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Volumn 7, Issue 2, 2013, Pages 539-547

B cell-activating factor is associated with the histological severity of nonalcoholic fatty liver disease

Author keywords

Adipokine; B cell activating factor; Fibrosis; Hepatocyte ballooning; Nonalcoholic fatty liver disease; Nonalcoholic steatohepatitis

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; B CELL ACTIVATING FACTOR; COLLAGEN TYPE 4; FERRITIN; HYALURONIC ACID;

EID: 84879837384     PISSN: 19360533     EISSN: 19360541     Source Type: Journal    
DOI: 10.1007/s12072-012-9345-8     Document Type: Article
Times cited : (47)

References (45)
  • 1
    • 0037129380 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease
    • 11961152 10.1056/NEJMra011775 1:CAS:528:DC%2BD38XivVOmsrY%3D
    • Angulo P. Nonalcoholic fatty liver disease. N Engl J Med 2002;346:1221-1231
    • (2002) N Engl J Med , vol.346 , pp. 1221-1231
    • Angulo, P.1
  • 2
    • 0037299949 scopus 로고    scopus 로고
    • Non-alcoholic steatohepatitis: What is it, and why is it important in the Asia-Pacific region?
    • 12542595 10.1046/j.1440-1746.2003.02989.x
    • Farrell GC. Non-alcoholic steatohepatitis: what is it, and why is it important in the Asia-Pacific region? J Gastroenterol Hepatol 2003;18:124-138
    • (2003) J Gastroenterol Hepatol , vol.18 , pp. 124-138
    • Farrell, G.C.1
  • 3
    • 0037382786 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome
    • 12668987 10.1053/jhep.2003.50161
    • Marchesini G, Bugianesi E, Forlani G, et al. Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome. Hepatology 2003;37:917-923
    • (2003) Hepatology , vol.37 , pp. 917-923
    • Marchesini, G.1    Bugianesi, E.2    Forlani, G.3
  • 4
    • 22344453700 scopus 로고    scopus 로고
    • Natural history of NAFLD: Remarkably benign in the absence of cirrhosis
    • 16012969 10.1053/j.gastro.2005.05.041 1:STN:280:DC%2BD2MzlvVWksA%3D%3D
    • Day CP. Natural history of NAFLD: remarkably benign in the absence of cirrhosis. Gastroenterology 2005;129:375-378
    • (2005) Gastroenterology , vol.129 , pp. 375-378
    • Day, C.P.1
  • 5
    • 0028875908 scopus 로고
    • The natural history of nonalcoholic fatty liver: A follow-up study
    • 7489979 10.1002/hep.1840220616 1:STN:280:DyaK28%2FovVyhtQ%3D%3D
    • Teli MR, James OF, Burt AD, et al. The natural history of nonalcoholic fatty liver: a follow-up study. Hepatology 1995;22:1714-1719
    • (1995) Hepatology , vol.22 , pp. 1714-1719
    • Teli, M.R.1    James, O.F.2    Burt, A.D.3
  • 6
    • 22344452893 scopus 로고    scopus 로고
    • The natural history of nonalcoholic fatty liver disease: A population-based cohort study
    • 16012941 10.1053/j.gastro.2005.04.014
    • Adams LA, Lymp JF, St Sauver J, et al. The natural history of nonalcoholic fatty liver disease: a population-based cohort study. Gastroenterology 2005;129:113-121
    • (2005) Gastroenterology , vol.129 , pp. 113-121
    • Adams, L.A.1    Lymp, J.F.2    St Sauver, J.3
  • 7
    • 0033038672 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease: A spectrum of clinical and pathological severity
    • 10348825 10.1016/S0016-5085(99)70506-8 1:STN:280:DyaK1M3nvVamtw%3D%3D
    • Matteoni CA, Younossi ZM, Gramlich T, et al. Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. Gastroenterology 1999;116:1413-1419
    • (1999) Gastroenterology , vol.116 , pp. 1413-1419
    • Matteoni, C.A.1    Younossi, Z.M.2    Gramlich, T.3
  • 8
    • 58849134985 scopus 로고    scopus 로고
    • Long-term follow-up of patients with nonalcoholic fatty liver
    • 19049831 10.1016/j.cgh.2008.11.005
    • Rafiq N, Bai C, Fang Y, et al. Long-term follow-up of patients with nonalcoholic fatty liver. Clin Gastroenterol Hepatol 2009;7:234-238
    • (2009) Clin Gastroenterol Hepatol , vol.7 , pp. 234-238
    • Rafiq, N.1    Bai, C.2    Fang, Y.3
  • 9
    • 0023801758 scopus 로고
    • Alcohol like liver disease in nonalcoholics. A clinical and histologic comparison with alcohol-induced liver injury
    • 3410220 1:STN:280:DyaL1czhtlGjsQ%3D%3D
    • Diehl AM, Goodman Z, Ishak KG. Alcohol like liver disease in nonalcoholics. A clinical and histologic comparison with alcohol-induced liver injury. Gastroenterology 1988;95:1056-1062
    • (1988) Gastroenterology , vol.95 , pp. 1056-1062
    • Diehl, A.M.1    Goodman, Z.2    Ishak, K.G.3
  • 10
    • 0019152816 scopus 로고
    • Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease
    • 7382552 1:STN:280:DyaL3c3gvVeqtQ%3D%3D
    • Ludwig J, Viggiano TR, McGill DB, et al. Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease. Mayo Clin Proc 1980;55:434-438
    • (1980) Mayo Clin Proc , vol.55 , pp. 434-438
    • Ludwig, J.1    Viggiano, T.R.2    McGill, D.B.3
  • 11
    • 0031947715 scopus 로고    scopus 로고
    • Steatohepatitis: A tale of two "hits"?
