Determination of thyreostats in muscle and thyroid tissues by QuEChERS extraction and ultra-performance liquid chromatography tandem mass spectrometry

Food Additives and Contaminants - Part A

Volumn 30, Issue 6, 2013, Pages 949-957

  Lega, Francesca ^a   Contiero, Lidia ^a   Biancotto, Giancarlo ^a   Angeletti, Roberto ^a  

^a ISTITUTO ZOOPROFILATTICO SPERIMENTALE DELLE VENEZIE   (Italy)

Author keywords

LC MS MS; QuEChERS; thiouracil; thyreostats

Indexed keywords

DRUG PRODUCTS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MUSCLE;

COMMISSION DECISION 2002/657/EC; LC-MS/MS; PERFORMANCE CHARACTERISTICS; QUECHERS; TERATOGENIC PROPERTIES; THIOURACIL; THYREOSTATS; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

EXTRACTION;

2 BENZIMIDAZOLETHIOL DERIVATIVE; 2 MERCAPTOBENZOIMIDAZOLE; ACETIC ACID ETHYL ESTER; METHYLTHIOURACIL; PHENYLTHIOURACIL; PROPYLTHIOURACIL; THIAMAZOLE; THIOURACIL; THIOURACIL DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DERIVATIZATION; ELECTROSPRAY MASS SPECTROMETRY; EUROPEAN UNION; LIMIT OF DETECTION; LIQUID LIQUID EXTRACTION; MOLECULAR WEIGHT; MUSCLE; NONHUMAN; POULTRY; PRIORITY JOURNAL; REACTION TIME; REPRODUCIBILITY; TANDEM MASS SPECTROMETRY; THYROID GLAND; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

ANIMALIA;

EID: 84879892358     PISSN: 19440049     EISSN: 14645122     Source Type: Journal    
DOI: 10.1080/19440049.2013.780212     Document Type: Article

References (29)

