Systemic inflammation with enhanced brain activation contributes to more severe delay in postoperative ileus

Neurogastroenterology and Motility

Volumn 25, Issue 8, 2013, Pages

  van Bree, S H W ^a   Cailotto, C ^a   Di Giovangiulio, M ^b   Jansen, E ^a   van der Vliet, J ^a   Costes, L ^a   Depoortere, I ^b   Gomez Pinilla, P J ^b   Matteoli, G ^b   Boeckxstaens, G E E ^a,b  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Gastrointestinal motility; Inflammation; Postoperative ileus; Tissue damage

Indexed keywords

BIOLOGICAL MARKER; I FABP PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA POSTREMA; ARTICLE; BRAIN FUNCTION; CONCENTRATION (PARAMETERS); CYTOKINE PRODUCTION; GASTROINTESTINAL TRANSIT; GENE EXPRESSION; HUMAN; IMMUNOHISTOCHEMISTRY; INTESTINE MUSCLE; LEUKOCYTE; LYMPHOCYTIC INFILTRATION; MOUSE; NONHUMAN; ONCOGENE C FOS; POSTOPERATIVE ILEUS; PRIORITY JOURNAL; RNA EXTRACTION; TISSUE INJURY;

GASTROINTESTINAL MOTILITY; INFLAMMATION; POSTOPERATIVE ILEUS; TISSUE DAMAGE;

ANIMALS; BRAIN; GASTROINTESTINAL TRANSIT; HUMANS; ILEUS; INFLAMMATION MEDIATORS; MICE, INBRED C57BL; POSTOPERATIVE COMPLICATIONS; SEVERITY OF ILLNESS INDEX; TIME FACTORS;

EID: 84880133178     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/nmo.12157     Document Type: Article

References (36)

