-
1
-
-
0037433442
-
Central challenges facing the national clinical research enterprise
-
DOI 10.1001/jama.289.10.1278
-
Sung NS, Crowley WF Jr., Genel M, et al. Central challenges facing the national clinical research enterprise. JAMA. 2003;289:1278-1287. (Pubitemid 37432909)
-
(2003)
Journal of the American Medical Association
, vol.289
, Issue.10
, pp. 1278-1287
-
-
Sung, N.S.1
Crowley Jr., W.F.2
Genel, M.3
Salber, P.4
Sandy, L.5
Sherwood, L.M.6
Johnson, S.B.7
Catanese, V.8
Tilson, H.9
Getz, K.10
Larson, E.L.11
Scheinberg, D.12
Reece, E.A.13
Slavkin, H.14
Dobs, A.15
Grebb, J.16
Martinez, R.A.17
Korn, A.18
Rimoin, D.19
-
2
-
-
33748062359
-
Clinical and Translational Science Awards: A framework for a national research agenda
-
DOI 10.1016/j.lab.2006.05.001, PII S0022214306001788
-
Zerhouni EA, Alving B. Clinical and translational science awards: a framework for a national research agenda. Transl Res. 2006;148:4-5. (Pubitemid 44302104)
-
(2006)
Translational Research
, vol.148
, Issue.1
, pp. 4-5
-
-
Zerhouni, E.A.1
Alving, B.2
-
3
-
-
64349091498
-
The NIH stimulus - The recovery act and biomedical research
-
Steinbrook R. The NIH stimulus-the recovery act and biomedical research. N Engl J Med. 2009;360:1479-1481.
-
(2009)
N Engl J Med
, vol.360
, pp. 1479-1481
-
-
Steinbrook, R.1
-
4
-
-
77950288852
-
Research funding. Health bill backs evidence-based medicine, new drug studies
-
Kaiser J. Research funding. Health bill backs evidence-based medicine, new drug studies. Science. 2010;327:1562.
-
(2010)
Science
, vol.327
, pp. 1562
-
-
Kaiser, J.1
-
5
-
-
77952987298
-
Using science to improve the nation's health system: NIH's commitment to comparative effectiveness research
-
Lauer MS, Collins FS. Using science to improve the nation's health system: NIH's commitment to comparative effectiveness research. JAMA. 2010;303:2182-2183.
-
(2010)
JAMA
, vol.303
, pp. 2182-2183
-
-
Lauer, M.S.1
Collins, F.S.2
-
7
-
-
76149096526
-
Launching HITECH
-
Blumenthal D. Launching HITECH. N Engl J Med. 2010;362:382-385.
-
(2010)
N Engl J Med
, vol.362
, pp. 382-385
-
-
Blumenthal, D.1
-
8
-
-
77952831095
-
Practice-based evidence for clinical practice improvement: An alternative study design for evidencebased medicine
-
Horn SD, Gassaway J, Pentz L, et al. Practice-based evidence for clinical practice improvement: an alternative study design for evidencebased medicine. Stud Health Technol Inform. 2010;151:446-460.
-
(2010)
Stud Health Technol Inform
, vol.151
, pp. 446-460
-
-
Horn, S.D.1
Gassaway, J.2
Pentz, L.3
-
9
-
-
84867222158
-
Improving the efficiency and effectiveness of pragmatic clinical trials in older adults in the United States
-
Saag KG, Mohr PE, Esmail L, et al. Improving the efficiency and effectiveness of pragmatic clinical trials in older adults in the United States. Contemp Clin Trials. 2012;33:1211-1216.
-
(2012)
Contemp Clin Trials
, vol.33
, pp. 1211-1216
-
-
Saag, K.G.1
Mohr, P.E.2
Esmail, L.3
-
11
-
-
36148951701
-
Influence of the HIPAA privacy rule on health research
-
DOI 10.1001/jama.298.18.2164
-
Ness RB. Influence of the HIPAA Privacy Rule on health research. JAMA. 2007;298:2164-2170. (Pubitemid 350106655)
-
(2007)
Journal of the American Medical Association
, vol.298
, Issue.18
, pp. 2164-2170
-
-
Ness, R.B.1
-
12
-
-
70149098761
-
Electronic medical records at a crossroads: Impetus for change or missed opportunity?
