Power spectral analysis of heart rate variability in cynomolgus monkeys in safety pharmacology studies: Comparative study with beagle dogs

Journal of Pharmacological and Toxicological Methods

Volumn 68, Issue 1, 2013, Pages 166-174

  Champeroux, Pascal ^a   Martel, Eric ^a   Jude, Sebastien ^a   Laigot, Christine ^a   Laveissière, Arnaud ^a   Weyn Marotte, Andrée Anne ^a   Fowler, John Sinclair Lawrence ^a   Maurin, Anne ^a   Richard, Serge ^a   Babuty, Dominique ^b  

^a CERB   (France)

^b SERVICE DE DERMATOLOGIE   (France)

Author keywords

Beagle dogs; Cynomolgus monkeys; Heart rate variability; Power spectral analysis; Safety pharmacology; Telemetry

Indexed keywords

ADRENERGIC RECEPTOR BLOCKING AGENT; ADRENERGIC RECEPTOR STIMULATING AGENT; ATENOLOL; ATROPINE; CHOLINERGIC RECEPTOR BLOCKING AGENT; CHOLINERGIC RECEPTOR STIMULATING AGENT; CLONIDINE; NICARDIPINE;

ANIMAL EXPERIMENT; ARTICLE; AUTONOMIC NERVOUS SYSTEM; CHOLINERGIC SYSTEM; COMPARATIVE STUDY; CONTROLLED STUDY; DOG; DRUG EFFECT; DRUG RESPONSE; DRUG SAFETY; ELECTROCARDIOGRAM; FEMALE; HAPLORHINI; HEART RATE; HEART RATE VARIABILITY; MALE; NONHUMAN; POWER SPECTRAL ANALYSIS; SPECIES DIFFERENCE; SPECTROSCOPY; TELEMETRY; VAGUS TONE;

BEAGLE DOGS; CYNOMOLGUS MONKEYS; HEART RATE VARIABILITY; POWER SPECTRAL ANALYSIS; SAFETY PHARMACOLOGY; TELEMETRY;

ANIMALS; AUTONOMIC NERVOUS SYSTEM; DOGS; ELECTROCARDIOGRAPHY; FEMALE; HEART RATE; MACACA FASCICULARIS; MALE; MODELS, ANIMAL; SPECIES SPECIFICITY; TELEMETRY; TOXICITY TESTS;

CANIS FAMILIARIS; MACACA FASCICULARIS; PRIMATES; RODENTIA;

EID: 84880038848     PISSN: 10568719     EISSN: 1873488X     Source Type: Journal    
DOI: 10.1016/j.vascn.2013.02.005     Document Type: Article

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