Sex hormone binding globulin and sex steroids among premenopausal women in the diabetes prevention program

Journal of Clinical Endocrinology and Metabolism

Volumn 98, Issue 7, 2013, Pages 3049-3057

  Kim, Catherine ^a   Pi Sunyer, Xavier ^b   Barrett Connor, Elizabeth ^c   Stentz, Frankie B ^d   Murphy, Mary Beth ^d   Kong, Shengchun ^a   Nan, Bin ^a   Kitabchi, Abbas E ^d  

^a UNIVERSITY OF MICHIGAN   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROSTERONE; ESTRADIOL; METFORMIN; PLACEBO; PRASTERONE; SEX HORMONE; SEX HORMONE BINDING GLOBULIN; TESTOSTERONE;

ADULT; ARTICLE; CONTROLLED STUDY; DIABETES CONTROL; DIABETES MELLITUS; FEMALE; HEALTH PROGRAM; HORMONE ACTION; HUMAN; LIFESTYLE MODIFICATION; OUTCOME ASSESSMENT; POSTMENOPAUSE; PRIORITY JOURNAL; RACE DIFFERENCE; RANDOMIZED CONTROLLED TRIAL; SEX HORMONE DETERMINATION; WAIST CIRCUMFERENCE; WEIGHT REDUCTION;

ADULT; AFRICAN AMERICANS; BODY MASS INDEX; COMBINED MODALITY THERAPY; DIABETES MELLITUS; DIET, REDUCING; ESTRADIOL; EUROPEAN CONTINENTAL ANCESTRY GROUP; EXERCISE; FEMALE; FOLLOW-UP STUDIES; GLUCOSE INTOLERANCE; HISPANIC AMERICANS; HUMANS; HYPOGLYCEMIC AGENTS; METFORMIN; MIDDLE AGED; OVERWEIGHT; PREMENOPAUSE; SEX HORMONE-BINDING GLOBULIN; TESTOSTERONE CONGENERS; UNITED STATES;

EID: 84879943923     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2013-1341     Document Type: Article

References (38)

