Active component of Antrodia cinnamomea mycelia targeting head and neck cancer initiating cells through exaggerated autophagic cell death

Evidence-based Complementary and Alternative Medicine

Volumn 2013, Issue , 2013, Pages

  Chang, Ching Wen ^a   Chen, Chien Chih ^b   Wu, Meng Ju ^a   Chen, Yu Syuan ^a   Chen, Chin Chu ^c   Sheu, Sen Je ^c   Lin, Ting Wei ^c   Chou, Shiu Huey ^d   Lin, Shu Chun ^a   Liu, Chung Ji ^e   Lee, Te Chang ^f   Huang, Chih Yang ^a,g,h   Lo, Jeng Fan ^a,g,i  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b HUNGKUANG UNIVERSITY   (Taiwan)

^c Grape King Biotechnology Inc   (Taiwan)

^d FU JEN CATHOLIC UNIVERSITY   (Taiwan)

^e MACKAY MEMORIAL HOSPITAL   (Taiwan)

^f INSTITUTE OF BIOMEDICAL SCIENCES   (Taiwan)

^g CHINA MEDICAL UNIVERSITY   (Taiwan)

^h ASIA UNIVERSITY   (Taiwan)

ⁱ TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DEHYDROGENASE; ANTINEOPLASTIC AGENT; NATURAL PRODUCT; UNCLASSIFIED DRUG; YMGKI 1;

ANTRODIA CINNAMOMEA; ARTICLE; AUTOPHAGY; CELL VIABILITY; DOWN REGULATION; ENZYME INHIBITION; HEAD AND NECK CANCER; IN VIVO STUDY; MYCELIUM; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 84880141238     PISSN: 1741427X     EISSN: 17414288     Source Type: Journal    
DOI: 10.1155/2013/946451     Document Type: Article

References (49)

