Sphingosine kinase-1 mediates endotoxemia-induced hyperinflammation in aged animals

Molecular Medicine Reports

Volumn 8, Issue 2, 2013, Pages 645-649

  Lufrano, Maria ^a,b   Jacob, Asha ^a,b   Zhou, Mian ^a,b   Wang, Ping ^a,b  

^a FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^b DONALD AND BARBARA ZUCKER SCHOOL OF MEDICINE AT HOFSTRA NORTHWELL   (United States)

Author keywords

Aged; Endotoxemia; Hyperinflammation; Sepsis; Sphingosine kinase 1

Indexed keywords

CD14 ANTIGEN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; SPHINGOSINE KINASE 1; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; ENDOTOXEMIA; GENE EXPRESSION; INFLAMMATION; JUVENILE; KUPFFER CELL; LIVER; MACROPHAGE; MALE; MEDIATOR; NONHUMAN; RAT; RETICULOENDOTHELIAL SYSTEM; SENESCENCE;

AGE FACTORS; ANIMALS; ANTIGENS, CD14; ENDOTOXEMIA; GENE EXPRESSION; INFLAMMATION; KUPFFER CELLS; LIPOPOLYSACCHARIDES; LIVER; MALE; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); RATS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

ANIMALIA; RATTUS; RODENTIA;

EID: 84879904572     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2013.1562     Document Type: Article

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