-
D'Avolio LW. Electronic medical records at a crossroads: impetus for change or missed opportunity? JAMA. 2009;302:1109-1111.
-
(2009)
JAMA
, vol.302
, pp. 1109-1111
-
-
D'avolio, L.W.1
-
13
-
-
69749119820
-
Toward reuse of clinical data for research and quality improvement: The end of the beginning?
-
Weiner MG, Embi PJ. Toward reuse of clinical data for research and quality improvement: the end of the beginning? Ann Intern Med. 2009;151:359-360.
-
(2009)
Ann Intern Med
, vol.151
, pp. 359-360
-
-
Weiner, M.G.1
Embi, P.J.2
-
14
-
-
27644587470
-
Effect of a clinical trial alert system on physician participation in trial recruitment
-
DOI 10.1001/archinte.165.19.2272
-
Embi PJ, Jain A, Clark J, et al. Effect of a clinical trial alert system on physician participation in trial recruitment. Arch Intern Med. 2005;165:2272-2277. (Pubitemid 41549924)
-
(2005)
Archives of Internal Medicine
, vol.165
, Issue.19
, pp. 2272-2277
-
-
Embi, P.J.1
Jain, A.2
Clark, J.3
Bizjack, S.4
Hornung, R.5
Martin Harris, C.6
-
15
-
-
41049094168
-
Using technology to promote gastrointestinal outcomes research: A case for electronic health records
-
Atreja A, Achkar J-P, Jain AK, et al. Using technology to promote gastrointestinal outcomes research: a case for electronic health records. Am J Gastroenterol. 2008;103:2171-2178.
-
(2008)
Am J Gastroenterol
, vol.103
, pp. 2171-2178
-
-
Atreja, A.1
Achkar, J.-P.2
Jain, A.K.3
-
16
-
-
49949093313
-
Development of a large-scale de-identified DNA biobank to enable personalized medicine
-
Roden DM, Pulley JM, Basford MA, et al. Development of a large-scale de-identified DNA biobank to enable personalized medicine. Clin Pharmacol Ther. 2008;84:362-369.
-
(2008)
Clin Pharmacol Ther
, vol.84
, pp. 362-369
-
-
Roden, D.M.1
Pulley, J.M.2
Basford, M.A.3
-
17
-
-
77952822074
-
PheWAS: Demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations
-
Denny JC, Ritchie MD, Basford MA, et al. PheWAS: demonstrating the feasibility of a phenome-wide scan to discover gene-disease associations. Bioinformatics. 2010;26:1205-1210.
-
(2010)
Bioinformatics
, vol.26
, pp. 1205-1210
-
-
Denny, J.C.1
Ritchie, M.D.2
Basford, M.A.3
-
18
-
-
77953170556
-
Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2)
-
Murphy SN, Weber G, Mendis M, et al. Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2). J Am Med Inform Assoc. 2010;17:124-130.
-
(2010)
J Am Med Inform Assoc
, vol.17
, pp. 124-130
-
-
Murphy, S.N.1
Weber, G.2
Mendis, M.3
-
19
-
-
77956261928
-
The utility of general purpose versus specialty clinical databases for research: Warfarin dose estimation from extracted clinical variables
-
Sagreiya H, Altman RB. The utility of general purpose versus specialty clinical databases for research: warfarin dose estimation from extracted clinical variables. J Biomed Inform. 2010;43:747-751.
-
(2010)
J Biomed Inform
, vol.43
, pp. 747-751
-
-
Sagreiya, H.1
Altman, R.B.2
-
20
-
-
84555206694
-
Patient reported outcomes in routine care: Advancing data capture for HIV cohort research
-
Kozak MS, Mugavero MJ, Ye J, et al. Patient reported outcomes in routine care: advancing data capture for HIV cohort research. CLin Infect Dis. 2012;54:141-147.