1. Abuín S, Centrich F, Rúbies A, Companyó R, Prat MD. 2008. Analysis of thyreostatic drugs in thyroid samples by ultra-performance liquid chromatography tandem mass spectrometry detection. Anal Chim Acta. 617:184-191.
2. Abuín S, Companyó R, Centrich F, Rúbies A, Prat MD. 2008. Analysis of thyreostatic drugs in thyroid samples by liquid chromatography tandem mass spectrometry: comparison of two sample treatment strategies. J Chromatogr A. 1207:17-23.
3. Anastassiades M, Maštovská K, Lehotay SJ. 2003. Evaluation of analyte protectants to improve gas chromatographic analysis of pesticides. J Chromatogr A. 1015:163-184.
4. Asea PE, MacNeil JD, Boison JO. 2006. An analytical method to screen for six thyreostatic drug residues in the thyroid gland and muscle tissues of food producing animals by liquid chromatography with ultraviolet absorption detection and liquid chromatography/mass spectrometry. J AOAC Int. 89:567-575.
5. Blanchflower WJ, Hughes PJ, Andrew Cannavan A, McCoy MA, Kennedy DG. 1997. Determination of thyreostats in thyroid and urine using high-performance liquid chromatography-atmospheric pressure chemical ionisation mass spectrometry. Analyst. 122:967-972.
6. Courtheyn D, Le Bizec B, Brambilla G, De Brabander HF, Cobbaert M, Van De Wiele M, Vercammen J, De Wasch K. 2002. Recent developments in the use and abuse of growth promoters. Anal Chim Acta. 473:71-82.
7. De Brabander HF, Le Bizec B, Pinel G, Antignac JP, Verheyden K, Mortier V, Courtheyn D, Noppe H. 2007. Past, present and future of mass spectrometry in the analysis of residues of banned substances in meat-producing animals. J Mass Spectrom. 42:983-998.
8. De Wasch K, Be Brabander HF, Impens S, Vandewiele M, Courtheyn D. 2001. Determination of mercaptobenzimidazol and other thyreostat residues in thyroid tissue and meat using high-performance liquid chromatography-mass spectrometry original research. J Chromatogr A. 912:311-317.
9. European Community. 1981. Council Directive 81/602/EC. Off J Eur Comm L. 222:32-33.
10. European Community. 2002. Commission Decision (2002)/657/EC. Off J Eur Comm L. 221:8-36.
11. European Standard EN 15662:2008 Foods of plant origin - determination of pesticide residues using GC-MS and/or LC-MS/MS following acetonitrile extraction/partitioning and clean-up by dispersive SPE - QuEChERS-method.[Internet]. Available from: http://www.evs.ee/products/evs-en-15662-2008
12. European Union of Reference Laboratories. 2007. EURL guidance document: EURL's view on state of the art analytical methods for national residue control plans. [Internet]. [cited 2013 Mar 21]. Available from: http://www.bvl.bund.de/SharedDocs/Downloads/09_Untersuchungen/EURL_Empfehlungen_Konzentrationsauswahl_Methodenvalierungen_EN.pdf?__blob=publicationFile&v=2
13. International Agency for Research on Cancer. 2012. IARC monographs on the evaluation of carcinogenic risks to humans. [Internet]. Last update November 2012. [cited 2013 Mar 21]. Available from: http://monographs.iarc.fr/ENG/Classification/index.php/
14. ISO 11843-2:2000 Capability of detection - Part 2: methodology in the linear calibration case. Geneva: ISO. Available from: http://www.iso.org/iso/home/store/catalogue_tc/catalogue_detail.htm?csnumber=20186
15. ISO 5725-1:1994 Accuracy (trueness and precision) of measurement methods and results - Part 1: general principles and definitions. Geneva: ISO. Available from: http://www.iso.org/iso/iso_catalogue/catalogue_tc/catalogue_detail.htm?csnumber=11833
16. ISO/IEC Guide 99:2007 International vocabulary of metrology - Basic and general concepts and associated terms (VIM). Geneva: ISO. Available from: http://www.iso.org/iso/iso_catalogue/catalogue_tc/catalogue_detail.htm?csnumber=45324
17. Le Bizec B, Bichon E, Deceuninck Y, Prévost S, Monteau F, Antignac JP, Dervilly-Pinel G. 2011. Toward a criterion for suspect thiouracil administration in animal husbandry. Food Addit Contam. 28:840-847.
18. Lõhmus M, Kallaste K, Le Bizec B. 2009. Determination of thyreostats in urine and thyroid gland by ultra high performance liquid chromatography tandem mass spectrometry. J Chromatogr A. 1216:8080-8089.
19. Pinel G, Bichon E, Pouponneau K, Maume D, André F, Le Bizec B. 2005. Multi-residue method for the determination of thyreostats in urine samples using liquid chromatography coupled to tandem mass spectrometry after derivatization with 3-iodobenzylbromide. J Chromatogr A. 1085:247-252.
20. Pinel G, Mathieu S, Cesbron N, Maume D, De Brabander HF, André F, Le Bizec B. 2006. Evidence that urinary excretion of thiouracil in adult bovine submitted to a cruciferous diet can give erroneous indications of the possible illegal use of thyreostats in meat production. Food Addit Contam. 23:974-980.
21. Pinel G, Maume D, Deceuninck Y, Andre F, Le Bizec B. 2006. Unambigious identification of thiouracil residue in urine collected in non-treated bovine by tandem and high-resolution mass spectrometry. Rapid Commun Mass Spectrom. 20:3183-3187.
22. SANCO. 2008. SANCO/2004/2726-RE 4-December 2008 Guidelines for the implementation of Decision 2002/657/EC. [Internet]. Available from: http://ec.europa.eu/food/food/chemicalsafety/residues/cons_2004-2726rev4_en.pdf
23. Vanden Bussche J, Kiebooms JAL, De Clercq N, Deceuninck Y, Le Bizec B, De Brabander HF, Vanhaecke L. 2011. Feed and food responsible for the presence of low-level thiouracil in urine of livestock and humans? J Agric Food Chem. 59:5786-5792.
24. Vanden Bussche J, Noppe H, Verheyden K, Wille K, Pinel G, Le Bizec B, De Brabander HF. 2009. Analysis of thyreostats: a history of 35 years. Anal Chim Acta. 637:2-12.
25. Vanden Bussche J, Vanhaecke L, Deceuninck Y, Verheyden K, Wille K, Bekaert K, Le Bizec B, De Brabander HF. 2010. Development and validation of an ultra-high performance liquid chromatography tandem mass spectrometry method for quantifying thyreostats in urine without derivatisation. J Chromatogr A. 1217: 4285-4293.
26. Vanden Bussche J, Vanhaecke L, Deceuninck Y, Wille K, Bekaert K, Le Bizec B, De Brabander HF. 2011. Ultra-high performance liquid chromatography coupled to triple quadrupole mass spectrometry detection of naturally occurred thiouracil in urine of untreated livestock, domesticated animals and humans. Food Addit Contam. 28:166-172.
27. Verdon E, Couedor P, Sanders P. 2007. Multi-residue monitoring for the simultaneous determination of five nitrofurans (furazolidone, furaltadone, nitrofurazone, nitrofurantoine, nifursol) in poultry muscle tissue through the detection of their five major metabolites (AOZ, AMOZ, SEM, AHD, DNSAH) by liquid chromatography coupled to electrospray tandem mass spectrometry-In-house validation in line with Commission Decision 657/2002/EC. Anal Chim Acta. 586: 336-347.
28. Wozniak B, Zuchowska IM, Zmudzki J, Jedziniak P, Korycinska B, Sielska K, Witek S, Klopot A. 2011. Liquid chromatography tandem mass spectrometry with ion trap and triple quadrupole analyzers for determination of thyreostatic drugs in urine and muscle tissue. Anal Chim Acta. 700: 155-166.
29. Youden WJ, Steiner EH. 1975. Statistical manual of the AOAC - Association of Official Analytical Chemists. Washington (DC): AOAC-I; p. 35-ff.