Knockdown of nucleophosmin by RNA interference reverses multidrug resistance in resistant leukemic HL-60 cells

Immunobiology

Volumn 218, Issue 9, 2013, Pages 1147-1154

  Lin, Minhui ^a   Hu, Jianda ^a   Liu, Tingbo ^a   Li, Jing ^a   Chen, Buyuan ^a   Chen, Xinji ^a  

^a FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

Leukemia; Multidrug resistance; Nucleophosmin; RNA interference

Indexed keywords

DAUNORUBICIN; DOXORUBICIN; ETOPOSIDE; NUCLEOPHOSMIN; SHORT HAIRPIN RNA; VINCRISTINE;

APOPTOSIS; ARTICLE; CANCER RESISTANCE; CELL CYCLE G0 PHASE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRAIN HL 60; CELL TRANSFORMATION; CHEMOSENSITIVITY; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; G1 PHASE CELL CYCLE CHECKPOINT; GENE EXPRESSION REGULATION; GENE TARGETING; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; IC 50; LEUKEMIA CELL; MULTIDRUG RESISTANCE; NPM GENE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE;

12-O-TETRADECANOYLPHORBOL-13-ACETATE; ACUTE MYELOID LEUKEMIA; ADR; ADRIAMYCIN; AML; DAUNORUBICIN; DNR; ECL; ENHANCED CHEMILUMINESCENCE; ETOPOSIDE; HALF INHIBITORY CONCENTRATION; IC50; LENTIVIRUS; LEUKEMIA; LV; MDR; MULTIDRUG RESISTANCE; NBT; NITROBLUE TETRAZOLIUM REDUCTION; NPM; NUCLEOPHOSMIN; PI; PROPIDIUM IODIDE; QRT-PCR; QUANTITATIVE REAL-TIME REVERSE TRANSCRIPTION CHAIN REACTION; RELATIVE REVERSAL RATE; RNA INTERFERENCE; RNAI; RR; SHORT HAIRPIN RNA; SHRNA; TPA; VCR; VINCRISTINE; VP16;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL DIFFERENTIATION; CELL GROWTH PROCESSES; DOXORUBICIN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; GENE KNOCKDOWN TECHNIQUES; GENETIC VECTORS; HL-60 CELLS; HUMANS; LENTIVIRUS; LEUKEMIA, PROMYELOCYTIC, ACUTE; NUCLEAR PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84880036442     PISSN: 01712985     EISSN: 18783279     Source Type: Journal    
DOI: 10.1016/j.imbio.2013.04.001     Document Type: Article

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