The gottingen minipig is a model of the hematopoietic acute radiation syndrome: G-colony stimulating factor stimulates hematopoiesis and enhances survival from lethal total-body γ-irradiation

International Journal of Radiation Oncology Biology Physics

Volumn 86, Issue 5, 2013, Pages 986-992

  Moroni, Maria ^a   Ngudiankama, Barbara F ^b   Christensen, Christine ^a   Olsen, Cara H ^a   Owens, Rossitsa ^a   Lombardini, Eric D ^c   Holt, Rebecca K ^a   Whitnall, Mark H ^a  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c ARMED FORCES RESEARCH INSTITUTE OF MEDICAL SCIENCES   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE RADIATION SYNDROME; ANIMAL MODEL; DRUG TESTING; GRANULOCYTE-COLONY STIMULATING FACTOR; HEMATOPOIETIC PROGENITOR CELLS; METHODS AND MATERIALS; PATHOPHYSIOLOGY; TOTAL BODY IRRADIATION;

BLOOD; IRRADIATION; MOLECULAR BIOLOGY;

RADIATION;

GRANULOCYTE COLONY STIMULATING FACTOR; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR;

ACUTE RADIATION SYNDROME; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; CELL LOSS; CONTROLLED STUDY; GAMMA IRRADIATION; HEMATOPOIESIS; HEMATOPOIETIC ACUTE RADIATION SYNDROME; HEMATOPOIETIC STEM CELL; LETHAL TOTAL BODY GAMMA IRRADIATION; MACROPHAGE; MALE; MINIPIG; MONOCYTE; NEUTROPENIA; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RADIATION DOSE; SURVIVAL;

ACUTE RADIATION SYNDROME; ANIMALS; C-REACTIVE PROTEIN; DISEASE MODELS, ANIMAL; DRUG EVALUATION, PRECLINICAL; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL MOBILIZATION; HUMANS; MACROPHAGES; MALE; MONOCYTES; NEUTROPENIA; ORGANS AT RISK; RECOMBINANT PROTEINS; REPRODUCIBILITY OF RESULTS; SWINE; SWINE, MINIATURE; WHOLE-BODY IRRADIATION;

EID: 84879999764     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2013.04.041     Document Type: Article

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