메뉴 건너뛰기




Volumn 133, Issue 6, 2013, Pages 1345-1356

Sox21 inhibits glioma progression in vivo by forming complexes with Sox2 and stimulating aberrant differentiation

Author keywords

brain tumors; glioma; S100; Sox2; Sox21

Indexed keywords

2',3' CYCLIC NUCLEOTIDE 3' PHOSPHODIESTERASE; DOXYCYCLINE; TETRACYCLINE; TRANSCRIPTION FACTOR SOX; TRANSCRIPTION FACTOR SOX2; TRANSCRIPTION FACTOR SOX21; UNCLASSIFIED DRUG;

EID: 84879992279     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.28147     Document Type: Article
Times cited : (26)

References (45)
  • 2
    • 4944255253 scopus 로고    scopus 로고
    • Genetic pathways to glioblastoma: A population-based study
    • Ohgaki H, Dessen P, Jourde B, et al. Genetic pathways to glioblastoma: a population-based study. Cancer Res 2004; 64: 6892-9.
    • (2004) Cancer Res , vol.64 , pp. 6892-6899
    • Ohgaki, H.1    Dessen, P.2    Jourde, B.3
  • 3
    • 57749091753 scopus 로고    scopus 로고
    • Cancer stem cells are enriched in the side population cells in a mouse model of glioma
    • Harris MA, Yang H, Low BE, et al. Cancer stem cells are enriched in the side population cells in a mouse model of glioma. Cancer Res 2008; 68: 10051-9.
    • (2008) Cancer Res , vol.68 , pp. 10051-10059
    • Harris, M.A.1    Yang, H.2    Low, B.E.3
  • 4
    • 0141842674 scopus 로고    scopus 로고
    • Identification of a cancer stem cell in human brain tumors
    • Singh SK, Clarke ID, Terasaki M, et al. Identification of a cancer stem cell in human brain tumors. Cancer Res 2003; 63: 5821-8.
    • (2003) Cancer Res , vol.63 , pp. 5821-5828
    • Singh, S.K.1    Clarke, I.D.2    Terasaki, M.3
  • 5
    • 9244241576 scopus 로고    scopus 로고
    • Identification of human brain tumour initiating cells
    • Singh SK, Hawkins C, Clarke ID, et al. Identification of human brain tumour initiating cells. Nature 2004; 432: 396-401.
    • (2004) Nature , vol.432 , pp. 396-401
    • Singh, S.K.1    Hawkins, C.2    Clarke, I.D.3
  • 6
    • 0025328296 scopus 로고
    • A gene mapping to the sex-determining region of the mouse y chromosome is a member of a novel family of embryonically expressed genes
    • Gubbay J, Collignon J, Koopman P, et al. A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genes. Nature 1990; 346: 245-50.
    • (1990) Nature , vol.346 , pp. 245-250
    • Gubbay, J.1    Collignon, J.2    Koopman, P.3
  • 7
    • 0033559518 scopus 로고    scopus 로고
    • From head to toes: The multiple facets of Sox proteins
    • Wegner M,. From head to toes: the multiple facets of Sox proteins. Nucleic Acids Res 1999; 27: 1409-20.
    • (1999) Nucleic Acids Res , vol.27 , pp. 1409-1420
    • Wegner, M.1
  • 8
    • 0032789437 scopus 로고    scopus 로고
    • Two distinct subgroups of Group B Sox genes for transcriptional activators and repressors: Their expression during embryonic organogenesis of the chicken
    • Uchikawa M, Kamachi Y, Kondoh H,. Two distinct subgroups of Group B Sox genes for transcriptional activators and repressors: their expression during embryonic organogenesis of the chicken. Mech Dev 1999; 84: 103-20.
    • (1999) Mech Dev , vol.84 , pp. 103-120
    • Uchikawa, M.1    Kamachi, Y.2    Kondoh, H.3
  • 9
    • 79955418188 scopus 로고    scopus 로고
    • Forced expression of Sox21 inhibits Sox2 and induces apoptosis in human glioma cells
    • Ferletta M, Caglayan D, Mokvist L, et al. Forced expression of Sox21 inhibits Sox2 and induces apoptosis in human glioma cells. Int J Cancer 2011; 129: 45-60.
