Urinary proteome in a snapshot: Normal urine and glomerulonephritis

Journal of Nephrology

Volumn 26, Issue 4, 2013, Pages 610-616

  Santucci, Laura ^a   Candiano, Giovanni ^a   Bruschi, Maurizio ^a   Bodria, Monica ^b   Murtas, Corrado ^a   Petretto, Andrea ^a   Ghiggeri, Gian Marco ^a  

^a G GASLINI INSTITUTE   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

Glomerulonephritis; Normal urine; Urinary proteome

Indexed keywords

ALBUMIN; ALPHA 1 ANTITRYPSIN; BETA 2 MICROGLOBULIN; BIOLOGICAL MARKER; CERULOPLASMIN; GLYCOPROTEIN; HAPTOGLOBIN; HEPCIDIN; IMMUNOGLOBULIN G; MEMBRANE PROTEIN; MICROSOMAL AMINOPEPTIDASE; PROSTAGLANDIN SYNTHASE; PROTEOME; UNCLASSIFIED DRUG; VASORIN PRECURSOR;

ANALYTIC METHOD; ARTICLE; CELL VACUOLE; EXOSOME; GLOMERULONEPHRITIS; HUMAN; IMMUNOGLOBULIN A NEPHROPATHY; LUPUS ERYTHEMATOSUS NEPHRITIS; NEPHROTIC SYNDROME; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN URINE LEVEL; URINALYSIS; URINE;

GLOMERULONEPHRITIS; HUMANS; NEPHROTIC SYNDROME; PROTEINURIA; PROTEOME;

EID: 84880082960     PISSN: 11218428     EISSN: 17246059     Source Type: Journal    
DOI: 10.5301/jn.5000233     Document Type: Article

References (54)

