Strategies for widening the use of cord blood in hematopoietic stem cell transplantation

Haematologica

Volumn 91, Issue 5, 2006, Pages 584-587

  De Lima, Marcos ^a   Shpall, Elizabeth ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD133 ANTIGEN; CD34 ANTIGEN; CHELATING AGENT; COPPER; FLT3 LIGAND; FLUDARABINE; GRANULOCYTE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN G1; INTERLEUKIN 3; INTERLEUKIN 6; LEUKOCYTE ANTIGEN; STEM CELL FACTOR; TEPA; THROMBOPOIETIN; THYMOCYTE ANTIBODY;

ACUTE LYMPHOCYTIC LEUKEMIA; BLOOD DONOR; BONE MARROW TRANSPLANTATION; CANCER MORTALITY; CANCER RISK; CANCER SURVIVAL; CHRONIC GRAFT VERSUS HOST DISEASE; CLINICAL TRIAL; COST BENEFIT ANALYSIS; EDITORIAL; GRAFT VERSUS HOST REACTION; HEMATOLOGIC MALIGNANCY; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HLA MATCHING; HUMAN; INFECTION COMPLICATION; LEUKEMIA; MESENCHYMAL STEM CELL; MONONUCLEAR CELL; MYELOID LEUKEMIA; NEUTROPENIA; NONHUMAN; PANCYTOPENIA; THROMBOCYTOPENIA; UMBILICAL CORD BLOOD; WHOLE BODY RADIATION;

ADOLESCENT; ADULT; BLOOD CELL COUNT; BONE MARROW TRANSPLANTATION; CELLS, CULTURED; CHILD; CHILD, PRESCHOOL; COCULTURE TECHNIQUES; CORD BLOOD STEM CELL TRANSPLANTATION; EUROPE; GRAFT VS HOST DISEASE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HISTOCOMPATIBILITY; HUMANS; INFANT; INFANT, NEWBORN; LEUKOCYTE COUNT; LIVING DONORS; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STEM CELLS; MULTICENTER STUDIES; NEUTROPHILS; PATIENT SELECTION; REGISTRIES; RETROSPECTIVE STUDIES; TISSUE AND ORGAN PROCUREMENT; TRANSPLANTATION CHIMERA; TRANSPLANTATION, HOMOLOGOUS; TREATMENT OUTCOME; UNITED STATES;

EID: 33744459737     PISSN: 03906078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Editorial

References (16)

1. Gluckman E, Rocha V. Cord blood transplant: strategy of alternative donor search. Springer Semin Immunopathol 2004;26:143-54.
2. Rocha V, Labopin M, Sanz G, Arcese W, Schwerdtfeger R, Bosi A, et al. Transplants of umbilical-cord blood or bone marrow from unrelated donors in adults with acute leukemia. Acute Leukemia Working Party of European Blood and Marrow Transplant Group; Eurocord-Netcord Registry. N Engl J Med 2004;351:2276-85.
3. Laughlin MJ, Eapen M, Rubinstein P, Wagner JE, Zhang MJ, Champlin RE, et al. Outcomes after transplantation of cord blood or bone marrow from unrelated donors in adults with leukemia. N Engl J Med 2004;351:2265-75.
4. Cornetta K, Laughlin M, Carter S, Wall D, Weinthal J, Delaney C, et al. Umbilical cord blood transplantation in adults: results of the prospective Cord Blood Transplantation (COBLT). Biol Blood Marrow Transplant 2005;11:149-60.
5. Magro E, Regido C, Cabrera R, Sanjuán I, Forés R, García-Marco JA, et al. Early hematopoietic recovery after single unit unrelated cord blood transplantation in adults supported by co-infusion of mobilized stem cells from a third party donor. Haematologica 2006;91:640-8.
6. Fernandez MN, Regidor C, Cabrera R, Garcia-Marco JA, Fores R, Sanjuan I, et al. Unrelated umbilical cord blood transplants in adults: early recovery of neutrophils by supportive cotransplantation of a low number of highly purified peripheral blood CD34+ cells from an HLA-haploidentical donor. Exp Hematol 2003;102:1915-9.
7. Mathe G, Amiel JL, Schwarzenberg L, Cattan A, Schneider M. Haematopoietic chimera in man after allogeneic (homologous) bone-marrow transplantation. Control of the secondary syndrome. Specific tolerance due to the chimerism. Br Med J 1963;2:1633-8.
8. Barker JN, Weisdorf D, Wagner J. Creation of a double chimera after the transplantation of umbilical-cord blood from two partially matched unrelated donors. N Engl J Med 2001;344:1871.
9. Barker JN, Weisdorf D, Defor T, Blazar BR, McGlave PB, Miller JS, et al. Transplantation of 2 partially HLA-matched umbilical cord blood units to enhance engraftment in adults with hematologic malignancy. Blood 2005;105:1347.
10. Shpall E, Quinones R, Giller R, Zeng C, Baron AE, Jones RB, et al. Transplantation of ex vivo expanded cord blood. Biol Blood Marrow Transplant 2002;8:376.
11. McNiece I, Kubegov D, Kerzic P, Shpall EJ, Gross S. Increased expansion and differentiation of cord blood products using a two-step expansion culture. Exp Hematol 2000;28:1181-6.
12. Peled T, Landaw E, Prus A, Treves AJ, Fibach E. Cellular copper content modulates differentiation and self-renewal in cultures of cord blood-derived CD34* cells. Br J Haematol 2002;116:655-61.
13. Delaney C, Varnum-Finney B, Aoyama K, Brashem-Stein C, Bernstein I. Dose-dependent effect of the Notch ligand Delta-1 on ex vivo differentiation and in vivo marrow repopulating ability of cord blood cells. Blood 2005;106:2693-9.
14. Noort WA, Kruisselbrink AB, in't Anker PS, Kruger M, van Bezooijen RL, de Paus RA, et al. Mesenchymal stem cells promote engraftment of human umbilical cord blood-derived CD34(+) cells in NOD/SCID mice. Exp Hematol 2002;30:870-8.
15. Le Blanc K, Rasmusson I, Sundberg B, Gotherstrom C, Hassan M, Uzunel M, et al. Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells. Lancet 2004;363:1439-41.
16. Rocha V, Aversa F, Labopin M. Outcomes of unrelated cord blood and haploidentical stem cell transplantation in adults with acute leukemia. Blood 2005;106:301a[abstract].