메뉴 건너뛰기




Volumn 13, Issue 4, 2013, Pages 533-549

Painful and painless diabetic neuropathy: One disease or two?

Author keywords

Autonomic neuropathy; Biomarkers; Central plasticity; Diabetic neuropathy; Epidemiology; Genetics; Inflammation; Neuropathic pain; Pain mechanisms; Painful; Painful neuropathy; Painless; Painless neuropathy; Predictors; Risk factors; Small fiber neuropathy

Indexed keywords

C PEPTIDE;

EID: 84880134135     PISSN: 15344827     EISSN: 15390829     Source Type: Journal    
DOI: 10.1007/s11892-013-0387-7     Document Type: Article
Times cited : (68)

References (146)
  • 1
    • 78651101592 scopus 로고    scopus 로고
    • Diabetic neuropathies: Update on definitions, diagnostic criteria, estimation of severity, and treatments
    • 20876709 This paper is the summary report of the Toronto consensus meeting on diabetic neuropathy. It provides novel insights into the definition and diagnosis of different forms of diabetic neuropathy
    • • Tesfaye S, Boulton AJ, Dyck PJ, Freeman R, Horowitz M, Kempler P, et al. Diabetic neuropathies: update on definitions, diagnostic criteria, estimation of severity, and treatments. Diabetes Care. 2010;33:2285-93. This paper is the summary report of the Toronto consensus meeting on diabetic neuropathy. It provides novel insights into the definition and diagnosis of different forms of diabetic neuropathy.
    • (2010) Diabetes Care , vol.33 , pp. 2285-2293
    • Tesfaye, S.1    Boulton, A.J.2    Dyck, P.J.3    Freeman, R.4    Horowitz, M.5    Kempler, P.6
  • 2
    • 42949154269 scopus 로고    scopus 로고
    • Neuropathic pain: Redefinition and a grading system for clinical and research purposes
    • 18003941 1:CAS:528:DC%2BD1cXltVWnt7Y%3D
    • Treede RD, Jensen TS, Campbell JN, Cruccu G, Dostrovsky JO, Griffin JW, et al. Neuropathic pain: redefinition and a grading system for clinical and research purposes. Neurology. 2008;70:1630-5.
    • (2008) Neurology , vol.70 , pp. 1630-1635
    • Treede, R.D.1    Jensen, T.S.2    Campbell, J.N.3    Cruccu, G.4    Dostrovsky, J.O.5    Griffin, J.W.6
  • 3
    • 4544367196 scopus 로고    scopus 로고
    • Chronic painful peripheral neuropathy in an urban community: A controlled comparison of people with and without diabetes
    • 15317601 1:STN:280:DC%2BD2cvhtlWntw%3D%3D
    • Daousi C, MacFarlane IA, Woodward A, Nurmikko TJ, Bundred PE, Benbow SJ. Chronic painful peripheral neuropathy in an urban community: a controlled comparison of people with and without diabetes. Diabet Med. 2004;21:976-82.
    • (2004) Diabet Med , vol.21 , pp. 976-982
    • Daousi, C.1    Macfarlane, I.A.2    Woodward, A.3    Nurmikko, T.J.4    Bundred, P.E.5    Benbow, S.J.6
  • 4
    • 33746441608 scopus 로고    scopus 로고
    • The prevalence, severity, and impact of painful diabetic peripheral neuropathy in type 2 diabetes
    • 16801572
    • Davies M, Brophy S, Williams R, Taylor A. The prevalence, severity, and impact of painful diabetic peripheral neuropathy in type 2 diabetes. Diabetes Care. 2006;29:1518-22.
    • (2006) Diabetes Care , vol.29 , pp. 1518-1522
    • Davies, M.1    Brophy, S.2    Williams, R.3    Taylor, A.4
  • 5
    • 62349139024 scopus 로고    scopus 로고
    • Neuropathic pain in diabetes, prediabetes and normal glucose tolerance: The MONICA/KORA Augsburg Surveys S2 and S3
    • Kora Study Group
    • Ziegler D, Rathmann W, Dickhaus T, Meisinger C, Mielck A, KORA Study Group. Neuropathic pain in diabetes, prediabetes and normal glucose tolerance: the MONICA/KORA Augsburg Surveys S2 and S3. Pain Med. 2009;10:393-400.
    • (2009) Pain Med. , vol.10 , pp. 393-400
    • Ziegler, D.1    Rathmann, W.2    Dickhaus, T.3    Meisinger, C.4    Mielck, A.5
  • 6
    • 67349187994 scopus 로고    scopus 로고
    • Prevalence and impact on quality of life of peripheral neuropathy with or without neuropathic pain in type 1 and type 2 diabetic patients attending hospital outpatients clinics
    • 19297223
    • Van Acker K, Bouhassira D, De Bacquer D, Weiss S, Matthys K, Raemen H, et al. Prevalence and impact on quality of life of peripheral neuropathy with or without neuropathic pain in type 1 and type 2 diabetic patients attending hospital outpatients clinics. Diabetes Metab. 2009;35:206-13.
    • (2009) Diabetes Metab , vol.35 , pp. 206-213
    • Van Acker, K.1    Bouhassira, D.2    De Bacquer, D.3    Weiss, S.4    Matthys, K.5    Raemen, H.6
  • 7
    • 84860818001 scopus 로고    scopus 로고
    • Prevalence and characteristics of painful diabetic neuropathy in a large community-based diabetic population in the U.K
    • 21852677
    • Abbott CA, Malik RA, van Ross ER, Kulkarni J, Boulton AJ. Prevalence and characteristics of painful diabetic neuropathy in a large community-based diabetic population in the U.K. Diabetes Care. 2011;34:2220-4.
    • (2011) Diabetes Care , vol.34 , pp. 2220-2224
    • Abbott, C.A.1    Malik, R.A.2    Van Ross, E.R.3    Kulkarni, J.4    Boulton, A.J.5
  • 8
    • 78049482348 scopus 로고    scopus 로고
    • Prevalence of distal diabetic polyneuropathy using quantitative sensory methods in a population with diabetes of more than 10 years' disease duration
    • Sociedad Española de Endocrinología y Nutrición Nutrición. Miralles-García Jm
    • Miralles-García JM, de Pablos-Velasco P, Cabrerizo L, Pérez M, López-Gómez V, Sociedad Española de Endocrinologí a y Nutrición. Prevalence of distal diabetic polyneuropathy using quantitative sensory methods in a population with diabetes of more than 10 years' disease duration. Endocrinol Nutr. 2010;57:414-20.
    • (2010) Endocrinol Nutr. , vol.57 , pp. 414-420
    • De Pablos-Velasco P, C.1
  • 9
    • 0030991905 scopus 로고    scopus 로고
    • A multicenter study on the prevalence of diabetic neuropathy in Italy. Italian Diabetic neuropathy Committee
    • 9135952 1:STN:280:DyaK2s3otFKntg%3D%3D
    • Fedele D, Comi G, Coscelli C, Cucinotta D, Feldman EL, Ghirlanda G, et al. A multicenter study on the prevalence of diabetic neuropathy in Italy. Italian Diabetic neuropathy Committee. Diabetes Care. 1997;20:836-43.
    • (1997) Diabetes Care , vol.20 , pp. 836-843
    • Fedele, D.1    Comi, G.2    Coscelli, C.3    Cucinotta, D.4    Feldman, E.L.5    Ghirlanda, G.6
  • 10
    • 2642567089 scopus 로고    scopus 로고
    • Epidemiology of diabetic neuropathy
    • F.A. Gries N.E. Cameron A. Low D. Ziegler (eds) Thieme Stuttgard
    • Shaw JE, Zimmet PZ, Gries FA, Ziegler D. Epidemiology of diabetic neuropathy. In: Gries FA, Cameron NE, Low PA, Ziegler D, editors. Textbook of diabetic neuropathy. Stuttgard: Thieme; 2003. p. 64-82.
    • (2003) Textbook of Diabetic Neuropathy , pp. 64-82
    • Shaw, J.E.1    Zimmet, P.Z.2    Gries, F.A.3    Ziegler, D.4
  • 11
    • 27344458828 scopus 로고    scopus 로고
    • Pain severity in diabetic peripheral neuropathy is associated with patient functioning, symptom levels of anxiety and depression, and sleep
    • Gore M, Brandenburg NA, Dukes E, Hoffman DL, Tai KS, Stacey B, et al. Pain severity in diabetic peripheral neuropathy is associated with patient functioning, symptom levels of anxiety and depression, and sleep. J Pain Symptom Manag. 2005;30:374-85.
    • (2005) J Pain Symptom Manag , vol.30 , pp. 374-385
    • Gore, M.1    Brandenburg, N.A.2    Dukes, E.3    Hoffman, D.L.4    Tai, K.S.5    Stacey, B.6
  • 12
    • 29744444507 scopus 로고    scopus 로고
    • Painful diabetic neuropathy: A cross-sectional survey of health state impairment and treatment patterns
    • 16389164
    • Tölle T, Xu X, Sadosky AB. Painful diabetic neuropathy: a cross-sectional survey of health state impairment and treatment patterns. J Diabetes Complications. 2006;20:26-33.
    • (2006) J Diabetes Complications , vol.20 , pp. 26-33
    • Tölle, T.1    Xu, X.2    Sadosky, A.B.3
  • 13
    • 77954855510 scopus 로고    scopus 로고
    • Does pain cause the perception of fatigue in patients with chronic pain? Findings from studies for management of diabetic peripheral neuropathic pain with duloxetine
    • 19500272
    • Fishbain DA, Hall JA, Risser RC, Gonzales JS. Does pain cause the perception of fatigue in patients with chronic pain? Findings from studies for management of diabetic peripheral neuropathic pain with duloxetine. Pain Pract. 2009;9:354-62.
    • (2009) Pain Pract , vol.9 , pp. 354-362
    • Fishbain, D.A.1    Hall, J.A.2    Risser, R.C.3    Gonzales, J.S.4
  • 14
    • 77951765536 scopus 로고    scopus 로고
    • The burden of neuropathic pain: A systematic review and meta-analysis of health utilities
    • 20227832
    • Doth AH, Hansson PT, Jensen MP, Taylor RS. The burden of neuropathic pain: a systematic review and meta-analysis of health utilities. Pain. 2010;149:338-44.
