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Volumn 55, Issue 8, 2013, Pages 689-697

The potential for stem cell therapies to have an impact on cerebral palsy: Opportunities and limitations

Author keywords

[No Author keywords available]

Indexed keywords

CELL DIFFERENTIATION; CELL TYPE; CEREBRAL PALSY; CLINICAL TRIAL (TOPIC); EMBRYONIC STEM CELL; GRAFT SURVIVAL; HUMAN; IN VIVO STUDY; MESENCHYMAL STEM CELL; MULTIPOTENT STEM CELL; NERVE DEGENERATION; NEURAL STEM CELL; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; REVIEW; STEM CELL TRANSPLANTATION; TOTIPOTENT STEM CELL;

EID: 84880156565     PISSN: 00121622     EISSN: 14698749     Source Type: Journal    
DOI: 10.1111/dmcn.12166     Document Type: Review
Times cited : (35)

References (53)
  • 2
    • 0032488370 scopus 로고    scopus 로고
    • Intrapartum risk factors for newborn encephalopathy: the Western Australian case-control study
    • Badawi N, Kurinczuk JJ, Keogh JM, et al. Intrapartum risk factors for newborn encephalopathy: the Western Australian case-control study. BMJ 1998; 317: 1554-8.
    • (1998) BMJ , vol.317 , pp. 1554-1558
    • Badawi, N.1    Kurinczuk, J.J.2    Keogh, J.M.3
  • 3
    • 33846939837 scopus 로고    scopus 로고
    • No improvement in outcome of nationwide extremely low birth weight infant populations between 1996-1997 and 1999-2000
    • Tommiska V, Heinonen K, Lehtonen L, et al. No improvement in outcome of nationwide extremely low birth weight infant populations between 1996-1997 and 1999-2000. Pediatrics 2007; 119: 29-36.
    • (2007) Pediatrics , vol.119 , pp. 29-36
    • Tommiska, V.1    Heinonen, K.2    Lehtonen, L.3
  • 4
    • 57149118216 scopus 로고    scopus 로고
    • Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances
    • Volpe JJ. Brain injury in premature infants: a complex amalgam of destructive and developmental disturbances. Lancet Neurol 2009; 8: 110-24.
    • (2009) Lancet Neurol , vol.8 , pp. 110-124
    • Volpe, J.J.1
  • 5
    • 69249224791 scopus 로고    scopus 로고
    • The relationship of cerebral palsy subtype and functional motor impairment: a population-based study
    • Shevell MI, Dagenais L, Hall N. The relationship of cerebral palsy subtype and functional motor impairment: a population-based study. Dev Med Child Neurol 2009; 51: 872-7.
    • (2009) Dev Med Child Neurol , vol.51 , pp. 872-877
    • Shevell, M.I.1    Dagenais, L.2    Hall, N.3
  • 6
    • 33846424598 scopus 로고    scopus 로고
    • Hypoxia-ischemia preferentially triggers glutamate depletion from oligodendroglia and axons in perinatal cerebral white matter
    • Back SA, Craig A, Kayton RJ, et al. Hypoxia-ischemia preferentially triggers glutamate depletion from oligodendroglia and axons in perinatal cerebral white matter. J Cereb Blood Flow Metab 2007; 27: 334-47.
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 334-347
    • Back, S.A.1    Craig, A.2    Kayton, R.J.3
  • 7
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K, Tanabe K, Ohnuki M, et al. Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 2007; 131: 861-72.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3
  • 8
    • 84857136772 scopus 로고    scopus 로고
    • Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells
    • Lujan E, Chanda S, Ahlenius H, Sudhof TC, Wernig M. Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells. Proc Natl Acad Sci USA 2012; 109: 2527-32.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 2527-2532
    • Lujan, E.1    Chanda, S.2    Ahlenius, H.3    Sudhof, T.C.4    Wernig, M.5
  • 9
    • 77955457938 scopus 로고    scopus 로고
    • Neural stem cells in regenerative medicine: bridging the gap
    • Ruff CA, Fehlings MG. Neural stem cells in regenerative medicine: bridging the gap. Panminerva Med 2010; 52: 125-47.