    • 9547102 10.1016/S0016-5085(98)70599-2 1:STN:280:DyaK1c3htFartQ%3D%3D
    • Day CP, James OF. Steatohepatitis: a tale of two "hits"? Gastroenterology 1998;114:842-845
    • (1998) Gastroenterology , vol.114 , pp. 842-845
    • Day, C.P.1    James, O.F.2
  • 12
    • 0038644536 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis: Summary of an AASLD single topic conference
    • 12717402 10.1053/jhep.2003.50193
    • Neuschwander-Tetri BA, Caldwell SH. Nonalcoholic steatohepatitis: summary of an AASLD single topic conference. Hepatology 2003;37:1202-1219
    • (2003) Hepatology , vol.37 , pp. 1202-1219
    • Neuschwander-Tetri, B.A.1    Caldwell, S.H.2
  • 13
    • 18244364864 scopus 로고    scopus 로고
    • NASH and insulin resistance: Insulin hypersecretion and specific association with the insulin resistance syndrome
    • 11826411 10.1053/jhep.2002.30692 1:CAS:528:DC%2BD38XhsVGrt74%3D
    • Chitturi S, Abeygunasekera S, Farrell GC, et al. NASH and insulin resistance: insulin hypersecretion and specific association with the insulin resistance syndrome. Hepatology 2002;35:373-379
    • (2002) Hepatology , vol.35 , pp. 373-379
    • Chitturi, S.1    Abeygunasekera, S.2    Farrell, G.C.3
  • 14
    • 57349116780 scopus 로고    scopus 로고
    • Causes and metabolic consequences of fatty liver
    • 18723451 10.1210/er.2008-0009 1:CAS:528:DC%2BD1MXmt1yjug%3D%3D
    • Stefan N, Kantartzis K, Häring HU. Causes and metabolic consequences of fatty liver. Endocr Rev 2008;29:939-960
    • (2008) Endocr Rev , vol.29 , pp. 939-960
    • Stefan, N.1    Kantartzis, K.2    Häring, H.U.3
  • 15
    • 0035125052 scopus 로고    scopus 로고
    • The role of small intestinal bacterial overgrowth, intestinal permeability, endotoxaemia, and tumour necrosis factor alpha in pathogenesis of non-alcoholic steatohepatitis
    • 11156641 10.1136/gut.48.2.206 1:STN:280:DC%2BD3M7is1Wgtw%3D%3D
    • Wigg AJ, Roberts-Thomson IC, Dymock RB, et al. The role of small intestinal bacterial overgrowth, intestinal permeability, endotoxaemia, and tumour necrosis factor alpha in pathogenesis of non-alcoholic steatohepatitis. Gut 2001;48:206-211
    • (2001) Gut , vol.48 , pp. 206-211
    • Wigg, A.J.1    Roberts-Thomson, I.C.2    Dymock, R.B.3
  • 16
    • 41649093318 scopus 로고    scopus 로고
    • Inflammatory mechanisms in the regulation of insulin resistance
    • 18235842 10.2119/2007-00119.Tilg 1:CAS:528:DC%2BD1cXksVensrk%3D
    • Tilg H, Moschen AR. Inflammatory mechanisms in the regulation of insulin resistance. Mol Med 2008;14:222-231
    • (2008) Mol Med , vol.14 , pp. 222-231
    • Tilg, H.1    Moschen, A.R.2
  • 17
    • 0036732753 scopus 로고    scopus 로고
    • DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL
    • 12154359 10.1038/ni829 1:CAS:528:DC%2BD38Xms1ags7s%3D
    • Litinskiy MB, Nardelli B, Hilbert DM, et al. DCs induce CD40-independent immunoglobulin class switching through BLyS and APRIL. Nat Immunol 2002;3:822-829
    • (2002) Nat Immunol , vol.3 , pp. 822-829
    • Litinskiy, M.B.1    Nardelli, B.2    Hilbert, D.M.3
  • 18
    • 0035175146 scopus 로고    scopus 로고
    • Synthesis and release of B-lymphocyte stimulator from myeloid cells
    • 11133761 10.1182/blood.V97.1.198 1:CAS:528:DC%2BD3MXis1CisQ%3D%3D
    • Nardelli B, Belvedere O, Roschke V, et al. Synthesis and release of B-lymphocyte stimulator from myeloid cells. Blood 2001;97:198-204
