Maternal exposure to combustion generated PM inhibits pulmonary Th1 maturation and concomitantly enhances postnatal asthma development in offspring

Particle and Fibre Toxicology

Volumn 10, Issue 1, 2013, Pages

  Wang, Pingli ^a,b   You, Dahui ^a   Saravia, Jordy ^a   Shen, Huahao ^b,c   Cormier, Stephania A ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c State Key Laboratory of Respiratory Diseases   (China)

Author keywords

Asthma; Maternal exposure; Offspring; Particulate matter

Indexed keywords

8 ISOPROSTANE; GAMMA INTERFERON; INTERLEUKIN 17 ANTIBODY; INTERLEUKIN 4; INTERLEUKIN 5; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; RANTES; TRANSCRIPTION FACTOR FOXP3; 8-EPI-PROSTAGLANDIN F2ALPHA; AUTACOID; CYTOKINE; OVALBUMIN; PARTICULATE MATTER; PROSTAGLANDIN F2 ALPHA;

ANIMAL CELL; ARTICLE; ASTHMA; BLOOD SAMPLING; CD4+ CD25+ T LYMPHOCYTE; CELL MATURATION; COMBUSTION; CONTROLLED STUDY; CYTOKINE RESPONSE; DISEASE SEVERITY; EOSINOPHILIA; FEMALE; GESTATION PERIOD; LUNG LAVAGE; LYMPHOCYTE SUBPOPULATION; MOUSE; MUCUS SECRETION; NONHUMAN; OXIDATIVE STRESS; PARTICULATE MATTER; PERINATAL PERIOD; POSTNATAL DEVELOPMENT; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROGENY; REGULATORY T LYMPHOCYTE; RESPIRATORY TRACT ALLERGY; RESPIRATORY TRACT INFECTION; T LYMPHOCYTE; TH1 CELL; TH17 CELL; TH2 CELL; ADVERSE EFFECTS; AGE; ANALOGS AND DERIVATIVES; ANIMAL; BLOOD; BRONCHIAL HYPERREACTIVITY; C57BL MOUSE; CHEMICALLY INDUCED; DRUG EFFECTS; EMBRYOLOGY; ENVIRONMENTAL EXPOSURE; EXPOSURE; GESTATIONAL AGE; IMMUNOLOGY; LOEFFLER PNEUMONIA; LUNG; METABOLISM; PREGNANCY; SEVERITY OF ILLNESS INDEX; TOXICITY;

MUS;

AGE FACTORS; ANIMALS; ASTHMA; BRONCHIAL HYPERREACTIVITY; CYTOKINES; DINOPROST; FEMALE; GESTATIONAL AGE; INFLAMMATION MEDIATORS; INHALATION EXPOSURE; LUNG; MATERNAL EXPOSURE; MICE, INBRED C57BL; OVALBUMIN; OXIDATIVE STRESS; PARTICULATE MATTER; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PULMONARY EOSINOPHILIA; SEVERITY OF ILLNESS INDEX; T-LYMPHOCYTES, REGULATORY; TH1 CELLS; TH17 CELLS; TH2 CELLS;

EID: 84880094305     PISSN: None     EISSN: 17438977     Source Type: Journal    
DOI: 10.1186/1743-8977-10-29     Document Type: Article

References (30)

