 2, 700-706
4. Chomentowski, P., Coen, P. M., Radikova, Z., Goodpaster, B. H. and Toledo, F. G. (2011) Skeletal muscle mitochondria in insulin resistance: differences in intermyofibrillar versus subsarcolemmal subpopulations and relationship to metabolic flexibility. J. Clin. Endocrinol. Metab. 96, 494-503
5. Nielsen, J., Mogensen, M., Vind, B. F., Sahlin, K., Hojlund, K., Schroder, H. D. and Ortenblad, N. (2010) Increased subsarcolemmal lipids in type 2 diabetes: effect of training on localization of lipids, mitochondria, and glycogen in sedentary human skeletal muscle. Am. J. Physiol. Endocrinol. Metab. 298, E706-E713
6. Mulvey, C., Mullen, E. and Ohlendieck, K. (2008) The pathobiochemical role of the dystrophin-dystroglycan complex and the Ca2+ -handling apparatus in diabetes-related muscle weakness. Mol. Med. Rep. 1, 297-306
7. Durbeej, M. and Campbell, K. P. (2002) Muscular dystrophies involving the dystrophin-glycoprotein complex: an overview of current mouse models. Curr. Opin. Genet. Dev. 12, 349-361
8. Vatta, M., Stetson, S. J., Perez-Verdia, A., Entman, M. L., Noon, G. P., Torre-Amione, G., Bowles, N. E. and Towbin, J. A. (2002) Molecular remodelling of dystrophin in patients with end-stage cardiomyopathies and reversal in patients on assistance-device therapy. Lancet 359, 936-941
9. Keteyian, S. J., Fleg, J. L., Brawner, C. A. and Pina, I. L. (2010) Role and benefits of exercise in the management of patients with heart failure. Heart Fail. Rev. 15, 523-530
10. Praet, S. F. and van Loon, L. J. (2007) Optimizing the therapeutic benefits of exercise in Type 2 diabetes. J. Appl. Physiol. 103, 1113-1120
11. Nogueira, L., Ramirez-Sanchez, I., Perkins, G. A., Murphy, A., Taub, P. R., Ceballos, G., Villarreal, F. J., Hogan, M. C. and Malek, M. H. (2011) (-)-Epicatechin enhances fatigue resistance and oxidative capacity in mouse muscle. J. Physiol. 589, 4615-4631
12. Taub, P., Ramirez-Sanchez, I., Ciaraldi, T., Perkins, G., Murphy, A., Naviaux, R., Hogan, M., Ceballos, G., Maisel, A., Henry, R. et al. (2012) Alterations in skeletal muscle indicators of mitochondrial structure and biogenesis in patients with type 2 diabetes and heart failure: effects of epicatechin rich cocoa. Clin. Transl. Sci. 5, 43-47
13. Wagatsuma, A., Kotake, N. and Yamada, S. (2010) Muscle regeneration occurs to coincide with mitochondrial biogenesis. Mol. Cell. Biochem. 349, 139-147
14. Rodino-Klapac, L. R., Haidet, A. M., Kota, J., Handy, C., Kaspar, B. K. and Mendell, J. R. (2009) Inhibition of myostatin with emphasis on follistatin as a therapy for muscle disease. Muscle Nerve 39, 283-296
15. Glover, L. and Brown, Jr, R. H. (2007) Dysferlin in membrane trafficking and patch repair. Traffic 8, 785-794
16. Mok, G. F. and Sweetman, D. (2011) Many routes to the same destination: lessons from skeletal muscle development. Reproduction 141, 301-312
17. Working Group Report (2001) Recommendations for exercise testing in chronic heart failure patients. Eur. Heart J. 22, 37-45
18. Acharyya, S., Butchbach, M. E., Sahenk, Z., Wang, H., Saji, M., Carathers, M., Ringel, M. D., Skipworth, R. J., Fearon, K. C., Hollingsworth, M. A. et al. (2005) Dystrophin glycoprotein complex dysfunction: a regulatory link between muscular dystrophy and cancer cachexia. Cancer Cell 8, 421-432
19. Mulvey, C., Harno, E., Keenan, A. and Ohlendieck, K. (2005) Expression of the skeletal muscle dystrophin-dystroglycan complex and syntrophin-nitric oxide synthase complex is severely affected in the type 2 diabetic Goto-Kakizaki rat. Eur. J. Cell Biol. 84, 867-883
20. Leiter, J. R., Upadhaya, R. and Anderson, J. E. (2012) Nitric oxide and voluntary exercise together promote quadriceps hypertrophy and increase vascular density in female 18-month-old mice. Am. J. Physiol. Cell Physiol. 302, C1306-C1315
21. Buitrago-Lopez, A., Sanderson, J., Johnson, L., Warnakula, S., Wood, A., Di Angelantonio, E. and Franco, O. H. (2011) Chocolate consumption and cardiometabolic disorders: systematic review and meta-analysis. BMJ 343, d4488
22. Corti, R., Flammer, A. J., Hollenberg, N. K. and Luscher, T. F. (2009) Cocoa and cardiovascular health. Circulation 119, 1433-1441
23. Yamazaki, K. G., Taub, P. R., Barraza-Hidalgo, M., Rivas, M. M., Zambon, A. C., Ceballos, G. and Villarreal, F. J. (2010) Effects of (-)-epicatechin on myocardial infarct size and left ventricular remodeling after permanent coronary occlusion. J. Am. Coll. Cardiol. 55, 2869-2876
24. Lenk, K., Erbs, S., Hollriege, R., Beck, E., Linke, A., Gielen, S., Mobius Winkler, S., Sandri, M., Hambrecht, R., Schuler, G. et al. (2011) Exercise training leads to a reduction of elevated myostatin levels in patients with chronic heart failure. Eur. J. Cardiovasc. Prev. Rehabil. 19, 404-411