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Volumn 38, Issue 15, 2013, Pages 1253-1259

Minocycline treatment inhibits lipid peroxidation, preserves spinal cord ultrastructure, and improves functional outcome after traumatic spinal cord injury in the rat

Author keywords

Apoptosis; behavioral assessment; lipid peroxidation; minocycline; neuroprotection; traumatic spinal cord injury

Indexed keywords

BIOTIN; DEOXYURIDINE; DNA NUCLEOTIDYLEXOTRANSFERASE; GLUTATHIONE; MALONALDEHYDE; MINOCYCLINE;

EID: 84879962972     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/BRS.0b013e3182895587     Document Type: Article
Times cited : (48)

References (19)
  • 1
    • 8844254741 scopus 로고    scopus 로고
    • The promise of minocycline in neurology
    • Yong VW, Wells J, Giuliani F, et al. The promise of minocycline in neurology. Lancet Neurol 2004; 3: 744-51.
    • (2004) Lancet Neurol , vol.3 , pp. 744-751
    • Yong, V.W.1    Wells, J.2    Giuliani, F.3
  • 3
    • 0033500846 scopus 로고    scopus 로고
    • Effect of mexiletine on lipid peroxidation and early ultrastructural findings in experimental spinal cord injury
    • Kaptanoglu E, Caner HH, Surucu HS, et al. Effect of mexiletine on lipid peroxidation and early ultrastructural findings in experimental spinal cord injury. J Neurosurg 1999; 91: 200-4.
    • (1999) J Neurosurg , vol.91 , pp. 200-204
    • Kaptanoglu, E.1    Caner, H.H.2    Surucu, H.S.3
  • 4
    • 12144290904 scopus 로고    scopus 로고
    • Minocycline inhibits contu-sion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury
    • Teng YD, Choi H, Onario RC, et al. Minocycline inhibits contu-sion-triggered mitochondrial cytochrome c release and mitigates functional deficits after spinal cord injury. Proc Natl Acad Sci USA 2004; 101: 3071-6.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 3071-3076
    • Teng, Y.D.1    Choi, H.2    Onario, R.C.3
  • 5
    • 24944474880 scopus 로고    scopus 로고
    • Mexiletine treatment-induced inhibition of caspase-3 activation and improvement of behavioral recovery after spinal cord injury
    • Kaptanoglu E, Caner H, Solaroglu I, et al. Mexiletine treatment-induced inhibition of caspase-3 activation and improvement of behavioral recovery after spinal cord injury. J Neurosurg Spine 2005; 3: 53-6.
    • (2005) J Neurosurg Spine , vol.3 , pp. 53-56
    • Kaptanoglu, E.1    Caner, H.2    Solaroglu, I.3
  • 6
    • 0017872475 scopus 로고
    • Microsomal lipid peroxidation
    • Buege JA, Aust SD. Microsomal lipid peroxidation. Methods Enzymol 1978; 52: 302-10.
    • (1978) Methods Enzymol , vol.52 , pp. 302-310
    • Buege, J.A.1    Aust, S.D.2
  • 7
    • 3042934967 scopus 로고
    • Tissue sulfhydryl groups
    • Ellman GL. Tissue sulfhydryl groups. Arch Biochem Biophys 1959; 82: 70-7.
    • (1959) Arch Biochem Biophys , vol.82 , pp. 70-77
    • Ellman, G.L.1
  • 8
    • 0036291604 scopus 로고    scopus 로고
    • Ultrastructural scor-ing of graded acute spinal cord injury in the rat
    • Kaptanoglu E, Palaoglu S, Surucu HS, et al. Ultrastructural scor-ing of graded acute spinal cord injury in the rat J Neurosurg 2002; 97: 49-56.
    • (2002) J Neurosurg , vol.97 , pp. 49-56
    • Kaptanoglu, E.1    Palaoglu, S.2    Surucu, H.S.3
  • 9
    • 1642269715 scopus 로고    scopus 로고
    • Erythropoietin exerts neuroprotection after acute spinal cord injury in rats: Effect on lipid peroxidation and early ultrastructural findings
    • Kaptanoglu E, Solaroglu I, Okutan O, et al. Erythropoietin exerts neuroprotection after acute spinal cord injury in rats: effect on lipid peroxidation and early ultrastructural findings. Neurosurg Rev 2004; 27: 113-20.
    • (2004) Neurosurg Rev , vol.27 , pp. 113-120
    • Kaptanoglu, E.1    Solaroglu, I.2    Okutan, O.3
  • 10
    • 0028919411 scopus 로고
    • A sensitive and reliable locomotor rating scale for open field testing in rats
    • Basso DM, Beattie MS, Bresnahan JC. A sensitive and reliable locomotor rating scale for open field testing in rats. J Neurotrauma 1995; 12: 1-21.
