Folate and vitamin B-12 biomarkers in NHANES: History of their measurement and use

American Journal of Clinical Nutrition

Volumn 94, Issue 1, 2011, Pages

  Yetley, Elizabeth A ^a   Johnson, Clifford L ^b  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL CENTER FOR HEALTH STATISTICS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 METHYLTETRAHYDROFOLIC ACID; BIOLOGICAL MARKER; CYANOCOBALAMIN; FOLIC ACID; HOMOCYSTEINE; METHYLMALONIC ACID;

ACCURACY; CONFERENCE PAPER; CYANOCOBALAMIN BLOOD LEVEL; FOLIC ACID BLOOD LEVEL; HEALTH CARE POLICY; HUMAN; VITAMIN BLOOD LEVEL;

BIAS (EPIDEMIOLOGY); BIOLOGICAL MARKERS; FOLIC ACID; HOMOCYSTEINE; HUMANS; METHYLMALONIC ACID; NUTRITION SURVEYS; PUBLIC POLICY; VITAMIN B 12;

EID: 79959437034     PISSN: 00029165     EISSN: 19383207     Source Type: Journal    
DOI: 10.3945/ajcn.111.013300     Document Type: Conference Paper

References (71)

1. Yetley E, Johnson C. Nutritional applications of the Health and Nutrition Examination Surveys (HANES). Annu Rev Nutr 1987;7:441-63.
2. Centers for Disease Control and Prevention. About the National Health and Nutrition Examination Survey. Available from: http://www.cdc.gov/nchs/nhanes. htm (cited 8 January 2011).
3. Wright JD, Borrud LG, McDowell MA, Wang C-Y, Radimer K, Johnson CL. Nutrition assessment in the National Health and Nutrition Examination Survey 1999-2002. J Am Diet Assoc 2007;107:822-9.
4. Yetley EA, Pfeiffer CM, Phinney KW, et al. Biomarkers of folate status in NHANES: a roundtable summary. Am J Clin Nutr 2011;94(suppl):nn.
5. Yetley EA, Pfeiffer CM, Phinney KW, et al. Biomarkers of vitamin B-12 status in NHANES: a roundtable summary. Am J Clin Nutr 2011;94(suppl):nn-nn.
6. Yetley EA, Coates PM, Johnson CL. Overview of a roundtable on NHANES monitoring of biomarkers of folate and vitamin B-12 status: measurement procedure issues. Am J Clin Nutr 2011;94(suppl):nn-nn.
7. 12 status and for monitoring the efficacy of intervention strategies. Food Nutr Bull 2008;29:S52-63.
8. Shane B. Folate status assessment history: implications for measurement of biomarkers in NHANES. Am J Clin Nutr 2011;94(suppl):nn-nn.
9. Carmel R. Biomarkers of cobalamin (vitamin B-12) status in the epidemiologic setting: a critical overview of context, applications, and performance characteristics of cobalamin, methylmalonic acid, and holotranscobalamin II. Am J Clin Nutr 2011;94(suppl):nn-nn.
10. Bailey RL, Mills JL, Yetley EA, et al. Unmetabolized serum folic acid and its relation to folic acid intake from diet and supplements in a nationally representative sample of adults aged ≥60 y in the United States. Am J Clin Nutr 2010;92:383-9.
11. Kalmbach RD, Choumenkovitch SF, Troen AM, D'Agostino R, Jacques PF, Selhub J. Circulating folic acid in plasma: relation to folic acid fortification. Am J Clin Nutr 2008;88:763-8.
12. Morris MS, Jacques PF, Rosenberg IH, Selhub J. Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors. Am J Clin Nutr 2010;91:1733-44.
13. Sweeney MR, Staines A, Daly L, et al. Persistent circulating unmetabolised folic acid in a setting of liberal voluntary folic acid fortification. Implications for further mandatory fortification? BMC Public Health 2009;9:295-301.
14. Mason JB. Folate, cancer risk, and the Greek god, Proteus: a tale of two chameleons. Nutr Rev 2009;67:206-12.
15. Senti FR, Pilch SM. Analysis of folate data from the second National Health and Nutrition Examination Survey (NHANES II). J Nutr 1985;115:1398-402. (Pubitemid 16234415)
16. Yetley EA, Rader JI. Modeling the level of fortification and postfortification assessments: U.S. experience. Nutr Rev 2004;62:S50-9.
17. Morris MS, Jacques PF, Rosenberg IH, Selhub J. Elevated serum methylmalonic acid concentrations are common among elderly Americans. J Nutr 2002;132:2799-803. (Pubitemid 35013273)