1. Haddad R. I., Shin D. M., Recent advances in head and neck cancer. The New England Journal of Medicine 2008 359 1143 1154 10.1056/NEJMra0707975
2. Siegel R., Naishadham D., Jemal A., Cancer statistics, 2013. A Cancer Journal for Clinicians 2013 63 1 11 30
3. Clevers H., The cancer stem cell: premises, promises and challenges. Nature Medicine 2011 17 3 313 319
4. Li Y., Laterra J., Cancer stem cells: distinct entities or dynamically regulated phenotypes? Cancer Research 2012 72 3 576 580 2-s2.0-84856541162 10.1158/0008-5472.CAN-11-3070
5. Chiou S. H., Yu C. C., Huang C. Y., Lin S. C., Liu C. J., Tsai T. H., Chou S. H., Chien C. S., Ku H. H., Lo J. F., Positive correlations of Oct-4 and Nanog in oral cancer stem-like cells and high-grade oral squamous cell carcinoma. Clinical Cancer Research 2008 14 4085 4095 10.1158/1078-0432.CCR-07- 4404
6. Morrison R., Schleicher S. M., Sun Y., Niermann K. J., Kim S., Spratt D. E., Chung C. H., Lu B., Targeting the mechanisms of resistance to chemotherapy and radiotherapy with the cancer stem cell hypothesis. Journal of Oncology 2011 2011:941876 10.1155/2011/941876
7. Tseng T. H., Chuang S. K., Hu C., Chang C. F., Huang Y. C., Lin C. W., Lee Y. J., The synthesis of morusin as a potent antitumor agent. Tetrahedron 2010 66 1335 1340
8. Chen Y. S., Wu M. J., Huang C. Y., Lin S. C., Chuang T. H., Yu C. C., Lo J. F., CD133/Src axis mediates tumor initiating property and epithelial-mesenchymal transition of head and neck cancer. PloS ONE 2011 6 11 e28053 10.1371/journal.pone.0028053
9. Wu M. J., Jan C. I., Tsay Y. G., Yu Y. H., Huang C. Y., Lin S. C., Liu C. J., Chen Y. S., Lo J. F., Yu C. C., Elimination of head and neck cancer initiating cells through targeting glucose regulated protein78 signaling. Molecular Cancer 2010 9 283 10.1186/1476-4598-9-283
10. Croker A. K., Goodale D., Chu J., Postenka C., Hedley B. D., Hess D. A., Allan A. L., High aldehyde dehydrogenase and expression of cancer stem cell markers selects for breast cancer cells with enhanced malignant and metastatic ability. Journal of Cellular and Molecular Medicine 2009 13 8 2236 2252 2-s2.0-72949118673 10.1111/j.1582-4934.2008.00455.x
11. Wang L., Park P., Zhang H., La Marca F., Lin C., Prospective identification of tumorigenic osteosarcoma cancer stem cells in OS99-1 cells based on high aldehyde dehydrogenase activity. International Journal of Cancer 2011 128 2 294 303 2-s2.0-78649580167 10.1002/ijc.25331
12. Chen Z. G., The cancer stem cell concept in progression of head and neck cancer. Journal of Oncology 2009 2009 894064 10.1155/2009/894064
13. Lo J. F., Yu C. C., Chiou S. H., Huang C. Y., Jan C. I., Lin S. C., Liu C. J., Hu W. Y., Yu Y. H., The epithelial-mesenchymal transition mediator S100A4 maintains cancer-initiating cells in head and neck cancers. Cancer Research 2011 71 5 1912 1923 10.1158/0008-5472.CAN-10-2350
14. Janku F., McConkey D. J., Hong D. S., Kurzrock R., Autophagy as a target for anticancer therapy. Nature Reviews Clinical Oncology 2011 8 528 539
15. Apel A., Zentgraf H., Büchler M. W., Herr I., Autophagy-a double-edged sword in oncology. International Journal of Cancer 2009 125 5 991 995 2-s2.0-67650021571 10.1002/ijc.24500
16. Chaterjee M., van Golen K. L., Breast cancer stem cells survive periods of farnesyl-transferase inhibitor-induced dormancy by undergoing autophagy. Bone Marrow Research 2011 2011 362938 10.1155/2011/362938
17. Zhuang W., Li B., Long L., Chen L., Huang Q., Liang Z., Induction of autophagy promotes differentiation of glioma-initiating cells and their radiosensitivity. International Journal of Cancer 2011 129 11 2720 2731 2-s2.0-80053302394 10.1002/ijc.25975
