Anti-HLA-A, -B, -DR, -DQB1 and -DQA1 antibodies reactive epitope determination with HLAMatchmaker in multipare awaiting list for heart transplant

Human Immunology

Volumn 74, Issue 8, 2013, Pages 937-941

  Resse, Marianna ^a   Paolillo, Rossella ^a   Casamassimi, Amelia ^a   Cavalca, Francesco ^a   Fiorito, Carmela ^a   Maiello, Ciro ^a   Napoli, Claudio ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

HLA A ANTIGEN; HLA B ANTIGEN; HLA DQA1 ANTIGEN; HLA DQB1 ANTIGEN; HLA DR ANTIGEN;

ADULT; ALGORITHM; ALLELE; ARTICLE; CASE REPORT; CAUCASIAN; FEMALE; HEART FAILURE; HEART TRANSPLANTATION; HUMAN; IMMUNOREACTIVITY; ISCHEMIC HEART DISEASE; PREGNANCY; PRIORITY JOURNAL;

CDC; CDR; COMPLEMENT-DEPENDENT CYTOTOXICITY CROSSMATCH; COMPLEMENTARY DETERMINING REGION; ELISA; ENZYME-LINKED IMMUNOSORBENT ASSAY; HLA; HUMAN LEUKOCYTE ANTIGEN; MEAN FLUORESCENCE INTENSITY UNITS; MFI; PANEL REACTIVE ANTIBODY; PCR-SSP; POLYMERASE CHAIN REACTION-SEQUENCE-SPECIFIC PRIMER; PRA; SA; SINGLE ANTIGENS;

ADULT; ALLELES; ANTIBODIES; ANTIBODY SPECIFICITY; EPITOPES; FEMALE; HEART TRANSPLANTATION; HISTOCOMPATIBILITY; HISTOCOMPATIBILITY TESTING; HLA ANTIGENS; HUMANS; MIDDLE AGED;

EID: 84879884050     PISSN: 01988859     EISSN: 18791166     Source Type: Journal    
DOI: 10.1016/j.humimm.2013.04.033     Document Type: Article

References (29)