    • (2011) Int J Cancer , vol.129 , pp. 45-60
    • Ferletta, M.1    Caglayan, D.2    Mokvist, L.3
  • 10
    • 53049088719 scopus 로고    scopus 로고
    • Having it both ways: Sox protein function between conservation and innovation
    • Guth SI, Wegner M,. Having it both ways: Sox protein function between conservation and innovation. Cell Mol Life Sci 2008; 65: 3000-18.
    • (2008) Cell Mol Life Sci , vol.65 , pp. 3000-3018
    • Guth, S.I.1    Wegner, M.2
  • 11
    • 13844302847 scopus 로고    scopus 로고
    • SOX2, a persistent marker for multipotential neural stem cells derived from embryonic stem cells, the embryo or the adult
    • Ellis P, Fagan BM, Magness ST, et al. SOX2, a persistent marker for multipotential neural stem cells derived from embryonic stem cells, the embryo or the adult. Dev Neurosci 2004; 26: 148-65.
    • (2004) Dev Neurosci , vol.26 , pp. 148-165
    • Ellis, P.1    Fagan, B.M.2    Magness, S.T.3
  • 12
    • 4444378766 scopus 로고    scopus 로고
    • Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain
    • Ferri AL, Cavallaro M, Braida D, et al. Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain. Development 2004; 131: 3805-19.
    • (2004) Development , vol.131 , pp. 3805-3819
    • Ferri, A.L.1    Cavallaro, M.2    Braida, D.3
  • 13
    • 9944266165 scopus 로고    scopus 로고
    • Chromatin remodeling and histone modification in the conversion of oligodendrocyte precursors to neural stem cells
    • Kondo T, Raff M,. Chromatin remodeling and histone modification in the conversion of oligodendrocyte precursors to neural stem cells. Genes Dev 2004; 18: 2963-72.
    • (2004) Genes Dev , vol.18 , pp. 2963-2972
    • Kondo, T.1    Raff, M.2
  • 14
    • 0242353154 scopus 로고    scopus 로고
    • Vertebrate neurogenesis is counteracted by Sox1-3 activity
    • Bylund M, Andersson E, Novitch BG, et al. Vertebrate neurogenesis is counteracted by Sox1-3 activity. Nat Neurosci 2003; 6: 1162-8.
    • (2003) Nat Neurosci , vol.6 , pp. 1162-1168
    • Bylund, M.1    Andersson, E.2    Novitch, B.G.3
  • 15
    • 23044451795 scopus 로고    scopus 로고
    • Sox21 promotes the progression of vertebrate neurogenesis
    • Sandberg M, Kallstrom M, Muhr J,. Sox21 promotes the progression of vertebrate neurogenesis. Nat Neurosci 2005; 8: 995-1001.
    • (2005) Nat Neurosci , vol.8 , pp. 995-1001
    • Sandberg, M.1    Kallstrom, M.2    Muhr, J.3
  • 16
    • 78149287968 scopus 로고    scopus 로고
    • Proteomic analysis of Sox2-associated proteins during early stages of mouse embryonic stem cell differentiation identifies Sox21 as a novel regulator of stem cell fate
    • Mallanna SK, Ormsbee BD, Iacovino M, et al. Proteomic analysis of Sox2-associated proteins during early stages of mouse embryonic stem cell differentiation identifies Sox21 as a novel regulator of stem cell fate. Stem Cells 2010; 28: 1715-27.
    • (2010) Stem Cells , vol.28 , pp. 1715-1727
    • Mallanna, S.K.1    Ormsbee, B.D.2    Iacovino, M.3
  • 17
    • 80055106066 scopus 로고    scopus 로고
    • Genetic and epigenetic modifications of Sox2 contribute to the invasive phenotype of malignant gliomas
    • Alonso MM, Diez-Valle R, Manterola L, et al. Genetic and epigenetic modifications of Sox2 contribute to the invasive phenotype of malignant gliomas. PLoS One 2011; 6: e26740.
    • (2011) PLoS One , vol.6
    • Alonso, M.M.1    Diez-Valle, R.2    Manterola, L.3
  • 18
    • 70350641014 scopus 로고    scopus 로고
    • SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas
    • Bass AJ, Watanabe H, Mermel CH, et al. SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas. Nat Genet 2009; 41: 1238-42.
