Specific "intra-allele" and "intra-broad antigen" human leukocyte antigen alloantibodies in kidney graft transplantation

Human Immunology

Volumn 71, Issue 9, 2010, Pages 857-860

  Muro, Manuel ^a,b   González Soriano, María J ^b   Salgado, Gema ^b   López, Ruth ^b   Boix, Francisco ^b   López, Manuela ^b   Campillo, José A ^a,b   Martínez, Pedro ^b   Botella, Carmen ^b   Gimeno, Luisa ^b   Minguela, Alfredo ^a,b   Álvarez López, María R ^a,b   Llorente, Santiago ^b  

^a INSTITUTO DE SALUD CARLOS III   (Spain)

^b HOSPITAL GENERAL UNIVERSITARIO REINA SOFÍA   (Spain)

Author keywords

Crossmatching; Graft loss; HLA antibodies; Kidney transplant

Indexed keywords

ALLOANTIBODY; HLA ANTIGEN; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; HLA DR6 ANTIGEN; LEUKOCYTE ANTIGEN;

ADULT; ANTIBODY PRODUCTION; ARTICLE; BLOOD GROUP TYPING; CASE REPORT; COMPLEMENT DEPENDENT CYTOTOXICITY; GENE LOCUS; HUMAN; KIDNEY TRANSPLANTATION; MALE; PRIORITY JOURNAL;

ADULT; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; B-LYMPHOCYTES; COMPUTATIONAL BIOLOGY; CYTOTOXICITY TESTS, IMMUNOLOGIC; EPITOPES, B-LYMPHOCYTE; GRAFT REJECTION; GRAFT SURVIVAL; HISTOCOMPATIBILITY ANTIGENS CLASS I; HISTOCOMPATIBILITY ANTIGENS CLASS II; HISTOCOMPATIBILITY TESTING; HLA ANTIGENS; HLA-DP ANTIGENS; HLA-DQ ANTIGENS; HLA-DR ANTIGENS; HUMANS; ISOANTIBODIES; KIDNEY TRANSPLANTATION; MALE; MOLECULAR SEQUENCE DATA; POLYMORPHISM, GENETIC;

EID: 77956011344     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2010.05.018     Document Type: Article

References (21)

1. Terasaki P.I., Ozawa M. Predicting kidney graft failure by HLA antibodies: a prospective trial. Am J Transplant 2004, 4:438-443.
2. Piazza A., Poggi E., Ozzella G., Borrelli L., Monaco P.I., Scornajenghi A., et al. Public epitope specificity of HLA class I antibodies induced by failed transplant: alloantibody characterization by flow cytometric techniques. Transplantation 2006, 81:1298.
3. Piazza A., Ozzella G., Poggi E., Gennarelli D., Catalano M., Cremona R., Adorno D. Intra-broad antigens" and "intra-alleles" HLA alloantibodies 2008, Visuals of the European Clinical Histocompatibility Workshop, Canoga Park, CA. P.I. Terasaki (Ed.).
4. Muro M., Llorente S., Marín L., et al. Acute vascular rejection mediated by HLA antibodies in a cadaveric kidney recipient: discrepancies between FlowPRA™, ELISA and CDC vs Luminex screening. Nephr Dial Transpl 2005, 20:223-226.
5. Muro M., Rivera J., Botella C., Campillo J.A., Ferrer F., Álvarez-López M.R. HLA-DR antibodies in transfusion-related acute lung injury (TRALI): A case report. Transfus Apher Sci 2008, 38:209-212.
6. Mizutani K., Terasaki P., Hamdani E., Esquenazi V., Rosen A., Miller J., Ozawa M. The importance of anti-HLA-specific antibody strength in monitoring kidney transplant patients. Am J Transplant 2007, 7:1027-1031.
7. Howell M., Mutunga M., Pengilley R., Carter V. Use of Luminex technology for identification of HLA class I allele specific antibodies-occurrence and practicalities for clinical transplantation 2008, Visuals of the European Clinical Histocompatibility Workshop, Canoga Park, CA. P.I. Terasaki (Ed.).
8. Lucas D., Campillo J.A., López-Hernández R., Martínez-García P., López-Sánchez M., Botella C., et al. Allelic diversity of MICA gene and MICA/HLA-b haplotypic variation in a population of the Murcia region in southeastern Spain. Hum Immunol 2008, 69:655-660.
9. Elsner H.A., DeLuca D., Strub J., Blasczyk R. HistoCheck: rating of HLA class I and II mismatches by an internet-based software tool. Bone Marrow Transplant 2004, 33:165-169.
10. Duquesnoy R.J., Askar M. HLAMatchmaker: A molecularly based algorithm for histocompatibility determination. V. Eplet matching for HLA-DR, HLA-DQ, and HLA-DP. Hum Immunol 2007, 68:12-25.
11. Dankers M.K.A., Witvliet M.D., Roelen D., de Lange P., Korfage N., Persijn G.G., et al. The number of aminoacid triplet differences between patient and donor is predictive for the antibody reactivity against mismatched human leukocyte antigens. Transplantation 2004, 77:1236-1239.
12. Duquesnoy R.J. Human leukocyte antigen class II antibodies and transplant outcome. Transplantation 2008, 86:638-640.
13. Duquesnoy R.J., Awadalia Y., Lomago J., et al. Retransplant candidates have donor-specific antibodies that react with structurally defined HLA-DR, DQ, DP epitopes. Transpl Immunol 2008, 18:352-360.
14. Issa N., Cosio F., Gloor J., Sethi S., Dean P.G., Moore S.B., et al. Transplant glomerulopathy: risk and prognosis related to anti-human leukocyte antigen class II antibody levels. Transplantation 2008, 86:681-685.
15. Vongwiwatana A., Tasanarong A., Hidalgo L.G., Halloran P. The role of B cells and alloantibody in the host response to human organ allografts. Immunol Rev 2003, 196:197-218.
16. Muro M., Palacios S., Moya-Quiles M.R., Candela M., ́lvarez-López M.R. Acute haemolytic transfusion reaction secondary to HLA alloimmunization. Int J Lab Haematol 2008, 30:84-86.
17. Suarez-Alvarez B., López-Vázquez A., González M.Z., Fdez-Morera J.L., Díaz-Molina B., Blanco-Gelaz M.A., et al. The relationship of anti-MICA antibodies and MICA expression with heart allograft rejection. Am J Transplant 2007, 7:1842-1848.
18. Muro M., Marin L., Miras M., Moya-Quiles R., Minguela A., Sánchez-Bueno F., et al. Human liver allograft recipients harbouring anti-donor preformed lymphocytotoxic antibodies exhibit a poor graft survival at the first year after transplantation. Experience of one centre. Transpl Immunol 2005, 14:91-97.
19. Marin L., Torio A., Muro M., Fernandez-Parra R., Minguela A., Bosch V., et al. Alloimmune neonatal neutropenia and thrombocytopenia associated with maternal anti HNA-1a, HPA-3b and HLA antibodies. Pediatr Allergy Immunol 2005, 16:279-282.
20. El-awar N., Akaza T., Terasaki P.I., Nguyen A. Human leukocyte antigen class I epitope: updated to 103 total epitopes, including C locus. Transplantation 2007, 84:532.
21. Lomago J., Jelenik L., Zern D., Howe J., Martell J., Zeevi A., Duquesnoy R.J. How did a patient who types for HLA-B*4403 develop antibodies that react with HLA-B*4402?. Hum Immunol 2010, 71:176-178.