    • (2010) Pain , vol.149 , pp. 338-344
    • Doth, A.H.1    Hansson, P.T.2    Jensen, M.P.3    Taylor, R.S.4
  • 15
    • 77950343387 scopus 로고    scopus 로고
    • Assessment and treatment of psychosocial comorbidities in patients with neuropathic pain
    • 20194148
    • Turk DC, Audette J, Levy RM, Mackey SC, Stanos S. Assessment and treatment of psychosocial comorbidities in patients with neuropathic pain. Mayo Clin Proc. 2010;85:S42-50.
    • (2010) Mayo Clin Proc , vol.85 , pp. 42-50
    • Turk, D.C.1    Audette, J.2    Levy, R.M.3    Mackey, S.C.4    Stanos, S.5
  • 17
    • 75249105058 scopus 로고    scopus 로고
    • What is the evidence for chronic pain being etiologically associated with the DSM-IV category of sleep disorder due to a general medical condition? A structured evidence-based review
    • 19788712
    • Fishbain DA, Cole B, Lewis JE, Gao J. What is the evidence for chronic pain being etiologically associated with the DSM-IV category of sleep disorder due to a general medical condition? A structured evidence-based review. Pain Med. 2010;11:158-79.
    • (2010) Pain Med , vol.11 , pp. 158-179
    • Fishbain, D.A.1    Cole, B.2    Lewis, J.E.3    Gao, J.4
  • 18
    • 67649445910 scopus 로고    scopus 로고
    • Comorbidities, healthcare service utilization and costs for patients identified with painful DPN in a managed-care setting
    • 19419344
    • Ritzwoller DP, Ellis JL, Korner EJ, Hartsfield CL, Sadosky A. Comorbidities, healthcare service utilization and costs for patients identified with painful DPN in a managed-care setting. Curr Med Res Opin. 2009;25:1319-28.
    • (2009) Curr Med Res Opin , vol.25 , pp. 1319-1328
    • Ritzwoller, D.P.1    Ellis, J.L.2    Korner, E.J.3    Hartsfield, C.L.4    Sadosky, A.5
  • 19
    • 79955910729 scopus 로고    scopus 로고
    • Association between pain severity and health care resource use, health status, productivity and related costs in painful diabetic peripheral neuropathy patients
    • 21481171
    • DiBonaventura MD, Cappelleri JC, Joshi AV. Association between pain severity and health care resource use, health status, productivity and related costs in painful diabetic peripheral neuropathy patients. Pain Med. 2011;12:799-807.
    • (2011) Pain Med , vol.12 , pp. 799-807
    • Dibonaventura, M.D.1    Cappelleri, J.C.2    Joshi, A.V.3
  • 20
    • 84865596036 scopus 로고    scopus 로고
    • Management of painful diabetic neuropathy: Guideline guidance or jungle?
    • 22623150 This paper provides a critical evaluation of the guidelines on the management of neuropathic pain
    • • Spallone V. Management of painful diabetic neuropathy: guideline guidance or jungle? Curr Diab Rep. 2012;12:403-13. This paper provides a critical evaluation of the guidelines on the management of neuropathic pain.
    • (2012) Curr Diab Rep , vol.12 , pp. 403-413
    • Spallone, V.1
  • 23
    • 20044376310 scopus 로고    scopus 로고
    • Comparison of pain syndromes associated with nervous or somatic lesions and development of a new neuropathic pain diagnostic questionnaire (DN4)
    • 15733628
    • Bouhassira D, Attal N, Alchaar H, Boureau F, Brochet B, Bruxelle J, et al. Comparison of pain syndromes associated with nervous or somatic lesions and development of a new neuropathic pain diagnostic questionnaire (DN4). Pain. 2005;114:29-36.
    • (2005) Pain , vol.114 , pp. 29-36
    • Bouhassira, D.1    Attal, N.2    Alchaar, H.3    Boureau, F.4    Brochet, B.5    Bruxelle, J.6
  • 24
    • 84859824037 scopus 로고    scopus 로고
    • Validation of DN4 as a screening tool for neuropathic pain in painful diabetic polyneuropathy
    • 22023377 1:CAS:528:DC%2BC38XpsVKnt7s%3D This is the first validation study of the screening tool DN4 for painful diabetic polyneuropathy with values of sensitivity and specificity of 80% and 92%, respectively
    • • Spallone V, Morganti R, D'Amato C, Greco C, Cacciotti L, Marfia GA. Validation of DN4 as a screening tool for neuropathic pain in painful diabetic polyneuropathy. Diabet Med. 2012;29:578-85. This is the first validation study of the screening tool DN4 for painful diabetic polyneuropathy with values of sensitivity and specificity of 80% and 92%, respectively.
    • (2012) Diabet Med , vol.29 , pp. 578-585
    • Spallone, V.1    Morganti, R.2    D'Amato, C.3    Greco, C.4    Cacciotti, L.5    Marfia, G.A.6
  • 25
    • 74549168379 scopus 로고    scopus 로고
    • Prevalence of painful diabetic peripheral neuropathy among patients suffering from diabetes mellitus in Saudi Arabia
    • 19968592
    • Halawa MR, Karawagh A, Zeidan A, Mahmoud AE, Sakr M, Hegazy A. Prevalence of painful diabetic peripheral neuropathy among patients suffering from diabetes mellitus in Saudi Arabia. Curr Med Res Opin. 2010;26:337-43.
    • (2010) Curr Med Res Opin , vol.26 , pp. 337-343
    • Halawa, M.R.1    Karawagh, A.2    Zeidan, A.3    Mahmoud, A.E.4    Sakr, M.5    Hegazy, A.6
  • 26
    • 79955657951 scopus 로고    scopus 로고
    • Prevalence of painful diabetic peripheral neuropathy among patients with diabetes mellitus in the Middle East region
    • 21672340 1:STN:280:DC%2BC3MngsFaisw%3D%3D This is a large epidemiological study of painful diabetic neuropathy in the Middle East Region
    • • Jambart S, Ammache Z, Haddad F, Younes A, Hassoun A, Abdalla K, et al. Prevalence of painful diabetic peripheral neuropathy among patients with diabetes mellitus in the Middle East region. J Int Med Res. 2011;39:366-77. This is a large epidemiological study of painful diabetic neuropathy in the Middle East Region.
    • (2011) J Int Med Res , vol.39 , pp. 366-377
    • Jambart, S.1    Ammache, Z.2    Haddad, F.3    Younes, A.4    Hassoun, A.5    Abdalla, K.6
  • 27
    • 19944433694 scopus 로고    scopus 로고
    • Vascular risk factors and diabetic neuropathy.EURODIAB Prospective Complications Study Group
    • 15673800 1:CAS:528:DC%2BD2MXnvVKntw%3D%3D
    • Tesfaye S, Chaturvedi N, Eaton SE, Ward JD, Manes C, Ionescu-Tirgoviste C, et al. Vascular risk factors and diabetic neuropathy.EURODIAB Prospective Complications Study Group. N Engl J Med. 2005;352:341-50.
    • (2005) N Engl J Med , vol.352 , pp. 341-350
    • Tesfaye, S.1    Chaturvedi, N.2    Eaton, S.E.3    Ward, J.D.4    Manes, C.5    Ionescu-Tirgoviste, C.6
  • 28
    • 0029038374 scopus 로고
    • Natural history of peripheral neuropathy in patients with non-insulin-dependent diabetes mellitus
    • Partanen J, Niskanen L, Lehtinen J, Mervaala E, Siitonen O, Uusitupa M. Natural history of peripheral neuropathy in patients with non-insulin-dependent diabetes mellitus. N Engl J Med. 1995;13:89-94.
    • (1995) N Engl J Med , vol.13 , pp. 89-94
    • Partanen, J.1    Niskanen, L.2    Lehtinen, J.3    Mervaala, E.4    Siitonen, O.5    Uusitupa, M.6
  • 29
    • 0036234429 scopus 로고    scopus 로고
    • Insensate vs painful diabetic neuropathy: The effects of height, gender, ethnicity and glycemic control
    • 12007729 1:CAS:528:DC%2BD38Xjtl2itLc%3D
    • Sorensen L, Molyneaux L, Yue DK. Insensate vs painful diabetic neuropathy: the effects of height, gender, ethnicity and glycemic control. Diabetes Res Clin Pract. 2002;57:45-51.
    • (2002) Diabetes Res Clin Pract , vol.57 , pp. 45-51
    • Sorensen, L.1    Molyneaux, L.2    Yue, D.K.3
  • 30
    • 34447650793 scopus 로고    scopus 로고
    • Cardiovascular risk factors predicting the development of distal symmetrical polyneuropathy in people with type 1 diabetes: A 9-year follow-up study
    • 17151310
    • Sibal L, Law HN, Gebbie J, Home P. Cardiovascular risk factors predicting the development of distal symmetrical polyneuropathy in people with type 1 diabetes: a 9-year follow-up study. Ann N Y Acad Sci. 2006;1084:304-18.
    • (2006) Ann N y Acad Sci , vol.1084 , pp. 304-318
    • Sibal, L.1    Law, H.N.2    Gebbie, J.3    Home, P.4
  • 31
    • 44449144074 scopus 로고    scopus 로고
    • Prevalence of polyneuropathy in pre-diabetes and diabetes is associated with abdominal obesity and macroangiopathy: The MONICA/KORA Augsburg Surveys S2 and S3
    • Kora Study Group
    • Ziegler D, Rathmann W, Dickhaus T, Meisinger C, Mielck A, KORA Study Group. Prevalence of polyneuropathy in pre-diabetes and diabetes is associated with abdominal obesity and macroangiopathy: the MONICA/KORA Augsburg Surveys S2 and S3. Diabetes Care. 2008;31:464-9.
    • (2008) Diabetes Care. , vol.31 , pp. 464-469
    • Ziegler, D.1    Rathmann, W.2    Dickhaus, T.3    Meisinger, C.4    Mielck, A.5
  • 32
    • 67349203154 scopus 로고    scopus 로고
    • Prevalence and risk factors of neuropathic pain in survivors of myocardial infarction with pre-diabetes and diabetes
    • Kora Study Group
    • Ziegler D, Rathmann W, Meisinger C, Dickhaus T, Mielck A, KORA Study Group. Prevalence and risk factors of neuropathic pain in survivors of myocardial infarction with pre-diabetes and diabetes. The KORA Myocardial Infarction Registry. Eur J Pain. 2009;13:582-7.
