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Volumn 5, Issue 7, 2013, Pages 2457-2474

A population model of folate-mediated one-carbon metabolism

Author keywords

Mathematical model; Methionine cycle; Nhanes; Olate cycle; Population model

Indexed keywords

FOLIC ACID; HOMOCYSTEINE; METHIONINE; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE;

EID: 84879970580     PISSN: 20726643     EISSN: None     Source Type: Journal    
DOI: 10.3390/nu5072457     Document Type: Article
Times cited : (31)

References (36)
  • 3
    • 0032713838 scopus 로고    scopus 로고
    • Folic acid deficiency and cancer: Mechanisms of DNA instability
    • Duthie, S.J. Folic acid deficiency and cancer: Mechanisms of DNA instability. Br. Med. Bull. 1999, 55, 578-592.
    • (1999) Br. Med. Bull , vol.55 , pp. 578-592
    • Duthie, S.J.1
  • 4
    • 0033516320 scopus 로고    scopus 로고
    • Colorectal cancer: Molecules and populations
    • Potter, J.D. Colorectal cancer: Molecules and populations. J. Natl. Cancer Inst.1999,91, 916-932.
    • (1999) J. Natl. Cancer Inst , vol.91 , pp. 916-932
    • Potter, J.D.1
  • 5
    • 0043253373 scopus 로고    scopus 로고
    • Homocysteine In Human Reproduction
    • Carmel, R., Jacobsen, D.W., Eds.; Cambridge University Press: Cambridge, UK
    • Eskes, T.K.A.B. Homocysteine in Human Reproduction. In Homocysteine in Health and Disease; Carmel, R., Jacobsen, D.W., Eds.; Cambridge University Press: Cambridge, UK,2001; pp. 451-465.
    • In Homocysteine In Health and Disease , vol.2001 , pp. 451-465
    • Eskes, T.K.A.B.1
  • 7
    • 79961144280 scopus 로고    scopus 로고
    • Significance of differential expression of thymidylate synthase in normal and primary tumor tissues from patients with colorectal cancer
    • doi:10.1186/1756-8722-4-33
    • Liu, Y.; Xia, Q.; Jia, Y.; Guo, H.; Wei, B.; Hua, Y.; Yang, S. Significance of differential expression of thymidylate synthase in normal and primary tumor tissues from patients with colorectal cancer. J. Hematol. Oncol. 2011, 4, 33, doi:10.1186/1756-8722-4-33.
    • (2011) J. Hematol. Oncol , vol.4 , pp. 33
    • Liu, Y.1    Xia, Q.2    Jia, Y.3    Guo, H.4    Wei, B.5    Hua, Y.6    Yang, S.7
  • 8
    • 84879964469 scopus 로고    scopus 로고
    • MethyltransferasesElsevier: Kidlington
    • UK 2010
    • Lennard, L. Methyltransferases; Elsevier: Kidlington, UK, 2010. Nutrients 2013, 52473
    • (2013) Nutrients , pp. 52473
    • Lennard, L.1
  • 9
    • 15244348759 scopus 로고    scopus 로고
    • Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism
    • James, S.J.; Cutler, P.; Melnyk, S.; Jernigan, S.; Janak, L.; Gaylor, D.W.; Neubrander, J.A. Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism. Am. J. Clin. Nutr. 2004, 80, 1611-1617.
    • (2004) Am. J. Clin. Nutr , vol.80 , pp. 1611-1617
    • James, S.J.1    Cutler, P.2    Melnyk, S.3    Jernigan, S.4    Janak, L.5    Gaylor, D.W.6    Neubrander, J.A.7
  • 10
    • 1542376929 scopus 로고    scopus 로고
    • Glutathione metabolism and its implications for health
    • Wu, G.; Fang, Y.-Z.; Yang, S.; Lupton, J.R.; Turner, N.D. Glutathione metabolism and its implications for health. J. Nutr. 2004, 134, 489-492.
    • (2004) J. Nutr , vol.134 , pp. 489-492