    • (2010) Panminerva Med , vol.52 , pp. 125-147
    • Ruff, C.A.1    Fehlings, M.G.2
  • 10
    • 84859905286 scopus 로고    scopus 로고
    • Cell-based transplantation strategies to promote plasticity following spinal cord injury
    • Ruff CA, Wilcox JT, Fehlings MG. Cell-based transplantation strategies to promote plasticity following spinal cord injury. Exp Neurol 2012; 235: 78-90.
    • (2012) Exp Neurol , vol.235 , pp. 78-90
    • Ruff, C.A.1    Wilcox, J.T.2    Fehlings, M.G.3
  • 11
    • 84872696866 scopus 로고    scopus 로고
    • Generation of neural stem cells from embryonic stem cells using the default mechanism: in vitro and in vivo characterization
    • Rowland JW, Lee JJ, Salewski RP, Eftekharpour E, van der Kooy D, Fehlings MG. Generation of neural stem cells from embryonic stem cells using the default mechanism: in vitro and in vivo characterization. Stem Cells Dev 2011; 20: 1829-45.
    • (2011) Stem Cells Dev , vol.20 , pp. 1829-1845
    • Rowland, J.W.1    Lee, J.J.2    Salewski, R.P.3    Eftekharpour, E.4    van der Kooy, D.5    Fehlings, M.G.6
  • 12
    • 77956633377 scopus 로고    scopus 로고
    • CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination
    • Zawadzka M, Rivers LE, Fancy SP, et al. CNS-resident glial progenitor/stem cells produce Schwann cells as well as oligodendrocytes during repair of CNS demyelination. Cell Stem Cell 2010; 6: 578-90.
    • (2010) Cell Stem Cell , vol.6 , pp. 578-590
    • Zawadzka, M.1    Rivers, L.E.2    Fancy, S.P.3
  • 13
    • 77649102445 scopus 로고    scopus 로고
    • Cyclosporin A has direct effects on adult neural precursor cells
    • Hunt J, Cheng A, Hoyles A, Jervis E, Morshead CM. Cyclosporin A has direct effects on adult neural precursor cells. J Neurosci 2010; 30: 2888-96.
    • (2010) J Neurosci , vol.30 , pp. 2888-2896
    • Hunt, J.1    Cheng, A.2    Hoyles, A.3    Jervis, E.4    Morshead, C.M.5
  • 14
    • 79952522631 scopus 로고    scopus 로고
    • Long-term magnetic resonance imaging of stem cells in neonatal ischemic injury
    • Obenaus A, Dilmac N, Tone B, et al. Long-term magnetic resonance imaging of stem cells in neonatal ischemic injury. Ann Neurol 2011; 69: 282-91.
    • (2011) Ann Neurol , vol.69 , pp. 282-291
    • Obenaus, A.1    Dilmac, N.2    Tone, B.3
  • 15
    • 76149105178 scopus 로고    scopus 로고
    • Synergistic effects of transplanted adult neural stem/progenitor cells, chondroitinase, and growth factors promote functional repair and plasticity of the chronically injured spinal cord
    • Karimi-Abdolrezaee S, Eftekharpour E, Wang J, Schut D, Fehlings MG. Synergistic effects of transplanted adult neural stem/progenitor cells, chondroitinase, and growth factors promote functional repair and plasticity of the chronically injured spinal cord. J Neurosci 2010; 30: 1657-76.
    • (2010) J Neurosci , vol.30 , pp. 1657-1676
    • Karimi-Abdolrezaee, S.1    Eftekharpour, E.2    Wang, J.3    Schut, D.4    Fehlings, M.G.5
  • 16
    • 0030779992 scopus 로고    scopus 로고
    • Use of Schwann cells to induce repair of adult CNS tracts
    • Raisman G. Use of Schwann cells to induce repair of adult CNS tracts. Rev Neurol (Paris) 1997; 153: 521-5.