18. Selhub J, Jacques PF, Rosenberg IH, et al. Serum total homocysteine concentrations in the third National Health and Nutrition Examination Survey (1991-1994): population reference ranges and contribution of vitamin status to high serum concentrations. Ann Intern Med 1999;131:331-9.
19. Life Sciences Research Office. Suggested measures of nutritional status and health conditions for the third National Health and Nutrition Examination Survey. Bethesda, MD: Federation of American Societies for Experimental Biology, 1985.
20. Raiten DJ, Fisher KD. Assessment of folate methodology used in the third National Health and Nutrition Examination Survey (NHANES III, 1988-1994). J Nutr 1995;125:1371S-98S.
21. Pfeiffer CM, Caudill SP, Gunter EW, Osterloh J, Sampson EJ. Biochemical indicators of B vitamin status in the US population after folic acid fortification: results from the National Health and Nutrition Examination Survey 1999-2000. Am J Clin Nutr 2005;82:442-50.
22. Pfeiffer CM, Johnson CL, Jain RB, et al. Trends in blood folate and vitamin B-12 concentrations in the United States, 1988-2004. Am J Clin Nutr 2007;86:718-27.
23. Pfeiffer CM, Osterloh JD, Kennedy-Stephenson J, et al. Trends in circulating concentrations of total homocysteine among US adolescents and adults: findings from the 1991-1994 and 1999-2004 National Health and Nutrition Examination Surveys. Clin Chem 2008;54:801-13.
24. Smith AD. Folic acid fortification: the good, the bad, and the puzzle of vitamin B-12. Am J Clin Nutr 2007;85:3-5. (Pubitemid 46067608)
25. Kuczmarski RJ, Ogden CL, Guo SS, et al. 2000 CDC growth charts for the United States: Methods and development. National Center for Health Statistics. Vital Health Stat 11 2002;246:1-190.
26. McDowell MA, Fryar CD, Ogden CL. Anthropometric reference data for children and adults: United States, 1988-1994. National Center for Health Statistics. Vital Health Stat 11 2009;249:1-68.
27. Centers for Disease Control and Prevention. Water-soluble vitamins & related biochemical compounds. In: National report on biochemical indicators of diet and nutrition in the U.S. population 1999-2002. Available from: http://www.cdc.gov/nutritionreport/summary.html (cited 8 January 2011).
28. 12: United States, 1988-94. Vital Health Stat 11 1998;243:1-78.
29. Ganji V, Kafai MR. Population reference values for plasma total homocysteine concentrations in US adults after the fortification of cereals with folic acid. Am J Clin Nutr 2006;84:989-94. (Pubitemid 44730366)
30. 12 status. Food Nutr Bull 2008;29:S67-73.
31. Bazzano LA, He J, Ogden LG, et al. Dietary intake of folate and risk of stroke in US men and women. NHANES I epidemiologic follow-up study. Stroke 2002;33:1183-9.
32. Ford ES, Giles WH. Serum vitamins, carotenoids, and angina pectoris: findings from the National Health and Nutrition Examination Survey III. Ann Epidemiol 2000;10:106-16. (Pubitemid 30089020)
33. Giles WH, Croft JB, Greenlund KJ, Ford ES, Kittner SJ. Total homocyst(e)ine concentration and the likelihood of nonfatal stroke: results from the third National Health and Nutrition Examination Survey, 1988-1994. Stroke 1998;29:2473-7.
34. Giles WH, Croft JB, Greenlund KJ, Ford ES, Kittner SJ. Association between total homocyst(e)ine and the likelihood for a history of acute myocardial infarction by race and ethnicity: results from the third National Health and Nutrition Examination Survey. Am Heart J 2000;139:446-53. (Pubitemid 30149194)
35. Kuo HK, Yen CJ, Bean JF. Levels of homocysteine are inversely associated with cardiovascular fitness in women, but not in men: data from the National Health and Nutrition Examination Survey 1999-2002. J Intern Med 2005;258:328-35.
36. Loria CM, Ingram DD, Feldman JJ, Wright JD, Madans JH. Serum folate and cardiovascular disease mortality among US men and women. Arch Intern Med 2000;160:3258-62.
