-
1
-
-
0029128827
-
Syndromal mental retardation due to mutations in a regulator of gene expression
-
Gibbons R.J., Picketts D.J., Higgs D.R. Syndromal mental retardation due to mutations in a regulator of gene expression. Hum Mol Genet 1995, 4:1705.
-
(1995)
Hum Mol Genet
, vol.4
, pp. 1705
-
-
Gibbons, R.J.1
Picketts, D.J.2
Higgs, D.R.3
-
2
-
-
0034069652
-
Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation
-
Gibbons R.J., McDowell T.L., Raman S., O'Rourke D.M., Garrick D., Ayyub H., Higgs D.R. Mutations in ATRX, encoding a SWI/SNF-like protein, cause diverse changes in the pattern of DNA methylation. Nat Genet 2000, 24:368.
-
(2000)
Nat Genet
, vol.24
, pp. 368
-
-
Gibbons, R.J.1
McDowell, T.L.2
Raman, S.3
O'Rourke, D.M.4
Garrick, D.5
Ayyub, H.6
Higgs, D.R.7
-
3
-
-
38749117849
-
Loss of ATRX leads to chromosome cohesion and congression defects
-
Ritchie K., Seah C., Moulin J., Isaac C., Dick F., Berube N.G. Loss of ATRX leads to chromosome cohesion and congression defects. J Cell Biol 2008, 180:315.
-
(2008)
J Cell Biol
, vol.180
, pp. 315
-
-
Ritchie, K.1
Seah, C.2
Moulin, J.3
Isaac, C.4
Dick, F.5
Berube, N.G.6
-
4
-
-
3042780173
-
ATRX, a member of the SNF2 family of helicase/ATPases, is required for chromosome alignment and meiotic spindle organization in metaphase II stage mouse oocytes
-
De La Fuente R., Viveiros M.M., Wigglesworth K., Eppig J.J. ATRX, a member of the SNF2 family of helicase/ATPases, is required for chromosome alignment and meiotic spindle organization in metaphase II stage mouse oocytes. Dev Biol 2004, 272:1.
-
(2004)
Dev Biol
, vol.272
, pp. 1
-
-
De La Fuente, R.1
Viveiros, M.M.2
Wigglesworth, K.3
Eppig, J.J.4
-
5
-
-
77649262618
-
ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells
-
Wong L.H., McGhie J.D., Sim M., Anderson M.A., Ahn S., Hannan R.D., George A.J., Morgan K.A., Mann J.R., Choo K.H. ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells. Genome Res 2010, 20:351.
-
(2010)
Genome Res
, vol.20
, pp. 351
-
-
Wong, L.H.1
McGhie, J.D.2
Sim, M.3
Anderson, M.A.4
Ahn, S.5
Hannan, R.D.6
George, A.J.7
Morgan, K.A.8
Mann, J.R.9
Choo, K.H.10
-
6
-
-
13044252871
-
Localization of a putative transcriptional regulator (ATRX) at pericentromeric heterochromatin and the short arms of acrocentric chromosomes
-
McDowell T.L., Gibbons R.J., Sutherland H., O'Rourke D.M., Bickmore W.A., Pombo A., Turley H., Gatter K., Picketts D.J., Buckle V.J., et al. Localization of a putative transcriptional regulator (ATRX) at pericentromeric heterochromatin and the short arms of acrocentric chromosomes. Proc Natl Acad Sci U S A 1999, 96:13983.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 13983
-
-
McDowell, T.L.1
Gibbons, R.J.2
Sutherland, H.3
O'Rourke, D.M.4
Bickmore, W.A.5
Pombo, A.6
Turley, H.7
Gatter, K.8
Picketts, D.J.9
Buckle, V.J.10
-
7
-
-
77649099092
-
Distinct factors control histone variant H3.3 localization at specific genomic regions
-
Goldberg A.D., Banaszynski L.A., Noh K.M., Lewis P.W., Elsaesser S.J., Stadler S., Dewell S., Law M., Guo X., Li X., et al. Distinct factors control histone variant H3.3 localization at specific genomic regions. Cell 2010, 140:678.
-
(2010)
Cell
, vol.140
, pp. 678
-
-
Goldberg, A.D.1
Banaszynski, L.A.2
Noh, K.M.3
Lewis, P.W.4
Elsaesser, S.J.5
Stadler, S.6
Dewell, S.7
Law, M.8
Guo, X.9
Li, X.10
-
8
-
-
84870491209
-
Compromised genomic integrity impedes muscle growth after Atrx inactivation
-
Huh M.S., Price O'Dea T., Ouazia D., McKay B.C., Parise G., Parks R.J., Rudnicki M.A., Picketts D.J. Compromised genomic integrity impedes muscle growth after Atrx inactivation. J Clin Invest 2012, 122:4412.