    • (2009) The KORA Myocardial Infarction Registry. Eur J Pain , vol.13 , pp. 582-587
    • Ziegler, D.1    Rathmann, W.2    Meisinger, C.3    Dickhaus, T.4    Mielck, A.5
  • 33
    • 61849139579 scopus 로고    scopus 로고
    • Fasting plasma C-peptide and micro- and macrovascular complications in a large clinic-based cohort of type 1 diabetic patients
    • 19017769 1:CAS:528:DC%2BD1MXis1Wrs7Y%3D
    • Panero F, Novelli G, Zucco C, Fornengo P, Perotto M, Segre O, et al. Fasting plasma C-peptide and micro- and macrovascular complications in a large clinic-based cohort of type 1 diabetic patients. Diabetes Care. 2009;32:301-5.
    • (2009) Diabetes Care , vol.32 , pp. 301-305
    • Panero, F.1    Novelli, G.2    Zucco, C.3    Fornengo, P.4    Perotto, M.5    Segre, O.6
  • 35
    • 41149125988 scopus 로고    scopus 로고
    • Lipid-lowering therapy and peripheral sensory neuropathy in type 2 diabetes: The Fremantle Diabetes Study
    • 18193189 1:CAS:528:DC%2BD1cXjsFGiurs%3D
    • Davis TM, Yeap BB, Davis WA, Bruce DG. Lipid-lowering therapy and peripheral sensory neuropathy in type 2 diabetes: the Fremantle Diabetes Study. Diabetologia. 2008;51:562-6.
    • (2008) Diabetologia , vol.51 , pp. 562-566
    • Davis, T.M.1    Yeap, B.B.2    Davis, W.A.3    Bruce, D.G.4
  • 36
    • 67650269861 scopus 로고    scopus 로고
    • Elevated triglycerides correlate with progression of diabetic neuropathy
    • 19411614 1:CAS:528:DC%2BD1MXos1Cqu70%3D
    • Wiggin TD, Sullivan KA, Pop-Busui R, Amato A, Sima AA, Feldman EL. Elevated triglycerides correlate with progression of diabetic neuropathy. Diabetes. 2009;58:1634-40.
    • (2009) Diabetes , vol.58 , pp. 1634-1640
    • Wiggin, T.D.1    Sullivan, K.A.2    Pop-Busui, R.3    Amato, A.4    Sima, A.A.5    Feldman, E.L.6
  • 37
    • 79956213781 scopus 로고    scopus 로고
    • Protection from retinopathy and other complications in patients with type 1 diabetes of extreme duration: The joslin 50-year medalist study
    • 21447665
    • Sun JK, Keenan HA, Cavallerano JD, Asztalos BF, Schaefer EJ, Sell DR, et al. Protection from retinopathy and other complications in patients with type 1 diabetes of extreme duration: the joslin 50-year medalist study. Diabetes Care. 2011;34:968-74.
    • (2011) Diabetes Care , vol.34 , pp. 968-974
    • Sun, J.K.1    Keenan, H.A.2    Cavallerano, J.D.3    Asztalos, B.F.4    Schaefer, E.J.5    Sell, D.R.6
  • 38
    • 0027382357 scopus 로고
    • Symptoms of sensory neuropathy in adults with NIDDM in the U.S. population
    • 8299433 1:STN:280:DyaK2c7jtVKhsQ%3D%3D
    • Harris M, Eastman R, Cowie C. Symptoms of sensory neuropathy in adults with NIDDM in the U.S. population. Diabetes Care. 1993;16:1446-52.
    • (1993) Diabetes Care , vol.16 , pp. 1446-1452
    • Harris, M.1    Eastman, R.2    Cowie, C.3
  • 39
    • 79251596558 scopus 로고    scopus 로고
    • Clinical correlates of painful diabetic neuropathy and relationship of neuropathic pain with sensorimotor and autonomic nerve function
    • 20619708
    • Spallone V, Morganti R, D'Amato C, Cacciotti L, Fedele T, Maiello MR, et al. Clinical correlates of painful diabetic neuropathy and relationship of neuropathic pain with sensorimotor and autonomic nerve function. Eur J Pain. 2011;15:153-60.
    • (2011) Eur J Pain , vol.15 , pp. 153-160
    • Spallone, V.1    Morganti, R.2    D'Amato, C.3    Cacciotti, L.4    Fedele, T.5    Maiello, M.R.6
  • 40
    • 36049041645 scopus 로고    scopus 로고
    • Estimated prevalence of peripheral neuropathy and associated pain in adults with diabetes in France
    • 17637204 1:STN:280:DC%2BD2sritl2qtQ%3D%3D
    • Wu EQ, Borton J, Said G, Le TK, Monz B, Rosilio M, et al. Estimated prevalence of peripheral neuropathy and associated pain in adults with diabetes in France. Curr Med Res Opin. 2007;23:2035-42.
    • (2007) Curr Med Res Opin , vol.23 , pp. 2035-2042
    • Wu, E.Q.1    Borton, J.2    Said, G.3    Le, T.K.4    Monz, B.5    Rosilio, M.6
  • 41
    • 79951675299 scopus 로고    scopus 로고
    • Prevalence of peripheral neuropathy and painful peripheral neuropathy in Turkish diabetic patients
    • Turnep Study Group
    • Erbas T, Ertas M, Yucel A, Keskinaslan A, Senocak M, TURNEP Study Group. Prevalence of peripheral neuropathy and painful peripheral neuropathy in Turkish diabetic patients. J Clin Neurophysiol. 2011;28:51-5.
    • (2011) J Clin Neurophysiol. , vol.28 , pp. 51-55
    • Erbas, T.1    Ertas, M.2    Yucel, A.3    Keskinaslan, A.4    Senocak, M.5
  • 42
    • 0028079577 scopus 로고
    • A prospective study of painful symptoms, small-fiber function and peripheral vascular disease in chronic painful diabetic neuropathy
    • 8181246 1:STN:280:DyaK2c3js12isQ%3D%3D
    • Benbow SJ, Chan AW, Bowsher D, MacFarlane IA, Williams G. A prospective study of painful symptoms, small-fiber function and peripheral vascular disease in chronic painful diabetic neuropathy. Diabet Med. 1994;11:17-21.
    • (1994) Diabet Med , vol.11 , pp. 17-21
    • Benbow, S.J.1    Chan, A.W.2    Bowsher, D.3    Macfarlane, I.A.4    Williams, G.5
  • 45
    • 34848902013 scopus 로고    scopus 로고
    • Does impaired glucose metabolism cause polyneuropathy? Review of previous studies and design of a prospective controlled population-based study
    • 17626290 1:CAS:528:DC%2BD2sXht1emu7bE
    • Dyck PJ, Klein CJ, Weigand SD. Does impaired glucose metabolism cause polyneuropathy? Review of previous studies and design of a prospective controlled population-based study. Muscle Nerve. 2007;36:536-41.
    • (2007) Muscle Nerve , vol.36 , pp. 536-541
    • Dyck, P.J.1    Klein, C.J.2    Weigand, S.D.3
  • 46
    • 84865609605 scopus 로고    scopus 로고
    • Prediabetic neuropathy: Does it exist?
    • 22562652 This paper reviews available findings on epidemiological, clinical, and pathogenetic aspects of peripheral and autonomic prediabetic neuropathy
    • • Papanas N, Ziegler D. Prediabetic neuropathy: does it exist? Curr Diab Rep. 2012;12:376-83. This paper reviews available findings on epidemiological, clinical, and pathogenetic aspects of peripheral and autonomic prediabetic neuropathy.
    • (2012) Curr Diab Rep , vol.12 , pp. 376-383
    • Papanas, N.1    Ziegler, D.2
  • 48
    • 50049112698 scopus 로고    scopus 로고
    • Idiopathic neuropathy patients are at high risk for metabolic syndrome
    • 18606421
    • Smith AG, Rose K, Singleton JR. Idiopathic neuropathy patients are at high risk for metabolic syndrome. J Neurol Sci. 2008;273:25-8.
    • (2008) J Neurol Sci , vol.273 , pp. 25-28
    • Smith, A.G.1    Rose, K.2    Singleton, J.R.3
  • 49
    • 54949157826 scopus 로고    scopus 로고
    • Mechanisms of disease: The oxidative stress theory of diabetic neuropathy
    • 18709457 1:CAS:528:DC%2BD1cXht1yrurrO
    • Figueroa-Romero C, Sadidi M, Feldman EL. Mechanisms of disease: the oxidative stress theory of diabetic neuropathy. Rev Endocr Metab Disord. 2008;9:301-14.
    • (2008) Rev Endocr Metab Disord , vol.9 , pp. 301-314
    • Figueroa-Romero, C.1    Sadidi, M.2    Feldman, E.L.3
  • 50
    • 38949112858 scopus 로고    scopus 로고
    • Pro-inflammatory mechanisms in diabetic neuropathy: Focus on the nuclear factor kappa B pathway
    • 18220713 1:CAS:528:DC%2BD1cXisFSnsbg%3D
    • Cameron NE, Cotter MA. Pro-inflammatory mechanisms in diabetic neuropathy: focus on the nuclear factor kappa B pathway. Curr Drug Targets. 2008;9:60-7.
    • (2008) Curr Drug Targets , vol.9 , pp. 60-67
    • Cameron, N.E.1    Cotter, M.A.2
  • 51
    • 70350188297 scopus 로고    scopus 로고
    • Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome
    • 19682539 1:CAS:528:DC%2BD1MXhtlWhtr%2FJ
    • Maury E, Brichard SM. Adipokine dysregulation, adipose tissue inflammation and metabolic syndrome. Mol Cell Endocrinol. 2010;314:1-16.
    • (2010) Mol Cell Endocrinol , vol.314 , pp. 1-16
    • Maury, E.1    Brichard, S.M.2
  • 52
    • 84858284386 scopus 로고    scopus 로고
    • Prevalence and comorbidity of chronic pain in the German general population
    • 22265888
    • Ohayon MM, Stingl JC. Prevalence and comorbidity of chronic pain in the German general population. J Psychiatr Res. 2012;46:444-50.
    • (2012) J Psychiatr Res , vol.46 , pp. 444-450
    • Ohayon, M.M.1    Stingl, J.C.2
  • 53
    • 34547692894 scopus 로고    scopus 로고
    • Pathology and pathogenetic mechanisms of diabetic neuropathy: Correlation with clinical signs and symptoms
    • 17462777 1:CAS:528:DC%2BD2sXovFeisLg%3D
    • Yagihashi S, Yamagishi S, Wada R. Pathology and pathogenetic mechanisms of diabetic neuropathy: correlation with clinical signs and symptoms. Diabetes Res Clin Pract. 2007;77:S184-9.