37. Lane JS, Magno CP, Lane KT, Chan T, Hoyt DB, Greenfield S. Nutrition impacts the prevalence of peripheral arterial disease in the United States. J Vasc Surg 2008;48:897-904.
38. Morris MS, Jacques PF, Rosenberg IH, et al. Serum total homocysteine concentration is related to self-reported heart attack or stroke history among men and women in the NHANES III. J Nutr 2000;130:3073-6. (Pubitemid 32005343)
39. Kant AK. Weight-loss attempts and reporting of foods and nutrients, and biomarkers in a national cohort. Int J Obes Relat Metab Disord 2002;26:1194-204.
40. Kimmons JE, Blanck HM, Tohill BC, Zhang J, Khan LK. Associations between body mass index and the prevalence of low micronutrient levels among US adults. Med Gen Med 2006;8:59.
41. Krieg EF Jr, Butler MA. Blood lead, serum homocysteine, and neurobehavioral test performance in the third National Health and Nutrition Examination Survey. Neurotoxicology 2009;30:281-9.
42. Kim DB, Oh YS, Yoo KD, et al. Passive smoking in never-smokers is associated with increased plasma homocysteine levels. Int Heart J 2010;51:183-7.
43. Mannino DM, Mulinare J, Ford ES, Schwartz J. Tobacco smoke exposure and decreased serum and red blood cell folate levels: data from the third National Health and Nutrition Examination Survey. Nicotine Tob Res 2003;5:357-62. (Pubitemid 36764031)
44. Selhub J, Morris MS, Jacques PF, Rosenberg IH. Folate - vitamin B-12 interaction in relation to cognitive impairment, anemia, and biochemical indicators of vitamin B-12 deficiency. Am J Clin Nutr 2009;89(suppl):702S-6S.
45. Morris MS, Jacques PF, Rosenberg IH, Selhub J. Folate and vitamin B-12 status in relation to anemia, macrocytosis, and cognitive impairment in older Americans in the age of folic acid fortification. Am J Clin Nutr 2007;85:193-200. (Pubitemid 46067634)
46. Morris MS, Jacques PF, Rosenberg IH, Selhub J. Hyperhomocysteinemia associated with poor recall in the third National Health and Nutrition Examination Survey. Am J Clin Nutr 2001;73:927-33. (Pubitemid 32405990)
47. Morris MS, Bostom AG, Jacques PF, Selhub J, Rosenberg IH. Hyperhomocysteinemia and hypercholesterolemia associated with hypothyroidism in the third US National Health and Nutrition Examination Survey. Atherosclerosis 2001;155:195-200. (Pubitemid 32167140)
48. Yu Y-H, Kuo H-K, Lai Y-L. The association between serum folate levels and periodontal disease in older adults: data from the National Health and Nutrition Examination Survey 2001/02. J Am Geriatr Soc 2007;55:108-13.
49. Nowjack-Raymer RE, Sheiham A. Numbers of natural teeth, diet, and nutritional status in US adults. J Dent Res 2007;86:1171-5.
50. Su LJ, Arab L. Nutritional status of folate and colon cancer risk: evidence from NHANES I Epidemiologic Follow-up Study. Ann Epidemiol 2001;11:65-72. (Pubitemid 32054790)
51. Yang Q-H, Botto LD, Gallagher M, et al. Prevalence and effects of gene-gene and gene-nutrient interactions on serum folate and serum total homocysteine concentrations in the United States: findings from the third National Health and Nutrition Examination Survey DNA bank. Am J Clin Nutr 2008;88:232-46. (Pubitemid 351988705)
52. Kant AK, Graubard BI. Ethnicity is an independent correlate of biomarkers of micronutrient intake and status in American adults. J Nutr 2007;137:2456-63. (Pubitemid 350058716)
53. Yang Q, Cogswell ME, Hamner HC, et al. Folic acid source, usual intake, and folate and vitamin B-12 status in US adults: National Health and Nutrition Examination Survey (NHANES) 2003-2006. Am J Clin Nutr 2010;91:64-72.
54. McKeown NM, Day NE, Welch AA, et al. Use of biological markers to validate self-reported dietary intake in a random sample of the European Prospective Investigation into Cancer United Kingdom Norfolk cohort. Am J Clin Nutr 2001;74:188-96.
