NOD-like receptors mediated activation of eosinophils interacting with bronchial epithelial cells: A link between innate immunity and allergic asthma

Cellular and Molecular Immunology

Volumn 10, Issue 4, 2013, Pages 317-329

  Wong, Chun Kwok ^a   Hu, Shuiqing ^a   Leung, Karen Ming Lam ^a   Dong, Jie ^a   He, Lan ^a   Chu, Yi Jun ^a   Chu, Ida Miu Ting ^a   Qiu, Huai Na ^a   Liu, Kelly Yan Ping ^a   Lam, Christopher Wai Kei ^a,b  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Macao)

Author keywords

allergy; bronchial epithelial cells; chemokines; eosinophils; signal transduction

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; CASPASE RECRUITMENT DOMAIN PROTEIN 4; CD18 ANTIGEN; DIAMINOPIMELIC ACID; IMMUNOGLOBULIN E; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 13; INTERLEUKIN 8; MITOGEN ACTIVATED PROTEIN KINASE; MONOCYTE CHEMOTACTIC PROTEIN 1; MURAMYL DIPEPTIDE; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR; RANTES;

ALLERGIC AIRWAY INFLAMMATION; ALLERGIC ASTHMA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; BACTERIAL INFECTION; BRONCHIAL EPITHELIAL CELL; BRONCHUS MUCOSA; CELL INTERACTION; CELL STRAIN; CELL SURFACE; CELLULAR IMMUNITY; COCULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; EOSINOPHIL; EXPERIMENTAL MOUSE; HUMAN; HUMAN CELL; IMMUNOGLOBULIN BLOOD LEVEL; INNATE IMMUNITY; LEUKOCYTE ACTIVATION; LIGAND BINDING; LUNG FIBROSIS; LUNG LAVAGE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; TH2 CELL; UPREGULATION;

ACETYLMURAMYL-ALANYL-ISOGLUTAMINE; ANIMALS; ANTIGENS, CD18; ASTHMA; BRONCHI; CELL COMMUNICATION; CELL LINE; CHEMOKINES; COCULTURE TECHNIQUES; DIAMINOPIMELIC ACID; EOSINOPHILS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; HUMANS; IMMUNITY, INNATE; INTERCELLULAR ADHESION MOLECULE-1; INTERLEUKIN-13; MICE; NF-KAPPA B; NOD1 SIGNALING ADAPTOR PROTEIN; NOD2 SIGNALING ADAPTOR PROTEIN; RESPIRATORY MUCOSA; TH2 CELLS;

BACTERIA (MICROORGANISMS); MUS;

EID: 84879931007     PISSN: 16727681     EISSN: None     Source Type: Journal    
DOI: 10.1038/cmi.2012.77     Document Type: Article

References (56)