-
(2012)
J Clin Invest
, vol.122
, pp. 4412
-
-
Huh, M.S.1
Price O'Dea, T.2
Ouazia, D.3
McKay, B.C.4
Parise, G.5
Parks, R.J.6
Rudnicki, M.A.7
Picketts, D.J.8
-
9
-
-
67649635974
-
Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication
-
Sfeir A., Kosiyatrakul S.T., Hockemeyer D., MacRae S.L., Karlseder J., Schildkraut C.L., de Lange T. Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication. Cell 2009, 138:90.
-
(2009)
Cell
, vol.138
, pp. 90
-
-
Sfeir, A.1
Kosiyatrakul, S.T.2
Hockemeyer, D.3
MacRae, S.L.4
Karlseder, J.5
Schildkraut, C.L.6
de Lange, T.7
-
10
-
-
65249186097
-
Non-B DNA conformations as determinants of mutagenesis and human disease
-
Bacolla A., Wells R.D. Non-B DNA conformations as determinants of mutagenesis and human disease. Mol Carcinog 2009, 48:273.
-
(2009)
Mol Carcinog
, vol.48
, pp. 273
-
-
Bacolla, A.1
Wells, R.D.2
-
11
-
-
68549136741
-
G-quadruplex structures: in vivo evidence and function
-
Lipps H.J., Rhodes D. G-quadruplex structures: in vivo evidence and function. Trends Cell Biol 2009, 19:414.
-
(2009)
Trends Cell Biol
, vol.19
, pp. 414
-
-
Lipps, H.J.1
Rhodes, D.2
-
12
-
-
84857163904
-
Small-molecule-induced DNA damage identifies alternative DNA structures in human genes
-
Rodriguez R., Miller K.M., Forment J.V., Bradshaw C.R., Nikan M., Britton S., Oelschlaegel T., Xhemalce B., Balasubramanian S., Jackson S.P. Small-molecule-induced DNA damage identifies alternative DNA structures in human genes. Nat Chem Biol 2012, 8:301.
-
(2012)
Nat Chem Biol
, vol.8
, pp. 301
-
-
Rodriguez, R.1
Miller, K.M.2
Forment, J.V.3
Bradshaw, C.R.4
Nikan, M.5
Britton, S.6
Oelschlaegel, T.7
Xhemalce, B.8
Balasubramanian, S.9
Jackson, S.P.10
-
13
-
-
79957556530
-
DNA replication through G-quadruplex motifs is promoted by the Saccharomyces cerevisiae Pif1 DNA helicase
-
Paeschke K., Capra J.A., Zakian V.A. DNA replication through G-quadruplex motifs is promoted by the Saccharomyces cerevisiae Pif1 DNA helicase. Cell 2011, 145:678.
-
(2011)
Cell
, vol.145
, pp. 678
-
-
Paeschke, K.1
Capra, J.A.2
Zakian, V.A.3
-
14
-
-
0035902465
-
In vitro generated antibodies specific for telomeric guanine-quadruplex DNA react with Stylonychia lemnae macronuclei
-
Schaffitzel C., Berger I., Postberg J., Hanes J., Lipps H.J., Pluckthun A. In vitro generated antibodies specific for telomeric guanine-quadruplex DNA react with Stylonychia lemnae macronuclei. Proc Natl Acad Sci U S A 2001, 98:8572.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 8572
-
-
Schaffitzel, C.1
Berger, I.2
Postberg, J.3
Hanes, J.4
Lipps, H.J.5
Pluckthun, A.6
-
15
-
-
77958494782
-
ATR-X syndrome protein targets tandem repeats and influences allele-specific expression in a size-dependent manner
-
Law M.J., Lower K.M., Voon H.P., Hughes J.R., Garrick D., Viprakasit V., Mitson M., De Gobbi M., Marra M., Morris A., et al. ATR-X syndrome protein targets tandem repeats and influences allele-specific expression in a size-dependent manner. Cell 2010, 143:367.
-
(2010)
Cell
, vol.143
, pp. 367
-
-
Law, M.J.1
Lower, K.M.2
Voon, H.P.3
Hughes, J.R.4
Garrick, D.5
Viprakasit, V.6
Mitson, M.7
De Gobbi, M.8
Marra, M.9
Morris, A.10
-
16
-
-
77953955724
-
The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3
-
Drane P., Ouararhni K., Depaux A., Shuaib M., Hamiche A. The death-associated protein DAXX is a novel histone chaperone involved in the replication-independent deposition of H3.3. Genes Dev 2010, 24:1253.