1. van Bree SH, Nemethova A, Cailotto C et al. New therapeutic strategies for postoperative ileus. Nat Rev Gastroenterol Hepatol 2012; 9: 675-83.
2. Kalff JC, Carlos TM, Schraut WH et al. Surgically induced leukocytic infiltrates within the rat intestinal muscularis mediate postoperative ileus. Gastroenterology 1999; 117: 378-87.
3. The FO, Bennink RJ, Ankum WM et al. Intestinal handling-induced mast cell activation and inflammation in human postoperative ileus. Gut 2008; 57: 33-40.
4. van Bree S, Vlug M, Bemelman W et al. Faster recovery of gastrointestinal transit after laparoscopy and fast-track care in patients undergoing colonic surgery. Gastroenterology 2011; 141: 872-80, e871-874.
5. Kalff JC, Schraut WH, Simmons RL, Bauer AJ. Surgical manipulation of the gut elicits an intestinal muscularis inflammatory response resulting in postsurgical ileus. Ann Surg 1998; 228: 652-63.
6. Kalff JC, Schraut WH, Billiar TR et al. Role of inducible nitric oxide synthase in postoperative intestinal smooth muscle dysfunction in rodents. Gastroenterology 2000; 118: 316-27.
7. van Bree SHW, Nemethova A, van de Bovenkamp FS et al. Novel method for studying postoperative ileus in mice. Int J Physiol Pathophysiol Pharmacol 2012; 4: 219-27.
8. Veenhof AA, Sietses C, von Blomberg BM et al. The surgical stress response and postoperative immune function after laparoscopic or conventional total mesorectal excision in rectal cancer: a randomized trial. Int J Colorectal Dis 2011; 26: 53-9.
9. Novitsky YW, Litwin DE, Callery MP. The net immunologic advantage of laparoscopic surgery. Surg Endosc 2004; 18: 1411-9.
10. Rock KL, Latz E, Ontiveros F, Kono H. The sterile inflammatory response. Annu Rev Immunol 2010; 28: 321-42.
11. The F, Cailotto C, van der Vliet J et al. Central activation of the cholinergic anti-inflammatory pathway reduces surgical inflammation in experimental post-operative ileus. Br J Pharmacol 2011; 163: 1007-16.
12. Kalff JC, Schwarz NT, Walgenbach KJ et al. Leukocytes of the intestinal muscularis: their phenotype and isolation. J Leukoc Biol 1998; 63: 683-91.
13. Schmidt J, Stoffels B, Moore BA et al. Proinflammatory role of leukocyte-derived Egr-1 in the development of murine postoperative ileus. Gastroenterology 2008; 135: 926-36. 936 e921-922.
14. Engel DR, Koscielny A, Wehner S et al. T helper type 1 memory cells disseminate postoperative ileus over the entire intestinal tract. Nat Med 2010; 16: 1407-13.
15. Pelsers MM, Hermens WT, Glatz JF. Fatty acid-binding proteins as plasma markers of tissue injury. Clin Chim Acta 2005; 352: 15-35.
16. Barquist E, Bonaz B, Martinez V et al. Neuronal pathways involved in abdominal surgery-induced gastric ileus in rats. Am J Physiol 1996; 270: R888-94.
17. Koga T, Fukuda H. Neurons in the nucleus of the solitary tract mediating inputs from emetic vagal afferents and the area postrema to the pattern generator for the emetic act in dogs. Neurosci Res 1992; 14: 166-79.
18. Karcsu S, Jancso G, Kreutzberg GW et al. A glutamate-sensitive neuronal system originating from the area postrema terminates in and transports acetylcholinesterase to the nucleus of the solitary tract. J Neurocytol 1985; 14: 563-78.
19. Buchholz BM, Chanthaphavong RS, Bauer AJ. Nonhemopoietic cell TLR4 signaling is critical in causing early lipopolysaccharide-induced ileus. J Immunol 2009; 183: 6744-53.
20. Wehner S, Straesser S, Vilz TO et al. Inhibition of p38 mitogen-activated protein kinase pathway as prophylaxis of postoperative ileus in mice. Gastroenterology 2009; 136: 619-29.
21. Graber JN, Schulte WJ, Condon RE, Cowles VE. Relationship of duration of postoperative ileus to extent and site of operative dissection. Surgery 1982; 92: 87-92.
22. Uemura K, Tatewaki M, Harris MB et al. Magnitude of abdominal incision affects the duration of postoperative ileus in rats. Surg Endosc 2004; 18: 606-10.
23. Vlug MS, Diepenhorst GM, van Koperen PJ et al. Intestinal barrier function in patients undergoing colectomy. Colorectal Dis 2011; 13: 1432-7.
24. de Haan JJ, Lubbers T, Hadfoune M et al. Postshock intervention with high-lipid enteral nutrition reduces inflammation and tissue damage. Ann Surg 2008; 248: 842-8.
25. Pelsers MMAL, Namiot Z, Kisielewski W et al. Intestinal-type and liver-type fatty acid-binding protein in the intestine. Tissue distribution and clinical utility. Clin Biochem 2003; 36: 529-35.
26. Gakis G, Mueller MH, Hahn J et al. Neuronal activation in the nucleus of the solitary tract following jejunal lipopolysaccharide in the rat. Auton Neurosci 2009; 148: 63-8.
27. Bonaz B, Plourde V, Tache Y. Abdominal surgery induces Fos immunoreactivity in the rat brain. J Comp Neurol 1994; 349: 212-22.
28. Bonaz B, Tache Y. Corticotropin-releasing factor and systemic capsaicin-sensitive afferents are involved in abdominal surgery-induced Fos expression in the paraventricular nucleus of the hypothalamus. Brain Res 1997; 748: 12-20.
29. Buller KM. Role of circumventricular organs in pro-inflammatory cytokine-induced activation of the hypothalamic-pituitary-adrenal axis. Clin Exp Pharmacol Physiol 2001; 28: 581-9.
30. Kreiss C, Toegel S, Bauer AJ. Alpha2-adrenergic regulation of NO production alters postoperative intestinal smooth muscle dysfunction in rodents. Am J Physiol Gastrointest Liver Physiol 2004; 287: G658-66.
31. Schwarz NT, Kalff JC, Turler A et al. Prostanoid production via COX-2 as a causative mechanism of rodent postoperative ileus. Gastroenterology 2001; 121: 1354-71.
32. de Jonge WJ, van Den Wijngaard RM, The FO et al. Postoperative ileus is maintained by intestinal immune infiltrates that activate inhibitory neural pathways in mice. Gastroenterology 2003; 125: 1137-47.
33. Schwarz NT, Kalff JC, Turler A et al. Selective jejunal manipulation causes postoperative pan-enteric inflammation and dysmotility. Gastroenterology 2004; 126: 159-69.
34. Snoek SA, Dhawan S, van Bree SH et al. Mast cells trigger epithelial barrier dysfunction, bacterial translocation and postoperative ileus in a mouse model. Neurogastroenterol Motil 2012; 24: 172-84.
35. Matteoli G, Gomez-Pinilla PJ, Nemethova A et al. Intestinal resident macrophages expressing a7nAChR mediate the anti-inflammatory effect of vagus nerve stimulation in postoperative ileus. Gastroenterology 2012; 142 (5 Suppl. 1): S-125; Digestive Disease Week 2012.
36. Kreiss C, Birder LA, Kiss S et al. COX-2 dependent inflammation increases spinal Fos expression during rodent postoperative ileus. Gut 2003; 52: 527-34.