    • (2001) Blood , vol.97 , pp. 198-204
    • Nardelli, B.1    Belvedere, O.2    Roschke, V.3
  • 19
    • 34247574625 scopus 로고    scopus 로고
    • B cells and the BAFF/APRIL axis: Fast-forward on autoimmunity and signaling
    • 17433868 10.1016/j.coi.2007.04.008 1:CAS:528:DC%2BD2sXlt1agtr8%3D
    • Mackay F, Silveira PA, Brink R. B cells and the BAFF/APRIL axis: fast-forward on autoimmunity and signaling. Curr Opin Immunol 2007;19:327-336
    • (2007) Curr Opin Immunol , vol.19 , pp. 327-336
    • Mackay, F.1    Silveira, P.A.2    Brink, R.3
  • 20
    • 33747837100 scopus 로고    scopus 로고
    • BAFF, APRIL and their receptors: Structure, function and signaling
    • 16914324 10.1016/j.smim.2006.04.006 1:CAS:528:DC%2BD28XoslOjtro%3D
    • Bossen C, Schneider P. BAFF, APRIL and their receptors: structure, function and signaling. Semin Immunol 2006;18:263-275
    • (2006) Semin Immunol , vol.18 , pp. 263-275
    • Bossen, C.1    Schneider, P.2
  • 21
    • 65949096493 scopus 로고    scopus 로고
    • B cell activation factor (BAFF) is a novel adipokine that links obesity and inflammation
    • 19293640 10.3858/emm.2009.41.3.024 1:CAS:528:DC%2BD1MXksVKkt78%3D
    • Kim YH, Choi BH, Cheon HG, et al. B cell activation factor (BAFF) is a novel adipokine that links obesity and inflammation. Exp Mol Med 2009;41:208-216
    • (2009) Exp Mol Med , vol.41 , pp. 208-216
    • Kim, Y.H.1    Choi, B.H.2    Cheon, H.G.3
  • 22
    • 42549123370 scopus 로고    scopus 로고
    • Expression of TNF-superfamily members BAFF and APRIL in breast cancer: Immunohistochemical study in 52 invasive ductal breast carcinomas
    • 18366696 10.1186/1471-2407-8-76
    • Pelekanou V, Kampa M, Kafousi M, et al. Expression of TNF-superfamily members BAFF and APRIL in breast cancer: immunohistochemical study in 52 invasive ductal breast carcinomas. BMC Cancer 2008;8:76
    • (2008) BMC Cancer , vol.8 , pp. 76
    • Pelekanou, V.1    Kampa, M.2    Kafousi, M.3
  • 23
    • 77950677297 scopus 로고    scopus 로고
    • Adipocytes as immune cells: Differential expression of TWEAK, BAFF, and APRIL and their receptors (Fn14, BAFF-R, TACI, and BCMA) at different stages of normal and pathological adipose tissue development
    • 19828625 10.4049/jimmunol.0901186 1:CAS:528:DC%2BD1MXht1ymurzI
    • Alexaki VI, Notas G, Pelekanou V, et al. Adipocytes as immune cells: differential expression of TWEAK, BAFF, and APRIL and their receptors (Fn14, BAFF-R, TACI, and BCMA) at different stages of normal and pathological adipose tissue development. J Immunol 2009;183:5948-5956
    • (2009) J Immunol , vol.183 , pp. 5948-5956
    • Alexaki, V.I.1    Notas, G.2    Pelekanou, V.3
  • 24
    • 80053274395 scopus 로고    scopus 로고
    • B cell-activating factor controls the production of adipokines and induces insulin resistance
    • 21701571 10.1038/oby.2011.165 1:CAS:528:DC%2BC3MXht1CktLvN
    • Hamada M, Abe M, Miyake T, et al. B cell-activating factor controls the production of adipokines and induces insulin resistance. Obesity 2011;19:1915-1922
    • (2011) Obesity , vol.19 , pp. 1915-1922
    • Hamada, M.1    Abe, M.2    Miyake, T.3
  • 25
    • 73649103759 scopus 로고    scopus 로고
    • Relationship between obesity and incident diabetes in middle-aged and older Japanese adults: The Ibaraki Prefectural Health Study