1. Akinbami LJMJ, Liu X. Asthma prevalence, health care use, and mortality: United States, 2005-2009. Natl Health Stat Report 2011, 32:1-14.
2. Calvani M, Alessandri C, Sopo SM, Panetta V, Tripodi S, Torre A, Pingitore G, Frediani T, Volterrani A, Lazio Association of Pediatric Allergology Study G Infectious and uterus related complications during pregnancy and development of atopic and nonatopic asthma in children. Allergy 2004, 59:99-106. 10.1046/j.1398-9995.2003.00338.x, 14674941, Lazio Association of Pediatric Allergology Study G.
3. Carlsten C, Dybuncio A, Becker A, Chan-Yeung M, Brauer M. Traffic-related air pollution and incident asthma in a high-risk birth cohort. Occup Environ Med 2011, 68:291-295. 10.1136/oem.2010.055152, 20952556.
4. Hunt A, Crawford JA, Rosenbaum PF, Abraham JL. Levels of household particulate matter and environmental tobacco smoke exposure in the first year of life for a cohort at risk for asthma in urban Syracuse, NY. Environ Int 2011, 37:1196-1205. 10.1016/j.envint.2011.04.013, 21620473.
5. Kelly FJ, Fussell JC. Air pollution and airway disease. Clin Exp Allergy 2011, 41:1059-1071. 10.1111/j.1365-2222.2011.03776.x, 21623970.
6. Nafstad P, Magnus P, Jaakkola JJ. Risk of childhood asthma and allergic rhinitis in relation to pregnancy complications. J Allergy Clin Immunol 2000, 106:867-873. 10.1067/mai.2000.110558, 11080708.
7. Reponen T, Vesper S, Levin L, Johansson E, Ryan P, Burkle J, Grinshpun SA, Zheng S, Bernstein DI, Lockey J, et al. High environmental relative moldiness index during infancy as a predictor of asthma at 7 years of age. Ann Allerg Asthma Im 2011, 107:120-126.
8. Skorge TD, Eagan TM, Eide GE, Gulsvik A, Bakke PS. The adult incidence of asthma and respiratory symptoms by passive smoking in uterus or in childhood. Am J Respir Crit Care Med 2005, 172:61-66. 10.1164/rccm.200409-1158OC, 15805186.
9. Holladay SD, Smialowicz RJ. Development of the murine and human immune system: differential effects of immunotoxicants depend on time of exposure. Environ Health Perspect 2000, 108(Suppl 3):463-473. 1637831, 10852846.
10. Lomnicki S, Dellinger B. A Detailed Mechanism of The Surface-Mediated Formation of PCDD/F from the Oxidation of 2-Chlorophenol on CuO/ Silica Surface. J Phys Chem A 2003, 107:4387-4395.
11. Lomnicki S, Truong H, Vejerano E, Dellinger B. Copper oxide-based model of persistent free radical formation on combustion-derived particulate matter. Environ Sci Technol 2008, 42:4982-4988. 10.1021/es071708h, 18678037.
12. Nganai S, Lomnicki S, Dellinger B. Ferric oxide mediated formation of PCDD/Fs from 2-monochlorophenol. Environ Sci Technol 2009, 43:368-373. 10.1021/es8022495, 3573702, 19238966.
13. Balakrishna S, Lomnicki S, McAvey KM, Cole RB, Dellinger B, Cormier SA. Environmentally persistent free radicals amplify ultrafine particle mediated cellular oxidative stress and cytotoxicity. Part Fibre Toxicol 2009, 6:11. 10.1186/1743-8977-6-11, 2676242, 19374750.
14. Wang P, Thevenot P, Saravia J, Ahlert T, Cormier SA. Radical-containing particles activate dendritic cells and enhance Th17 inflammation in a mouse model of asthma. Am J Respir Cell Mol Biol 2011, 45:977-983. 10.1165/rcmb.2011-0001OC, 3262685, 21493781.
15. Kinnula VL, Ilumets H, Myllarniemi M, Sovijarvi A, Rytila P. 8-Isoprostane as a marker of oxidative stress in nonsymptomatic cigarette smokers and COPD. Eur Respir J 2007, 29:51-55.
16. Hartel C, Adam N, Strunk T, Temming P, Muller-Steinhardt M, Schultz C. Cytokine responses correlate differentially with age in infancy and early childhood. Clin Exp Immunol 2005, 142:446-453. 1809539, 16297156.
17. Wang L, Joad JP, Abel K, Spinner A, Smiley-Jewell S, Liu H, Pinkerton KE. Effects of environmental tobacco smoke on the developing immune system of infant monkeys. J Allergy Clin Immun 2007, 120:445-451. 10.1016/j.jaci.2007.03.028, 17482667.
18. Shirakawa T, Enomoto T, Shimazu S, Hopkin JM. The inverse association between tuberculin responses and atopic disorder. Science 1997, 275:77-79. 10.1126/science.275.5296.77, 8974396.
19. Baccarelli A, Bollati V. Epigenetics and environmental chemicals. Curr Opin Pediatr 2009, 21:243-251. 10.1097/MOP.0b013e32832925cc, 3035853, 19663042.
20. Kim KY, Kim DS, Lee SK, Lee IK, Kang JH, Chang YS, Jacobs DR, Steffes M, Lee DH. Association of Low-Dose Exposure to Persistent Organic Pollutants with Global DNA Hypomethylation in Healthy Koreans. Environ Health Persp 2010, 118:370-374.
21. Orphanides G, Reinberg D. A unified theory of gene expression. Cell 2002, 108:439-451. 10.1016/S0092-8674(02)00655-4, 11909516.
22. Liu J, Ballaney M, Al-Alem U, Quan C, Jin X, Perera F, Chen LC, Miller RL. Combined inhaled diesel exhaust particles and allergen exposure alter methylation of T helper genes and IgE production In vivo. Toxicol Sci 2008, 102:76-81. 2268643, 18042818.
23. Martino DJ, Prescott SL. Silent mysteries: epigenetic paradigms could hold the key to conquering the epidemic of allergy and immune disease. Allergy 2010, 65:7-15. 10.1111/j.1398-9995.2009.02186.x, 19796189.
24. White GP, Watt PM, Holt BJ, Holt PG. Differential patterns of methylation of the IFN-gamma promoter at CpG and Non-CpG sites underlie differences in IFN-gamma gene expression between human neonatal and adult CD45RO(-) T cells. J Immunol 2002, 168:2820-2827.
25. Valinluck V, Tsai HH, Rogstad DK, Burdzy A, Bird A, Sowers LC. Oxidative damage to methyl-CpG sequences inhibits the binding of the methyl-CpG binding domain (MBD) of methyl-CpG binding protein 2 (MeCP2). Nucleic Acids Res 2004, 32:4100-4108. 10.1093/nar/gkh739, 514367, 15302911.
26. Frossi B, De Carli M, Piemonte M, Pucillo C. Oxidative microenvironment exerts an opposite regulatory effect on cytokine production by Th1 and Th2 cells. Mol Immunol 2008, 45:58-64. 10.1016/j.molimm.2007.05.008, 17588662.
27. King MR, Ismail AS, Davis LS, Karp DR. Oxidative stress promotes polarization of human T cell differentiation toward a T helper 2 phenotype. J Immunol 2006, 176:2765-2772.
28. Council NR. Guide for the Care and Use of Laboratory Animals 1996, Washington, DC: National Academic Press.
29. Ormerod MG. Preparing suspensions of single cells 2000, Oxford: Oxford University Press.
30. You D, Becnel D, Wang K, Ripple M, Daly M, Cormier SA. Exposure of neonates to Respiratory Syncytial Virus is critical in determining subsequent airway response in adults. Resp Res 2006, 7:107.