55. Clarke R, Halsey J, Lewington S, et al; B-Vitamin Treatment Trialists' Collaboration. Effects of lowering homocysteine levels with B vitamins on cardiovascular disease, cancer, and cause-specific mortality: meta-analysis of 8 randomized trials involving 37 485 individuals. Arch Intern Med 2010;170:1622-31.
56. Satterfield MB, Sniegoski LT, Sharpless KE, et al. Development of a new standard reference material: SRM 1955 (homocysteine and folate in human serum). Anal Bioanal Chem 2006;385:612-22.
57. Vesper HW, Thienpont LM. Traceability in laboratory medicine. Clin Chem 2009;55:1067-75.
58. Yetley EA, Pfeiffer CM, Schleicher RL, et al. NHANES monitoring of serum 25-hydroxyvitamin D: a roundtable summary. J Nutr 2010;140:2030S-45S.
59. Bock JL, Eckfeldt JH. Advances in standardization of laboratory measurement procedures: implications for measuring biomarkers of folate and vitamin B-12 status in the National Health and Nutrition Examination Survey (NHANES). Am J Clin Nutr 2011;94(suppl):nn-nn.
60. Looker AC, Pfeiffer CM, Lacher DA, Schleicher RL, Picciano MF, Yetley EA. Serum 25-hydroxyvitamin D status of the US population: 1988-1994 compared with 2000-2004. Am J Clin Nutr 2008;88:1519-27.
61. Pfeiffer CM, Caudill SP, Gunter EW, et al. Analysis of factors influencing the comparison of homocysteine values between the third National Health and Nutrition Examination Survey (NHANES) and NHANES 1999+. J Nutr 2000;130:2850-4.
62. Centers for Disease Control and Prevention. NCHS analytic note - serum folate regression equations to compare 2007-2008 and 1999-2006 data and red blood cell folate comparison of 2007-2008 and 1999-2006 data. Available from: http://www.cdc.gov/nchs/nhanes/nhanes2007-2008/FOLATE-E.htm (in press).
63. Selvin E, Manzi J, Stevens LA, et al. Calibration of serum creatinine in the National Health and Nutrition Examination Surveys (NHANES) 1988-1994, 1999-2004. Am J Kidney Dis 2007;50:918-26.
64. Joint Committee on Traceability in Laboratory Medicine. Bureau International des Poids et Mesures, Sèvres Cedex, Frances. Available from: http://www.bipm.org/jctlm/ (cited 4 December 2010).
65. National Institute of Standards and Technology. Certificate of analysis, standard reference material 1955. Homocysteine and folate in frozen human serum. April 2008. Available from: https://www-s.nist.gov/srmors/certificates/1955. pdf?CFID=1126897&CFTOKEN=ad62a5219ffb884e- 41496E79-A2D7-BED2- 991CE742A98A0716&jsessionid=f030a960d9d22f92f6db3a34674d5a634a2a (cited 14 January 2011).
66. Statistics Canada. Canadian Health Measures Survey: cycle 1 data tables, 2007 to 2009. Available from: http://www.statcan.gc.ca/pub/82-623-x/82-623- x2010002-eng.htm (cited 8 January 2011).
67. Institute of Medicine. Dietary reference intakes for calcium and vitamin D. Washington, DC: The National Academies Press, 2011.
68. Durazo-Arvizu RA, Dawson-Hughes B, Sempos CT, et al. Three-phase model harmonizes estimates of the maximal suppression of parathyroid hormone by 25-hydroxyvitamin D in persons 65 years of age and older. J Nutr 2010;140:595-9.
69. Looker AC, Sempos CT, Liu K, Johnson CL, Gunter EW. Withinperson variance in biochemical indicators of iron status: effects on prevalence estimates. Am J Clin Nutr 1990;52:541-7. (Pubitemid 20260632)
70. Lacher DA, Hughes JP, Carroll MD. Estimate of biological variation of laboratory analytes based on the third National Health and Nutrition Examination Survey. Clin Chem 2005;51:450-2. (Pubitemid 40175818)
71. Lacher DA, Hughes JP, Carroll MD. Biological variation of laboratory analytes based on the 1999-2002 National Health and Nutrition Examination Survey. National Health Statistics Reports; no 21. Hyattsville, MD: National Center for Health Statistics. 2010. Available from: http://www.cdc.gov/nchs/ data/nhsr/nhsr021.pdf (cited 8 January 2011).