Icariside II induces apoptosis via inhibition of the EGFR pathways in A431 human epidermoid carcinoma cells

Molecular Medicine Reports

Volumn 8, Issue 2, 2013, Pages 597-602

  Wu, Jinfeng ^a   Zuo, Fuguo ^b   Du, Juan ^c   Wong, Pok Fai ^d   Qin, Haihong ^a   Xu, Jinhua ^a  

^a FUDAN UNIVERSITY   (China)

^b TONGJI UNIVERSITY   (China)

^c SECOND MILITARY MEDICAL UNIVERSITY   (China)

^d UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Apoptosis; Epidermal growth factor receptor; Epidermoid carcinoma; Icariside II

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; CASPASE 9; EPIDERMAL GROWTH FACTOR RECEPTOR; ICARIIN; ICARISIDE II; JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; STAT3 PROTEIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CARCINOMA CELL; CELL VIABILITY; CONTROLLED STUDY; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME INHIBITION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA; WESTERN BLOTTING;

APOPTOSIS; CARCINOMA, SQUAMOUS CELL; CASPASE 9; CELL LINE, TUMOR; CELL SURVIVAL; DRUGS, CHINESE HERBAL; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVONOIDS; HUMANS; POLY(ADP-RIBOSE) POLYMERASES; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS C-AKT; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR;

EID: 84879905034     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2013.1557     Document Type: Article

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