메뉴 건너뛰기




Volumn 190, Issue 2, 2013, Pages 790-798

SaRNA guided iNOS Up-regulation improves erectile function of diabetic rats

Author keywords

diabetes mellitus, experimental; erectile dysfunction; nitric oxide synthase type II; penis; RNA

Indexed keywords

ADENOVIRUS VECTOR; CYCLIC GMP; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; RNA; SMALL ACTIVATING RNA; UNCLASSIFIED DRUG;

EID: 84880037247     PISSN: 00225347     EISSN: 15273792     Source Type: Journal    
DOI: 10.1016/j.juro.2013.03.043     Document Type: Article
Times cited : (34)

References (30)
  • 1
    • 0028036149 scopus 로고
    • Impotence and its medical and psychosocial correlates: Results of the Massachusetts Male Aging Study
    • H.A. Feldman, I. Goldstein, D.G. Hatzichristou Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study J Urol 151 1994 54
    • (1994) J Urol , vol.151 , pp. 54
    • Feldman, H.A.1    Goldstein, I.2    Hatzichristou, D.G.3
  • 2
    • 0042167567 scopus 로고    scopus 로고
    • Do impotent men with diabetes have more severe erectile dysfunction and worse quality of life than the general population of impotent patients? Results from the Exploratory Comprehensive Evaluation of Erectile Dysfunction (ExCEED) database
    • D.F. Penson, D.M. Latini, D.P. Lubeck Do impotent men with diabetes have more severe erectile dysfunction and worse quality of life than the general population of impotent patients? Results from the Exploratory Comprehensive Evaluation of Erectile Dysfunction (ExCEED) database Diabetes Care 26 2003 1093
    • (2003) Diabetes Care , vol.26 , pp. 1093
    • Penson, D.F.1    Latini, D.M.2    Lubeck, D.P.3
  • 3
    • 61849114563 scopus 로고    scopus 로고
    • Assessment of erectile dysfunction in diabetic patients
    • F.B. Hamdan, H.Y. Al-Matubsi Assessment of erectile dysfunction in diabetic patients Int J Androl 32 2009 176
    • (2009) Int J Androl , vol.32 , pp. 176
    • Hamdan, F.B.1    Al-Matubsi, H.Y.2
  • 4
    • 77649123864 scopus 로고    scopus 로고
    • Molecular targets for diabetes mellitus-associated erectile dysfunction
    • E. Yohannes, J. Chang, M.T. Tar Molecular targets for diabetes mellitus-associated erectile dysfunction Mol Cell Proteomics 9 2010 565
    • (2010) Mol Cell Proteomics , vol.9 , pp. 565
    • Yohannes, E.1    Chang, J.2    Tar, M.T.3
  • 5
    • 0037349838 scopus 로고    scopus 로고
    • Pharmacological management of erectile dysfunction
    • F. Montorsi, A. Salonia, F. Dehó Pharmacological management of erectile dysfunction BJU Int 91 2003 446
    • (2003) BJU Int , vol.91 , pp. 446
    • Montorsi, F.1    Salonia, A.2    Dehó, F.3
  • 6
    • 77953948992 scopus 로고    scopus 로고
    • Guidelines on male sexual dysfunction: Erectile dysfunction and premature ejaculation
    • K. Hatzimouratidis, E. Amar, I. Eardley Guidelines on male sexual dysfunction: erectile dysfunction and premature ejaculation Eur Urol 57 2010 804
    • (2010) Eur Urol , vol.57 , pp. 804
    • Hatzimouratidis, K.1    Amar, E.2    Eardley, I.3
  • 7
    • 21344455539 scopus 로고    scopus 로고
    • Gene therapy for erectile dysfunction
    • M. Kendirci, S. Gur, S.C. Sikka Gene therapy for erectile dysfunction Front Biosci 10 2005 2758
    • (2005) Front Biosci , vol.10 , pp. 2758
    • Kendirci, M.1    Gur, S.2    Sikka, S.C.3
  • 8
    • 0037568492 scopus 로고    scopus 로고
    • Nitric oxide synthase gene transfer for erectile dysfunction in a rat model
    • M.B. Chancellor, S. Tirney, C.E. Mattes Nitric oxide synthase gene transfer for erectile dysfunction in a rat model BJU Int 91 2003 691
    • (2003) BJU Int , vol.91 , pp. 691
    • Chancellor, M.B.1    Tirney, S.2    Mattes, C.E.3
  • 9
    • 9644299891 scopus 로고    scopus 로고
    • Molecular pathophysiology and gene therapy of aging-related erectile dysfunction
    • N.F. Gonzalez-Cadavid, J. Rajfer Molecular pathophysiology and gene therapy of aging-related erectile dysfunction Exp Gerontol 39 2004 1705
    • (2004) Exp Gerontol , vol.39 , pp. 1705
    • Gonzalez-Cadavid, N.F.1    Rajfer, J.2
  • 10
    • 33750613462 scopus 로고    scopus 로고
    • Gene therapy for erectile dysfunction: Fact or fiction?