1. Hogan SP, Rosenberg HF, Moqbel R, Phipps S, Foster PS, Lacy P et al. Eosinophils: biological propertiesand role in healthand disease. Clin Exp Allergy 2008; 38: 709-750. (Pubitemid 351550670)
2. Lemière C, Ernst P, Olivenstein R, Yamauchi Y, Govindaraju K, Ludwig MS et al. Airway inflammation assessed by invasive and noninvasive means in severe asthma: eosinophilic and noneosinophilic phenotypes. J Allergy Clin Immunol 2006; 118: 1033-1039. (Pubitemid 44666987)
3. Takafuji S, Ohtoshi T, Takizawa H, Tadokoro K, Ito K. Eosinophil degranulation in the presence of bronchial epithelial cells. Effect of cytokines and role of adhesion. J Immunol 1996; 156: 3980-3985. (Pubitemid 26137685)
4. Wong CK, Wang CB, Ip WK, Tian YP, Lam CW. Roleofp38 MAPKand NF-?B forchemokine release in co-cultureof human eosinophilsand bronchial epithelial cells. Clin Exp Immunol 2005; 139: 90-100. (Pubitemid 40066133)
5. Wang CB, Wong CK, Ip WK, Tian YP, Lam CW. Inductionof IL-6 inco-culture of bronchial epithelial cells and eosinophils is regulated by p38 MAPKand NF-?B. Allergy 2005; 60: 1378-1385. (Pubitemid 41476180)
6. Cheung PF, Wong CK, Ho AW, Hu S, Chen DP, Lam CW. Activation of human eosinophils and epidermal keratinocytes by Th2 cytokine IL-31: implicationfortheimmunopathogenesisofatopicdermatitis. Int Immunol 2010; 22: 453-467.
7. Schröder NW, Crother TR, Naiki Y, Chen S, Wong MH, Yilmaz A. Innate immune responses during respiratory tract infection with a bacterial pathogen induceallergicairwaysensitization. JAllergy Clin Immunol 2008; 122: 595-602.
8. Crother TR, Schröder NW, Karlin J, Chen S, Shimada K, Slepenkin A et al. Chlamydia pneumoniae infection induced allergic airway sensitization is controlled by regulatory T-cells and plasmacytoid dendritic cells. PLo S ONE2011; 6: e 20784.
9. 2 LEN-DARE systematic review. Allergy 2011; 66: 458-468.
10. Takeuchi O, Akira S. Pattern recognition receptorsand inflammation. Cell 2010; 140:805-820.
11. Carneiro LA, Magalhaes JG, Tattoli I, Philpott DJ, Travassos LH. NOD-like proteins in inflammation and disease. JPathol 2008; 214: 136-148. (Pubitemid 351160152)
12. Schroder K, Tschopp J. The inflammasomes. Cell 2010; 140: 821-832.
13. Tsuji Y, Watanabe T, Kudo M, Arai H, Strober W, Chiba T. Sensingof commensal organisms by the intracellular sensor NOD1 mediates experimental pancreatitis. Immunity 2012; 37: 326-338.
14. Sabbah A, Chang TH, Harnack R, Frohlich V, Tominaga K, Dube PH et al. Activation of innate immune antiviral responses by Nod2. Nat Immunol 2009; 10: 1073-1080.
15. Pedra JH, Cassel SL, Sutterwala FS. Sensing pathogens and danger signals by the inflammasome. Curr Opin Immunol 2009; 21: 10-16.
16. Magalhaes JG, Fritz JH, le Bourhis L, Sellge G, Travassos LH, Selvanantham T et al. Nod2-dependent Th2 polarization of antigen-specific immunity. J Immunol 2008; 181: 7925-7935.
17. Ogura Y, Bonen DK, Inohara N, Nicolae DL, Chen FF, Ramos R et al. A frame shift mutation in NOD2 associated with susceptibility to Crohn'sdisease. Nature 2001;411: 603-606. (Pubitemid 32531409)
18. Hysi P, Kabesch M, Moffatt MF, Schedel M, Carr D, Zhang Y. NOD1 variation, immunoglobulin Eandasthma. Hum Mol Genet 2005; 14: 935-941.
19. Rosenstiel P, Till A, Schreiber S. NOD-like receptors and human diseases. Microbes Infect 2007; 9: 648-657. (Pubitemid 46602024)
20. Kvarnhammar AM, Petterson T, Cardell LO. NOD-like receptorsand RIG-I-like receptors in human eosinophils: activation by NOD1 and NOD2 agonists. Immunology 2011; 134: 314-325.
21. Wang L, Cummings R, Usatyuk P, Morris A, Irani K, Natarajan V. Involvement of phospholipases D1 and D2 in sphingosine 1-phosphate-induced ERK (extracellular-signal-regulated kinase) activation and interleukin-8 secretion in human bronchial epithelial cells. Biochem J2002; 367: 751-760. (Pubitemid 35305714)