    • (2007) Diabetes Res Clin Pract , vol.77 , pp. 184-189
    • Yagihashi, S.1    Yamagishi, S.2    Wada, R.3
  • 54
    • 0020617677 scopus 로고
    • The natural history of painful diabetic neuropathy: A 4-year study
    • 1:STN:280:DyaL2c%2Fkt1Wrsg%3D%3D
    • Boulton AJM, Armstrong WD, Scarpello JHB, Ward JD. The natural history of painful diabetic neuropathy: a 4-year study. Postgr Med J. 1983;59:556-9.
    • (1983) Postgr Med J , vol.59 , pp. 556-559
    • Boulton, A.J.M.1    Armstrong, W.D.2    Scarpello, J.H.B.3    Ward, J.D.4
  • 55
    • 0033988613 scopus 로고    scopus 로고
    • Painful diabetic polyneuropathy: Epidemiology, pain description, and quality of life
    • 10670912 1:STN:280:DC%2BD3c7jsVeksA%3D%3D
    • Galer BS, Gianas A, Jensen MP. Painful diabetic polyneuropathy: epidemiology, pain description, and quality of life. Diabetes Res Clin Pract. 2000;47:123-8.
    • (2000) Diabetes Res Clin Pract , vol.47 , pp. 123-128
    • Galer, B.S.1    Gianas, A.2    Jensen, M.P.3
  • 56
    • 0027178952 scopus 로고
    • Painful neuropathy and foot ulceration in diabetic patients
    • 8375249 1:STN:280:DyaK3szoslSqsA%3D%3D
    • Veves A, Manes C, Murray HJ, Young MJ, Boulton AJ. Painful neuropathy and foot ulceration in diabetic patients. Diabetes Care. 1993;16:1187-9.
    • (1993) Diabetes Care , vol.16 , pp. 1187-1189
    • Veves, A.1    Manes, C.2    Murray, H.J.3    Young, M.J.4    Boulton, A.J.5
  • 57
    • 0020076117 scopus 로고
    • The diabetic leg
    • 7042425 1:STN:280:DyaL387oslKmsg%3D%3D
    • Ward JD. The diabetic leg. Diabetologia. 1982;22:141-7.
    • (1982) Diabetologia , vol.22 , pp. 141-147
    • Ward, J.D.1
  • 58
    • 0028087682 scopus 로고
    • Differences in peripheral and autonomic nerve function measurements in painful and painless neuropathy. A clinical study
    • 7821144 1:STN:280:DyaK2M7itFWgsg%3D%3D
    • Veves A, Young MJ, Manes C, Boulton AJ. Differences in peripheral and autonomic nerve function measurements in painful and painless neuropathy. A clinical study. Diabetes Care. 1994;17:1200-2.
    • (1994) Diabetes Care , vol.17 , pp. 1200-1202
    • Veves, A.1    Young, M.J.2    Manes, C.3    Boulton, A.J.4
  • 59
    • 84855907683 scopus 로고    scopus 로고
    • Distal symmetric polyneuropathy in diabetes. Differences between patients with and without neuropathic pain
    • 21915817 1:CAS:528:DC%2BC38XivFWhsL4%3D
    • Mondelli M, Aretini A, Baldasseroni A. Distal symmetric polyneuropathy in diabetes. Differences between patients with and without neuropathic pain. Exp Clin Endocrinol Diabetes. 2012;120:45-50.
    • (2012) Exp Clin Endocrinol Diabetes , vol.120 , pp. 45-50
    • Mondelli, M.1    Aretini, A.2    Baldasseroni, A.3
  • 60
    • 84865577636 scopus 로고    scopus 로고
    • Neuropathic pain: Is quantitative sensory testing helpful?
    • 22623149
    • Krumova EK, Geber C, Westermann A, Maier C. Neuropathic pain: is quantitative sensory testing helpful? Curr Diab Rep. 2012;12:393-402.
    • (2012) Curr Diab Rep , vol.12 , pp. 393-402
    • Krumova, E.K.1    Geber, C.2    Westermann, A.3    Maier, C.4
  • 61
    • 0026553092 scopus 로고
    • Discrimination between painful and painless diabetic neuropathy based on testing of large somatic nerve and sympathetic nerve function
    • 1600708 1:STN:280:DyaK383ovFWqtQ%3D%3D
    • Tsigos C, White A, Young RJ. Discrimination between painful and painless diabetic neuropathy based on testing of large somatic nerve and sympathetic nerve function. Diabet Med. 1992;9:359-65.
    • (1992) Diabet Med , vol.9 , pp. 359-365
    • Tsigos, C.1    White, A.2    Young, R.J.3
  • 62
    • 4644337721 scopus 로고    scopus 로고
    • Thermal thresholds predict painfulness of diabetic neuropathies
    • 15451905
    • Krämer HH, Rolke R, Bickel A, Birklein F. Thermal thresholds predict painfulness of diabetic neuropathies. Diabetes Care. 2004;27:2386-91.
    • (2004) Diabetes Care , vol.27 , pp. 2386-2391
    • Krämer, H.H.1    Rolke, R.2    Bickel, A.3    Birklein, F.4
  • 63
    • 0036199585 scopus 로고    scopus 로고
    • Painful polyneuropathy in patients with and without diabetes: Clinical, neurophysiologic, and quantitative sensory characteristics
    • 11882776
    • Vrethem M, Boivie J, Arnqvist H, Holmgren H, Lindström T. Painful polyneuropathy in patients with and without diabetes: clinical, neurophysiologic, and quantitative sensory characteristics. Clin J Pain. 2002;18:122-7.
    • (2002) Clin J Pain , vol.18 , pp. 122-127
    • Vrethem, M.1    Boivie, J.2    Arnqvist, H.3    Holmgren, H.4    Lindström, T.5
  • 64
    • 84865604470 scopus 로고    scopus 로고
    • Small fiber neuropathy: Is skin biopsy the holy grail?
    • 22570215 This paper is a comprehensive review on contemporary issues in small fiber neuropathy
    • • Lauria G, Lombardi R. Small fiber neuropathy: is skin biopsy the holy grail? Curr Diab Rep. 2012;12:384-92. This paper is a comprehensive review on contemporary issues in small fiber neuropathy.
    • (2012) Curr Diab Rep , vol.12 , pp. 384-392
    • Lauria, G.1    Lombardi, R.2
  • 65
    • 33746351504 scopus 로고    scopus 로고
    • The relationship among pain, sensory loss, and small nerve fibers in diabetes
    • 16567832
    • Sorensen L, Molyneaux L, Yue DK. The relationship among pain, sensory loss, and small nerve fibers in diabetes. Diabetes Care. 2006;29:883-7.
    • (2006) Diabetes Care , vol.29 , pp. 883-887
    • Sorensen, L.1    Molyneaux, L.2    Yue, D.K.3
  • 66
    • 34547589982 scopus 로고    scopus 로고
    • Surrogate markers of small fiber damage in human diabetic neuropathy
    • 17513704 1:CAS:528:DC%2BD2sXos12qsbw%3D
    • Quattrini C, Tavakoli M, Jeziorska M, Kallinikos P, Tesfaye S, Finnigan J, et al. Surrogate markers of small fiber damage in human diabetic neuropathy. Diabetes. 2007;56:2148-54.
    • (2007) Diabetes , vol.56 , pp. 2148-2154
    • Quattrini, C.1    Tavakoli, M.2    Jeziorska, M.3    Kallinikos, P.4    Tesfaye, S.5    Finnigan, J.6
  • 67
    • 46849105270 scopus 로고    scopus 로고
    • The diagnostic criteria for small fiber neuropathy: From symptoms to neuropathology
    • 18524793
    • Devigili G, Tugnoli V, Penza P, Camozzi F, Lombardi R, Melli G, et al. The diagnostic criteria for small fiber neuropathy: from symptoms to neuropathology. Brain. 2008;131:1912-25.
    • (2008) Brain , vol.131 , pp. 1912-1925
    • Devigili, G.1    Tugnoli, V.2    Penza, P.3    Camozzi, F.4    Lombardi, R.5    Melli, G.6
  • 68
    • 67649224880 scopus 로고    scopus 로고
    • Painful or painless lower limb dysesthesias are highly predictive of peripheral neuropathy: Comparison of different diagnostic modalities
    • 18789872
    • Scherens A, Maier C, Haussleiter IS, Schwenkreis P, Vlckova-Moravcova E, Baron R, et al. Painful or painless lower limb dysesthesias are highly predictive of peripheral neuropathy: comparison of different diagnostic modalities. Eur J Pain. 2009;13:711-8.
    • (2009) Eur J Pain , vol.13 , pp. 711-718
    • Scherens, A.1    Maier, C.2    Haussleiter, I.S.3    Schwenkreis, P.4    Vlckova-Moravcova, E.5    Baron, R.6
  • 69
    • 0021036313 scopus 로고
    • Progressive centripetal degeneration of axons in small fiber diabetic polyneuropathy
    • 6652463
    • Said G, Slama G, Selva J. Progressive centripetal degeneration of axons in small fiber diabetic polyneuropathy. Brain. 1983;106:791-807.
    • (1983) Brain , vol.106 , pp. 791-807
    • Said, G.1    Slama, G.2    Selva, J.3
  • 70
    • 0033914569 scopus 로고    scopus 로고
    • Dissociated sensory loss in diabetic autonomic neuropathy
    • 10975215 1:STN:280:DC%2BD3M%2FmsF2nsg%3D%3D
    • Winkler AS, Ejskjaer N, Edmonds M, Watkins PJ. Dissociated sensory loss in diabetic autonomic neuropathy. Diabet Med. 2000;17:457-62.
    • (2000) Diabet Med , vol.17 , pp. 457-462
    • Winkler, A.S.1    Ejskjaer, N.2    Edmonds, M.3    Watkins, P.J.4
  • 71
    • 84863601822 scopus 로고    scopus 로고
    • Thermal threshold: Research study on small fiber dysfunction in distal diabetic polyneuropathy
    • Jimenez-Cohl P, Grekin C, Leyton C, Vargas C, Villaseca R. Thermal threshold: research study on small fiber dysfunction in distal diabetic polyneuropathy. J Diabetes Sci Technol. 2012;6:177-83.
    • (2012) J Diabetes Sci Technol. , vol.6 , pp. 177-183
    • Jimenez-Cohl, P.1    Grekin, C.2    Leyton, C.3    Vargas, C.4    Villaseca, R.5
  • 72
    • 0023807691 scopus 로고
    • Evaluation of thermal, pain, and vibration sensation thresholds in newly diagnosed type 1 diabetic patients
    • 3236020 1:STN:280:DyaL1M7nslaqtA%3D%3D
    • Ziegler D, Mayer P, Gries FA. Evaluation of thermal, pain, and vibration sensation thresholds in newly diagnosed type 1 diabetic patients. J Neurol Neurosurg Psychiatry. 1988;51:1420-4.