1. Eliassen AH, Missmer SA, Tworoger SS, et al. Endogenous steroid hormone concentrations and risk of breast cancer among premenopausal women. J Natl Cancer Inst. 2006;98:1406-1415. (Pubitemid 44530717)
2. Ding EL, Song Y, Malik VS, Liu S. Sex differences of endogenous sex hormones and risk of type 2 diabetes: a systematic review and metaanalysis. JAMA. 2006;295:1288-1299.
3. Endogenous Hormones and Breast Cancer Collaborative Group, Key TJ, Appleby PN, Reeves GK, et al. Circulating sex hormones and breast cancer risk factors in postmenopausal women: reanalysis of 13 studies. Br J Cancer. 2011;105:709-722.
4. Knowler WC, Barrett-Connor E, Fowler SE, et al, and the Diabetes Prevention Program Research Group. Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. N Engl J Med. 2002;346:393-403. (Pubitemid 34437694)
5. Moran L, Hutchinson S, Norman R, Teede H. Lifestyle changes in women with polycystic ovary syndrome. Cochrane Database Syst Rev. 2011;CD007506.
6. Williams NI, Reed JL, Leidy HJ, Legro RS, De Souza MJ. Estrogen and progesterone exposure is reduced in response to energy deficiency in women aged 25-40 years. Hum Reprod. 2010;25:2328-2339.
7. Ehrmann D. Polycystic ovary syndrome. N Engl J Med. 2005;352: 1223-1236.
8. Elkind-Hirsch K, Marrioneaux O, Bhushan M, Vernor D, Bhushan R. Comparison of single and combined treatment with exenatide and metformin on menstrual cyclicity in overweight women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2008;93:2670-2678. (Pubitemid 352008535)
9. Gambineri A, Patton L, Vaccina A, et al. Treatment with flutamide, metformin, and their combination added to a hypocaloric diet in overweight-obese women with polycystic ovary syndrome: a randomized, 12-month, placebo-controlled study. J Clin Endocrinol Metab. 2006;91:3970-3980. (Pubitemid 44536872)
10. Pasquali R, Gambineri A, Biscotti D, et al. Effect of long-term treatment with metformin added to hypocaloric diet on body composition, fat distribution, and androgen and insulin levels in abdominally obese women with and without the polycystic ovary syndrome. J Clin Endocrinol Metab. 2000;85:2767-2774. (Pubitemid 32269149)
11. Marsh EE, Shaw ND, Klingman KM, et al. Estrogen levels are higher across the menstrual cycle in African-American women compared with Caucasian women. J Clin Endocrinol Metab. 2011;96:3199-3206.
12. Randolph JF Jr, Sowers M, Gold EB, et al. Reproductive hormones in the early menopausal transition: relationship to ethnicity, body size, and menopausal status. J Clin Endocrinol Metab. 2003;88: 1516-1522. (Pubitemid 36623363)
13. Randolph JF Jr, Sowers M, Bondarenko IV, Harlow SD, Luborsky JL, Little RJ. Change in estradiol and follicle-stimulating hormone across the early menopausal transition: effects of ethnicity and age. J Clin Endocrinol Metab. 2004;89:1555-1561. (Pubitemid 38507902)
14. Wildman R, Wang D, Fernandez I, et al. Associations of testosterone and sex hormone binding globulin with adipose tissue hormones in midlife women. Obesity (Silver Spring). In Press.
15. Kitabchi AE, Temprosa M, Knowler WC, et al The Diabetes Prevention Program Research Group. Role of insulin secretion and sensitivity in the evolution of type 2 diabetes in the Diabetes Prevention Program: effects of lifestyle intervention and metformin. Diabetes. 2005;54:2404-2414. (Pubitemid 41134269)
16. Stentz FB, Umpierrez GE, Cuervo R, Kitabchi AE. Proinflammatory cytokines, markers of cardiovascular risks, oxidative stress, and lipid peroxidation in patients with hyperglycemic crises. Diabetes. 2004;53:2079-2086. (Pubitemid 38970758)
17. Liedtke S, Schmidt M, Vrieling A, et al. Postmenopausal sex hormones in relation to body fat distribution. Obesity (Silver Spring). 2012;20:1088-1095.
18. Friedenreich CM, Woolcott CG, McTiernan A, et al. Alberta physical activity and breast cancer prevention trial: sex hormone changes in a year-long exercise intervention among postmenopausal women. J Clin Oncol. 2010;28:1458-1466.
19. McTiernan A, Tworoger S, Ulrich C, et al. Effect of exercise on serum estrogens in postmenopausal women: a 12-month randomized clinical trial. Canc Res. 2004;64:2923-2928. (Pubitemid 38500634)
20. Berrino F, Bellati C, Secreto G, et al. Reducing bioavailable sex hormones through a comprehensive change in diet: the diet and androgens (DIANA) randomized trial. Cancer Epidemiol Biomarkers Prev. 2001;10:25-33. (Pubitemid 32106041)
21. Kim C, Nan B, Laughlin GA, et al. Endogenous sex hormone changes in postmenopausal women in the Diabetes Prevention Program. J Clin Endocrinol Metab. 2012;97:2853-2861.
22. Peter A, Kantartzis K, Machann J, et al. Relationships of circulating sex hormone-binding globulin with metabolic traits in humans. Diabetes. 2010;59:3167-3173.
23. Kumagai S, Shono N, Kondo Y, Nishizumi M. The effect of endurance training on the relationships between sex hormone binding globulin, high density lipoprotein cholesterol, apoprotein A1c and physical fitness in pre-menopausal women with mild obesity. Int J Obes Relat Metab Disord. 1994;18:249-254. (Pubitemid 24123460)
24. Selva DM, Hammond GL. Peroxisome-proliferator receptor γ represses hepatic sex hormone binding globulin expression. Endocrinology. 2009;150:2183-2189.
25. Oh JY, Barrett-Connor E, Wedick NM, Wingard DL. Endogenous sex hormones and the development of type 2 diabetes in older men and women: the Rancho Bernardo Study. Diabetes Care. 2002;25:55-60. (Pubitemid 41070783)
26. Kalyani RR, Franco M, Dobs AS, et al. The association of endogenous sex hormones, adiposity, and insulin resistance with incident diabetes in postmenopausal women. J Clin Endocrinol Metab. 2009;94:4127-4135.
27. Ding EL, Song Y, Manson JE, et al. Sex hormone-binding globulin and risk of type 2 diabetes in women and men. N Engl J Med. 2009;361:1152-1163.
28. Torrens J, Sutton-Tyrrell K, Zhao X, et al. Relative androgen excess during the menopausal transition predicts incident metabolic syndrome in midlife women: Study of Women's Health Across the Nation. Menopause. 2009;16:257-264.
29. Delahanty L, Peyrot M, Shrader P, Williamson D, Meigs J, Nathan D. Pretreatment, psychological, and behavioral predictors of weight outcomes among lifestyle intervention participants in the Diabetes Prevention Program (DPP). Diabetes Care. 2013;36:34-40.
30. Wildman R, Tepper P, Crawford S, et al. Do changes in sex steroid hormones precede or follow increases in body weight during the menopause transition? Results from the Study of Women's Health Across the Nation. J Clin Endocrinol Metab. 2012;97:E1695-E704.
31. Ratner RE, Christophi CA, Metzger B, et al Diabetes Prevention Program Research Group. Prevention of diabetes in women with a history of gestational diabetes:; effects of metformin and lifestyle interventions. J Clin Endocrinol Metab. 2008;93:4774-4779.
32. Hryjb DJ, Khan MS, Romas NA, Rosner W. The control of the interaction of sex hormone-binding globulin with its receptor by steroid hormones. J Biol Chem. 1990;265:6048-6054.
33. Burghen GA, Givens JR, Kitabchi AE. Correlation of hyperandrogenism with hyperinsulinism in polycystic ovarian disease. J Clin Endocrinol Metab. 1980;50:113-116. (Pubitemid 10203585)
34. Kitabchi AE, Imseis RE, Bush AJ, Williams-Cleaves B, Pourmotabbed G. Racial differences in the correlation between gonadal androgens and serum insulin levels. Diabetes Care. 1999;22:1524-1529. (Pubitemid 29418250)
35. Pinheiro SP, Holmes MD, Pollak MN, Barbieri RL, Hankinson SE. Racial differences in premenopausal endogenous hormones. Cancer Epidemiol Biomarkers Prev. 2005;14:2147-2153. (Pubitemid 41603260)
36. Welt CK, Arason G, Gudmundsson JA, et al. Defining constant versus variable phenotypic features of women with polcystic ovary syndrome using different ethnic groups and populations. J Clin Endocrinol Metab. 2006;91:4361-4368. (Pubitemid 44833410)
37. Bui HN, Sluss PM, Blincko S, Knol DL, Blankenstein MA, Heijboer AC. Dynamics of serum testosterone during the menstrual cycle evaluated by daily measurements with an ID-LC-MS/MS method and a 2nd generation automated immunoassay. Steroids. 2013;78:96-101.
38. Ahmad N, Pollard T, Unwin N. The optimal timing of blood collection during menstrual cycle for the assessment of endogenous sex hormones: can interindividual differences in levels over the whole cycle be assessed on a single day. Cancer Epidemiol Biomarkers Prev. 2002;11:147-151. (Pubitemid 34118326) Diseases Diseases Diseases Kidney Diseases Diseases