-
(2012)
CLin Infect Dis
, vol.54
, pp. 141-147
-
-
Kozak, M.S.1
Mugavero, M.J.2
Ye, J.3
-
21
-
-
69749100409
-
Design of a national distributed health data network
-
Maro JC, Platt R, Holmes JH, et al. Design of a national distributed health data network. Ann Intern Med. 2009;151:341-344.
-
(2009)
Ann Intern Med
, vol.151
, pp. 341-344
-
-
Maro, J.C.1
Platt, R.2
Holmes, J.H.3
-
22
-
-
69749110110
-
An electronic practice-based network for observational comparative effectiveness research
-
Pace WD, Cifuentes M, Valuck RJ, et al. An electronic practice-based network for observational comparative effectiveness research. Ann Intern Med. 2009;151:338-340.
-
(2009)
Ann Intern Med
, vol.151
, pp. 338-340
-
-
Pace, W.D.1
Cifuentes, M.2
Valuck, R.J.3
-
23
-
-
79955035027
-
Electronic medical records for genetic research: Results of the eMERGE consortium
-
Kho AN, Pacheco JA, Peissig PL, et al. Electronic medical records for genetic research: results of the eMERGE consortium. Sci Transl Med. 2011;3:79re71.
-
(2011)
Sci Transl Med
, vol.3
-
-
Kho, A.N.1
Pacheco, J.A.2
Peissig, P.L.3
-
24
-
-
79959654764
-
Mapping clinical phenotype data elements to standardized metadata repositories and controlled terminologies: The eMERGE Network experience
-
Pathak J, Wang J, Kashyap S, et al. Mapping clinical phenotype data elements to standardized metadata repositories and controlled terminologies: the eMERGE Network experience. J Am Med Inform Assoc. 2011;18:376-386.
-
(2011)
J Am Med Inform Assoc
, vol.18
, pp. 376-386
-
-
Pathak, J.1
Wang, J.2
Kashyap, S.3
-
25
-
-
67650886079
-
Practice-based research network studies and institutional review boards: Two new issues
-
Yawn BP, Graham DG, Bertram SL, et al. Practice-based research network studies and institutional review boards: two new issues. J Am Board Fam Med. 2009;22:453-460.
-
(2009)
J Am Board Fam Med
, vol.22
, pp. 453-460
-
-
Yawn, B.P.1
Graham, D.G.2
Bertram, S.L.3
-
26
-
-
84863542681
-
Evaluating alert fatigue over time to EHR-based clinical trial alerts: Findings from a randomized controlled study
-
Embi PJ, Leonard AC. Evaluating alert fatigue over time to EHR-based clinical trial alerts: findings from a randomized controlled study. J Am Med Inform Assoc. 2012;19:e145-e148.
-
(2012)
J Am Med Inform Assoc
, vol.19
-
-
Embi, P.J.1
Leonard, A.C.2
-
27
-
-
84862180522
-
Current state of information technologies for the clinical research enterprise across academic medical centers
-
Murphy SN, Dubey A, Embi PJ, et al. Current state of information technologies for the clinical research enterprise across academic medical centers. Clin Transl Sc. 2012;5:281-284.
-
(2012)
Clin Transl Sc
, vol.5
, pp. 281-284
-
-
Murphy, S.N.1
Dubey, A.2
Embi, P.J.3
-
28
-
-
33845429600
-
Toward a National Framework for the Secondary Use of Health Data: An American Medical Informatics Association White Paper
-
DOI 10.1197/jamia.M2273, PII S106750270600212X
-
Safran C, Bloomrosen M, Hammond WE, et al. Toward a national framework for the secondary use of health data: an American Medical Informatics Association White Paper. J Am Med Inform Assoc. 2007;14:1-9. (Pubitemid 44909487)
-
(2007)
Journal of the American Medical Informatics Association
, vol.14
, Issue.1
, pp. 1-9
-
-
Safran, C.1
Bloomrosen, M.2
Hammond, W.E.3
Labkoff, S.4
Markel-Fox, S.5
Tang, P.C.6
Detmer, D.E.7
-
29
-
-
0026775637
-
Evidence-based medicine. A new approach to teaching the practice of medicine
-
Group E-BMW
-
Group E-BMW. Evidence-based medicine. A new approach to teaching the practice of medicine. JAMA. 1992;268:2420-2425.