    • (1997) Rev Neurol (Paris) , vol.153 , pp. 521-525
    • Raisman, G.1
  • 17
    • 4644275620 scopus 로고    scopus 로고
    • Transplantation of Schwann cells and olfactory ensheathing glia after spinal cord injury: does pretreatment with methylprednisolone and interleukin-10 enhance recovery?
    • Pearse DD, Marcillo AE, Oudega M, Lynch MP, Wood PM, Bunge MB. Transplantation of Schwann cells and olfactory ensheathing glia after spinal cord injury: does pretreatment with methylprednisolone and interleukin-10 enhance recovery? J Neurotrauma 2004; 21: 1223-39.
    • (2004) J Neurotrauma , vol.21 , pp. 1223-1239
    • Pearse, D.D.1    Marcillo, A.E.2    Oudega, M.3    Lynch, M.P.4    Wood, P.M.5    Bunge, M.B.6
  • 18
    • 35649017602 scopus 로고    scopus 로고
    • Neuronal populations capable of regeneration following a combined treatment in rats with spinal cord transection
    • Vavrek R, Pearse DD, Fouad K. Neuronal populations capable of regeneration following a combined treatment in rats with spinal cord transection. J Neurotrauma 2007; 24: 1667-73.
    • (2007) J Neurotrauma , vol.24 , pp. 1667-1673
    • Vavrek, R.1    Pearse, D.D.2    Fouad, K.3
  • 19
    • 34250192272 scopus 로고    scopus 로고
    • Transplantation of Schwann cells and/or olfactory ensheathing glia into the contused spinal cord: survival, migration, axon association, and functional recovery
    • Pearse DD, Sanchez AR, Pereira FC, et al. Transplantation of Schwann cells and/or olfactory ensheathing glia into the contused spinal cord: survival, migration, axon association, and functional recovery. Glia 2007; 55: 976-1000.
    • (2007) Glia , vol.55 , pp. 976-1000
    • Pearse, D.D.1    Sanchez, A.R.2    Pereira, F.C.3
  • 20
    • 79960832807 scopus 로고    scopus 로고
    • A systematic review of cellular transplantation therapies for spinal cord injury
    • Tetzlaff W, Okon EB, Karimi-Abdolrezaee S, et al. A systematic review of cellular transplantation therapies for spinal cord injury. J Neurotrauma 2011; 28: 1611-82.
    • (2011) J Neurotrauma , vol.28 , pp. 1611-1682
    • Tetzlaff, W.1    Okon, E.B.2    Karimi-Abdolrezaee, S.3
  • 21
    • 77951041837 scopus 로고    scopus 로고
    • Hematopoietic stem cell transplantation for osteopetrosis
    • Steward CG. Hematopoietic stem cell transplantation for osteopetrosis. Pediatr Clin North Am 2010; 57: 171-80.
    • (2010) Pediatr Clin North Am , vol.57 , pp. 171-180
    • Steward, C.G.1
  • 22
    • 33744459737 scopus 로고    scopus 로고
    • Strategies for widening the use of cord blood in hematopoietic stem cell transplantation
    • de Lima M, Shpall E. Strategies for widening the use of cord blood in hematopoietic stem cell transplantation. Haematologica 2006; 91: 584-7.
    • (2006) Haematologica , vol.91 , pp. 584-587
    • de Lima, M.1    Shpall, E.2
  • 23
    • 0036371435 scopus 로고    scopus 로고
    • Development of allogeneic hematopoietic stem cell transplantation (HSCT)
    • Castro JE, Ball ED. Development of allogeneic hematopoietic stem cell transplantation (HSCT). Cancer Treat Res 2002; 110: 1-37.