    • (1988) J Neurol Neurosurg Psychiatry , vol.51 , pp. 1420-1424
    • Ziegler, D.1    Mayer, P.2    Gries, F.A.3
  • 73
    • 0034079572 scopus 로고    scopus 로고
    • Patterns of quantitative sensation testing of hypoesthesia and hyperalgesia are predictive of diabetic polyneuropathy: A study of 3 cohorts
    • 10857944 1:STN:280:DC%2BD3cvntFylsA%3D%3D
    • Dyck PJ, Dyck PJ, Larson TS, O'Brien PC, Velosa JA. Patterns of quantitative sensation testing of hypoesthesia and hyperalgesia are predictive of diabetic polyneuropathy: a study of 3 cohorts. Diabetes Care. 2000;23:510-7.
    • (2000) Diabetes Care , vol.23 , pp. 510-517
    • Dyck, P.J.1    Dyck, P.J.2    Larson, T.S.3    O'Brien, P.C.4    Velosa, J.A.5
  • 74
    • 3042753117 scopus 로고    scopus 로고
    • Cooling detection thresholds in the assessment of diabetic sensory polyneuropathy: Comparison of CASE IV and Medoc instruments
    • 15220245
    • Zinman LH, Bril V, Perkins BA. Cooling detection thresholds in the assessment of diabetic sensory polyneuropathy: comparison of CASE IV and Medoc instruments. Diabetes Care. 2004;27:1674-9.
    • (2004) Diabetes Care , vol.27 , pp. 1674-1679
    • Zinman, L.H.1    Bril, V.2    Perkins, B.A.3
  • 75
    • 44649124932 scopus 로고    scopus 로고
    • Small-fiber involvement in diabetic patients with neuropathic foot pain
    • 18544107 1:STN:280:DC%2BD1czns1ekuw%3D%3D
    • Vlckova-Moravcova E, Bednarik J, Belobradkova J, Sommer C. Small-fiber involvement in diabetic patients with neuropathic foot pain. Diabet Med. 2008;25:692-9.
    • (2008) Diabet Med , vol.25 , pp. 692-699
    • Vlckova-Moravcova, E.1    Bednarik, J.2    Belobradkova, J.3    Sommer, C.4
  • 76
    • 34247595845 scopus 로고    scopus 로고
    • Intraepidermal nerve fiber density as a marker of early diabetic neuropathy
    • 17221881 1:STN:280:DC%2BD2s3pvFahsA%3D%3D
    • Umapathi T, Tan WL, Loke SC, Soon PC, Tavintharan S, Chan YH. Intraepidermal nerve fiber density as a marker of early diabetic neuropathy. Muscle Nerve. 2007;35:591-8.
    • (2007) Muscle Nerve , vol.35 , pp. 591-598
    • Umapathi, T.1    Tan, W.L.2    Loke, S.C.3    Soon, P.C.4    Tavintharan, S.5    Chan, Y.H.6
  • 77
    • 80054720121 scopus 로고    scopus 로고
    • Asymptomatic small fiber neuropathy in diabetes mellitus: Investigations with intraepidermal nerve fiber density, quantitative sensory testing and laser-evoked potentials
    • 21472496
    • Ragé M, Van Acker N, Knaapen MW, Timmers M, Streffer J, Hermans MP, et al. Asymptomatic small fiber neuropathy in diabetes mellitus: investigations with intraepidermal nerve fiber density, quantitative sensory testing and laser-evoked potentials. J Neurol. 2011;258:1852-64.
    • (2011) J Neurol , vol.258 , pp. 1852-1864
    • Ragé, M.1    Van Acker, N.2    Knaapen, M.W.3    Timmers, M.4    Streffer, J.5    Hermans, M.P.6
  • 78
    • 77950421254 scopus 로고    scopus 로고
    • Polyneuropathy in type and type 2 diabetes: Comparison of nerve conduction studies, thermal perception thresholds and intraepidermal nerve fiber densities
    • 19943330
    • Løseth S, Mellgren SI, Jorde R, Lindal S, Stålberg E. Polyneuropathy in type and type 2 diabetes: comparison of nerve conduction studies, thermal perception thresholds and intraepidermal nerve fiber densities. Diabetes Metab Res Rev. 2010;26:100-6.
    • (2010) Diabetes Metab Res Rev , vol.26 , pp. 100-106
    • Løseth, S.1    Mellgren, S.I.2    Jorde, R.3    Lindal, S.4    Stålberg, E.5
  • 79
    • 64549133474 scopus 로고    scopus 로고
    • Noninvasive evaluation of neural impairment in subjects with impaired glucose tolerance
    • 18835942
    • Putz Z, Tabák AG, Tóth N, Istenes I, Németh N, Gandhi RA, et al. Noninvasive evaluation of neural impairment in subjects with impaired glucose tolerance. Diabetes Care. 2009;32:181-3.
    • (2009) Diabetes Care , vol.32 , pp. 181-183
    • Putz, Z.1    Tabák, A.G.2    Tóth, N.3    Istenes, I.4    Németh, N.5    Gandhi, R.A.6
  • 80
    • 0033959184 scopus 로고    scopus 로고
    • Density of sympathetic axons in sural nerve biopsies of neuropathy patients is related to painfulness
    • 10666548 1:STN:280:DC%2BD3c7jtlSrsA%3D%3D
    • Bickel A, Butz M, Schmelz M, Handwerker HO, Neundörfer B. Density of sympathetic axons in sural nerve biopsies of neuropathy patients is related to painfulness. Pain. 2000;84:413-9.
    • (2000) Pain , vol.84 , pp. 413-419
    • Bickel, A.1    Butz, M.2    Schmelz, M.3    Handwerker, H.O.4    Neundörfer, B.5
  • 81
    • 0036895709 scopus 로고    scopus 로고
    • Local sympathetic denervation in painful diabetic neuropathy
    • 12453912 1:CAS:528:DC%2BD38Xptl2nu7Y%3D
    • Tack CJ, van Gurp PJ, Holmes C, Goldstein DS. Local sympathetic denervation in painful diabetic neuropathy. Diabetes. 2002;51:3545-53.
    • (2002) Diabetes , vol.51 , pp. 3545-3553
    • Tack, C.J.1    Van Gurp, P.J.2    Holmes, C.3    Goldstein, D.S.4
  • 82
    • 77951730299 scopus 로고    scopus 로고
    • Treatment-induced diabetic neuropathy: A reversible painful autonomic neuropathy
    • 20437589 The largest case series and first detailed analysis of acute neuropathies associated with glycemic control
    • • Gibbons CH, Freeman R. Treatment-induced diabetic neuropathy: a reversible painful autonomic neuropathy. Ann Neurol. 2010;67:534-41. The largest case series and first detailed analysis of acute neuropathies associated with glycemic control.
    • (2010) Ann Neurol , vol.67 , pp. 534-541
    • Gibbons, C.H.1    Freeman, R.2
  • 84
    • 1342309501 scopus 로고    scopus 로고
    • Prospective evaluation of somatic and autonomic small fibers in selected autonomic neuropathies
    • 14981179 1:STN:280:DC%2BD2c%2FptFOgtg%3D%3D
    • Singer W, Spies JM, McArthur J, et al. Prospective evaluation of somatic and autonomic small fibers in selected autonomic neuropathies. Neurology. 2004;62:612-8.
    • (2004) Neurology , vol.62 , pp. 612-618
    • Singer, W.1    Spies, J.M.2    McArthur, J.3
  • 85
    • 0022607854 scopus 로고
    • Variable relationship between peripheral somatic and autonomic neuropathy in patients with different syndromes of diabetic polyneuropathy
    • 3002887 1:STN:280:DyaL287gvFWqtA%3D%3D
    • Young RJ, Zhou YQ, Rodriguez E, Prescott RJ, Ewing DJ, Clarke BF. Variable relationship between peripheral somatic and autonomic neuropathy in patients with different syndromes of diabetic polyneuropathy. Diabetes. 1986;35:192-7.
    • (1986) Diabetes , vol.35 , pp. 192-197
    • Young, R.J.1    Zhou, Y.Q.2    Rodriguez, E.3    Prescott, R.J.4    Ewing, D.J.5    Clarke, B.F.6
  • 86
    • 77958172304 scopus 로고    scopus 로고
    • Painful diabetic neuropathy is associated with greater autonomic dysfunction than painless diabetic neuropathy
    • 20587724
    • Gandhi RA, Marques JL, Selvarajah D, Emery CJ, Tesfaye S. Painful diabetic neuropathy is associated with greater autonomic dysfunction than painless diabetic neuropathy. Diabetes Care. 2010;33:1585-90.
    • (2010) Diabetes Care , vol.33 , pp. 1585-1590
    • Gandhi, R.A.1    Marques, J.L.2    Selvarajah, D.3    Emery, C.J.4    Tesfaye, S.5
  • 87
    • 79959373944 scopus 로고    scopus 로고
    • Autonomic pain responses during sleep: A study of heart rate variability
    • 21216165 1:STN:280:DC%2BC3Mnit1OrsQ%3D%3D
    • Chouchou F, Pichot V, Perchet C, Legrain V, Garcia-Larrea L, Roche F, et al. Autonomic pain responses during sleep: a study of heart rate variability. Eur J Pain. 2011;15:554-60.
    • (2011) Eur J Pain , vol.15 , pp. 554-560
    • Chouchou, F.1    Pichot, V.2    Perchet, C.3    Legrain, V.4    Garcia-Larrea, L.5    Roche, F.6
  • 89
    • 0032771801 scopus 로고    scopus 로고
    • Relief of chronic pain may be accompanied by an increase in a measure of heart rate variability
    • 10439764 1:STN:280:DyaK1MzmvVKgtQ%3D%3D
    • Storella RJ, Shi Y, O'Connor DM, Pharo GH, Abrams JT, Levitt J. Relief of chronic pain may be accompanied by an increase in a measure of heart rate variability. Anesth Analg. 1999;89:448-50.
    • (1999) Anesth Analg , vol.89 , pp. 448-450
    • Storella, R.J.1    Shi, Y.2    O'Connor, D.M.3    Pharo, G.H.4    Abrams, J.T.5    Levitt, J.6
  • 90
    • 0033053523 scopus 로고    scopus 로고
    • Painful and painless peripheral sensory neuropathies due to HIV infection: A comparison using quantitative sensory evaluation
    • 10204739 1:STN:280:DyaK1M3hvFCgsQ%3D%3D
    • Bouhassira D, Attal N, Willer JC, Brasseur L. Painful and painless peripheral sensory neuropathies due to HIV infection: a comparison using quantitative sensory evaluation. Pain. 1999;80:265-72.