22. Mc Allister F, Henry A, Kreindler JL, Dubin PJ, Ulrich L, Steele C et al. Role of IL-17A, IL-17F, and the IL-17 receptor in regulating growth-related oncogenealpha and granulocyte colony-stimulating factor in bronchial epithelium: implications for airway inflammation in cystic fibrosis. J Immunol 2005; 175: 404-412. (Pubitemid 40884344)
23. Kawaguchi M, Kokubu F, Kuga H, Matsukura S, Hoshino H, Ieki K et al. Modulation of bronchial epithelial cells by IL-17. JAllergy Clin Immunol 2001; 108: 804-809. (Pubitemid 33096214)
24. Wong CK, Cao J, Yin YB, Lam CW. Interleukin-17A activation on bronchial epithelium and basophils: a novel inflammatory mechanism. Eur Respir J2010; 35: 883-893.
25. Beigelman A, Gunsten S, Mikols CL, Vidavsky I, Cannon CL, Brody SL et al. Azithromycin attenuatesairway inflammation in a noninfectious mouse model of allergic asthma. Chest 2009; 136: 498-506.
26. Barton JL, Berg T, Didon L, Nord M. The pattern recognition receptor Nod1 activates CCAAT/enhancer binding protein beta signalling in lungepithelial cells. Eur Respir J2007; 30: 214-222. (Pubitemid 47201722)
27. Farkas L, Stoelcker B, Jentsch N, Heitzer S, Pfeifer M. Muramyldipeptide modulates CXCL-8 release of BEAS-2B cells via NOD2. Scand J Immunol 2008; 68: 315-322.
28. Bérubé J, Bourdon C, Yao Y, Rousseau S. Distinct intracellular signaling pathways control the synthesis of IL-8 and RANTES in TLR1/TLR2, TLR3 or NOD1 activated human airway epithelial cells. Cell Signal 2009; 21: 448-456.
29. Cheung PF, Wong CK, Ip WK, Lam CW. FAK-mediated activation of ERK for eosinophil migration: a novel mechanism for infection-induced allergic inflammation. Int Immunol 2008; 20: 353-363. (Pubitemid 351321243)
30. Lal RB, Edison LJ, Chused TM. Fixation and long-term storage of human lymphocytes for surface marker analysis by flow cytometry. Cytometry 1988; 9: 213-219.
31. Holler E, Rogler G, Herfarth H, Brenmoehl J, Wild PJ, Hahn J et al. Both donor and recipient NOD2/CARD15 mutations associate with transplant-related mortality and Gv HD following allogeneic stem cell transplantation. Blood 2004; 104: 889-894. (Pubitemid 38970589)
32. Hugot JP. CARD15/NOD2 mutationsinCrohn'sdisease. Ann NYAcad Sci 2006; 1072: 9-18.
33. Reijmerink NE, Bottema RW, Kerkhof M, Gerritsen J, Stelma FF, Thijs C et al. TLR-related pathwayanalysis: novel gene-gene interactions in the development of asthma and atopy. Allergy 2010; 65: 199-207.
34. Weidinger S, Klopp N, Rümmler L, Wagenpfeil S, Baurecht HJ, Gauger A et al. Association of CARD15 polymorphisms with atopy-related traits in a population-based cohort of Caucasian adults. Clin Exp Allergy 2005; 35: 866-872. (Pubitemid 41032533)
35. Kawaguchi M, Kokubu F, Kuga H, Tomita T, Matsukura S, Kadokura M et al. Expression of eotaxin by normal airway epithelial cells after influenza virus A infection. Int Arch Allergy Immunol 2000; 122 (Suppl 1): 44-49. (Pubitemid 30326335)
36. Papadopoulos NG, Papi A, Meyer J, Stanciu LA, Salvi S, Holgate ST et al. Rhinovirus infection up-regulates eotaxin and eotaxin-2 expression in bronchial epithelial cells. Clin Exp Allergy 2001; 31: 1060-1066. (Pubitemid 32862836)
37. Bloemen PG, vandenTweel MC, Henricks PA, Engels F, Wagenaar SS, Rutten AA et al. Expressionand modulationof adhesion moleculeson human bronchial epithelial cells. Am J Respir Cell Mol Biol 1993; 9: 586-593. (Pubitemid 2028739)
38. Look DC, Rapp SR, Keller BT, Holtzman MJ. Selective induction of intercellular adhesion molecule-1 by interferon-in human airway epithelial cells. Am J Physiol 1992; 263: L79-87.