    • (2002) Cancer Treat Res , vol.110 , pp. 1-37
    • Castro, J.E.1    Ball, E.D.2
  • 24
    • 72449122797 scopus 로고    scopus 로고
    • BDNF-hypersecreting human mesenchymal stem cells promote functional recovery, axonal sprouting, and protection of corticospinal neurons after spinal cord injury
    • Sasaki M, Radtke C, Tan AM, et al. BDNF-hypersecreting human mesenchymal stem cells promote functional recovery, axonal sprouting, and protection of corticospinal neurons after spinal cord injury. J Neurosci 2009; 29: 14932-41.
    • (2009) J Neurosci , vol.29 , pp. 14932-14941
    • Sasaki, M.1    Radtke, C.2    Tan, A.M.3
  • 25
    • 69349089354 scopus 로고    scopus 로고
    • Delayed intralesional transplantation of bone marrow stromal cells increases endogenous neurogenesis and promotes functional recovery after severe traumatic brain injury
    • Bonilla C, Zurita M, Otero L, Aguayo C, Vaquero J. Delayed intralesional transplantation of bone marrow stromal cells increases endogenous neurogenesis and promotes functional recovery after severe traumatic brain injury. Brain Inj 2009; 23: 760-9.
    • (2009) Brain Inj , vol.23 , pp. 760-769
    • Bonilla, C.1    Zurita, M.2    Otero, L.3    Aguayo, C.4    Vaquero, J.5
  • 26
    • 68349160764 scopus 로고    scopus 로고
    • Therapeutic benefit of human umbilical cord derived mesenchymal stromal cells in intracerebral hemorrhage rat: implications of anti-inflammation and angiogenesis
    • Liao W, Zhong J, Yu J, et al. Therapeutic benefit of human umbilical cord derived mesenchymal stromal cells in intracerebral hemorrhage rat: implications of anti-inflammation and angiogenesis. Cell Physiol Biochem 2009; 24: 307-16.
    • (2009) Cell Physiol Biochem , vol.24 , pp. 307-316
    • Liao, W.1    Zhong, J.2    Yu, J.3
  • 27
    • 5044220530 scopus 로고    scopus 로고
    • Bone marrow transplants provide tissue protection and directional guidance for axons after contusive spinal cord injury in rats
    • Ankeny DP, McTigue DM, Jakeman LB. Bone marrow transplants provide tissue protection and directional guidance for axons after contusive spinal cord injury in rats. Exp Neurol 2004; 190: 17-31.
    • (2004) Exp Neurol , vol.190 , pp. 17-31
    • Ankeny, D.P.1    McTigue, D.M.2    Jakeman, L.B.3
  • 28
    • 4744341332 scopus 로고    scopus 로고
    • Infusion of human umbilical cord blood cells in a rat model of stroke dose-dependently rescues behavioral deficits and reduces infarct volume
    • Vendrame M, Cassady J, Newcomb J, et al. Infusion of human umbilical cord blood cells in a rat model of stroke dose-dependently rescues behavioral deficits and reduces infarct volume. Stroke 2004; 35: 2390-5.
    • (2004) Stroke , vol.35 , pp. 2390-2395
    • Vendrame, M.1    Cassady, J.2    Newcomb, J.3
  • 29
    • 33646708298 scopus 로고    scopus 로고
    • Spastic paresis after perinatal brain damage in rats is reduced by human cord blood mononuclear cells
    • Meier C, Middelanis J, Wasielewski B, et al. Spastic paresis after perinatal brain damage in rats is reduced by human cord blood mononuclear cells. Pediatr Res 2006; 59: 244-9.
    • (2006) Pediatr Res , vol.59 , pp. 244-249
    • Meier, C.1    Middelanis, J.2    Wasielewski, B.3
  • 30
    • 84871421339 scopus 로고    scopus 로고
    • Use of human umbilical cord blood mononuclear cells to prevent perinatal brain injury: a preclinical study
    • Dalous J, Pansiot J, Pham H, et al. Use of human umbilical cord blood mononuclear cells to prevent perinatal brain injury: a preclinical study. Stem Cells Dev 2013; 22: 169-79.
