Interleukin-4 deficiency inducesmild preeclampsia inmice

Journal of Hypertension

Volumn 31, Issue 7, 2013, Pages 1414-1423

  Chatterjee, Piyali ^a   Kopriva, Shelley E ^a   Chiasson, Valorie L ^a   Young, Kristina J ^a   Tobin, Richard P ^a   Newell Rogers, Karen ^a   Mitchell, Brett M ^a  

^a White Memorial Hospital   (United States)

Author keywords

Anti inflammatory; Cytokines; Endothelial function; Pregnancy; Pro inflammatory; SBP

Indexed keywords

INTERLEUKIN 4; POLYINOSINIC POLYCYTIDYLIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BORDERLINE HYPERTENSION; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; ENDOTHELIAL DYSFUNCTION; FEMALE; IMMUNE SYSTEM; IMMUNOCOMPETENT CELL; INFLAMMATION; INTERLEUKIN 4 DEFICIENCY; NONHUMAN; PLACENTA DISORDER; PREECLAMPSIA; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN URINE LEVEL; PROTEINURIA; RAT; SPLEEN CELL;

EID: 84880034948     PISSN: 02636352     EISSN: 14735598     Source Type: Journal    
DOI: 10.1097/HJH.0b013e328360ae6c     Document Type: Article

References (46)