-
(2010)
Genes Dev
, vol.24
, pp. 1253
-
-
Drane, P.1
Ouararhni, K.2
Depaux, A.3
Shuaib, M.4
Hamiche, A.5
-
17
-
-
77956282773
-
Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres
-
Lewis P.W., Elsaesser S.J., Noh K.M., Stadler S.C., Allis C.D. Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres. Proc Natl Acad Sci U S A 2010, 107:14075.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 14075
-
-
Lewis, P.W.1
Elsaesser, S.J.2
Noh, K.M.3
Stadler, S.C.4
Allis, C.D.5
-
18
-
-
0742304304
-
Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis
-
Tagami H., Ray-Gallet D., Almouzni G., Nakatani Y. Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesis. Cell 2004, 116:51.
-
(2004)
Cell
, vol.116
, pp. 51
-
-
Tagami, H.1
Ray-Gallet, D.2
Almouzni, G.3
Nakatani, Y.4
-
19
-
-
84255162049
-
Dynamics of histone H3 deposition in vivo reveal a nucleosome gap-filling mechanism for H3.3 to maintain chromatin integrity
-
Ray-Gallet D., Woolfe A., Vassias I., Pellentz C., Lacoste N., Puri A., Schultz D.C., Pchelintsev N.A., Adams P.D., Jansen L.E., et al. Dynamics of histone H3 deposition in vivo reveal a nucleosome gap-filling mechanism for H3.3 to maintain chromatin integrity. Mol Cell 2011, 44:928.
-
(2011)
Mol Cell
, vol.44
, pp. 928
-
-
Ray-Gallet, D.1
Woolfe, A.2
Vassias, I.3
Pellentz, C.4
Lacoste, N.5
Puri, A.6
Schultz, D.C.7
Pchelintsev, N.A.8
Adams, P.D.9
Jansen, L.E.10
-
20
-
-
70149102225
-
The XNP remodeler targets dynamic chromatin in Drosophila
-
Schneiderman J.I., Sakai A., Goldstein S., Ahmad K. The XNP remodeler targets dynamic chromatin in Drosophila. Proc Natl Acad Sci U S A 2009, 106:14472.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 14472
-
-
Schneiderman, J.I.1
Sakai, A.2
Goldstein, S.3
Ahmad, K.4
-
21
-
-
0037058948
-
Histone H3 variants specify modes of chromatin assembly
-
Ahmad K., Henikoff S. Histone H3 variants specify modes of chromatin assembly. Proc Natl Acad Sci U S A 2002, 99(Suppl 4):16477.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.SUPPL 4
, pp. 16477
-
-
Ahmad, K.1
Henikoff, S.2
-
22
-
-
33750801681
-
The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres
-
Verdun R.E., Karlseder J. The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres. Cell 2006, 127:709.
-
(2006)
Cell
, vol.127
, pp. 709
-
-
Verdun, R.E.1
Karlseder, J.2
-
23
-
-
78649980436
-
Epigenetic instability due to defective replication of structured DNA
-
Sarkies P., Reams C., Simpson L.J., Sale J.E. Epigenetic instability due to defective replication of structured DNA. Mol Cell 2010, 40:703.
-
(2010)
Mol Cell
, vol.40
, pp. 703
-
-
Sarkies, P.1
Reams, C.2
Simpson, L.J.3
Sale, J.E.4
-
24
-
-
84857818879
-
FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA
-
Sarkies P., Murat P., Phillips L.G., Patel K.J., Balasubramanian S., Sale J.E. FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA. Nucleic Acids Res 2012, 40:1485.
-
(2012)
Nucleic Acids Res
, vol.40
, pp. 1485
-
-
Sarkies, P.1
Murat, P.2
Phillips, L.G.3
Patel, K.J.4
Balasubramanian, S.5
Sale, J.E.6
-
25
-
-
77953720192
-
ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks
-
Shanbhag N.M., Rafalska-Metcalf I.U., Balane-Bolivar C., Janicki S.M., Greenberg R.A. ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks. Cell 2010, 141:970.
-
(2010)
Cell
, vol.141
, pp. 970
-
-
Shanbhag, N.M.1
Rafalska-Metcalf, I.U.2
Balane-Bolivar, C.3
Janicki, S.M.4
Greenberg, R.A.5
-
27
-
-
0030697342
-
Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines
-
Bryan T.M., Englezou A., Dalla-Pozza L., Dunham M.A., Reddel R.R. Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines. Nat Med 1997, 3:1271.
-
(1997)
Nat Med
, vol.3
, pp. 1271
-
-
Bryan, T.M.1
Englezou, A.2
Dalla-Pozza, L.3
Dunham, M.A.4
Reddel, R.R.5
-
28
-
-
77955846020
-
Assaying and investigating alternative lengthening of telomeres activity in human cells and cancers
-
Henson J.D., Reddel R.R. Assaying and investigating alternative lengthening of telomeres activity in human cells and cancers. FEBS Lett 2010, 584:3800.