    • (2013) Stem Cells Dev , vol.22 , pp. 169-179
    • Dalous, J.1    Pansiot, J.2    Pham, H.3
  • 31
    • 77949617579 scopus 로고    scopus 로고
    • Human cord blood transplantation in a neonatal rat model of hypoxic-ischemic brain damage: functional outcome related to neuroprotection in the striatum
    • Pimentel-Coelho PM, Magalhaes ES, Lopes LM, de Azevedo LC, Santiago MF, Mendez-Otero R. Human cord blood transplantation in a neonatal rat model of hypoxic-ischemic brain damage: functional outcome related to neuroprotection in the striatum. Stem Cells Dev 2009; 19: 351-8.
    • (2009) Stem Cells Dev , vol.19 , pp. 351-358
    • Pimentel-Coelho, P.M.1    Magalhaes, E.S.2    Lopes, L.M.3    de Azevedo, L.C.4    Santiago, M.F.5    Mendez-Otero, R.6
  • 32
    • 84880171763 scopus 로고    scopus 로고
    • [accessed 20 October 2012].
    • http://www.clinicaltrials.gov/ct2/show/NCT01193660?term=NCT01193660&rank=1. 2012 [accessed 20 October 2012].
    • (2012)
  • 33
    • 84874925763 scopus 로고    scopus 로고
    • Umbilical cord blood therapy potentiated with erythropoietin for children with cerebral palsy: a double-blind, randomized, placebo-controlled trial
    • Min K, Song J, Kang JY, et al. Umbilical cord blood therapy potentiated with erythropoietin for children with cerebral palsy: a double-blind, randomized, placebo-controlled trial. Stem Cells 2013; 31: 581-91.
    • (2013) Stem Cells , vol.31 , pp. 581-591
    • Min, K.1    Song, J.2    Kang, J.Y.3
  • 34
  • 35
    • 61449171881 scopus 로고    scopus 로고
    • Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient
    • Amariglio N, Hirshberg A, Scheithauer BW, et al. Donor-derived brain tumor following neural stem cell transplantation in an ataxia telangiectasia patient. PLoS Med 2009; 6: e1000029.
    • (2009) PLoS Med , vol.6
    • Amariglio, N.1    Hirshberg, A.2    Scheithauer, B.W.3
  • 36
    • 40849085320 scopus 로고    scopus 로고
    • Invasive fungal disease in allogeneic hematopoietic stem cell transplant recipients: an autopsy-driven survey
    • Sinko J, Csomor J, Nikolova R, et al. Invasive fungal disease in allogeneic hematopoietic stem cell transplant recipients: an autopsy-driven survey. Transpl Infect Dis 2008; 10: 106-9.
    • (2008) Transpl Infect Dis , vol.10 , pp. 106-109
    • Sinko, J.1    Csomor, J.2    Nikolova, R.3
  • 37
    • 84880172275 scopus 로고    scopus 로고
    • Baby death scandal at stem cell clinic which treats hundreds of British patients a year
    • 23rd October 2010.
    • Mendick R, Palmer A. Baby death scandal at stem cell clinic which treats hundreds of British patients a year. Daily Telegraph. 23rd October 2010.
    • Daily Telegraph
    • Mendick, R.1    Palmer, A.2
  • 38
    • 84869034868 scopus 로고    scopus 로고
    • Growth factors released from gelatin hydrogel microspheres increase new neurons in the adult mouse brain
    • doi: 10.1155/2012/915160 [Epub October 10 2012].
    • Nakaguchi K, Jinnou H, Kaneko N, et al. Growth factors released from gelatin hydrogel microspheres increase new neurons in the adult mouse brain. Stem Cells Int. 2012; 2012: 915160 doi: 10.1155/2012/915160 [Epub October 10 2012].