    • (2009) Nat Genet , vol.41 , pp. 1238-1242
    • Bass, A.J.1    Watanabe, H.2    Mermel, C.H.3
  • 19
    • 42649112047 scopus 로고    scopus 로고
    • An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
    • Ben-Porath I, Thomson MW, Carey VJ, et al. An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nat Genet 2008; 40: 499-507.
    • (2008) Nat Genet , vol.40 , pp. 499-507
    • Ben-Porath, I.1    Thomson, M.W.2    Carey, V.J.3
  • 20
    • 77956028249 scopus 로고    scopus 로고
    • ChIP-seq and functional analysis of the SOX2 gene in colorectal cancers
    • Fang X, Yu W, Li L, et al. ChIP-seq and functional analysis of the SOX2 gene in colorectal cancers. OMICS 2010; 14: 369-84.
    • (2010) OMICS , vol.14 , pp. 369-384
    • Fang, X.1    Yu, W.2    Li, L.3
  • 21
    • 0034058559 scopus 로고    scopus 로고
    • Modulation of phenotype and induction of irregular vessels accompany high tumorigenic potential of clonal human glioma cells xenografted to nude-rat brain
    • Enblad P, Hesselager G, Bongcam-Rudloff E, et al. Modulation of phenotype and induction of irregular vessels accompany high tumorigenic potential of clonal human glioma cells xenografted to nude-rat brain. Int J Cancer 2000; 85: 819-28.
    • (2000) Int J Cancer , vol.85 , pp. 819-828
    • Enblad, P.1    Hesselager, G.2    Bongcam-Rudloff, E.3
  • 22
    • 80053311318 scopus 로고    scopus 로고
    • Glycosylation-related gene expression is linked to differentiation status in glioblastomas undifferentiated cells
    • Cheray M, Petit D, Forestier L, et al. Glycosylation-related gene expression is linked to differentiation status in glioblastomas undifferentiated cells. Cancer Lett 2011; 312: 24-32.
    • (2011) Cancer Lett , vol.312 , pp. 24-32
    • Cheray, M.1    Petit, D.2    Forestier, L.3
  • 23
    • 84879924426 scopus 로고    scopus 로고
    • Snail depletes the tumorigenic potential of glioblastoma
    • in press.
    • Savary K, Caglayan D, Caja L, et al. Snail depletes the tumorigenic potential of glioblastoma. Oncogene, in press.
    • Oncogene
    • Savary, K.1    Caglayan, D.2    Caja, L.3
  • 24
    • 66049085403 scopus 로고    scopus 로고
    • Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens
    • Pollard SM, Yoshikawa K, Clarke ID, et al. Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens. Cell Stem Cell 2009; 4: 568-80.
    • (2009) Cell Stem Cell , vol.4 , pp. 568-580
    • Pollard, S.M.1    Yoshikawa, K.2    Clarke, I.D.3
  • 25
    • 33845792555 scopus 로고    scopus 로고
    • CellProfiler: Image analysis software for identifying and quantifying cell phenotypes
    • Carpenter AE, Jones TR, Lamprecht MR, et al. CellProfiler: image analysis software for identifying and quantifying cell phenotypes. Genome Biol 2006; 7: R100.
    • (2006) Genome Biol , vol.7
    • Carpenter, A.E.1    Jones, T.R.2    Lamprecht, M.R.3
  • 27
    • 33845671339 scopus 로고    scopus 로고
    • Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma
    • Liu G, Yuan X, Zeng Z, et al. Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma. Mol Cancer 2006; 5: 67.
    • (2006) Mol Cancer , vol.5 , pp. 67
    • Liu, G.1    Yuan, X.2    Zeng, Z.3
  • 28
    • 33751252292 scopus 로고    scopus 로고
    • Direct observation of individual endogenous protein complexes in situ by proximity ligation
    • Soderberg O, Gullberg M, Jarvius M, et al. Direct observation of individual endogenous protein complexes in situ by proximity ligation. Nat Methods 2006; 3: 995-1000.
