Nuclear BAG6-UBL4A-GET4 complex mediates DNA damage signaling and cell death

Journal of Biological Chemistry

Volumn 288, Issue 28, 2013, Pages 20547-20557

  Krenciute, Giedre ^a   Liu, Shangfeng ^a,c   Yucer, Nur ^a   Shi, Yi ^a,d   Ortiz, Priscilla ^a   Liu, Qiongming ^b   Kim, Beom Jun ^a   Odejimi, Abiola Ore ^a   Leng, Mei ^a   Qin, Jun ^a   Wang, Yi ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^c TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

^d ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CENTRAL COMPONENT; DNA DAMAGE RESPONSE; DNA DAMAGING AGENTS; MEMBRANE PROTEINS; NUCLEAR LOCALIZATION; NUCLEAR LOCALIZATION SIGNAL; PROTEIN QUALITY CONTROL; STABLE COMPLEXES;

BIOLOGICAL MEMBRANES; CELL DEATH; PHOSPHORYLATION; PROTEINS;

DNA;

ATM PROTEIN; ATR PROTEIN; BAG 6 PROTEIN; BRCA1 PROTEIN; DNA; GET4 PROTEIN; NUCLEAR PROTEIN; UBL4A PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL DEATH; CELL NUCLEUS; CELLULAR DISTRIBUTION; CELLULAR STRESS RESPONSE; COMPLEX FORMATION; CONTROLLED STUDY; CYTOPLASM; DNA DAMAGE; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION;

ATM; BAG6; CELL CYCLE; CELL DEATH; CHECKPOINT CONTROL; DNA DAMAGE RESPONSE; GET4; PROTEIN TRANSLOCATION; UBL4A;

BLOTTING, WESTERN; CELL CYCLE PROTEINS; CELL DEATH; CELL LINE; CELL LINE, TUMOR; CELL NUCLEUS; CELL SURVIVAL; DNA DAMAGE; DNA-BINDING PROTEINS; HELA CELLS; HUMANS; MCF-7 CELLS; MICROSCOPY, FLUORESCENCE; MOLECULAR CHAPERONES; MULTIPROTEIN COMPLEXES; MUTATION; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS; UBIQUITINS;

EID: 84880059173     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.443416     Document Type: Article

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