18. Kwatra D., Subramaniam D., Ramamoorthy P., Standing D., Moran E., Velayutham R., Mitra A., Umar S., Anant S., Methanolic extracts of bitter melon inhibit colon cancer stem cells by affecting energy homeostasis and autophagy. Evidence-Based Complementary and Alternative Medicine 2013 2013 14 702869 10.1155/2013/702869
19. Shen Y., Yang S., Lin C., Chen C., Kuo Y., Chen C., Zhankuic acid F: a new metabolite from a formosan fungus Antrodia cinnamomea. Planta Medica 1997 63 1 86 88 2-s2.0-0031051721 10.1055/s-2006-957614
20. Wu M. D., Cheng M. J., Wang W. Y., Huang H. C., Yuan G. F., Chen J. J., Chen I. S., Wang B. C., Antioxidant activities of extracts and metabolites isolated from the fungus Antrodia cinnamomea. Natural Product Research 2011 25 16 1488 1496 10.1080/14786410903132563
21. Lee C. C., Yang H. L., Way T. D., Kumar K. J., Juan Y. C., Cho H. J., Lin K. Y., Hsu L. S., Chen S. C., Hseu Y. C., Inhibition of cell growth and induction of apoptosis by Antrodia camphorata in HER-2/neu-overexpressing breast cancer cells through the induction of ROS, depletion of HER-2/neu, and disruption of the PI3K/Akt signaling pathway. Evidence-Based Complementary and Alternative Medicine 2012 2012 702857 10.1155/2012/702857
22. Wen C., Chang C., Huang S., Kuo C., Hsu S., Deng J., Huang G., Anti-inflammatory effects of methanol extract of Antrodia cinnamomea mycelia both in vitro and in vivo. Journal of Ethnopharmacology 2011 137 1 575 584 2-s2.0-80052024426 10.1016/j.jep.2011.06.009
23. Ho Y., Lin M., Duan K., Chen Y., The hepatoprotective activity against ethanol-induced cytotoxicity by aqueous extract of Antrodia cinnamomea. Journal of the Chinese Institute of Chemical Engineers 2008 39 5 441 447 2-s2.0-56949107767 10.1016/j.jcice.2008.03.008
24. Hseu Y. C., Tsou H. T., Kumar K. J., Lin K. Y., Chang H. W., Yang H. L., The antitumor activity of Antrodia camphorata in melanoma cells: modulation of wnt/ β -catenin signaling pathways. Evidence-Based Complementary and Alternative Medicine 2012 2012 197309 10.1155/2012/197309
25. Tzeng Y., Geethangili M., Review of pharmacological effects of Antrodia camphorata and its bioactive compounds. Evidence-based Complementary and Alternative Medicine 2011 2011 2-s2.0-79952231175 10.1093/ecam/nep108 212641
26. Nakamura N., Hirakawa A., Gao J., Kakuda H., Shiro M., Komatsu Y., Sheu C., Hattori M., Five new maleic and succinic acid derivatives from the mycelium of Antrodia camphorata and their cytotoxic effects on LLC tumor cell line. Journal of Natural Products 2004 67 1 46 48 2-s2.0-0942269010 10.1021/np030293k
27. Okumura K., Konishi A., Tanaka M., Kanazawa M., Kogawa K., Niitsu Y., Establishment of high- and low-invasion clones derived for a human tongue squamous-cell carcinoma cell line SAS. Journal of Cancer Research and Clinical Oncology 1996 122 4 243 248 2-s2.0-0029866056
28. Hsin I. L., Ou C., Wu T., Jan M., Wu M., Chiu L., Lue K., Ko J., GMI, an immunomodulatory protein from Ganoderma microsporum, induces autophagy in non-small cell lung cancer cells. Autophagy 2011 7 8 873 882 2-s2.0-79961109801 10.4161/auto.7.8.15698
29. Clay M. R., Tabor M., Owen J. H., Carey T. E., Bradford C. R., Wolf G. T., Wicha M. S., Prince M. E., Single-marker identification of head and neck squamous cell carcinoma cancer stem cells with aldehyde dehydrogenase. Head and Neck 2010 32 9 1195 1201 2-s2.0-77954901231 10.1002/hed.21315
30. Keysar S. B., Jimeno A., More than markers: biological significance of cancer stem cell-defining molecules. Molecular Cancer Therapeutics 2010 9 9 2450 2457 2-s2.0-77956574908 10.1158/1535-7163.MCT-10-0530
31. Bacsó Z., Everson R. B., Eliason J. F., The DNA of annexin V-binding apoptotic cells is highly fragmented. Cancer Research 2000 60 16 4623 4628 2-s2.0-0034662611
32. Takeuchi H., Kondo Y., Fujiwara K., Kanzawa T., Aoki H., Mills G. B., Kondo S., Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors. Cancer Research 2005 65 8 3336 3346 2-s2.0-17144427728