    • (1995) J Neurotrauma , vol.12 , pp. 1-21
    • Basso, D.M.1    Beattie, M.S.2    Bresnahan, J.C.3
  • 11
    • 0037481943 scopus 로고    scopus 로고
    • Neuroprotection by minocycline facilitates significant recovery from spinal cord injury in mice
    • Wells JE, Hurlbert RJ, Fehlings MG, et al. Neuroprotection by minocycline facilitates significant recovery from spinal cord injury in mice. Brain 2003; 126: 1628-37.
    • (2003) Brain , vol.126 , pp. 1628-1637
    • Wells, J.E.1    Hurlbert, R.J.2    Fehlings, M.G.3
  • 12
    • 0032442475 scopus 로고    scopus 로고
    • Tetracyclines inhibit microglial activation and are neuroprotective in global brain isch-emia
    • Yrjanheikki J, Keinanen R, Pellikka M, et al. Tetracyclines inhibit microglial activation and are neuroprotective in global brain isch-emia. Proc Natl Acad Sci USA 1998; 95: 15769-74.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 15769-15774
    • Yrjanheikki, J.1    Keinanen, R.2    Pellikka, M.3
  • 13
    • 0142025464 scopus 로고    scopus 로고
    • Minocycline reduces cell death and improves functional recovery after traumatic spinal cord injury in the rat
    • Lee SM, Yune TY, Kim SJ, et al. Minocycline reduces cell death and improves functional recovery after traumatic spinal cord injury in the rat. J Neurotrauma 2003; 20: 1017-27.
    • (2003) J Neurotrauma , vol.20 , pp. 1017-1027
    • Lee, S.M.1    Yune, T.Y.2    Kim, S.J.3
  • 14
    • 55649088905 scopus 로고    scopus 로고
    • A re-assessment of mino-cycline as a neuroprotective agent in a rat spinal cord contusion model
    • Pinzon A, Marcillo A, Quintana A, et al. A re-assessment of mino-cycline as a neuroprotective agent in a rat spinal cord contusion model. Brain Res 2008; 1243: 146-51.
    • (2008) Brain Res , vol.1243 , pp. 146-151
    • Pinzon, A.1    Marcillo, A.2    Quintana, A.3
  • 15
    • 84870927178 scopus 로고    scopus 로고
    • What is behind the non-antibiotic properties of minocycline?
    • Garrido-Mesa N, Zarzuelo A, Gálvez J. What is behind the non-antibiotic properties of minocycline? Pharmacol Res 2013; 67: 18-30.
    • (2013) Pharmacol Res , vol.67 , pp. 18-30
    • Garrido-Mesa, N.1    Zarzuelo, A.2    Gálvez, J.3
  • 16
    • 1542722933 scopus 로고    scopus 로고
    • Optimal delivery of minocycline to the brain: Implication for human studies of acute neuroprotection
    • Fagan SC, Edwards DJ, Borlongan CV, et al. Optimal delivery of minocycline to the brain: implication for human studies of acute neuroprotection. Exp Neurol 2004; 186: 248-51.
    • (2004) Exp Neurol , vol.186 , pp. 248-251
    • Fagan, S.C.1    Edwards, D.J.2    Borlongan, C.V.3
  • 17
    • 0038359549 scopus 로고    scopus 로고
    • Liquid chromatographic determination of minocycline in brain-to-plasma distribution studies in the rat
    • Colovic M, Caccia S. Liquid chromatographic determination of minocycline in brain-to-plasma distribution studies in the rat J Chromatogr B Analyt Technol Biomed Life Sci 2003; 791: 337-43.
    • (2003) J Chromatogr B Analyt Technol Biomed Life Sci , vol.791 , pp. 337-343
    • Colovic, M.1    Caccia, S.2
  • 18
    • 2642545055 scopus 로고    scopus 로고
    • Low dose intravenous minocycline is neuroprotective after middle cerebral artery occlusion-reperfusion in rats
    • Xu L, Fagan SC, Waller JL, et al. Low dose intravenous minocycline is neuroprotective after middle cerebral artery occlusion-reperfusion in rats. BMC Neurol 2004; 4: 7.
    • (2004) BMC Neurol , vol.4 , pp. 7
    • Xu, L.1    Fagan, S.C.2    Waller, J.L.3
  • 19
    • 18144393838 scopus 로고    scopus 로고
    • Minocycline inhibits oxidative stres and decreases in vitro and in vivo ischemic neuronal damage
    • Morimoto N, Shimazawa M, Yamashima T, et al. Minocycline inhibits oxidative stres and decreases in vitro and in vivo ischemic neuronal damage. Brain Res 2005; 1044: 8-15.
    • (2005) Brain Res , vol.1044 , pp. 8-15
    • Morimoto, N.1    Shimazawa, M.2    Yamashima, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.