1. Rennke HG, Patel Y, Venkatachalam MA. Glomerular filtration of proteins: clearance of anionic, neutral, and cationic horseradish peroxidase in the rat. Kidney Int. 1978;13(4):278-288.
2. Brenner BM, Hostetter TH, Humes HD. Glomerular permselectivity: barrier function based on discrimination of molecular size and charge. Am J Physiol. 1978;234(6):F455-F460.
3. Ghiggeri GM, Candiano G, Ginevri F, et al. Renal selectivity properties towards endogenous albumin in minimal change nephropathy. Kidney Int. 1987;32(1):69-77.
4. Ghiggeri GM, Ginevri F, Candiano G, et al. Characterization of cationic albumin in minimal change nephropathy. Kidney Int. 1987;32(4):547-553.
5. Brenner BM, Hostetter TH, Humes HD. Molecular basis of proteinuria of glomerular origin. N Engl J Med. 1978; 298(15):826-833.
6. Mischak H, Apweiler R, Banks RE, et al. Clinical proteomics: a need to define the field and to begin to set adequate standards. Proteomics Clin Appl. 2007;1(2):148-156.
7. González-Buitrago JM, Ferreira L, Lorenzo I. Urinary proteomics. Clin Chim Acta. 2007;375(1-2):49-56.
8. Hewitt SM, Dear J, Star RA. Discovery of protein biomarkers for renal diseases. J Am Soc Nephrol. 2004;15(7):1677-1689.
9. O'Riordan E, Orlova TN, Mei JJ, et al. Bioinformatic analysis of the urine proteome of acute allograft rejection. J Am Soc Nephrol. 2004;15(12):3240-3248.
10. Schaub S, Wilkins J, Weiler T, Sangster K, Rush D, Nickerson P. Urine protein profiling with surface-enhanced laser-desorption/ionization time-of-flight mass spectrometry. Kidney Int. 2004;65(1):323-332.
11. Theodorescu D, Wittke S, Ross MM, et al. Discovery and validation of new protein biomarkers for urothelial cancer: a prospective analysis. Lancet Oncol. 2006;7(3):230-240.
12. Lee RS, Monigatti F, Briscoe AC, Waldon Z, Freeman MR, Steen H. Optimizing sample handling for urinary proteomics. J Proteome Res. 2008;7(9):4022-4030.
13. Tencer J, Thysell H, Andersson K, Grubb A. Stability of albumin, protein HC, immunoglobulin G, kappaand lambdachain immunoreactivity, orosomucoid and alpha 1-antitrypsin in urine stored at various conditions. Scand J Clin Lab Invest. 1994;54(3):199-206.
14. Bruschi M, Musante L, Candiano G, et al. Soft immobilized pH gradient gels in proteome analysis: a follow-up. Proteomics. 2003;3(6):821-825.
15. Joo WA, Lee DY, Kim CW. Development of an effective sample preparation method for the proteome analysis of body fluids using 2-D gel electrophoresis. Biosci Biotechnol Biochem. 2003;67(7):1574-1577.
16. Candiano G, Musante L, Bruschi M, et al. Two-dimensional maps in soft immobilized pH gradient gels: a new approach to the proteome of the Third Millennium. Electrophoresis. 2002;23(2):292-297.
17. Switzer RC III, Merril CR, Shifrin S. A highly sensitive silver stain for detecting proteins and peptides in polyacrylamide gels. Anal Biochem. 1979;98(1):231-237.
18. Adams LD, Sammons DW. A unique silver staining procedure for color characterization of polypeptides. In: Allen RC, Arnaud P, eds. Electrophoresis. Berlin, New York: Walter de Gruyter; 1981:155-165.
19. Candiano G, Bruschi M, Musante L, et al. Blue silver: a very sensitive colloidal Coomassie G-250 staining for proteome analysis. Electrophoresis. 2004;25(9):1327-1333.
20. Oakley BR, Kirsch DR, Morris NR. A simplified ultrasensitive silver stain for detecting proteins in polyacrylamide gels. Anal Biochem. 1980;105(2):361-363.
21. Marouga R, David S, Hawkins E. The development of the DIGE system: 2D fluorescence difference gel analysis technology. Anal Bioanal Chem. 2005;382(3):669-678.
22. Sharma K, Lee S, Han S, et al. Two-dimensional fluorescence difference gel electrophoresis analysis of the urine proteome in human diabetic nephropathy. Proteomics. 2005;5(10): 2648-2655.
23. Tonge R, Shaw J, Middleton B, et al. Validation and development of fluorescence two-dimensional differential gel electrophoresis proteomics technology. Proteomics. 2001;1(3):377-396.
24. Van den Bergh G, Arckens L. Fluorescent two-dimensional difference gel electrophoresis unveils the potential of gelbased proteomics. Curr Opin Biotechnol. 2004;15(1):38-43.
25. Unlü M, Morgan ME, Minden JS. Difference gel electrophoresis: a single gel method for detecting changes in protein extracts. Electrophoresis. 1997;18(11):2071-2077.
26. Shaw J, Rowlinson R, Nickson J, et al. Evaluation of saturation labelling two-dimensional difference gel electrophoresis fluorescent dyes. Proteomics. 2003;3(7):1181-1195.
27. Bruschi M, Grilli S, Candiano G, et al. New iodo-acetamido cyanines for labeling cysteine thiol residues. A strategy for evaluating plasma proteins and their oxido-redox status. Proteomics. 2009;9(2):460-469.
28. Knowles MR, Cervino S, Skynner HA, et al. Multiplex proteomic analysis by two-dimensional differential in-gel electrophoresis. Proteomics. 2003;3(7):1162-1171.
