Autoantibody diagnostics in neurology using native and recombinant antigenic substrates;Autoantikörperdiagnostik in der Neurologie mittels nativer und rekombinanter Antigensubstrate

Nervenarzt

Volumn 84, Issue 4, 2013, Pages 471-476

  Stocker W ^a   Saschenbrecker, S ^a   Rentzsch, K ^a   Komorowski, L ^a   Probst, C ^a  

^a Institut für Experimentelle Immunologie   (Germany)

Author keywords

Anti neuronal autoantibodies; Biochip mosaics; Cell based indirect immunofluorescence assay; Glutamate receptors; Neural cell surface

Indexed keywords

AUTOANTIBODY; RECOMBINANT ANTIGEN;

ARTICLE; BIOCHIP; CEREBELLUM; CEREBROSPINAL FLUID; HIPPOCAMPUS; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; KIDNEY CELL; NEUROLOGY; WESTERN BLOTTING;

ANTIGENS; AUTOANTIBODIES; AUTOIMMUNE DISEASES OF THE NERVOUS SYSTEM; BIOLOGICAL ASSAY; BIOLOGICAL MARKERS; ENCEPHALOMYELITIS; HUMANS; IMMUNOASSAY; IMMUNOTHERAPY; RECOMBINANT PROTEINS;

EID: 84879854102     PISSN: 00282804     EISSN: 14330407     Source Type: Journal    
DOI: 10.1007/s00115-012-3607-5     Document Type: Article

References (19)

1. Becker EB, Zuliani L, Pettingill R et al (2012) Contactin-associated protein-2 antibodies in non-paraneoplastic cerebellar ataxia. J Neurol Neurosurg Psychiatry 83:437-440
2. Bien CG, Vincent A, Barnett MH et al (2012) Immunopathology of autoantibody-associated encephalitides: clues for pathogenesis. Brain 135:1622-1638
3. Boronat A, Gelfand JM, Gresa-Arribas N et al (2012) Encephalitis and antibodies to DPPX, a subunit of Kv4.2 potassium channels. Ann Neurol. doi:10 1002/ana 23756
4. Dalmau J, Gleichman AJ, Hughes EG et al (2008) Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies. Lancet Neurol 7:1091-1098
5. Graaff E de, Maat P, Hulsenboom E et al (2012) Identification of delta/notch-like epidermal growth factor-related receptor as the Tr antigen in paraneoplastic cerebellar degeneration. Ann Neurol 71:815-824
6. Florance NR, Davis RL, Lam C et al (2009) Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis in children and adolescents. Ann Neurol 66:11-18
7. Graus F, Delattre JY, Antoine JC et al (2004) Recommended diagnostic criteria for paraneoplastic neurological syndromes. J Neurol Neurosurg Psychiatry 75:1135-1140 (Pubitemid 39005770)
8. Irani SR, Alexander S, Waters P et al (2010) Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan's syndrome and acquired neuromyotonia. Brain 133:2734-2748
9. Jarius S, Probst C, Borowski K et al (2010) Standardized method for the detection of antibodies to aquaporin-4 based on a highly sensitive immunofluorescence assay employing recombinant target antigen. J Neurol Sci 291:52-56
10. Lai M, Hughes EG, Peng X et al (2009) AMPA receptor antibodies in limbic encephalitis alter synaptic receptor location. Ann Neurol 65:424-434
11. Lancaster E, Dalmau J (2012) Neuronal autoantigens - pathogenesis, associated disorders and antibody testing. Nat Rev Neurol 8:380-390
12. Lancaster E, Lai M, Peng X et al (2010) Antibodies to the GABA(B) receptor in limbic encephalitis with seizures: case series and characterisation of the antigen. Lancet Neurol 9:67-76
13. Leypoldt F, Wandinger KP, Voltz R (2012) New developments in paraneoplastic neurological diseases. Akt Neurol 39:60-73
14. Lindstrom JM, Seybold ME, Lennon VA et al (1976) Antibody to acetylcholine receptor in myasthenia gravis. Prevalence, clinical correlates, and diagnostic value. Neurology 26:1054-1059
15. Pruss H, Dalmau J, Harms L et al (2010) Retrospective analysis of NMDA receptor antibodies in encephalitis of unknown origin. Neurology 75:1735-1739
16. Titulaer MJ, Soffietti R, Dalmau J et al (2011) Screening for tumours in paraneoplastic syndromes: report of an EFNS task force. Eur J Neurol 18:19-e3
17. Vincent A (2010) Autoimmune channelopathies: well-established and emerging immunotherapy-responsive diseases of the peripheral and central nervous systems. J Clin Immunol 30(Suppl 1):97-102
18. Vincent A, Buckley C, Schott JM et al (2004) Potassium channel antibody-associated encephalopathy: a potentially immunotherapy-responsive form of limbic encephalitis. Brain 127:701-712 (Pubitemid 38295483)
19. Voltz R (2002) Paraneoplastic neurological syndromes: an update on diagnosis, pathogenesis, and therapy. Lancet Neurol 1:294-305 (Pubitemid 37159173)