    • 20042559 10.4065/mcp.2009.0230 1:CAS:528:DC%2BC3cXht1ais7s%3D
    • Sasai H, Sairenchi T, Iso H, et al. Relationship between obesity and incident diabetes in middle-aged and older Japanese adults: the Ibaraki Prefectural Health Study. Mayo Clin Proc 2010;85:36-40
    • (2010) Mayo Clin Proc , vol.85 , pp. 36-40
    • Sasai, H.1    Sairenchi, T.2    Iso, H.3
  • 26
    • 38449111826 scopus 로고    scopus 로고
    • Diagnostic criteria for dyslipidemia. Executive summary of Japan Atherosclerosis Society (JAS) guideline for diagnosis and prevention of atherosclerotic cardiovascular diseases for Japanese
    • 17827859 10.5551/jat.E537 1:CAS:528:DC%2BD2sXhtFantbvP
    • Teramoto T, Sasaki J, Ueshima H, et al. Diagnostic criteria for dyslipidemia. Executive summary of Japan Atherosclerosis Society (JAS) guideline for diagnosis and prevention of atherosclerotic cardiovascular diseases for Japanese. J Atheroscler Thromb 2007;14:155-158
    • (2007) J Atheroscler Thromb , vol.14 , pp. 155-158
    • Teramoto, T.1    Sasaki, J.2    Ueshima, H.3
  • 27
    • 77952304034 scopus 로고    scopus 로고
    • The Japanese Society of Hypertension Guidelines for the management of hypertension (JSH 2009)
    • 19300436 1:CAS:528:DC%2BD1MXltVOjtLY%3D
    • Ogihara T, Kikuchi K, Matsuoka H, et al. The Japanese Society of Hypertension Guidelines for the management of hypertension (JSH 2009). Hypertens Res 2009;32:3-107
    • (2009) Hypertens Res , vol.32 , pp. 3-107
    • Ogihara, T.1    Kikuchi, K.2    Matsuoka, H.3
  • 28
    • 79952034925 scopus 로고    scopus 로고
    • Impaired dendritic cell functions disrupt antigen-specific adaptive immune responses in mice with nonalcoholic fatty liver disease
    • 20195647 10.1007/s00535-010-0218-4 1:CAS:528:DC%2BC3cXhtVSmtbvF
    • Miyake T, Akbar SM, Yoshida O, et al. Impaired dendritic cell functions disrupt antigen-specific adaptive immune responses in mice with nonalcoholic fatty liver disease. J Gastroenterol 2010;45:859-867
    • (2010) J Gastroenterol , vol.45 , pp. 859-867
    • Miyake, T.1    Akbar, S.M.2    Yoshida, O.3
  • 29
    • 24644492896 scopus 로고    scopus 로고
    • A technique for the measurement of visceral fat by ultrasonography: Comparison of measurements by ultrasonography and computed tomography
    • 16157975 10.2169/internalmedicine.44.794
    • Hirooka M, Kumagi T, Kurose K, et al. A technique for the measurement of visceral fat by ultrasonography: comparison of measurements by ultrasonography and computed tomography. Intern Med 2005;44:794-799
    • (2005) Intern Med , vol.44 , pp. 794-799
    • Hirooka, M.1    Kumagi, T.2    Kurose, K.3
  • 30
    • 20044374023 scopus 로고    scopus 로고
    • Design and validation of a histological scoring system for nonalcoholic fatty liver disease
    • 15915461 10.1002/hep.20701
    • Kleiner DE, Brunt EM, Van Natta M, et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology 2005;41:1313-21
    • (2005) Hepatology , vol.41 , pp. 1313-1321
    • Kleiner, D.E.1    Brunt, E.M.2    Van Natta, M.3
  • 31
    • 0033200054 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis: A proposal for grading and staging the histological lesions
    • 10484010 10.1111/j.1572-0241.1999.01377.x 1:STN:280:DyaK1MvhtFyisw%3D%3D
    • Brunt EM, Janney CG, Di Bisceglie AM, et al. Nonalcoholic steatohepatitis: a proposal for grading and staging the histological lesions. Am J Gastroenterol 1999;94:2467-2474