29. Candiano G, Santucci L, Petretto A, et al. 2D-Electrophoresis and the urine proteome map: where do we stand? J Proteomics. 2010;73(5):829-844.
30. Boschetti E, Righetti PG. The ProteoMiner in the proteomic arena: a non-depleting tool for discovering low-abundance species. J Proteomics. 2008;71(3):255-264.
31. Boschetti E, Righetti PG. The art of observing rare protein species in proteomes with peptide ligand libraries. Proteomics. 2009;9(6):1492-1510.
32. Candiano G, Santucci L, Bruschi M, et al. "Cheek-to-cheek" urinary proteome profiling via combinatorial peptide ligand libraries: a novel, unexpected elution system. J Proteomics. 2012;75(3):796-805.
33. Righetti PG, Boschetti E. The ProteoMiner and the Forty Niners: searching for gold nuggets in the proteomic arena. Mass Spectrom Rev. 2008;27(6):596-608.
34. Righetti PG, Boschetti E, Zanella A, Fasoli E, Citterio A. Plucking, pillaging and plundering proteomes with combinatorial peptide ligand libraries. J Chromatogr A. 2010;1217(6): 893-900.
35. Musante L, Candiano G, Petretto A, et al. Active focal segmental glomerulosclerosis is associated with massive oxidation of plasma albumin. J Am Soc Nephrol. 2007;18(3):799-810.
36. Raj DA, Fiume I, Capasso G, Pocsfalvi G. A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes. Kidney Int. 2012;81(12):1263-1272.
37. Hortin GL. A new era in protein quantification in clinical laboratories: application of liquid chromatography-tandem mass spectrometry. Clin Chem. 2007;53(4):543-544.
38. Branten AJ, du Buf-Vereijken PW, Klasen IS, et al. Urinary excretion of beta2-microglobulin and IgG predict prognosis in idiopathic membranous nephropathy: a validation study. J Am Soc Nephrol. 2005;16(1):169-174.
39. Ngai HH, Sit WH, Jiang PP, Thongboonkerd V, Wan JM. Markedly increased urinary preprohaptoglobin and haptoglobin in passive Heymann nephritis: a differential proteomics approach. J Proteome Res. 2007;6(8):3313-3320.
40. Shui HA, Huang TH, Ka SM, Chen PH, Lin YF, Chen A. Urinary proteome and potential biomarkers associated with serial pathogenesis steps of focal segmental glomerulosclerosis. Nephrol Dial Transplant. 2008;23(1):176-185.
41. Varghese SA, Powell TB, Budisavljevic MN, et al. Urine biomarkers predict the cause of glomerular disease. J Am Soc Nephrol. 2007;18(3):913-922.
42. Candiano G, Musante L, Bruschi M, et al. Repetitive fragmentation products of albumin and alpha1-antitrypsin in glomerular diseases associated with nephrotic syndrome. J Am Soc Nephrol. 2006;17(11):3139-3148.
43. Candiano G, Bruschi M, Petretto A, et al. Proteins and protein fragments in nephrotic syndrome: clusters, specificity and mechanisms. Proteomics Clin Appl. 2008;2(7-8):956-963.
44. Antonioli P, Mendieta ME, Sebastiano R, et al. Quasiisoelectric buffers for protein analysis in a fast alternative to conventional capillary zone electrophoresis. J Chromatogr B Analyt Technol Biomed Life Sci. 2006;833(1):19-25.
45. Ottonello L, Dapino P, Scirocco M, Dallegri F, Sacchetti C. Proteolytic inactivation of alpha-1-antitrypsin by human neutrophils: involvement of multiple and interlinked cell responses to phagocytosable targets. Eur J Clin Invest. 1994;24(1):42-49.
46. Park MR, Wang EH, Jin DC, et al. Establishment of a 2-D human urinary proteomic map in IgA nephropathy. Proteomics. 2006;6(3):1066-1076.
47. He Q, Shao L, Yu J, et al. Urinary proteome analysis by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry with magnetic beads for identifying the pathologic presentation of clinical early IgA nephropathy. J Biomed Nanotechnol. 2012;8(1):133-139.
48. Rocchetti MT, Tamma G, Lasorsa D, et al. Altered urinary excretion of aquaporin 2 in IgA nephropathy. Eur J Endocrinol. 2011;165(4):657-664.
49. Moon PG, Lee JE, You S, et al. Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. Proteomics. 2011;11(12): 2459-2475.
50. Oates JC, Varghese S, Bland AM, et al. Prediction of urinary protein markers in lupus nephritis. Kidney Int. 2005;68(6): 2588-2592.
51. Somparn P, Hirankarn N, Leelahavanichkul A, Khovidhunkit W, Thongboonkerd V, Avihingsanon Y. Urinary proteomics revealed prostaglandin H(2)D-isomerase, not Znα2-glycoprotein, as a biomarker for active lupus nephritis. J Proteomics. 2012;75(11):3240-3247.
52. Buckmaster R, Asphahani F, Thein M, Xu J, Zhang M. Detection of drug-induced cellular changes using confocal Raman spectroscopy on patterned single-cell biosensors. Analyst. 2009;134(7):1440-1446.
53. Yamamoto T, Langham RG, Ronco P, Knepper MA, Thongboonkerd V. Towards standard protocols and guidelines for urine proteomics: a report on the Human Kidney and Urine Proteome Project (HKUPP) symposium and workshop, 6 October 2007, Seoul, Korea and 1 November 2007, San Francisco, CA, USA. Proteomics. 2008;8(11):2156-2159.
54. Vlahou A, Schanstra J, Frokiaer J, et al. European Kidney and Urine Proteomics Network. Establishment of a European Network for Urine and Kidney Proteomics. J Proteomics. 2008;71(4):490-492.