    • Wu, G.1    Fang, Y.-Z.2    Yang, S.3    Lupton, J.R.4    Turner, N.D.5
  • 12
    • 0035099859 scopus 로고    scopus 로고
    • Measurement of plasma and intracellular S-adenosylmethionine and S-adenosylhomocysteine utilizing coulometric electrochemical detection: Alterations with plasma homocysteine and pyridoxal 5′-phosphate concentrations
    • Melnyk, S.; Pogribna, M.; Pogribny, I.; Yi, P.; James, S. Measurement of plasma and intracellular S-adenosylmethionine and S-adenosylhomocysteine utilizing coulometric electrochemical detection: Alterations with plasma homocysteine and pyridoxal 5′-phosphate concentrations. Clin. Chem. 2001, 47, 612.
    • (2001) Clin. Chem , vol.47 , pp. 612
    • Melnyk, S.1    Pogribna, M.2    Pogribny, I.3    Yi, P.4    James, S.5
  • 13
    • 84875836819 scopus 로고    scopus 로고
    • The relationship between intracellular and plasma levels of folate and metabolites in the methionine cycle: A model
    • Duncan, T.; Reed, M.; Nijhout, H. The relationship between intracellular and plasma levels of folate and metabolites in the methionine cycle: A model. Mol. Nutr. Food Res. 2013, 57, 626-638.
    • (2013) Mol. Nutr. Food Res , vol.57 , pp. 626-638
    • Duncan, T.1    Reed, M.2    Nijhout, H.3
  • 14
    • 33744761589 scopus 로고    scopus 로고
    • Long-range allosteric interactions between the folate and methionine cycles stabilize DNA methylation reaction rate
    • Nijhout, H.; Reed, M.; Anderson, D.; Mattingly, J.; James, J.; Ulrich, C. Long-range allosteric interactions between the folate and methionine cycles stabilize DNA methylation reaction rate. Epigenetics 2006, 1, 81-87.
    • (2006) Epigenetics , vol.1 , pp. 81-87
    • Nijhout, H.1    Reed, M.2    Anderson, D.3    Mattingly, J.4    James, J.5    Ulrich, C.6
  • 15
    • 11244333118 scopus 로고    scopus 로고
    • A mathematical model of the folate cycle--New insights into folate homeostasis
    • Nijhout, H.F.; Reed, M.C.; Budu, P.; Ulrich, C.M. A mathematical model of the folate cycle--New insights into folate homeostasis. J. Biol. Chem. 2004, 279, 55008-55016.
    • (2004) J. Biol. Chem , vol.279 , pp. 55008-55016
    • Nijhout, H.F.1    Reed, M.C.2    Budu, P.3    Ulrich, C.M.4
  • 16
    • 33749494516 scopus 로고    scopus 로고
    • A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism
    • Reed, M.C.; Nijhout, H.F.; Neuhouser, M.L.; Gregory, J.F.; Shane, B.; James, S.J.; Boynton, A.; Ulrich, C.M. A mathematical model gives insights into nutritional and genetic aspects of folate-mediated one-carbon metabolism. J. Nutr. 2006, 136, 2653-2661.
    • (2006) J. Nutr , vol.136 , pp. 2653-2661
    • Reed, M.C.1    Nijhout, H.F.2    Neuhouser, M.L.3    Gregory, J.F.4    Shane, B.5    James, S.J.6    Boynton, A.7    Ulrich, C.M.8
  • 20
    • 0024342063 scopus 로고
    • Plasma homocysteine, a risk factor for vascular disease: Plasma levels in health, disease, and drug therapy
    • Ueland, P.M.; Refsum, H. Plasma homocysteine, a risk factor for vascular disease: Plasma levels in health, disease, and drug therapy. J. Lab. Clin. Med. 1989, 114, 473-501.
    • (1989) J. Lab. Clin. Med , vol.114 , pp. 473-501
    • Ueland, P.M.1    Refsum, H.2
  • 23
    • 0026699645 scopus 로고
    • Modulation of rat liver S-adenosylmethionine synthetase activity by glutathione