    • (2006) Nat Methods , vol.3 , pp. 995-1000
    • Soderberg, O.1    Gullberg, M.2    Jarvius, M.3
  • 29
    • 0032102860 scopus 로고    scopus 로고
    • Histone H3 phosphorylation and expression of cyclins A and B1 measured in individual cells during their progression through G2 and mitosis
    • Juan G, Traganos F, James WM, et al. Histone H3 phosphorylation and expression of cyclins A and B1 measured in individual cells during their progression through G2 and mitosis. Cytometry 1998; 32: 71-7.
    • (1998) Cytometry , vol.32 , pp. 71-77
    • Juan, G.1    Traganos, F.2    James, W.M.3
  • 30
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensive genomic characterization defines human glioblastoma genes and core pathways
    • The Cancer Genome Atlas Research Network.
    • The Cancer Genome Atlas Research Network. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature 2008; 455: 1061-8.
    • (2008) Nature , vol.455 , pp. 1061-1068
  • 31
    • 80755189318 scopus 로고    scopus 로고
    • Identification of a SOX2-dependent subset of tumor- and sphere-forming glioblastoma cells with a distinct tyrosine kinase inhibitor sensitivity profile
    • Hagerstrand D, He X, Bradic Lindh M, et al. Identification of a SOX2-dependent subset of tumor- and sphere-forming glioblastoma cells with a distinct tyrosine kinase inhibitor sensitivity profile. Neuro Oncol 2011; 13: 1178-91.
    • (2011) Neuro Oncol , vol.13 , pp. 1178-1191
    • Hagerstrand, D.1    He, X.2    Bradic Lindh, M.3
  • 32
    • 33646358694 scopus 로고    scopus 로고
    • Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
    • Lee J, Kotliarova S, Kotliarov Y, et al. Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines. Cancer Cell 2006; 9: 391-403.
    • (2006) Cancer Cell , vol.9 , pp. 391-403
    • Lee, J.1    Kotliarova, S.2    Kotliarov, Y.3
  • 33
    • 85058515750 scopus 로고    scopus 로고
    • Sox2: A glioma specific marker and a potential target for therapy
    • :(meeting abstract).
    • Eschbacher JM, Yeh R-F, Smirnov I, et al. Sox2: a glioma specific marker and a potential target for therapy. FASEB J 2008; 22: 706.18 (meeting abstract).
    • (2008) FASEB J , vol.22 , pp. 70618
    • Eschbacher, J.M.1    Yeh, R.-F.2    Smirnov, I.3
  • 34
    • 37549068145 scopus 로고    scopus 로고
    • Sox2 expression in brain tumors: A reflection of the neuroglial differentiation pathway
    • Phi JH, Park SH, Kim SK, et al. Sox2 expression in brain tumors: a reflection of the neuroglial differentiation pathway. Am J Surg Pathol 2008; 32: 103-12.
    • (2008) Am J Surg Pathol , vol.32 , pp. 103-112
    • Phi, J.H.1    Park, S.H.2    Kim, S.K.3
  • 35
    • 84879919952 scopus 로고    scopus 로고
    • The role of Sox transcription factors in brain tumorigenesis
    • ed. Rijeka: InTech
    • Ferletta M,. The role of Sox transcription factors in brain tumorigenesis. Molecular targets of CNS tumors. ed. Rijeka: InTech, 2011. 97-124.
    • (2011) Molecular Targets of CNS Tumors , pp. 97-124
    • Ferletta, M.1
  • 36
    • 59849125142 scopus 로고    scopus 로고
    • SOX2 silencing in glioblastoma tumor-initiating cells causes stop of proliferation and loss of tumorigenicity
    • Gangemi RM, Griffero F, Marubbi D, et al. SOX2 silencing in glioblastoma tumor-initiating cells causes stop of proliferation and loss of tumorigenicity. Stem Cells 2009; 27: 40-8.
    • (2009) Stem Cells , vol.27 , pp. 40-48
    • Gangemi, R.M.1    Griffero, F.2    Marubbi, D.3
  • 37
    • 77954386733 scopus 로고    scopus 로고
    • Sox2 is translationally activated by eukaryotic initiation factor 4E in human glioma-initiating cells
    • Ge Y, Zhou F, Chen H, et al. Sox2 is translationally activated by eukaryotic initiation factor 4E in human glioma-initiating cells. Biochem Biophys Res Commun 2010; 397: 711-7.