-
(1992)
JAMA
, vol.268
, pp. 2420-2425
-
-
-
30
-
-
67650001781
-
The obligation to participate in biomedical research
-
Schaefer GO, Emanuel EJ, Wertheimer A. The obligation to participate in biomedical research. JAMA. 2009;302:67-72.
-
(2009)
JAMA
, vol.302
, pp. 67-72
-
-
Schaefer, G.O.1
Emanuel, E.J.2
Wertheimer, A.3
-
32
-
-
33947316237
-
Moving closer to a rapid-learning health care system
-
Slutsky JR. Moving closer to a rapid-learning health care system. Health Aff (Millwood). 2007;26:w122-124.
-
(2007)
Health Aff (Millwood)
, vol.26
-
-
Slutsky, J.R.1
-
35
-
-
53149145726
-
Towards a data sharing culture: Recommendations for leadership from academic health centers
-
Piwowar HA, Becich MJ, Bilofsky H, et al. Towards a data sharing culture: recommendations for leadership from academic health centers. PLoS Med. 2008;5:e183.
-
(2008)
PLoS Med
, vol.5
-
-
Piwowar, H.A.1
Becich, M.J.2
Bilofsky, H.3
-
36
-
-
84855416409
-
Commentary: The relative research unit: Providing incentives for clinician participation in research activities
-
Embi PJ, Tsevat J. Commentary: the relative research unit: providing incentives for clinician participation in research activities. Acad Med. 2012;87:11-14.
-
(2012)
Acad Med
, vol.87
, pp. 11-14
-
-
Embi, P.J.1
Tsevat, J.2
-
37
-
-
73449122615
-
Biomedical informatics and outcomes research: Enabling knowledge-driven health care
-
Embi PJ, Kaufman SE, Payne PR. Biomedical informatics and outcomes research: enabling knowledge-driven health care. Circulation. 2009;120:2393-2399.
-
(2009)
Circulation
, vol.120
, pp. 2393-2399
-
-
Embi, P.J.1
Kaufman, S.E.2
Payne, P.R.3
-
38
-
-
84856620568
-
Natural language processing improves identification of colorectal cancer testing in the electronic medical record
-
Denny JC, Choma NN, Peterson JF, et al. Natural language processing improves identification of colorectal cancer testing in the electronic medical record. Med Decis Making. 2012;32:188-197.
-
(2012)
Med Decis Making
, vol.32
, pp. 188-197
-
-
Denny, J.C.1
Choma, N.N.2
Peterson, J.F.3
-
39
-
-
84855253927
-
Comparison of natural language processing biosurveillance methods for identifying influenza from encounter notes
-
Elkin PL, Froehling DA, Wahner-Roedler DL, et al. Comparison of natural language processing biosurveillance methods for identifying influenza from encounter notes. Ann Intern Med. 2012;156: 11-18.
-
(2012)
Ann Intern Med
, vol.156
, pp. 11-18
-
-
Elkin, P.L.1
Froehling, D.A.2
Wahner-Roedler, D.L.3
-
40
-
-
84863538060
-
Automated discovery of drug treatment patterns for endocrine therapy of breast cancer within an electronic medical record
-
Savova GK, Olson JE, Murphy SP, et al. Automated discovery of drug treatment patterns for endocrine therapy of breast cancer within an electronic medical record. J Am Med Inform Assoc. 2012;19:e83-e89.
-
(2012)
J Am Med Inform Assoc
, vol.19
-
-
Savova, G.K.1
Olson, J.E.2
Murphy, S.P.3
-
41
-
-
65349105048
-
Clinical research informatics: Challenges, opportunities and definition for an emerging domain
-
Embi PJ, Payne PR. Clinical research informatics: challenges, opportunities and definition for an emerging domain. J Am Med Inform Assoc. 2009;16:316-327.
-
(2009)
J Am Med Inform Assoc
, vol.16
, pp. 316-327
-
-
Embi, P.J.1
Payne, P.R.2
|