    • (1999) Pain , vol.80 , pp. 265-272
    • Bouhassira, D.1    Attal, N.2    Willer, J.C.3    Brasseur, L.4
  • 91
    • 0026504343 scopus 로고
    • Acute and remitting painful diabetic polyneuropathy: A comparison of peripheral nerve fiber pathology
    • 1594258 1:STN:280:DyaK383nvVOruw%3D%3D
    • Britland ST, Young RJ, Sharma AK, Clarke BF. Acute and remitting painful diabetic polyneuropathy: a comparison of peripheral nerve fiber pathology. Pain. 1992;48:361-70.
    • (1992) Pain , vol.48 , pp. 361-370
    • Britland, S.T.1    Young, R.J.2    Sharma, A.K.3    Clarke, B.F.4
  • 92
    • 20044379339 scopus 로고    scopus 로고
    • Diabetic sensorimotor neuropathy: Treatment
    • F.A. Gries N.E. Cameron A. Low D. Ziegler (eds) Thieme Stuttgard
    • Thomas PK. Diabetic sensorimotor neuropathy: treatment. In: Gries FA, Cameron NE, Low PA, Ziegler D, editors. Textbook of diabetic neuropathy. Stuttgard: Thieme; 2003. p. 208-11.
    • (2003) Textbook of Diabetic Neuropathy , pp. 208-211
    • Thomas, P.K.1
  • 93
    • 0025794002 scopus 로고
    • Sural nerve morphometry in diabetic autonomic and painful sensory neuropathy: A clinico pathological study
    • 2043955
    • Llewelyn JG, Gilbey SG, Thomas PK, King RH, Muddle JR, Watkins PJ. Sural nerve morphometry in diabetic autonomic and painful sensory neuropathy: a clinico pathological study. Brain. 1991;114:867-92.
    • (1991) Brain , vol.114 , pp. 867-892
    • Llewelyn, J.G.1    Gilbey, S.G.2    Thomas, P.K.3    King, R.H.4    Muddle, J.R.5    Watkins, P.J.6
  • 94
    • 0035035118 scopus 로고    scopus 로고
    • Sural nerve fiber pathology in diabetic patients with mild neuropathy: Relationship to pain, quantitative sensory testing and peripheral nerve electrophysiology
    • 11355308 1:STN:280:DC%2BD3M3mtlemuw%3D%3D
    • Malik RA, Veves A, Walker D, Siddique I, Lye RH, Schady W, et al. Sural nerve fiber pathology in diabetic patients with mild neuropathy: relationship to pain, quantitative sensory testing and peripheral nerve electrophysiology. Acta Neuropathol. 2001;101:367-74.
    • (2001) Acta Neuropathol , vol.101 , pp. 367-374
    • Malik, R.A.1    Veves, A.2    Walker, D.3    Siddique, I.4    Lye, R.H.5    Schady, W.6
  • 95
    • 84861213330 scopus 로고    scopus 로고
    • Assessing corneal nerve structure and function in diabetic neuropathy
    • 22594548
    • Tavakoli M, Petropoulos IN, Malik RA. Assessing corneal nerve structure and function in diabetic neuropathy. Clin Exp Optom. 2012;95:338-47.
    • (2012) Clin Exp Optom , vol.95 , pp. 338-347
    • Tavakoli, M.1    Petropoulos, I.N.2    Malik, R.A.3
  • 96
    • 0021715825 scopus 로고
    • Blood flow patterns in painful diabetic neuropathy
    • 6530051 1:STN:280:DyaL2M7lsFSgtA%3D%3D
    • Archer AG, Roberts VC, Watkins PJ. Blood flow patterns in painful diabetic neuropathy. Diabetologia. 1984;27:563-7.
    • (1984) Diabetologia , vol.27 , pp. 563-567
    • Archer, A.G.1    Roberts, V.C.2    Watkins, P.J.3
  • 97
    • 0042071581 scopus 로고    scopus 로고
    • Increased sural nerve epineurial blood flow in human subjects with painful diabetic neuropathy
    • 12819899 1:STN:280:DC%2BD3szmtlShtg%3D%3D
    • Eaton SE, Harris ND, Ibrahim S, Patel KA, Selmi F, Radatz M, et al. Increased sural nerve epineurial blood flow in human subjects with painful diabetic neuropathy. Diabetologia. 2003;46:934-9.
    • (2003) Diabetologia , vol.46 , pp. 934-939
    • Eaton, S.E.1    Harris, N.D.2    Ibrahim, S.3    Patel, K.A.4    Selmi, F.5    Radatz, M.6
  • 98
    • 20144389036 scopus 로고    scopus 로고
    • Sural nerve pathology in diabetic patients with minimal but progressive neuropathy
    • 15729579 1:CAS:528:DC%2BD2MXisVCitbs%3D
    • Malik RA, Tesfaye S, Newrick PG, Walker D, Rajbhandari SM, Siddique I, et al. Sural nerve pathology in diabetic patients with minimal but progressive neuropathy. Diabetologia. 2005;48:578-85.
    • (2005) Diabetologia , vol.48 , pp. 578-585
    • Malik, R.A.1    Tesfaye, S.2    Newrick, P.G.3    Walker, D.4    Rajbhandari, S.M.5    Siddique, I.6
  • 99
    • 84856201567 scopus 로고    scopus 로고
    • Advances in the epidemiology, pathogenesis and management of diabetic peripheral neuropathy
    • Tesfaye S, Selvarajah D. Advances in the epidemiology, pathogenesis and management of diabetic peripheral neuropathy. Diabetes Metab Res Rev. 2012;1:8-14.
    • (2012) Diabetes Metab Res Rev , vol.1 , pp. 8-14
    • Tesfaye, S.1    Selvarajah, D.2
  • 100
    • 33847660152 scopus 로고    scopus 로고
    • Impaired skin microvascular reactivity in painful diabetic neuropathy
    • 17327336
    • Quattrini C, Harris ND, Malik RA, Tesfaye S. Impaired skin microvascular reactivity in painful diabetic neuropathy. Diabetes Care. 2007;30:655-9.
    • (2007) Diabetes Care , vol.30 , pp. 655-659
    • Quattrini, C.1    Harris, N.D.2    Malik, R.A.3    Tesfaye, S.4
  • 101
    • 66749176147 scopus 로고    scopus 로고
    • Microvascular reactivity and inflammatory cytokines in painful and painless peripheral diabetic neuropathy
    • 19276232 1:CAS:528:DC%2BD1MXntFGmtLY%3D
    • Doupis J, Lyons TE, Wu S, Dinh T, Veves A. Microvascular reactivity and inflammatory cytokines in painful and painless peripheral diabetic neuropathy. J Clin Endocrinol Metab. 2009;94:2157-63.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 2157-2163
    • Doupis, J.1    Lyons, T.E.2    Wu, S.3    Dinh, T.4    Veves, A.5
  • 102
    • 0036781580 scopus 로고    scopus 로고
    • Treatment of chronic painful diabetic neuropathy with isosorbide dinitrate spray: A double-blind placebo-controlled cross-over study
    • 12351464 1:CAS:528:DC%2BD38Xos1Whtro%3D
    • Yuen KC, Baker NR, Rayman G. Treatment of chronic painful diabetic neuropathy with isosorbide dinitrate spray: a double-blind placebo-controlled cross-over study. Diabetes Care. 2002;25:1699-703.
    • (2002) Diabetes Care , vol.25 , pp. 1699-1703
    • Yuen, K.C.1    Baker, N.R.2    Rayman, G.3
  • 103
    • 0042323109 scopus 로고    scopus 로고
    • Glyceryl trinitrate patches as an alternative to isosorbide dinitrate spray in the treatment of chronic painful diabetic neuropathy
    • 12941745
    • Rayman G, Baker NR, Krishnan ST. Glyceryl trinitrate patches as an alternative to isosorbide dinitrate spray in the treatment of chronic painful diabetic neuropathy. Diabetes Care. 2003;26:2697-8.
    • (2003) Diabetes Care , vol.26 , pp. 2697-2698
    • Rayman, G.1    Baker, N.R.2    Krishnan, S.T.3
  • 104
    • 67651048942 scopus 로고    scopus 로고
    • Neuropathic pain: A maladaptive response of the nervous system to damage
    • 19400724 1:CAS:528:DC%2BD1MXpsV2nur8%3D
    • Costigan M, Scholz J, Woolf CJ. Neuropathic pain: a maladaptive response of the nervous system to damage. Annu Rev Neurosci. 2009;32:1-32.
    • (2009) Annu Rev Neurosci , vol.32 , pp. 1-32
    • Costigan, M.1    Scholz, J.2    Woolf, C.J.3
  • 105
    • 77955326429 scopus 로고    scopus 로고
    • Neuropathic pain: Diagnosis, pathophysiological mechanisms, and treatment
    • 20650402 This is a practical review on pathophysiology, diagnosis, sensory profile, and treatment of neuropathic pain
    • • Baron R, Binder A, Wasner G. Neuropathic pain: diagnosis, pathophysiological mechanisms, and treatment. Lancet Neurol. 2010;9:807-19. This is a practical review on pathophysiology, diagnosis, sensory profile, and treatment of neuropathic pain.
    • (2010) Lancet Neurol , vol.9 , pp. 807-819
    • Baron, R.1    Binder, A.2    Wasner, G.3
  • 106
    • 79957959515 scopus 로고    scopus 로고
    • Cellular and molecular insights into neuropathy-induced pain hypersensitivity for mechanism-based treatment approaches
    • 21440003 1:CAS:528:DC%2BC3MXntFGmsbY%3D This is an updated complete review of novel experimental treatment approaches to neuropathic pain, mainly acting on the spinal nociceptive network
    • • Berger JV, Knaepen L, Janssen SP, Jaken RJ, Marcus MA, Joosten EA, et al. Cellular and molecular insights into neuropathy-induced pain hypersensitivity for mechanism-based treatment approaches. Brain Res Rev. 2011;67:282-310. This is an updated complete review of novel experimental treatment approaches to neuropathic pain, mainly acting on the spinal nociceptive network.
