Age-related differences of QT interval and autonomic nervous system activity in female cynomolgus monkeys

Journal of Pharmacological and Toxicological Methods

Volumn 60, Issue 3, 2009, Pages 288-295

  Ishizaka, Tomomichi ^a   Yoshimatsu, Yu ^a   Ozawa, Minori ^a   Kimotsuki, Tomofumi ^a   Takasaki, Wataru ^a   Manabe, Sunao ^a   Yasuda, Mitsuya ^a  

^a DAIICHI SANKYO CO   (Japan)

Author keywords

Age; Autonomic nervous system activity; Cynomolgus monkey; Methods; QT interval; QT interval prolongation; Sotalol

Indexed keywords

SOTALOL;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; AUTONOMIC NERVOUS SYSTEM FUNCTION; BLOOD SAMPLING; CONTROLLED STUDY; DRUG BLOOD LEVEL; ELECTROCARDIOGRAM; FEMALE; HEART RATE VARIABILITY; HOLTER MONITORING; MAXIMUM PLASMA CONCENTRATION; MEASUREMENT; MONKEY; NONHUMAN; QT INTERVAL; QT PROLONGATION; SPECTROSCOPY;

AGE FACTORS; AGING; ANIMALS; AUTONOMIC NERVOUS SYSTEM; ELECTROCARDIOGRAPHY; FEMALE; LONG QT SYNDROME; MACACA FASCICULARIS;

ANIMALIA; MACACA FASCICULARIS;

EID: 70449526385     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vascn.2009.06.003     Document Type: Article

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