1. Ho E.K., Vlad G., Vasilescu E.R., de la Torre L., Colovai A.I., Burke E., et al. Pre-and post-transplantation allosensitization in heart allograft recipients: major impact of de novo alloantibody production on allograft survival. Hum Immunol 2011, 72:5-10.
2. Ferrari-Lacraz S., Tiercy J.M., Villard J. Detection of anti-HLA antibodies by solid-phase assay in kidney transplantation: friend or foe?. Tissue Antigens 2012, 79:315-325.
3. Ling M., Marfo K., Masiakos P., Aljanabi A., Lindower J., Glicklich D., et al. Pretransplant anti-HLA-Cw and Anti-HLA-DP antibodies in sensitized patients. Hum Immunol 2012, 73:879-883.
4. Amico P., Hönger G., Mayr M., Steiger J., Hopfer H., Schaub S. Clinical relevance of pretransplant donor-specific HLA antibodies detected by single-antigen flow-beads. Transplantation 2009, 87:1681-1688.
5. Minucci P.B., Grimaldi V., Casamassimi A., Cacciatore F., Sommese L., Picascia A., et al. Methodologies for anti-HLA antibody screening in patients awaiting kidney transplant: a comparative study. Exp Clin Transplant 2011, 9:381-386.
6. Taylor C.J., Kosmoliaptsis V., Summers D.M., Bradley J.A. Back to the future: application of contemporary technology to long-standing questions about the clinical relevance of human leukocyte antigen-specific alloantibodies in renal transplantation. Hum Immunol 2009, 70:563-568.
7. Muro M., González-Soriano M.J., Salgado G., López R., Boix F., López M., et al. Specific "intra-allele" and "intra-broad antigen" human leukocyte antigen alloantibodies in kidney graft transplantation. Hum Immunol 2010, 71:857-860.
8. Kosmoliaptsis V., Dafforn T.R., Chaudhry A.N., Halsall D.J., Bradley J.A., Taylor C.J. High-resolution, three-dimensional modeling of human leukocyte antigen class I structure and surface electrostatic potential reveals the molecular basis for alloantibody binding epitopes. Hum Immunol 2011, 72:1049-1059.
9. Duquesnoy R., Awadalla Y., Lomago J., Jelinek L., Howe J., Zern D., et al. Retransplant candidates have donor-specific antibodies that react with structurally defined HLA-DR, DQ, DP epitopes. Transpl Immunol 2008, 18:352-360.
10. Zeevi A., Girnita A., Duquesnoy R. HLA antibody analysis: sensitivity, specificity, and clinical significance in solid organ transplantation. Immunol Res 2006, 36:255-264.
11. MacCallum R.M., Martin A.C.R., Thornton J.M. Antibody-antigen interactions: contact analysis and binding site topography. J Mol Biol 1996, 262:732-745.
12. Getzoff E.D., Tainer J.A., Lerner R.A., Geysen H.M. The chemistry and mechanism of antibody binding to protein antigens. Adv Immunol 1988, 43:1-98.
13. Novotny J. Protein antigenicity: a thermodynamic approach. Mol Immunol 1991, 28:201-208.
14. Laune D., Molina F., Ferrieres G., Mani J.-C., Cohen P., Simon D., et al. Systematic exploration of the antigen binding activity of synthetic peptides isolated from the variable regions of immunoglobulins. J Biol Chem 1997, 272:30937-30944.
15. Bogan A.A., Thorn K.S. Anatomy of hot spots in protein interfaces. J Mol Biol 1998, 280:1-9.
16. Van Regenmortel M.H. Reductionism and the search for structure - function relationships in antibody molecules. J Mol Recognit 2002, 15:240-247.
17. Duquesnoy R.J., Mulder A., Askar M., Fernandez-Vina M., Claas F.H. HLAMatchmaker-based analysis of human monoclonal antibody reactivity demonstrates the importance of an additional contact site for specific recognition of triplet-defined epitopes. Hum Immunol 2005, 66:749-761.
18. Duquesnoy R.J., Marrari M. HLAMatchmaker-based definition of structural human leukocyte antigen epitopes detected by alloantibodies. Curr Opin Organ Transplant 2009, 14:403-409.
19. Duquesnoy R.J., Marrari M., Mulder A., Claas F.H., Mostecki J., Balazs I. Structural aspects of human leukocyte antigen class I epitopes detected by human monoclonal antibodies. Hum Immunol 2012, 73:267-277.
20. Zeevi A., Marrari M., Feingold B., Webber S., Duquesnoy R.J. Human leukocyte antigen epitope analysis to assess complement- and non-complement-binding donor-specific antibody repertoire in a pediatric heart transplant recipient. Hum Immunol 2012, 73:48-51.
21. James E., Chai J.G., Dewchand H., Macchiarulo E., Dazzi F., Simpson E. Multiparity induces priming to male-specific minor histocompatibility antigen, HY, in mice and humans. Blood 2003, 102:388-393.
22. Payne R., Rolfs M.R. Fetomaternal leukocyte incompatibility. J Clin Invest 1958, 37:1756-1763.
23. van Kampen C.A., Maarschalk M., Langerak-Langerak J., Roelen D.L., Claas F.H.J. Kinetics of the pregnancy-induced humoral and cellular immune response against the paternal HLA class I antigens of the child. Hum Immunol 2002, 63:452-458.
24. Duquesnoy R.J., Mulder A., Askar M., Fernandez-Vina M., Claas F.H.J. HLAMatchmaker-based analysis of human monoclonal antibody reactivity demonstrates the importance of an additional contact site for specific recognition of triplet-defined epitopes. Hum Immunol 2005, 66:749-761.
25. Duquesnoy R.J. HLAMatchmaker: a molecularly based algorithm for histocompatibility determination. ASHI Q 2002, 2:60-62.
26. Reinsmoen N.L., Lai C.H., Vo A., Cao K., Ong G., Naim M., et al. Acceptable donor-specific antibody levels allowing for successful deceased and living donor kidney transplantation after desensitization therapy. Transplantation 2008, 86:820-825.
27. Morris G.P., Phelan D.L., Jendrisak M.D., Mohanakumar T. Virtual crossmatch by identification of donor-specific anti-human leukocyte antigen antibodies by solid-phase immunoassay: a 30-month analysis in living donor kidney transplantation. Hum Immunol 2010, 71:268-273.
28. Gupta A., Iveson V., Varagunam M., Bodger S., Sinnott P., Thuraisingham R.C. Pretransplant donor-specific antibodies in cytotoxic negative crossmatch kidney transplants: are they relevant?. Transplantation 2008, 85:1200-1204.
29. Yanagida R., Czer L.S., Reinsmoen N.L., Cao K., Rafiei M., De Robertis M.A., et al. Impact of virtual cross match on waiting times for heart transplantation. Ann Thorac Surg 2011, 92:2104-2110.