33. Kondo Y., Kanzawa T., Sawaya R., Kondo S., The role of autophagy in cancer development and response to therapy. Nature Reviews Cancer 2005 5 9 726 734 2-s2.0-25444440875 10.1038/nrc1692
34. Mathew R., Karantza-Wadsworth V., White E., Role of autophagy in cancer. Nature Reviews Cancer 2007 7 12 961 967 2-s2.0-36448943299 10.1038/nrc2254
35. Martelli A. M., Evangelisti C., Chiarini F., Grimaldi C., Cappellini A., Ognibene A., McCubrey J. A., The emerging role of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in normal myelopoiesis and leukemogenesis. Biochimica et Biophysica Acta 2010 1803 9 991 1002 2-s2.0-77954955537 10.1016/j.bbamcr.2010.04.005
36. Korkaya H., Paulson A., Iovino F., Wicha M. S., HER2 regulates the mammary stem/progenitor cell population driving tumorigenesis and invasion. Oncogene 2008 27 47 6120 6130 2-s2.0-54049096261 10.1038/onc.2008.207
37. Meijer A. J., Codogno P., AMP-activated protein kinase and autophagy. Autophagy 2007 3 3 238 240
38. Sato A., Sunayama J., Okada M., Watanabe E., Seino S., Shibuya K., Suzuki K., Narita Y., Shibui S., Kayama T., Kitanaka C., Glioma-initiating cell elimination by metformin activation of FOXO3 via AMPK. Stem Cells Translational Medicine 2012 1 11 811 824 10.5966/sctm.2012-0058
39. Chen D., Pamu S., Cui Q., Chan T. H., Dou Q. P., Novel epigallocatechin gallate (EGCG) analogs activate AMP-activated protein kinase pathway and target cancer stem cells. Bioorganic and Medicinal Chemistry 2012 20 9 3031 3037 2-s2.0-84859900206 10.1016/j.bmc.2012.03.002
40. Li H. J., Reinhardt F., Herschman H. R., Weinberg R. A., Cancer-stimulated mesenchymal stem cells create a carcinoma stem cell niche via prostaglandin E2 signaling. Cancer Discovery 2012 2 9 840 855 10.1158/2159-8290.CD-12-0101
41. Shin V. Y., Jin H. C., Ng E. K. O., Sung J. J. Y., Chu K. M., Cho C. H., Activation of 5-lipoxygenase is required for nicotine mediated epithelial-mesenchymal transition and tumor cell growth. Cancer Letters 2010 292 2 237 245
42. -/low breast cancer stem-like phenotype. Cell Cycle 2011 10 22 3871 3885 2-s2.0-80655140436 10.4161/cc.10.22.17976
43. Kondo Y., Kondo S., Autophagy and cancer therapy. Autophagy 2006 2 2 85 90
44. Wullschleger S., Loewith R., Hall M. N., TOR signaling in growth and metabolism. Cell 2006 124 3 471 484
45. Charafe-Jauffret E., Ginestier C., Iovino F., Wicinski J., Cervera N., Finetti P., Hur M., Diebel M. E., Monville F., Dutcher J., Brown M., Viens P., Xerri L., Bertucci F., Stassi G., Dontu G., Birnbaum D., Wicha M. S., Breast cancer cell lines contain functional cancer stem sells with metastatic capacity and a distinct molecular signature. Cancer Research 2009 69 4 1302 1313 2-s2.0-60549111070 10.1158/0008-5472.CAN-08-2741
46. Todaro M., Iovino F., Eterno V., Cammareri P., Gambara G., Espina V., Gulotta G., Dieli F., Giordano S., De Maria R., Stassi G., Tumorigenic and metastatic activity of human thyroid cancer stem cells. Cancer Research 2010 70 21 8874 8885 2-s2.0-78449281896 10.1158/0008-5472.CAN-10-1994
47. Howells L. M., Sale S., Sriramareddy S. N., Irving G. R. B., Jones D. J. L., Ottley C. J., Pearson D. G., Mann C. D., Manson M. M., Berry D. P., Gescher A., Steward W. P., Brown K., Curcumin ameliorates oxaliplatin-induced chemoresistance in HCT116 colorectal cancer cells in vitro and in vivo. International Journal of Cancer 2011 129 2 476 486 2-s2.0-79961109379 10.1002/ijc.25670
48. Kim L. C., Song L., Haura E. B., Src kinases as therapeutic targets for cancer. Nature Reviews Clinical Oncology 2009 6 587 595
49. Zhang S., Huang W., Li P., Guo H., Poh S., Brady S. W., Xiong Y., Tseng L., Li S., Ding Z., Sahin A. A., Esteva F. J., Hortobagyi G. N., Yu D., Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways. Nature Medicine 2011 17 4 461 469 2-s2.0-79953745096 10.1038/nm.2309