    • Pajares, M.; Duran, C.; Corrales, F.; Pliego, M.; Mato, J. Modulation of rat liver S-adenosylmethionine synthetase activity by glutathione. J. Biol. Chem. 1992, 267, 17598-17605.
    • (1992) J. Biol. Chem , vol.267 , pp. 17598-17605
    • Pajares, M.1    Duran, C.2    Corrales, F.3    Pliego, M.4    Mato, J.5
  • 24
    • 0035071706 scopus 로고    scopus 로고
    • Case study: Folate bioavailability
    • Gregory, J.F. Case study: Folate bioavailability. J. Nutr. 2001, 131, 1376S-1382S.
    • (2001) J. Nutr , vol.131
    • Gregory, J.F.1
  • 25
    • 0042062309 scopus 로고    scopus 로고
    • Single oral doses of 13c forms of pteroylmonoglutamic acid and 5-formyltetrahydrofolic acid elicit differences in short-term kinetics of labelled and unlabelled folates in plasma: Potential problems in interpretation of folate bioavailability studies
    • Wright, A.J.A.; Finglas, P.M.; Dainty, J.R.; Hart, D.J.; Wolfe, C.A.; Southon, S.; Gregory, J.F. Single oral doses of 13c forms of pteroylmonoglutamic acid and 5-formyltetrahydrofolic acid elicit differences in short-term kinetics of labelled and unlabelled folates in plasma: Potential problems in interpretation of folate bioavailability studies. Br. J. Nutr. 2003, 90, 363-371.
    • (2003) Br. J. Nutr , vol.90 , pp. 363-371
    • Wright, A.J.A.1    Finglas, P.M.2    Dainty, J.R.3    Hart, D.J.4    Wolfe, C.A.5    Southon, S.6    Gregory, J.F.7
  • 26
    • 20444431586 scopus 로고    scopus 로고
    • Integrating the issues of bioavailability, intake and metabolism in the era of fortification
    • Gregory, J.F.; Quinlivan, E.P.; Davis, S.R. Integrating the issues of bioavailability, intake and metabolism in the era of fortification. Trends Food Sci. Technol. 2005, 16, 229-240.
    • (2005) Trends Food Sci. Technol , vol.16 , pp. 229-240
    • Gregory, J.F.1    Quinlivan, E.P.2    Davis, S.R.3
  • 28
    • 31544438802 scopus 로고    scopus 로고
    • Trends in serum folate, rbc folate, and circulating total homocysteine concentrations in the united states: Analysis of data from national health and nutrition examination surveys, 1988-1994, 1999-2000, and 2001-2002
    • Ganji, V.; Kafai, M. Trends in serum folate, rbc folate, and circulating total homocysteine concentrations in the united states: Analysis of data from national health and nutrition examination surveys, 1988-1994, 1999-2000, and 2001-2002. J. Nutr. 2006, 136, 153-158.
    • (2006) J. Nutr , vol.136 , pp. 153-158
    • Ganji, V.1    Kafai, M.2
  • 29
    • 0001504081 scopus 로고
    • Clincal Spectrum and Diagnosis of Folate Deficiency
    • Bailey, L.B., Ed.; Marcel Dekker, Inc.: New York, NY, USA
    • Lindenbaum, J.; Allen, R. Clincal Spectrum and Diagnosis of Folate Deficiency. In Folate in Health and Disease; Bailey, L.B., Ed.; Marcel Dekker, Inc.: New York, NY, USA, 1995, pp. 43-74.
    • (1995) Folate In Health and Disease , pp. 43-74
    • Lindenbaum, J.1    Allen, R.2
  • 30
    • 79959437034 scopus 로고    scopus 로고
    • Folate and vitamin B-12 biomarkers in nhanes: History of their measurement and use
    • Yetley, E.A.; Johnson, C.L. Folate and vitamin B-12 biomarkers in nhanes: History of their measurement and use. Am. J. Clin. Nutr. 2011, 94, doi: 10.3945/ajcn.111.013300.
