Serving the enterprise and beyond with informatics for integrating biology and the bedside (i2b2)

Journal of the American Medical Informatics Association

Volumn 17, Issue 2, 2010, Pages 124-130

  Murphy, Shawn N ^a,c   Weber, Griffin ^b,f   Mendis, Michael ^c   Gainer, Vivian ^c   Chueh, Henry C ^a   Churchill, Susanne ^c   Kohane, Isaac ^d,e  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c PARTNERS HEALTHCARE   (United States)

^d BOSTON CHILDREN S HOSPITAL   (United States)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

^f BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CLINICAL RESEARCH; COMPUTER PROGRAM; COMPUTER SECURITY; CONFIDENTIALITY; DATA ANALYSIS; DATA ANALYSIS SOFTWARE; DATA BASE; ELECTRONIC MEDICAL RECORD; INTERPERSONAL COMMUNICATION; MEDICAL INFORMATICS; MEDICAL INFORMATION SYSTEM; NATIONAL HEALTH ORGANIZATION; NATURAL LANGUAGE PROCESSING; NOMENCLATURE; OUTPATIENT CARE; PATIENT CARE; PATIENT INFORMATION; PRIVACY; COMPUTER INTERFACE; HUMAN; INFORMATION RETRIEVAL; MEDICAL RECORD; MEDICAL RESEARCH; ORGANIZATION AND MANAGEMENT; STATISTICS; SYSTEM ANALYSIS; UNITED STATES;

BIOMEDICAL RESEARCH; DATABASE MANAGEMENT SYSTEMS; HUMANS; INFORMATION STORAGE AND RETRIEVAL; MEDICAL RECORDS SYSTEMS, COMPUTERIZED; SOFTWARE; SYSTEMS INTEGRATION; UNITED STATES; USER-COMPUTER INTERFACE;

EID: 77953170556     PISSN: 10675027     EISSN: 1527974X     Source Type: Journal    
DOI: 10.1136/jamia.2009.000893     Document Type: Article

References (22)

1. Prokosch HU, Ganslandt T. Perspectives for medical informatics. Reusing the electronic medical record for clinical research. Methods Inf Med 2009;48:38-44.
2. Burgun A, Bodenreider O. Accessing and integrating data and knowledge for biomedical research. Yearb Med Inform 2008:91-101.
3. Ohmann C, Kuchinke W. Future developments of medical informatics from the viewpoint of networked clinical research. Interoperability and integration. Methods Inf Med 2009;48:45-54.
4. Haux R, Knaup P, Leiner F. On educating about medical data management - the other side of the electronic health record. Methods Inf Med 2007;46:74-9.
5. Tannen RL, Weiner MG, Xie D. Use of primary care electronic medical record database in drug efficacy research on cardiovascular outcomes: comparison of database and randomized controlled trial findings. BMJ 2009;338:b81.
6. America, Congress of USA. Title VIIIeHealth information technology 2009:241-277.
7. Murphy SN. Data warehousing for clinical research. In:Liu L, Tamer OM, eds. Encyclopedia of database systems Springer, 2009, ISBN: 978-0-387-49616-0.
8. Kimball R. The data warehousing toolkit New York: John Wiley, 1997.
9. Stead WW, Hammond WE, Straube MJ. A chartless recordeis it adequate? J Med Syst 1983;7:103-9.
10. Friedman C, Hripcsak G, Johnson SB, et al. A generalized relational schema for an integrated clinical patient database. In: Miller RA, ed. Proceedings of the fourteenth annual symposium on computer applications in medical care Los Alamitos, CA: IEEE Computer Society Press, 1990:335-9.
11. Nadkarni PM, Brandt C. Data extraction and Ad Hoc query of an entity-attributevalue database. J Am Med Inform Assoc 1998;5:511-7.
12. Johnson SB, Paut T, Khenima A. Generic database design for patient management information. Proc AMIA Annu Fall Symp 1997:22-6. (Pubitemid 127434436)
13. Murphy SN, Mendis M, Hackett K, et al. Architecture of the open-source clinical research chart from informatics for integrating biology and the bedside. AMIA Annu Symp Proc 2007;548-52.
14. Saltz J, Oster S, Hastings S, et al. CaGrid: design and implementation of the core architecture of the cancer biomedial informatics grid. Bioinformatics 2006;22:1910-6. (Pubitemid 44283037)
15. Zeng QT, Goryachev S, Weiss S, et al. Extracting principal diagnosis, co-morbidity and smoking status for asthma research: evaluation of a natural language processing system. BMC Medical Informatics and Decision Making 2006:6-30.
16. Murphy SN, Gainer VS, Chueh H. A visual interface designed for novice users to find research patient cohorts in a large biomedical database. AMIA Annu Symp Proc 2003:489-93.
17. Wang T, Plaisant C, Quinn A, et al. Aligning temporal data by sentinel events: discovering patterns in electronic health records. ACM Computer-Human Interaction 2008:457-66.
18. Murphy SN, Chueh H. A security architecture for query tools used to access large biomedical databases. Proc AMIA Symp 2002:552-6.
19. Eclipse Platform Technical Overview. The eclipse foundation (February 2003), http://www.eclipse.org/whitepapers/eclipse-overview.pdf.
20. Weber GM, Murphy SN, McMurry AJ, et al. The shared health research information network (SHRINE): a prototype federated query tool for clinical data repositories. J Am Med Inform Assoc 2009;16:624-30.
21. Himes BE, Dai Y, Kohane IS, et al. Prediction of chronic obstructive pulmonary disease (COPD) in asthma patients using electronic medical records. J Am Med Inform Assoc 2009;16:371-9.
22. Murphy S, Churchill S, Bry L, et al. Instrumenting the health care enterprise for discovery research in the genomic era. Genome Research 2009;19:1675-81.