1. Sibai BM. Magnesium sulfate prophylaxis in preeclampsia: lessons learned from recent trials. Am J Obstet Gynecol 2004; 190:1520-1526.
2. Redman CW, Sacks GP, Sargent IL. Preeclampsia: an excessive maternal inflammatory response to pregnancy. Am J Obstet Gynecol 1999; 180:499-506.
3. Sibai B, Dekker G, Kupferminc M. Preeclampsia. Lancet 2005; 365:785-799.
4. Warning JC, McCracken SA, Morris JM. A balancing act: mechanisms by which the fetus avoids rejection by the maternal immune system. Reproduction 2011; 141:715-724.
5. Saito S, Sakai M, Sasaki Y, Tanebe K, Tsuda H, Michimata T. Quantitative analysis of peripheral blood Th0, Th1, Th2 and the Th1:Th2 cell ratio during normal human pregnancy and preeclampsia. Clin Exp Immunol 1999; 117:550-555.
6. Saito S, Tsukaguchi N, Hasegawa T, Michimata T, Tsuda H, Narita N. Distribution of Th1, Th2, and Th0 and the Th1/Th2 cell ratios in human peripheral and endometrial T cells. Am J Reprod Immunol 1999; 42:240-245.
7. Kalinderis M, Papanikolaou A, Kalinderi K, Ioannidou E, Giannoulis C, Karagiannis V, et al. Elevated serum levels of interleukin-6, interleukin-1beta and human chorionic gonadotropin in preeclampsia. Am J Reprod Immunol 2011; 66:468-475.
8. Szarka A, Rigo J Jr., Lazar L, Beko G, Molvarec A. Circulating cytokines, chemokines and adhesion molecules in normal pregnancy and preeclampsia determined by multiplex suspension array. BMC Immunol 2010; 11:59.
9. Arriaga-Pizano L, Jimenez-Zamudio L, Vadillo-Ortega F, Martinez-Flores A, Herrerias-Canedo T, Hernandez-Guerrero C. The predominant Th1 cytokine profile in maternal plasma of preeclamptic women is not reflected in the choriodecidual and fetal compartments. J Soc Gynecol Investig 2005; 12:335-342.
10. Jonsson Y, Ruber M, Matthiesen L, Berg G, Nieminen K, Sharma S, et al. Cytokine mapping of sera from women with preeclampsia and normal pregnancies. J Reprod Immunol 2006; 70:83-91.
11. Chatterjee P, Chiasson VL, Kopriva SE, Young KJ, Chatterjee V, Jones KA, Mitchell BM. Interleukin 10 deficiency exacerbates Toll-like receptor 3-induced preeclampsia-like symptoms in mice. Hypertension 2011; 58:489-496.
12. de Moraes-Pinto MI, Vince GS, Flanagan BF, Hart CA, Johnson PM. Localization of IL-4 and IL-4 receptors in the human term placenta, decidua and amniochorionic membranes. Immunology 1997; 90:87-94.
13. Haynes MK, Jackson LG, Tuan RS, Shepley KJ, Smith JB. Cytokine production in first trimester chorionic villi: detection of mRNAs and protein products in situ. Cell Immunol 1993; 151:300-308.
14. Mosmann TR, Coffman RL. TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties. Annu Rev Immunol 1989; 7:145-173.
15. Bonney EA. Maternal tolerance is not critically dependent on interleukin-4. Immunology 2001; 103:382-389.
16. Sado T, Naruse K, Noguchi T, Haruta S, Yoshida S, Tanase Y, et al. Inflammatory pattern recognition receptors and their ligands: factors contributing to the pathogenesis of preeclampsia. Inflamm Res 2011; 60:509-520.
17. Patni S, Wynen LP, Seager AL, Morgan G, White JO, Thornton CA. Expression and activity of Toll-like receptors 1-9 in the human term placenta and changes associated with labor at term. Biol Reprod 2009; 80:243-248.
18. Laresgoiti-Servitje E, Gomez-Lopez N, Olson DM. An immunological insight into the origins of preeclampsia. Hum Reprod Update 2010; 16:510-524.
19. Arechavaleta-Velasco F, Ma Y, Zhang J, McGrath CM, Parry S. Adenoassociated virus-2 (AAV-2) causes trophoblast dysfunction, and placental AAV-2 infection is associated with preeclampsia. Am J Pathol 2006; 168:1951-1959.
20. Rustveld LO, Kelsey SF, Sharma R. Association between maternal infections and preeclampsia: a systematic review of epidemiologic studies. Matern Child Health J 2008; 12:223-242.
21. Tinsley JH, Chiasson VL, Mahajan A, Young KJ, Mitchell BM. Toll-like receptor 3 activation during pregnancy elicits preeclampsia-like symptoms in rats. Am J Hypertens 2009; 22:1314-1319.
22. Tinsley JH, Chiasson VL, South S, Mahajan A, Mitchell BM. Immunosuppression improves blood pressure and endothelial function in a rat model of pregnancy-induced hypertension. Am J Hypertens 2009; 22:1107-1114.
23. Kawai T, Akira S. Signaling to NF-kappaB by Toll-like receptors. Trends Mol Med 2007; 13:460-469.