    • (2011) Brain Res Rev , vol.67 , pp. 282-310
    • Berger, J.V.1    Knaepen, L.2    Janssen, S.P.3    Jaken, R.J.4    Marcus, M.A.5    Joosten, E.A.6
  • 107
    • 24344472656 scopus 로고    scopus 로고
    • Hyperexcitable polymodal and insensitive nociceptors in painful human neuropathy
    • 15973653
    • Ochoa JL, Campero M, Serra J, Bostock H. Hyperexcitable polymodal and insensitive nociceptors in painful human neuropathy. Muscle Nerve. 2005;32:459-72.
    • (2005) Muscle Nerve , vol.32 , pp. 459-472
    • Ochoa, J.L.1    Campero, M.2    Serra, J.3    Bostock, H.4
  • 109
    • 84155162846 scopus 로고    scopus 로고
    • Microneurographic identification of spontaneous activity in C-nociceptors in neuropathic pain states in humans and rats
    • 21993185 1:CAS:528:DC%2BC38XhtFShtQ%3D%3D
    • Serra J, Bostock H, Solà R, Aleu J, García E, Cokic B, et al. Microneurographic identification of spontaneous activity in C-nociceptors in neuropathic pain states in humans and rats. Pain. 2012;153:42-55.
    • (2012) Pain , vol.153 , pp. 42-55
    • Serra, J.1    Bostock, H.2    Solà, R.3    Aleu, J.4    García, E.5    Cokic, B.6
  • 110
    • 70349371112 scopus 로고    scopus 로고
    • A cross-sectional cohort survey in 2100 patients with painful diabetic neuropathy and postherpetic neuralgia: Differences in demographic data and sensory symptoms
    • 19592166
    • Baron R, Tölle TR, Gockel U, Brosz M, Freynhagen R. A cross-sectional cohort survey in 2100 patients with painful diabetic neuropathy and postherpetic neuralgia: differences in demographic data and sensory symptoms. Pain. 2009;146:34-40.
    • (2009) Pain , vol.146 , pp. 34-40
    • Baron, R.1    Tölle, T.R.2    Gockel, U.3    Brosz, M.4    Freynhagen, R.5
  • 112
    • 70349776079 scopus 로고    scopus 로고
    • Sensory profiles: A new strategy for selecting patients in treatment trials for neuropathic pain
    • 19625126 1:STN:280:DC%2BD1MnotFGrsQ%3D%3D
    • Cruccu G, Truini A. Sensory profiles: a new strategy for selecting patients in treatment trials for neuropathic pain. Pain. 2009;146:5-6.
    • (2009) Pain , vol.146 , pp. 5-6
    • Cruccu, G.1    Truini, A.2
  • 113
    • 77955575312 scopus 로고    scopus 로고
    • Mechanisms of pain in distal symmetric polyneuropathy: A combined clinical and neurophysiological study
    • 20598802 1:STN:280:DC%2BC3cjmsVSlsA%3D%3D
    • Truini A, Biasiotta A, La Cesa S, Di Stefano G, Galeotti F, Petrucci MT, et al. Mechanisms of pain in distal symmetric polyneuropathy: a combined clinical and neurophysiological study. Pain. 2010;150:516-21.
    • (2010) Pain , vol.150 , pp. 516-521
    • Truini, A.1    Biasiotta, A.2    La Cesa, S.3    Di Stefano, G.4    Galeotti, F.5    Petrucci, M.T.6
  • 114
    • 65349124102 scopus 로고    scopus 로고
    • Subclinical inflammation and diabetic polyneuropathy: MONICA/KORA Survey F3 (Augsburg, Germany)
    • 19131463
    • Herder C, Lankisch M, Ziegler D, Rathmann W, Koenig W, Illig T, et al. Subclinical inflammation and diabetic polyneuropathy: MONICA/KORA Survey F3 (Augsburg, Germany). Diabetes Care. 2009;32:680-2.
    • (2009) Diabetes Care , vol.32 , pp. 680-682
    • Herder, C.1    Lankisch, M.2    Ziegler, D.3    Rathmann, W.4    Koenig, W.5    Illig, T.6
  • 115
    • 32444451323 scopus 로고    scopus 로고
    • The role of neuroinflammation in neuropathic pain: Mechanisms and therapeutic targets
    • 16478686 1:CAS:528:DC%2BD28XhsFygsbk%3D
    • Myers RR, Campana WM, Shubayev VI. The role of neuroinflammation in neuropathic pain: mechanisms and therapeutic targets. Drug Discov Today. 2006;11:8-20.
    • (2006) Drug Discov Today , vol.11 , pp. 8-20
    • Myers, R.R.1    Campana, W.M.2    Shubayev, V.I.3
  • 116
    • 84862334333 scopus 로고    scopus 로고
    • The role of the immune system in the generation of neuropathic pain
    • 22710756 1:CAS:528:DC%2BC38XovVygsrs%3D This is an interesting review on the experimental and human studies showing a bi-directional signalling between sensory and the immune system in the neuropathic pain generation and maintenance
    • • Calvo M, Dawes JM, Bennett DL. The role of the immune system in the generation of neuropathic pain. Lancet Neurol. 2012;11:629-42. This is an interesting review on the experimental and human studies showing a bi-directional signalling between sensory and the immune system in the neuropathic pain generation and maintenance.
    • (2012) Lancet Neurol , vol.11 , pp. 629-642
    • Calvo, M.1    Dawes, J.M.2    Bennett, D.L.3
  • 117
    • 34347402769 scopus 로고    scopus 로고
    • Differential expression of cytokines in painful and painless neuropathies
    • 17606879
    • Uçeyler N, Rogausch JP, Toyka KV, Sommer C. Differential expression of cytokines in painful and painless neuropathies. Neurology. 2007;69:42-9.
    • (2007) Neurology , vol.69 , pp. 42-49
    • Uçeyler, N.1    Rogausch, J.P.2    Toyka, K.V.3    Sommer, C.4
  • 118
    • 84862300506 scopus 로고    scopus 로고
    • High TNF-alpha plasma levels and macrophages iNOS and TNF-alpha expression as risk factors for painful diabetic neuropathy
    • 21811392 1:CAS:528:DC%2BC3MXps1ChtLg%3D
    • Purwata TE. High TNF-alpha plasma levels and macrophages iNOS and TNF-alpha expression as risk factors for painful diabetic neuropathy. J Pain Res. 2011;4:169-75.
    • (2011) J Pain Res , vol.4 , pp. 169-175
    • Purwata, T.E.1
  • 119
    • 70349303776 scopus 로고    scopus 로고
    • Diabetic painful and insensate neuropathy: Pathogenesis and potential treatments
    • 19789069 1:CAS:528:DC%2BC3cXitVKqu74%3D
    • Obrosova IG. Diabetic painful and insensate neuropathy: pathogenesis and potential treatments. Neurotherapeutics. 2009;6:638-47.
    • (2009) Neurotherapeutics , vol.6 , pp. 638-647
    • Obrosova, I.G.1
  • 120
    • 77549084735 scopus 로고    scopus 로고
    • Abnormal calcium homeostasis in peripheral neuropathies
    • 20034667 1:CAS:528:DC%2BC3cXjtVSmsro%3D
    • Fernyhough P, Calcutt NA. Abnormal calcium homeostasis in peripheral neuropathies. Cell Calcium. 2010;47:130-9.
    • (2010) Cell Calcium , vol.47 , pp. 130-139
    • Fernyhough, P.1    Calcutt, N.A.2
  • 121
    • 75549088964 scopus 로고    scopus 로고
    • Shifting the disease management paradigm from glucose: What are the pros?
    • 19875579
    • Stirban A, Tschoepe D, Stratmann B. Shifting the disease management paradigm from glucose: what are the pros? Diabetes Care. 2009;32 Suppl 2:S349-52.
    • (2009) Diabetes Care , vol.32 , Issue.SUPPL. 2 , pp. 349-352
    • Stirban, A.1    Tschoepe, D.2    Stratmann, B.3
  • 122
    • 84862020461 scopus 로고    scopus 로고
    • Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy
    • 22581285 1:CAS:528:DC%2BC38XmvFChur0%3D This study shows a mechanism for hyperalgesia based on the glycolytic metabolite methylglyoxal. It introduces a previously undescribed pain mechanism and supports a concept of metabolically driven hyperalgesia in diabetes
    • •• Bierhaus A, Fleming T, Stoyanov S, Leffler A, Babes A, Neacsu C, et al. Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy. Nat Med. 2012;18:926-33. This study shows a mechanism for hyperalgesia based on the glycolytic metabolite methylglyoxal. It introduces a previously undescribed pain mechanism and supports a concept of metabolically driven hyperalgesia in diabetes.
    • (2012) Nat Med , vol.18 , pp. 926-933
    • Bierhaus, A.1    Fleming, T.2    Stoyanov, S.3    Leffler, A.4    Babes, A.5    Neacsu, C.6
  • 123
    • 84868550464 scopus 로고    scopus 로고
    • Glyoxalase 1 and glyoxalase 2 activities in blood and neuronal tissue samples from experimental animal models of obesity and type 2 diabetes mellitus
    • 22893478 1:CAS:528:DC%2BC38Xhs1Wlu7%2FN
    • Skapare E, Konrade I, Liepinsh E, Makrecka M, Zvejniece L, Svalbe B, et al. Glyoxalase 1 and glyoxalase 2 activities in blood and neuronal tissue samples from experimental animal models of obesity and type 2 diabetes mellitus. J Physiol Sci. 2012;62:469-78.
    • (2012) J Physiol Sci , vol.62 , pp. 469-478
    • Skapare, E.1    Konrade, I.2    Liepinsh, E.3    Makrecka, M.4    Zvejniece, L.5    Svalbe, B.6
  • 126
    • 53549113319 scopus 로고    scopus 로고
    • Thalamic neuronal dysfunction and chronic sensorimotor distal symmetrical polyneuropathy in patients with type 1 diabetes mellitus
    • 18773192 1:CAS:528:DC%2BD1cXht1amsrbO
    • Selvarajah D, Wilkinson ID, Emery CJ, Shaw PJ, Griffiths PD, Gandhi R, et al. Thalamic neuronal dysfunction and chronic sensorimotor distal symmetrical polyneuropathy in patients with type 1 diabetes mellitus. Diabetologia. 2008;51:2088-92.
    • (2008) Diabetologia , vol.51 , pp. 2088-2092
    • Selvarajah, D.1    Wilkinson, I.D.2    Emery, C.J.3    Shaw, P.J.4    Griffiths, P.D.5    Gandhi, R.6
  • 127
    • 48649099790 scopus 로고    scopus 로고
    • Differences in metabolites in pain-processing brain regions in patients with diabetes and painful neuropathy
    • 18299445
    • Sorensen L, Siddall PJ, Trenell MI, Yue DK. Differences in metabolites in pain-processing brain regions in patients with diabetes and painful neuropathy. Diabetes Care. 2008;31:980-1.