    • M. Kendirci, P.E. Teloken, H.C. Champion Gene therapy for erectile dysfunction: fact or fiction? Eur Urol 50 2006 1208
    • (2006) Eur Urol , vol.50 , pp. 1208
    • Kendirci, M.1    Teloken, P.E.2    Champion, H.C.3
  • 11
    • 47949131904 scopus 로고    scopus 로고
    • Gene therapy via inducible nitric oxide synthase: A tool for the treatment of a diverse range of pathological conditions
    • H.O. McCarthy, J.A. Coulter, T. Robson Gene therapy via inducible nitric oxide synthase: a tool for the treatment of a diverse range of pathological conditions J Pharm Pharmacol 60 2008 999
    • (2008) J Pharm Pharmacol , vol.60 , pp. 999
    • McCarthy, H.O.1    Coulter, J.A.2    Robson, T.3
  • 12
    • 33751251990 scopus 로고    scopus 로고
    • Small dsRNAs induce transcriptional activation in human cells
    • L.C. Li, S.T. Okino, H. Zhao Small dsRNAs induce transcriptional activation in human cells Proc Natl Acad Sci U S A 103 2006 17337
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 17337
    • Li, L.C.1    Okino, S.T.2    Zhao, H.3
  • 13
    • 43949099936 scopus 로고    scopus 로고
    • Up-regulation of p21WAF1/Cip1 by saRNA induces G1-phase arrest and apoptosis in T24 human bladder cancer cells
    • K. Yang, X.Y. Zheng, J. Qin Up-regulation of p21WAF1/Cip1 by saRNA induces G1-phase arrest and apoptosis in T24 human bladder cancer cells Cancer Lett 265 2008 206
    • (2008) Cancer Lett , vol.265 , pp. 206
    • Yang, K.1    Zheng, X.Y.2    Qin, J.3
  • 15
    • 84870365148 scopus 로고    scopus 로고
    • Targeted p21WAF1/CIP1 activation by RNAa inhibits hepatocellular carcinoma cells
    • M. Kosaka, M.R. Kang, G. Yang Targeted p21WAF1/CIP1 activation by RNAa inhibits hepatocellular carcinoma cells Nucleic Acid Ther 22 2012 335
    • (2012) Nucleic Acid Ther , vol.22 , pp. 335
    • Kosaka, M.1    Kang, M.R.2    Yang, G.3
  • 16
    • 80053573084 scopus 로고    scopus 로고
    • Up-regulation of VEGF by small activator RNA in human corpus cavernosum smooth muscle cells
    • R. Chen, T. Wang, K. Rao Up-regulation of VEGF by small activator RNA in human corpus cavernosum smooth muscle cells J Sex Med 8 2011 2773
    • (2011) J Sex Med , vol.8 , pp. 2773
    • Chen, R.1    Wang, T.2    Rao, K.3
  • 17
    • 34447544338 scopus 로고    scopus 로고
    • Inhibition of telomerase RNA (hTR) in cervical cancer by adenovirus-delivered siRNA
    • Y. Li, H. Li, G. Yao Inhibition of telomerase RNA (hTR) in cervical cancer by adenovirus-delivered siRNA Cancer Gene Ther 14 2007 748
    • (2007) Cancer Gene Ther , vol.14 , pp. 748
    • Li, Y.1    Li, H.2    Yao, G.3
  • 18
    • 33947230295 scopus 로고    scopus 로고
    • Differential expression of neurotrophins in penises of streptozotocin-induced diabetic rats
    • Y. Chen, R. Yang, L. Yao Differential expression of neurotrophins in penises of streptozotocin-induced diabetic rats J Androl 28 2007 306
    • (2007) J Androl , vol.28 , pp. 306
    • Chen, Y.1    Yang, R.2    Yao, L.3
  • 19
    • 84860308162 scopus 로고    scopus 로고
    • Expression of oxytocin receptor in diabetic rat penis
    • M. Li, T. Wang, S. Guo Expression of oxytocin receptor in diabetic rat penis Andrologia 44 suppl. 2012 716
    • (2012) Andrologia , vol.44 , Issue.SUPPL. , pp. 716
    • Li, M.1    Wang, T.2    Guo, S.3
  • 20
    • 78651266917 scopus 로고    scopus 로고
    • Age-related changes in kallikreins-kinins system in rat corpus cavernosum
    • T. Wang, Z.H. Wan, J.H. Liu Age-related changes in kallikreins-kinins system in rat corpus cavernosum Int J Androl 34 2011 33
    • (2011) Int J Androl , vol.34 , pp. 33
    • Wang, T.1    Wan, Z.H.2    Liu, J.H.3
  • 21
    • 33751099034 scopus 로고    scopus 로고
    • RNAi therapeutics: A potential new class of pharmaceutical drugs
    • D. Bumcrot, M. Manoharan, V. Koteliansky RNAi therapeutics: a potential new class of pharmaceutical drugs Nat Chem Biol 2 2006 711
    • (2006) Nat Chem Biol , vol.2 , pp. 711
    • Bumcrot, D.1    Manoharan, M.2    Koteliansky, V.3
  • 22
    • 70349239135 scopus 로고    scopus 로고
