1,25-dihydroxyvitamin D3 activates MMP13 gene expression in chondrocytes through p38 MARK pathway

International Journal of Biological Sciences

Volumn 9, Issue 6, 2013, Pages 649-655

  Chen, Dafu ^a   Li, Yang ^b   Dai, Xuejun ^c   Zhou, Xinhua ^a   Tian, Wei ^a   Zhou, Yixin ^a   Zou, Xuenong ^c   Zhang, Chi ^b  

^a Beijing Jishuitan Hospital   (China)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

Author keywords

1,25 (OH)2D3; Chondrocyte; Gene expression; MMP13; Osteoarthritis; P38

Indexed keywords

AGGRECAN; CALCITRIOL; COLLAGEN TYPE 2; COLLAGENASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PRIMER DNA;

1,25-(OH)2D3; ARTICLE; CARTILAGE CELL; CELL CULTURE; CHONDROCYTE.; DOSE RESPONSE; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; NUCLEOTIDE SEQUENCE; OSTEOARTHRITIS; P38; PHOSPHORYLATION; PROMOTER REGION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

1,25-(OH)2D3; CHONDROCYTE.; GENE EXPRESSION; MMP13; OSTEOARTHRITIS; P38;

AGGRECANS; BASE SEQUENCE; CALCITRIOL; CELLS, CULTURED; CHONDROCYTES; COLLAGEN TYPE II; DNA PRIMERS; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; MATRIX METALLOPROTEINASE 13; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84880112504     PISSN: 14492288     EISSN: None     Source Type: Journal    
DOI: 10.7150/ijbs.6726     Document Type: Article

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