    • (2012) Stem Cells Int , vol.2012 , pp. 915160
    • Nakaguchi, K.1    Jinnou, H.2    Kaneko, N.3
  • 39
    • 70349780053 scopus 로고    scopus 로고
    • Constraint-induced movement therapy enhanced neurogenesis and behavioral recovery after stroke in adult rats
    • Zhao C, Wang J, Zhao S, Nie Y. Constraint-induced movement therapy enhanced neurogenesis and behavioral recovery after stroke in adult rats. Tohoku J Exp Med 2009; 218: 301-8.
    • (2009) Tohoku J Exp Med , vol.218 , pp. 301-308
    • Zhao, C.1    Wang, J.2    Zhao, S.3    Nie, Y.4
  • 40
    • 3042773051 scopus 로고    scopus 로고
    • Human neural stem cells improve sensorimotor deficits in the adult rat brain with experimental focal ischemia
    • Chu K, Kim M, Park KI, et al. Human neural stem cells improve sensorimotor deficits in the adult rat brain with experimental focal ischemia. Brain Res 2004; 1016: 145-53.
    • (2004) Brain Res , vol.1016 , pp. 145-153
    • Chu, K.1    Kim, M.2    Park, K.I.3
  • 41
    • 25444455637 scopus 로고    scopus 로고
    • Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice
    • Cummings BJ, Uchida N, Tamaki SJ, et al. Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice. Proc Natl Acad Sci USA 2005; 102: 14069-74.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 14069-14074
    • Cummings, B.J.1    Uchida, N.2    Tamaki, S.J.3
  • 42
    • 84880164055 scopus 로고    scopus 로고
    • Study of HuCNS-SC cells in patients with infantile or late infantile neuronal ceroid lipofuscinosis (NCL)[database on the Internet]. clinical trials. 2010 [accessed Oct 2012]. Available from:
    • Study of HuCNS-SC cells in patients with infantile or late infantile neuronal ceroid lipofuscinosis (NCL)[database on the Internet]. clinical trials. 2010 [accessed Oct 2012]. Available from: http://www.clinicaltrials.gov/ct2/show/record/NCT00337636?term=StemCells+inc.+Batten%E2%80%99s+disease&rank=2.
  • 43
    • 84867472678 scopus 로고    scopus 로고
    • Neural stem cell engraftment and myelination in the human brain
    • Gupta N, Henry RG, Strober J, et al. Neural stem cell engraftment and myelination in the human brain. Sci Transl Med 2012; 4: 155ra37.
    • (2012) Sci Transl Med , vol.4
    • Gupta, N.1    Henry, R.G.2    Strober, J.3
  • 45
    • 70349751479 scopus 로고    scopus 로고
    • Therapeutic microinjection of autologous adult human neural stem cells and differentiated neurons for parkinson's disease: five-year post-operative outcome
    • Lévesque MF, Neuman T, Rezak M. Therapeutic microinjection of autologous adult human neural stem cells and differentiated neurons for parkinson's disease: five-year post-operative outcome. Open Stem Cell J 2009; 1: 20-9.
    • (2009) Open Stem Cell J , vol.1 , pp. 20-29
    • Lévesque, M.F.1    Neuman, T.2    Rezak, M.3
  • 46
    • 79953015414 scopus 로고    scopus 로고
    • Grafted neural progenitors integrate and restore synaptic connectivity across the injured spinal cord
    • Bonner JF, Connors TM, Silverman WF, Kowalski DP, Lemay MA, Fischer I. Grafted neural progenitors integrate and restore synaptic connectivity across the injured spinal cord. J Neurosci 2011; 31: 4675-86.