    • Efficient regulation of VEGF expression by promoter-targeted lentiviral shRNAs based on epigenetic mechanism: A novel example of epigenetherapy
    • M.P. Turunen, T. Lehtola, S.E. Heinonen Efficient regulation of VEGF expression by promoter-targeted lentiviral shRNAs based on epigenetic mechanism: a novel example of epigenetherapy Circ Res 105 2009 604
    • (2009) Circ Res , vol.105 , pp. 604
    • Turunen, M.P.1    Lehtola, T.2    Heinonen, S.E.3
  • 23
    • 80053004837 scopus 로고    scopus 로고
    • Optimizing vaccine-induced CD8(+) T-cell immunity: Focus on recombinant adenovirus vectors
    • J.D. Bassett, S.L. Swift, J.L. Bramson Optimizing vaccine-induced CD8(+) T-cell immunity: focus on recombinant adenovirus vectors Expert Rev Vaccines 10 2011 1307
    • (2011) Expert Rev Vaccines , vol.10 , pp. 1307
    • Bassett, J.D.1    Swift, S.L.2    Bramson, J.L.3
  • 24
    • 27944448794 scopus 로고    scopus 로고
    • The pleiotropic effects of inducible nitric oxide synthase (iNOS) on the physiology and pathology of penile erection
    • N.F. Gonzalez-Cadavid, J. Rajfer The pleiotropic effects of inducible nitric oxide synthase (iNOS) on the physiology and pathology of penile erection Curr Pharm Des 11 2005 4041
    • (2005) Curr Pharm des , vol.11 , pp. 4041
    • Gonzalez-Cadavid, N.F.1    Rajfer, J.2
  • 25
    • 77956290082 scopus 로고    scopus 로고
    • The genetic inactivation of inducible nitric oxide synthase (iNOS) intensifies fibrosis and oxidative stress in the penile corpora cavernosa in type 1 diabetes
    • M.G. Ferrini, S. Rivera, J. Moon The genetic inactivation of inducible nitric oxide synthase (iNOS) intensifies fibrosis and oxidative stress in the penile corpora cavernosa in type 1 diabetes J Sex Med 7 2010 3033
    • (2010) J Sex Med , vol.7 , pp. 3033
    • Ferrini, M.G.1    Rivera, S.2    Moon, J.3
  • 26
    • 0030978643 scopus 로고    scopus 로고
    • Cloning of rat and human inducible penile nitric oxide synthase Application for gene therapy of erectile dysfunction
    • H. Garbán, D. Marquez, T. Magee Cloning of rat and human inducible penile nitric oxide synthase Application for gene therapy of erectile dysfunction Biol Reprod 56 1997 954
    • (1997) Biol Reprod , vol.56 , pp. 954
    • Garbán, H.1    Marquez, D.2    Magee, T.3
  • 27
    • 0035078843 scopus 로고    scopus 로고
    • Nitric oxide synthase gene therapy for erectile dysfunction: Comparison of plasmid, adenovirus, and adenovirus-transduced myoblast vectors
    • S. Tirney, C.E. Mattes, N. Yoshimura Nitric oxide synthase gene therapy for erectile dysfunction: comparison of plasmid, adenovirus, and adenovirus-transduced myoblast vectors Mol Urol 5 2001 37
    • (2001) Mol Urol , vol.5 , pp. 37
    • Tirney, S.1    Mattes, C.E.2    Yoshimura, N.3
  • 28
    • 33748296220 scopus 로고    scopus 로고
    • Effect of endothelial cell-based iNOS gene transfer on cavernosal eNOS expression and mouse erectile responses
    • H. Wessells, T.H. Teal, I.P. Luttrell Effect of endothelial cell-based iNOS gene transfer on cavernosal eNOS expression and mouse erectile responses Int J Impot Res 18 2006 438
    • (2006) Int J Impot Res , vol.18 , pp. 438
    • Wessells, H.1    Teal, T.H.2    Luttrell, I.P.3
  • 29
    • 6344243407 scopus 로고    scopus 로고
    • Gene transfer of inducible nitric oxide synthase complementary DNA regresses the fibrotic plaque in an animal model of Peyronie's disease
    • H.H. Davila, T.R. Magee, D. Vernet Gene transfer of inducible nitric oxide synthase complementary DNA regresses the fibrotic plaque in an animal model of Peyronie's disease Biol Reprod 71 2004 1568
    • (2004) Biol Reprod , vol.71 , pp. 1568
    • Davila, H.H.1    Magee, T.R.2    Vernet, D.3
  • 30
    • 84864601291 scopus 로고    scopus 로고
    • Selective vulnerability of synaptic signaling and metabolism to nitrosative stress
    • A.A. Mongin, P. Dohare, D. Jourd'heuil Selective vulnerability of synaptic signaling and metabolism to nitrosative stress Antioxid Redox Signal 17 2012 992
    • (2012) Antioxid Redox Signal , vol.17 , pp. 992
    • Mongin, A.A.1    Dohare, P.2    Jourd'Heuil, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.