    • (1999) Am J Gastroenterol , vol.94 , pp. 2467-2474
    • Brunt, E.M.1    Janney, C.G.2    Di Bisceglie, A.M.3
  • 32
    • 18244382304 scopus 로고    scopus 로고
    • Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease
    • 15864352 1:CAS:528:DC%2BD2MXktFSktLk%3D
    • Donnelly KL, Smith CI, Schwarzenberg SJ, et al. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J Clin Invest 2005;115:1343-1351
    • (2005) J Clin Invest , vol.115 , pp. 1343-1351
    • Donnelly, K.L.1    Smith, C.I.2    Schwarzenberg, S.J.3
  • 33
    • 85047690933 scopus 로고    scopus 로고
    • Splanchnic lipolysis in human obesity
    • 15173884 1:CAS:528:DC%2BD2cXkvVOqtr8%3D
    • Nielsen S, Guo Z, Johnson CM, et al. Splanchnic lipolysis in human obesity. J Clin Invest 2004;113:1582-1588
    • (2004) J Clin Invest , vol.113 , pp. 1582-1588
    • Nielsen, S.1    Guo, Z.2    Johnson, C.M.3
  • 34
    • 0036217052 scopus 로고    scopus 로고
    • Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes
    • 11943743 10.1210/er.23.2.201 1:CAS:528:DC%2BD38XjsFWjtrw%3D
    • Lewis GF, Carpentier A, Adeli K, et al. Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes. Endocr Rev 2002;23:201-229
    • (2002) Endocr Rev , vol.23 , pp. 201-229
    • Lewis, G.F.1    Carpentier, A.2    Adeli, K.3
  • 35
    • 34249746761 scopus 로고    scopus 로고
    • Pathogenesis of non-alcoholic steatohepatitis: Human data
    • 17544973 10.1016/j.cld.2007.02.011
    • Edmison J, McCullough AJ. Pathogenesis of non-alcoholic steatohepatitis: human data. Clin Liver Dis 2007;11:75-104
    • (2007) Clin Liver Dis , vol.11 , pp. 75-104
    • Edmison, J.1    McCullough, A.J.2
  • 36
    • 33748946404 scopus 로고    scopus 로고
    • Gene expression of leptin, resistin, and adiponectin in the white adipose tissue of obese patients with non-alcoholic fatty liver disease and insulin resistance
    • 16989692 10.1381/096089206778392149
    • Baranova A, Gowder SJ, Schlauch K, et al. Gene expression of leptin, resistin, and adiponectin in the white adipose tissue of obese patients with non-alcoholic fatty liver disease and insulin resistance. Obes Surg 2006;16:1118-1125
    • (2006) Obes Surg , vol.16 , pp. 1118-1125
    • Baranova, A.1    Gowder, S.J.2    Schlauch, K.3
  • 37
    • 33746340885 scopus 로고    scopus 로고
    • Changes in serum adipokine levels during pioglitazone treatment for nonalcoholic steatohepatitis: Relationship to histological improvement
    • 16814613 10.1016/j.cgh.2006.05.005 1:CAS:528:DC%2BD28XptFWmt7w%3D
    • Lutchman G, Promrat K, Kleiner DE, et al. Changes in serum adipokine levels during pioglitazone treatment for nonalcoholic steatohepatitis: relationship to histological improvement. Clin Gastroenterol Hepatol 2006;4:1048-1052
    • (2006) Clin Gastroenterol Hepatol , vol.4 , pp. 1048-1052
    • Lutchman, G.1    Promrat, K.2    Kleiner, D.E.3
  • 38
    • 84862903129 scopus 로고    scopus 로고
    • Clinical significance of serum autoantibodies in patients with NAFLD: Results from the nonalcoholic steatohepatitis clinical research network
    • Epub ahead of print doi: 10.1007/s12072-011-9277-8
    • Vuppalanchi R, Gould RJ, Wilson LA et al. Clinical significance of serum autoantibodies in patients with NAFLD: results from the nonalcoholic steatohepatitis clinical research network. Hepatol Int (Epub ahead of print). 2011. doi: 10.1007/s12072-011-9277-8