24. Kawai T, Akira S. Toll-like receptors and their crosstalk with other innate receptors in infection and immunity. Immunity 2011; 34:637-650.
25. Chiasson VL, Talreja D, Young KJ, Chatterjee P, Banes-Berceli AK, Mitchell BM. FK506 binding protein 12 deficiency in endothelial and hematopoietic cells decreases regulatory T cells and causes hypertension. Hypertension 2011; 57:1167-1175.
26. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001; 25:402-408.
27. Raghupathy R. Th1-type immunity is incompatible with successful pregnancy. Immunol Today 1997; 18:478-482.
28. Wang Z, Zou H, Yu Y, Song Y. Monoclonal antibody to intercellular adhesion molecule-1 as a novel therapy for preeclampsia: preliminary results from a rat model. J Matern Fetal Neona 2012; 25:855-859.
29. Karthikeyan VJ, Lip GY. Endothelial damage/dysfunction and hypertension in pregnancy. Front Biosci (Elite Ed) 2011; 3:1100-1108.
30. Roberts JM, Taylor RN, Musci TJ, Rodgers GM, Hubel CA, McLaughlin MK. Preeclampsia: an endothelial cell disorder. Am J Obstet Gynecol 1989; 161:1200-1204.
31. Seder RA, Paul WE, Davis MM, Fazekas de St Groth B. The presence of interleukin 4 during in vitro priming determines the lymphokineproducing potential of CD4 T cells from T cell receptor transgenic mice. J Exp Med 1992; 176:1091-1098.
32. Vitetta ES, Ohara J, Myers CD, Layton JE, Krammer PH, Paul WE. Serological, biochemical, and functional identity of B cell-stimulatory factor 1 and B cell differentiation factor for IgG1. J Exp Med 1985; 162:1726-1731.
33. Illera VA, Perandones CE, Stunz LL, Mower DA Jr., Ashman RF. Apoptosis in splenic B lymphocytes. Regulation by protein kinase C and IL-4. J Immunol 1993; 151:2965-2973.
34. Lutz MB, Schnare M, Menges M, Rossner S, Rollinghoff M, Schuler G, et al. Differential functions of IL-4 receptor types I and II for dendritic cell maturation and IL-12 production and their dependency on GM-CSF. J Immunol 2002; 169:3574-3580.
35. Yanagida M, Fukamachi H, Ohgami K, Kuwaki T, Ishii H, Uzumaki H, et al. Effects of T-helper 2-type cytokines, interleukin-3 (IL-3), IL-4, IL-5, and IL-6 on the survival of cultured human mast cells. Blood 1995; 86:3705-3714.
36. Zubiaga AM, Munoz E, Huber BT. IL-4 and IL-2 selectively rescue Th cell subsets from glucocorticoid-induced apoptosis. J Immunol 1992; 149:107-112.
37. Toldi G, Svec P, Vasarhelyi B, Meszaros G, Rigo J, Tulassay T, et al. Decreased number of FoxP3 regulatory T cells in preeclampsia. Acta Obstet Gynecol Scand 2008; 87:1229-1233.
38. Santner-Nanan B, Peek MJ, Khanam R, Richarts L, Zhu E, Fazekas de St Groth B, et al. Systemic increase in the ratio between FoxP3 and IL-17-producing CD4 T cells in healthy pregnancy but not in preeclampsia. J Immunol 2009; 183:7023-7030.
39. Prins JR, Boelens HM, Heimweg J, Van der Heide S, Dubois AE, Van Oosterhout AJ, et al. Preeclampsia is associated with lower percentages of regulatory T cells in maternal blood. Hypertens Pregnancy 2009; 28:300-311.
40. Jensen F, Wallukat G, Herse F, Budner O, El-Mousleh T, Costa SD, et al. CD19CD5 cells as indicators of preeclampsia. Hypertension 2012; 59:861-868.
41. Bergmann A, Ahmad S, Cudmore M, Gruber AD, Wittschen P, Lindenmaier W, et al. Reduction of circulating soluble Flt-1 alleviates preeclampsia-like symptoms in a mouse model. J Cell Mol Med 2010; 14:1857-1867.
42. Miossec P. Anti-inflammatory properties of interleukin-4. Rev Rhum Ed Fr 1993; 60:119-124.
43. Mueller R, Krahl T, Sarvetnick N. Pancreatic expression of interleukin-4 abrogates insulitis and autoimmune diabetes in nonobese diabetic (NOD) mice. J Exp Med 1996; 184:1093-1099.
44. ZamoranoJ,WangHY,WangLM, PierceJH,KeeganAD. IL-4protectscells from apoptosis via the insulin receptor substrate pathway and a second independent signaling pathway. J Immunol 1996; 157:4926-4934.
45. Woods JM, Katschke KJ, Volin MV, Ruth JH, Woodruff DC, Amin MA, et al. IL-4 adenoviral gene therapy reduces inflammation, proinflammatory cytokines, vascularization, and bony destruction in rat adjuvant-induced arthritis. J Immunol 2001; 166:1214-1222.
46. Ghoreschi K, Thomas P, Breit S, Dugas M, Mailhammer R, van Eden W, et al. Interleukin-4 therapy of psoriasis induces Th2 responses and improves human autoimmune disease. Nat Med 2003; 9:40-46.