    • (2008) Diabetes Care , vol.31 , pp. 980-981
    • Sorensen, L.1    Siddall, P.J.2    Trenell, M.I.3    Yue, D.K.4
  • 128
    • 79956081698 scopus 로고    scopus 로고
    • Microvascular perfusion abnormalities of the Thalamus in painful but not painless diabetic polyneuropathy: A clue to the pathogenesis of pain in type 1 diabetes
    • 21282344
    • Selvarajah D, Wilkinson ID, Gandhi R, Griffiths PD, Tesfaye S. Microvascular perfusion abnormalities of the Thalamus in painful but not painless diabetic polyneuropathy: a clue to the pathogenesis of pain in type 1 diabetes. Diabetes Care. 2011;34:718-20.
    • (2011) Diabetes Care , vol.34 , pp. 718-720
    • Selvarajah, D.1    Wilkinson, I.D.2    Gandhi, R.3    Griffiths, P.D.4    Tesfaye, S.5
  • 130
    • 80051594325 scopus 로고    scopus 로고
    • Central nervous system involvement in diabetic neuropathy
    • This paper reviews the findings on central mechanisms of neuropathic pain in diabetes
    • • Selvarajah D, Wilkinson ID, Davies J, Gandhi R, Tesfaye S. Central nervous system involvement in diabetic neuropathy. Curr Diab Rep. 2011;11:310-22. This paper reviews the findings on central mechanisms of neuropathic pain in diabetes.
    • (2011) Curr Diab Rep. , vol.11 , pp. 310-322
    • Selvarajah, D.1    Wilkinson, I.D.2    Davies, J.3    Gandhi, R.4    Tesfaye, S.5
  • 131
    • 64149089630 scopus 로고    scopus 로고
    • Thalamic neuron hyperexcitability and enlarged receptive fields in the STZ model of diabetic pain
    • 19285053 1:CAS:528:DC%2BD1MXksVansrw%3D
    • Fischer TZ, Tan AM, Waxman SG. Thalamic neuron hyperexcitability and enlarged receptive fields in the STZ model of diabetic pain. Brain Res. 2009;1268:154-61.
    • (2009) Brain Res , vol.1268 , pp. 154-161
    • Fischer, T.Z.1    Tan, A.M.2    Waxman, S.G.3
  • 132
    • 77956268634 scopus 로고    scopus 로고
    • Neuropathic pain in diabetes-evidence for a central mechanism
    • 20625378 This paper reviews the findings that suggest that thalamic neurons can act as central generators or amplifiers of pain in diabetes
    • • Fischer TZ, Waxman SG. Neuropathic pain in diabetes-evidence for a central mechanism. Nat Rev Neurol. 2010;6:462-6. This paper reviews the findings that suggest that thalamic neurons can act as central generators or amplifiers of pain in diabetes.
    • (2010) Nat Rev Neurol , vol.6 , pp. 462-466
    • Fischer, T.Z.1    Waxman, S.G.2
  • 133
    • 84866179889 scopus 로고    scopus 로고
    • Human Mendelian pain disorders: A key to discovery and validation of novel analgesics
    • 22845492 1:CAS:528:DC%2BC38Xhs1yntbrN
    • Goldberg YP, Pimstone SN, Namdari R, Price N, Cohen C, Sherrington RP, et al. Human Mendelian pain disorders: a key to discovery and validation of novel analgesics. Clin Genet. 2012;82:367-73.
    • (2012) Clin Genet , vol.82 , pp. 367-373
    • Goldberg, Y.P.1    Pimstone, S.N.2    Namdari, R.3    Price, N.4    Cohen, C.5    Sherrington, R.P.6
  • 134
    • 84856143604 scopus 로고    scopus 로고
    • Gain of function Naν1.7 mutations in idiopathic small fiber neuropathy
    • 21698661 1:CAS:528:DC%2BC38XhtFCqtr4%3D
    • Faber CG, Hoeijmakers JG, Ahn HS, Cheng X, Han C, Choi JS, et al. Gain of function Naν1.7 mutations in idiopathic small fiber neuropathy. Ann Neurol. 2012;71:26-39.
    • (2012) Ann Neurol , vol.71 , pp. 26-39
    • Faber, C.G.1    Hoeijmakers, J.G.2    Ahn, H.S.3    Cheng, X.4    Han, C.5    Choi, J.S.6
  • 137
    • 33750683974 scopus 로고    scopus 로고
    • GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence
    • 17057711 1:CAS:528:DC%2BD28XhtFKlsLbK
    • Tegeder I, Costigan M, Griffin RS, Abele A, Belfer I, Schmidt H, et al. GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence. Nat Med. 2006;12:1269-77.
    • (2006) Nat Med , vol.12 , pp. 1269-1277
    • Tegeder, I.1    Costigan, M.2    Griffin, R.S.3    Abele, A.4    Belfer, I.5    Schmidt, H.6
  • 138
    • 77956621874 scopus 로고    scopus 로고
    • Future directions in neuropathic pain therapy: Closing the translational loop
    • Backonja M, Woolf CJ. Future directions in neuropathic pain therapy: closing the translational loop. Oncologist. 2010;2:24-9.
    • (2010) Oncologist , vol.2 , pp. 24-29
    • Backonja, M.1    Woolf, C.J.2
  • 139
    • 9644268053 scopus 로고    scopus 로고
    • Effects of a novel aldose reductase inhibitor, fidarestat (SNK-860), on vibration perception threshold and subjective symptoms in patients with diabetic polyneuropathy: An open-label pilot study
    • Hotta N, Yasuda K, Sumita Y, Sano T, Kakuta H, Nagashima M, et al. Effects of a novel aldose reductase inhibitor, fidarestat (SNK-860), on vibration perception threshold and subjective symptoms in patients with diabetic polyneuropathy: an open-label pilot study. Clin Drug Investig. 2004;24:671-80.
    • (2004) Clin Drug Investig. , vol.24 , pp. 671-680
    • Hotta, N.1    Yasuda, K.2    Sumita, Y.3    Sano, T.4    Kakuta, H.5    Nagashima, M.6
  • 140
    • 11844273799 scopus 로고    scopus 로고
    • Acetyl-L-Carnitine Study Group. Acetyl-L-carnitine improves pain, nerve regeneration, and vibratory perception in patients with chronic diabetic neuropathy: An analysis of 2 randomized placebo-controlled trials
    • 15616239 1:CAS:528:DC%2BD2MXhtFWms7g%3D
    • Sima AA, Calvani M, Mehra M, Amato A. Acetyl-L-Carnitine Study Group. Acetyl-L-carnitine improves pain, nerve regeneration, and vibratory perception in patients with chronic diabetic neuropathy: an analysis of 2 randomized placebo-controlled trials. Diabetes Care. 2005;28:89-94.
    • (2005) Diabetes Care , vol.28 , pp. 89-94
    • Sima, A.A.1    Calvani, M.2    Mehra, M.3    Amato, A.4
  • 141
    • 68149106189 scopus 로고    scopus 로고
    • Treatment of symptomatic polyneuropathy with actovegin in type 2 diabetic patients
    • 19470838 1:CAS:528:DC%2BD1MXhtV2gsL%2FE
    • Ziegler D, Movsesyan L, Mankovsky B, Gurieva I, Abylaiuly Z, Strokov I. Treatment of symptomatic polyneuropathy with actovegin in type 2 diabetic patients. Diabetes Care. 2009;32:1479-84.
    • (2009) Diabetes Care , vol.32 , pp. 1479-1484
    • Ziegler, D.1    Movsesyan, L.2    Mankovsky, B.3    Gurieva, I.4    Abylaiuly, Z.5    Strokov, I.6
  • 142
    • 65649114702 scopus 로고    scopus 로고
    • Vascular endothelial growth factor gene transfer for diabetic polyneuropathy: A randomized, double-blinded trial
    • 19399887
    • Ropper AH, Gorson KC, Gooch CL, Weinberg DH, Pieczek A, Ware JH, et al. Vascular endothelial growth factor gene transfer for diabetic polyneuropathy: a randomized, double-blinded trial. Ann Neurol. 2009;65:386-93.
    • (2009) Ann Neurol , vol.65 , pp. 386-393
    • Ropper, A.H.1    Gorson, K.C.2    Gooch, C.L.3    Weinberg, D.H.4    Pieczek, A.5    Ware, J.H.6
  • 143
    • 1242337352 scopus 로고    scopus 로고
    • Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: A meta-analysis
    • 14984445 1:CAS:528:DC%2BD2cXhvFSgtrs%3D
    • Ziegler D, Nowak H, Kempler P, Vargha P, Low PA. Treatment of symptomatic diabetic polyneuropathy with the antioxidant alpha-lipoic acid: a meta-analysis. Diabet Med. 2004;21:114-21.
    • (2004) Diabet Med , vol.21 , pp. 114-121
    • Ziegler, D.1    Nowak, H.2    Kempler, P.3    Vargha, P.4    Low, P.A.5
  • 144
    • 33845499323 scopus 로고    scopus 로고
    • Oral treatment with alpha-lipoic acid improves symptomatic diabetic polyneuropathy: The SYDNEY 2 trial
    • 17065669 1:CAS:528:DC%2BD28Xht1GktbbP
    • Ziegler D, Ametov A, Barinov A, Dyck PJ, Gurieva I, Low PA, et al. Oral treatment with alpha-lipoic acid improves symptomatic diabetic polyneuropathy: the SYDNEY 2 trial. Diabetes Care. 2006;29:2365-70.
    • (2006) Diabetes Care , vol.29 , pp. 2365-2370
    • Ziegler, D.1    Ametov, A.2    Barinov, A.3    Dyck, P.J.4    Gurieva, I.5    Low, P.A.6
  • 145
    • 84872593274 scopus 로고    scopus 로고
    • Metanx in type 2 diabetes with peripheral neuropathy: A randomized trial
    • 23218892 1:CAS:528:DC%2BC38Xhsl2jtbfP
    • Fonseca VA, Lavery LA, Thethi TK, Daoud Y, DeSouza C, Ovalle F, et al. Metanx in type 2 diabetes with peripheral neuropathy: a randomized trial. Am J Med. 2013;126:141-9.
    • (2013) Am J Med , vol.126 , pp. 141-149
    • Fonseca, V.A.1    Lavery, L.A.2    Thethi, T.K.3    Daoud, Y.4    Desouza, C.5    Ovalle, F.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.