-
(2010)
FEBS Lett
, vol.584
, pp. 3800
-
-
Henson, J.D.1
Reddel, R.R.2
-
29
-
-
79960700556
-
Altered telomeres in tumors with ATRX and DAXX mutations
-
Heaphy C.M., de Wilde R.F., Jiao Y., Klein A.P., Edil B.H., Shi C., Bettegowda C., Rodriguez F.J., Eberhart C.G., Hebbar S., et al. Altered telomeres in tumors with ATRX and DAXX mutations. Science 2011, 333:425.
-
(2011)
Science
, vol.333
, pp. 425
-
-
Heaphy, C.M.1
de Wilde, R.F.2
Jiao, Y.3
Klein, A.P.4
Edil, B.H.5
Shi, C.6
Bettegowda, C.7
Rodriguez, F.J.8
Eberhart, C.G.9
Hebbar, S.10
-
30
-
-
79952279828
-
DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors
-
Jiao Y., Shi C., Edil B.H., de Wilde R.F., Klimstra D.S., Maitra A., Schulick R.D., Tang L.H., Wolfgang C.L., Choti M.A., et al. DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors. Science 2011, 331:1199.
-
(2011)
Science
, vol.331
, pp. 1199
-
-
Jiao, Y.1
Shi, C.2
Edil, B.H.3
de Wilde, R.F.4
Klimstra, D.S.5
Maitra, A.6
Schulick, R.D.7
Tang, L.H.8
Wolfgang, C.L.9
Choti, M.A.10
-
31
-
-
84864619205
-
Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway
-
Lovejoy C.A., Li W., Reisenweber S., Thongthip S., Bruno J., de Lange T., De S., Petrini J.H., Sung P.A., Jasin M., et al. Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway. PLoS Genet 2012, 8:e1002772.
-
(2012)
PLoS Genet
, vol.8
-
-
Lovejoy, C.A.1
Li, W.2
Reisenweber, S.3
Thongthip, S.4
Bruno, J.5
de Lange, T.6
De, S.7
Petrini, J.H.8
Sung, P.A.9
Jasin, M.10
-
32
-
-
84862777348
-
Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
-
Schwartzentruber J., Korshunov A., Liu X.Y., Jones D.T., Pfaff E., Jacob K., Sturm D., Fontebasso A.M., Quang D.A., Tonjes M., et al. Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. Nature 2012, 482:226.
-
(2012)
Nature
, vol.482
, pp. 226
-
-
Schwartzentruber, J.1
Korshunov, A.2
Liu, X.Y.3
Jones, D.T.4
Pfaff, E.5
Jacob, K.6
Sturm, D.7
Fontebasso, A.M.8
Quang, D.A.9
Tonjes, M.10
-
33
-
-
84863474126
-
Loss of ATRX or DAXX expression and concomitant acquisition of the alternative lengthening of telomeres phenotype are late events in a small subset of MEN-1 syndrome pancreatic neuroendocrine tumors
-
de Wilde R.F., Heaphy C.M., Maitra A., Meeker A.K., Edil B.H., Wolfgang C.L., Ellison T.A., Schulick R.D., Molenaar I.Q., Valk G.D., et al. Loss of ATRX or DAXX expression and concomitant acquisition of the alternative lengthening of telomeres phenotype are late events in a small subset of MEN-1 syndrome pancreatic neuroendocrine tumors. Mod Pathol 2012, 25:1033.
-
(2012)
Mod Pathol
, vol.25
, pp. 1033
-
-
de Wilde, R.F.1
Heaphy, C.M.2
Maitra, A.3
Meeker, A.K.4
Edil, B.H.5
Wolfgang, C.L.6
Ellison, T.A.7
Schulick, R.D.8
Molenaar, I.Q.9
Valk, G.D.10
-
34
-
-
71849103121
-
Transcriptional and developmental functions of the H3.3 histone variant in Drosophila
-
Sakai A., Schwartz B.E., Goldstein S., Ahmad K. Transcriptional and developmental functions of the H3.3 histone variant in Drosophila. Curr Biol 2009, 19:1816.
-
(2009)
Curr Biol
, vol.19
, pp. 1816
-
-
Sakai, A.1
Schwartz, B.E.2
Goldstein, S.3
Ahmad, K.4
-
35
-
-
78049434700
-
Loss of maternal ATRX results in centromere instability and aneuploidy in the mammalian oocyte and pre-implantation embryo
-
Baumann C., Viveiros M.M., De La Fuente R. Loss of maternal ATRX results in centromere instability and aneuploidy in the mammalian oocyte and pre-implantation embryo. PLoS Genet 2010, 6.
-
(2010)
PLoS Genet
, pp. 6
-
-
Baumann, C.1
Viveiros, M.M.2
De La Fuente, R.3
|