    • (2011) J Neurosci , vol.31 , pp. 4675-4686
    • Bonner, J.F.1    Connors, T.M.2    Silverman, W.F.3    Kowalski, D.P.4    Lemay, M.A.5    Fischer, I.6
  • 47
    • 75349097509 scopus 로고    scopus 로고
    • Transplantation of placenta-derived mesenchymal stromal cells upon experimental stroke in rats
    • Kranz A, Wagner DC, Kamprad M, et al. Transplantation of placenta-derived mesenchymal stromal cells upon experimental stroke in rats. Brain Res 2010; 1315: 128-36.
    • (2010) Brain Res , vol.1315 , pp. 128-136
    • Kranz, A.1    Wagner, D.C.2    Kamprad, M.3
  • 48
    • 84866994186 scopus 로고    scopus 로고
    • Design and fabrication of a biodegradable, covalently crosslinked shape-memory alginate scaffold for cell and growth factor delivery
    • Wang L, Shansky J, Borselli C, Mooney D, Vandenburgh H. Design and fabrication of a biodegradable, covalently crosslinked shape-memory alginate scaffold for cell and growth factor delivery. Tissue Eng Part A 2012; 18: 2000-7.
    • (2012) Tissue Eng Part A , vol.18 , pp. 2000-2007
    • Wang, L.1    Shansky, J.2    Borselli, C.3    Mooney, D.4    Vandenburgh, H.5
  • 49
    • 44349086935 scopus 로고    scopus 로고
    • Neonatal chimerization with human glial progenitor cells can both remyelinate and rescue the otherwise lethally hypomyelinated shiverer mouse
    • Windrem MS, Schanz SJ, Guo M, et al. Neonatal chimerization with human glial progenitor cells can both remyelinate and rescue the otherwise lethally hypomyelinated shiverer mouse. Cell Stem Cell 2008; 2: 553-65.
    • (2008) Cell Stem Cell , vol.2 , pp. 553-565
    • Windrem, M.S.1    Schanz, S.J.2    Guo, M.3
  • 50
    • 79951844898 scopus 로고    scopus 로고
    • Therapeutic efficacy of intranasally delivered mesenchymal stem cells in a rat model of Parkinson disease
    • Danielyan L, Schafer R, von Ameln-Mayerhofer A, et al. Therapeutic efficacy of intranasally delivered mesenchymal stem cells in a rat model of Parkinson disease. Rejuvenation Res 2011; 14: 3-16.
    • (2011) Rejuvenation Res , vol.14 , pp. 3-16
    • Danielyan, L.1    Schafer, R.2    von Ameln-Mayerhofer, A.3
  • 51
    • 73249114060 scopus 로고    scopus 로고
    • Safety and function of a new clinical intracerebral microinjection instrument for stem cells and therapeutics examined in the Gottingen minipig
    • Bjarkam CR, Glud AN, Margolin L, et al. Safety and function of a new clinical intracerebral microinjection instrument for stem cells and therapeutics examined in the Gottingen minipig. Stereotact Funct Neurosurg 2010; 88: 56-63.
    • (2010) Stereotact Funct Neurosurg , vol.88 , pp. 56-63
    • Bjarkam, C.R.1    Glud, A.N.2    Margolin, L.3
  • 52
    • 33748618692 scopus 로고    scopus 로고
    • Long-term fate of neural precursor cells following transplantation into developing and adult CNS
    • Lepore AC, Neuhuber B, Connors TM, et al. Long-term fate of neural precursor cells following transplantation into developing and adult CNS. Neuroscience 2006; 142: 287-304.
    • (2006) Neuroscience , vol.142 , pp. 287-304
    • Lepore, A.C.1    Neuhuber, B.2    Connors, T.M.3
  • 53
    • 84880143456 scopus 로고    scopus 로고
    • Neural repair and regeneration. [cited 2012 Dec 6th 2012]; Available from:
    • Fehlings M. Neural repair and regeneration. 2012 [cited 2012 Dec 6th 2012]; Available from: http://www.drfehlings.ca/stem-cell-information/.
    • (2012)
    • Fehlings, M.1


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