    • (2011) Am. J. Clin. Nutr , pp. 94
    • Yetley, E.A.1    Johnson, C.L.2
  • 31
    • 0027382008 scopus 로고
    • Vitamin status and intake as primary determinants of homocysteinemia in an elderly population
    • Selhub, J.; Jacques, P.F.; Wilson, P.W.F.; Rush, D.; Rosenberg, I.H. Vitamin status and intake as primary determinants of homocysteinemia in an elderly population. J. Am. Med. Assoc. 1993, 270, 2693-2698.
    • (1993) Med. Assoc , vol.270 , pp. 2693-2698
    • Selhub, J.1    Jacques, P.F.2    Wilson, P.W.F.3    Rush, D.4    Rosenberg, I.H.5
  • 32
    • 33846821508 scopus 로고    scopus 로고
    • Williams, K.T.; Schalinske, K.L. New insights into the regulation of methyl group and homocysteine metabolism
    • Williams, K.T.; Schalinske, K.L. New insights into the regulation of methyl group and homocysteine metabolism. J. Nutr. 2007, 137, 311-314.
    • (2007) J. Nutr , vol.137 , pp. 311-314
  • 33
    • 0035172715 scopus 로고    scopus 로고
    • Intracellular S-adenosylhomocysteine concentrations predict global DNA hypomethylation in tissues of methyl-deficient cystathionine beta-synthase heterozygous mice
    • Caudill, M.A.; Wang, J.C.; Melnyk, S.; Pogribny, I.P.; Jernigan, S.; Collins, M.D.; Santos-Guzman, J.; Swendseid, M.E.; Cogger, E.A.; James, S.J. Intracellular S-adenosylhomocysteine concentrations predict global DNA hypomethylation in tissues of methyl-deficient cystathionine beta-synthase heterozygous mice. J. Nutr. 2001, 131, 2811-2818.
    • (2001) J. Nutr , vol.131 , pp. 2811-2818
    • Caudill, M.A.1    Wang, J.C.2    Melnyk, S.3    Pogribny, I.P.4    Jernigan, S.5    Collins, M.D.6    Santos-Guzman, J.7    Swendseid, M.E.8    Cogger, E.A.9    James, S.J.10
  • 35
    • 20244362795 scopus 로고    scopus 로고
    • A common insertion/deletion polymorphism of the thymidylate synthase (TYMS) gene is a determinant of red blood cell folate and homocysteine concentrations
    • Kealey, C.; Brown, K.; Woodside, J.; Young, I.; Murray, L.; Boreham, C.; McNulty, H.; Strain, J.J.; McPartlin, J.; Scott, J.; et al. A common insertion/deletion polymorphism of the thymidylate synthase (TYMS) gene is a determinant of red blood cell folate and homocysteine concentrations. Hum. Genet. 2005, 116, 347-353.
    • (2005) Hum. Genet , vol.116 , pp. 347-353
    • Kealey, C.1    Brown, K.2    Woodside, J.3    Young, I.4    Murray, L.5    Boreham, C.6    McNulty, H.7    Strain, J.J.8    McPartlin, J.9    Scott, J.10
  • 36
    • 0037369905 scopus 로고    scopus 로고
    • Effect of the methylenetetrahydrofolate reductase 677c→T mutation on the relations among folate intake and plasma folate and homocysteine concentrations in a general population sample
    • De Bree, A.; Verschuren, W.; Bjørke-Monsen, A.; van der Put, N.; Heil, S.; Trijbels, F.; Blom, H. Effect of the methylenetetrahydrofolate reductase 677c→T mutation on the relations among folate intake and plasma folate and homocysteine concentrations in a general population sample. Am. J. Clin. Nutr. 2003, 77, 687-693.
    • (2003) Am. J. Clin. Nutr , vol.77 , pp. 687-693
    • De Bree, A.1    Verschuren, W.2    Bjørke-Monsen, A.3    Van Der Put, N.4    Heil, S.5    Trijbels, F.6    Blom, H.7


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