    • (2010) Biochem Biophys Res Commun , vol.397 , pp. 711-717
    • Ge, Y.1    Zhou, F.2    Chen, H.3
  • 38
    • 79951893576 scopus 로고    scopus 로고
    • Association of stem cell-related markers and survival in astrocytic gliomas
    • Wan F, Herold-Mende C, Campos B, et al. Association of stem cell-related markers and survival in astrocytic gliomas. Biomarkers 2011; 16: 136-43.
    • (2011) Biomarkers , vol.16 , pp. 136-143
    • Wan, F.1    Herold-Mende, C.2    Campos, B.3
  • 39
    • 79953649207 scopus 로고    scopus 로고
    • Activation of neural and pluripotent stem cell signatures correlates with increased malignancy in human glioma
    • Holmberg J, He X, Peredo I, et al. Activation of neural and pluripotent stem cell signatures correlates with increased malignancy in human glioma. PLoS One 2011; 6: e18454.
    • (2011) PLoS One , vol.6
    • Holmberg, J.1    He, X.2    Peredo, I.3
  • 40
    • 84866743307 scopus 로고    scopus 로고
    • Sox2 acts through Sox21 to regulate transcription in pluripotent and differentiated cells
    • Kuzmichev AN, Kim SK, D'Alessio AC, et al. Sox2 acts through Sox21 to regulate transcription in pluripotent and differentiated cells. Curr Biol 2012; 22: 1705-10.
    • (2012) Curr Biol , vol.22 , pp. 1705-1710
    • Kuzmichev, A.N.1    Kim, S.K.2    D'Alessio, A.C.3
  • 41
    • 79251591613 scopus 로고    scopus 로고
    • Rapid activation of the bivalent gene Sox21 requires displacement of multiple layers of gene-silencing machinery
    • Chakravarthy H, Ormsbee BD, Mallanna SK, et al. Rapid activation of the bivalent gene Sox21 requires displacement of multiple layers of gene-silencing machinery. FASEB J 2011; 25: 206-18.
    • (2011) FASEB J , vol.25 , pp. 206-218
    • Chakravarthy, H.1    Ormsbee, B.D.2    Mallanna, S.K.3
  • 42
    • 84865504366 scopus 로고    scopus 로고
    • Elevating SOX2 levels deleteriously affects the growth of medulloblastoma and glioblastoma cells
    • Cox JL, Wilder PJ, Desler M, et al. Elevating SOX2 levels deleteriously affects the growth of medulloblastoma and glioblastoma cells. PLoS One 2012; 7: e44087.
    • (2012) PLoS One , vol.7
    • Cox, J.L.1    Wilder, P.J.2    Desler, M.3
  • 43
    • 0034175998 scopus 로고    scopus 로고
    • Pairing SOX off: With partners in the regulation of embryonic development
    • Kamachi Y, Uchikawa M, Kondoh H,. Pairing SOX off: with partners in the regulation of embryonic development. Trends Genet 2000; 16: 182-7.
    • (2000) Trends Genet , vol.16 , pp. 182-187
    • Kamachi, Y.1    Uchikawa, M.2    Kondoh, H.3
  • 44
    • 2942594699 scopus 로고    scopus 로고
    • The Sox-2 regulatory regions display their activities in two distinct types of multipotent stem cells
    • Miyagi S, Saito T, Mizutani K, et al. The Sox-2 regulatory regions display their activities in two distinct types of multipotent stem cells. Mol Cell Biol 2004; 24: 4207-20.
    • (2004) Mol Cell Biol , vol.24 , pp. 4207-4220
    • Miyagi, S.1    Saito, T.2    Mizutani, K.3
  • 45
    • 0037100658 scopus 로고    scopus 로고
    • Identification of Sox-2 regulatory region which is under the control of Oct-3/4-Sox-2 complex
    • Tomioka M, Nishimoto M, Miyagi S, et al. Identification of Sox-2 regulatory region which is under the control of Oct-3/4-Sox-2 complex. Nucleic Acids Res 2002; 30: 3202-13.
    • (2002) Nucleic Acids Res , vol.30 , pp. 3202-3213
    • Tomioka, M.1    Nishimoto, M.2    Miyagi, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.