    • (2011) Hepatol Int
    • Vuppalanchi, R.1    Gould, R.J.2    Wilson, L.A.3
  • 39
    • 0033923418 scopus 로고    scopus 로고
    • Appropriateness of liver biopsy
    • 10888734 1:STN:280:DC%2BD3czptlahsQ%3D%3D
    • Poynard T, Ratziu V, Bedossa P. Appropriateness of liver biopsy. Can J Gastroenterol 2000;14:543-548
    • (2000) Can J Gastroenterol , vol.14 , pp. 543-548
    • Poynard, T.1    Ratziu, V.2    Bedossa, P.3
  • 40
    • 77955690182 scopus 로고    scopus 로고
    • Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: The central role of nontriglyceride fatty acid metabolites
    • 20683968 10.1002/hep.23719
    • Neuschwander-Tetri BA. Hepatic lipotoxicity and the pathogenesis of nonalcoholic steatohepatitis: the central role of nontriglyceride fatty acid metabolites. Hepatology 2010;52:774-788
    • (2010) Hepatology , vol.52 , pp. 774-788
    • Neuschwander-Tetri, B.A.1
  • 41
    • 0032934278 scopus 로고    scopus 로고
    • Monocyte chemotactic protein-1 as a chemoattractant for human hepatic stellate cells
    • 9862860 10.1002/hep.510290107 1:CAS:528:DyaK1MXjslWntQ%3D%3D
    • Marra F, Romanelli RG, Giannini C, et al. Monocyte chemotactic protein-1 as a chemoattractant for human hepatic stellate cells. Hepatology 1999;29:140-148
    • (1999) Hepatology , vol.29 , pp. 140-148
    • Marra, F.1    Romanelli, R.G.2    Giannini, C.3
  • 42
    • 3042744737 scopus 로고    scopus 로고
    • Beyond insulin resistance in NASH: TNF-alpha or adiponectin?
    • 15239085 10.1002/hep.20280 1:CAS:528:DC%2BD2cXmtlSgtLY%3D
    • Hui JM, Hodge A, Farrell GC, et al. Beyond insulin resistance in NASH: TNF-alpha or adiponectin? Hepatology 2004;40:46-54
    • (2004) Hepatology , vol.40 , pp. 46-54
    • Hui, J.M.1    Hodge, A.2    Farrell, G.C.3
  • 43
    • 0036329894 scopus 로고    scopus 로고
    • Serum leptin in NASH correlates with hepatic steatosis but not fibrosis: A manifestation of lipotoxicity?
    • 12143049 10.1053/jhep.2002.34738 1:CAS:528:DC%2BD38XmsVansL0%3D
    • Chitturi S, Farrell G, Frost L, et al. Serum leptin in NASH correlates with hepatic steatosis but not fibrosis: a manifestation of lipotoxicity? Hepatology 2002;36:403-409
    • (2002) Hepatology , vol.36 , pp. 403-409
    • Chitturi, S.1    Farrell, G.2    Frost, L.3
  • 44
    • 9644265298 scopus 로고    scopus 로고
    • Leptin, insulin resistance, and liver fibrosis in human nonalcoholic fatty liver disease
    • 15582127 10.1016/j.jhep.2004.08.020 1:CAS:528:DC%2BD2cXhtVCgsLzF
    • Angulo P, Alba LM, Petrovic LM, et al. Leptin, insulin resistance, and liver fibrosis in human nonalcoholic fatty liver disease. J Hepatol 2004;41:943-949
    • (2004) J Hepatol , vol.41 , pp. 943-949
    • Angulo, P.1    Alba, L.M.2    Petrovic, L.M.3
  • 45
    • 70449706044 scopus 로고    scopus 로고
    • Adipokines in nonalcoholic steatohepatitis: From pathogenesis to implications in diagnosis and therapy
    • 19753129 10.1155/2009/831670
    • Tsochatzis EA, Papatheodoridis GV, Archimandritis AJ. Adipokines in nonalcoholic steatohepatitis: from pathogenesis to implications in diagnosis and therapy. Mediators Inflamm 2009;2009:831670 Technology
    • (2009) Mediators Inflamm , vol.2009 , pp. 831670
    • Tsochatzis, E.A.1    Papatheodoridis, G.V.2    Archimandritis, A.J.3


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