39. Cheung PF, Wong CK, Ip WK, Lam CW. IL-25regulatestheexpression of adhesion molecules on eosinophils: mechanism of eosinophilia in allergic inflammation. Allergy 2006; 61: 878-885. (Pubitemid 43893991)
40. Proud D, Leigh R. Epithelial cellsandairwaydiseases. Immunol Rev 2011; 242: 186-204.
41. Kitayama J, Fuhlbrigge RC, Puri KD, Springer TA. P-selectin, L-selectin, and alpha 4 integrin have distinct roles in eosinophil tethering and arrest on vascular endothelial cells under physiological flow conditions. J Immunol 1997; 159: 3929-3939. (Pubitemid 127469649)
42. Burke-Gaffney A, Hellewell PG. A CD18/ICAM-1-dependent pathway mediateseosinophil adhesion to human bronchial epithelial cells. Am J Respir Cell Mol Biol 1998; 19: 408-418. (Pubitemid 128354210)
43. Michail S, Mezoff E, Abernathy F. Role of selectins in the intestinal epithelial migrationofeosinophils. Pediatr Res 2005; 58: 644-647. (Pubitemid 41368890)
44. Spencer LA, Melo RC, Perez SA, Bafford SP, Dvorak AM, Weller PF. Cytokine receptor-mediated trafficking of preformed IL-4 in eosinophils identifies an innate immune mechanism of cytokine secretion. Proc Natl Acad Sci USA 2006; 103: 3333-3338. (Pubitemid 43346470)
45. Bandeira-Melo C, Sugiyama K, Woods LJ, Weller PF. Cutting edge: eotaxin elicits rapid vesicular transport-mediated release of preformed IL-4 from human eosinophils. J Immunol 2001; 166: 4813-4817. (Pubitemid 32280686)
46. Geddes BJ, Wang L, Huang WJ, Lavellee M, Manji GA. Human CARD12 is a novel CED4/Apaf-1 family member that induces apoptosis. Biochem Biophys Res Commun 2001; 284: 77-82. (Pubitemid 32924311)
47. Inohara M, Chamaillard M, Mc Donald C, Nuñez G. NOD-LRR proteins: role in host-microbial interactions and inflammatory disease. Annu Rev Biochem 2005; 74: 355-360.
48. Micheau O, Lens S, Gaide O, Alevizopoulos K, Tschopp J. NF-kappaB signals induce the expression of c-FLIP. Mol Cell Biol 2001; 21: 5299-5305. (Pubitemid 32702435)
49. Pauleau AL, Murray PJ. Roleof Nod2 in the response of macrophages to toll-like receptoragonists. Mol Cell Biol 2003; 23: 7531-7539. (Pubitemid 37271454)
50. Kobayashi KS, Chamaillard M, Ogura Y, Henegariu O, Inohara N, Nuñez G et al. Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science 2005; 307: 731-734. (Pubitemid 40194644)
51. Park JH, Kim YG, Shaw M, Kanneganti TD, Fujimoto Y, Fukase K et al. Nod1/RICK and TLR signaling regulate chemokine and antimicrobial innate immune responses in mesothelial cells. JImmunol 2007; 179: 514-521. (Pubitemid 46986568)
52. Cheung PF, Wong CK, Lam CW. Molecular mechanisms of cytokine and chemokine releasefrom eosinophilsactivated by IL-17A, IL-17F, and IL-23: implication for Th17 lymphocytes-mediated allergic inflammation. J Immunol 2008; 180: 5625-5635.
53. Netea MG, Azam T, Ferwerda G, Girardin SE, Walsh M, Park JS et al. IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism. Proc Natl Acad Sci USA 2005; 102: 16309-16314. (Pubitemid 41688910)
54. Fritz JH, Girardin SE, Fitting C, Werts C, Mengin-Lecreulx D, Caroff M et al. Synergisticstimulationof human monocytesand dendriticcells byToll-likereceptor4and NOD1-and NOD2-activating agonists. Eur JImmunol 2005; 35: 2459-2470.
55. Weigt SS, Elashoff RM, Keane MP, Strieter RM, Gomperts BN, Xue YY et al. Altered levelsofCCchemokines during pulmonaryCMV predict BOS and mortality post-lungtransplantation. Am J Transplant 2008; 8: 1512-1522. (Pubitemid 351989504)
56. Gueders MM, Paulissen G, Crahay C, Quesada-Calvo F, Hacha J, van Hove C et al. Mouse modelsof asthma:acomparison betweenC57BL/6 and BALB/ cstrainsregarding bronchial responsiveness, inflammation, and cytokine production. Inflamm Res 2009; 58: 845-854.