Pregnancy-associated plasma protein A predicts adverse vascular events in patients with coronary heart disease: A systematic review and meta-analysis

Archives of Medical Science

Volumn 9, Issue 3, 2013, Pages 389-397

  Li, Yuehua ^a   Zhou, Chenghui ^a   Zhou, Xianliang ^a   Li, Lihuan ^a   Hui, Rutai ^a  

^a FUWAI HOSPITAL   (China)

Author keywords

Coronary heart disease; Meta analysis; Mortality; Myocardial infarction; Pregnancy associated plasma protein A; Revascularization

Indexed keywords

PREGNANCY ASSOCIATED PLASMA PROTEIN A;

ALL CAUSE MORTALITY; CARDIOVASCULAR RISK; FOLLOW UP; HEART INFARCTION; HUMAN; ISCHEMIC HEART DISEASE; META ANALYSIS (TOPIC); MORTALITY; PREDICTION; PROSPECTIVE STUDY; REVIEW; SENSITIVITY ANALYSIS; SYSTEMATIC REVIEW (TOPIC);

EID: 84879801316     PISSN: 17341922     EISSN: None     Source Type: Journal    
DOI: 10.5114/aoms.2013.35421     Document Type: Review

References (46)

1. Lloyd-Jones D, Adams RJ, Brown TM, et al. Heart disease and stroke statistics - 2010 update: a report from the American Heart Association. Circulation 2010; 121: e46-215.
2. Mercando AD, Lai HM, Aronow WS, et al. Reduction in atherosclerotic events: a retrospective study in an outpatient cardiology practice. Arch Med Sci 2012; 8: 57-62.
3. Ross R. Atherosclerosis: an inflammatory disease. N Engl J Med 1999; 340: 115-26.
4. Glass CK, Witztum JL. Atherosclerosis. The Road Ahead. Cell 2001; 104: 503-16.
5. Dudziak J, Majewski M, Jerzykowska O, et al. Diagnostic value of circulating pregnancy-associated plasma protein a in atherosclerotic plaque rupture complications. Post Kardiol Interw 2011; 7: 302-10.
6. Iversen KK, Teisner AS, Teisner B, et al. Pregnancy-associated plasma protein A in non-cardiac conditions. Clin Biochem 2008; 41: 548-53.
7. Iversen KK, Teisner AS, Teisner B, et al. Pregnancy associated plasma protein A, a novel, quick, and sensitive marker in ST-elevation myocardial infarction. Am J Cardiol 2008; 101: 1389-94.
8. Hajek P, Macek M Sr, Lashkevich A, et al. Influence of concomitant heparin administration on pregnancy-associated plasma protein-A levels in acute coronary syndrome with ST segment elevation. Arch Med Sci 2011; 7: 977-83.
9. Bonaca MP, Scirica BM, Sabatine MS, et al. Prospective evaluation of pregnancy-associated plasma protein-A and outcomes in patients with acute coronary syndromes. J Am Coll Cardiol 2012; 60: 332-8.
10. Brugger-Andersen T, Aarsetoy H, Grundt H, et al. The long-term prognostic value of multiple biomarkers following a myocardial infarction. Thromb Res 2008; 123: 60-6.
11. Consuegra-Sanchez L, Petrovic I, Cosin-Sales J, et al. Prognostic value of circulating pregnancy-associated plasma protein-A (PAPP-A) and proform of eosinophil major basic protein (Pro-Mbp) levels in patients with chronic stable angina pectoris. Clin Chim Acta 2008; 391: 18-23.
12. Elesber AA, Conover CA, Denktas AE, et al. Prognostic value of circulating pregnancy-associated plasma protein levels in patients with chronic stable angina. Eur Heart J 2006; 27: 1678-84. (Pubitemid 44025354)
13. Heeschen C, Dimmeler S, Hamm CW, et al. Pregnancy-associated plasma protein-a levels in patients with acute coronary syndromes: comparison with markers of systemic inflammation, platelet activation, and myocardial necrosis. J Am Coll Cardiol 2005; 45: 229-37. (Pubitemid 40094730)
14. Iversen KK, Dalsgaard M, Teisner AS, et al. Usefulness of pregnancy-associated plasma protein A in patients with acute coronary syndrome. Am J Cardiol 2009; 104: 1465-71.
15. Iversen KK, Dalsgaard M, Teisner AS, et al. Pregnancy-associated plasma protein-a, a marker for outcome in patients suspected for acute coronary syndrome. Clin Biochem 2010; 43: 851-7.
16. Iversen KK, Teisner B, Winkel P, et al. Pregnancy associated plasma protein-A as a marker for myocardial infarction and death in patients with stable coronary artery disease: a prognostic study within the Claricor trial. Atherosclerosis 2011; 214: 203-8.
17. Kavsak PA, Wang X, Henderson M, et al. PAPP-A as a marker of increased long-term risk in patients with chest pain. Clin Biochem 2009; 42: 1012-8.
18. Laterza OF, Cameron SJ, Chappell D, et al. Evaluation of pregnancy-associated plasma protein A as a prognostic indicator in acute coronary syndrome patients. Clin Chim Acta 2004; 348: 163-9. (Pubitemid 39209015)
19. Lund J, Qin QP, Ilva T, et al. Circulating pregnancy-associated plasma protein A predicts outcome in patients with acute coronary syndrome but no troponin I elevation. Circulation 2003; 108: 1924-6. (Pubitemid 37296534)
20. Lund J, Wittfooth S, Qin QP, et al. Free vs. total pregnancy-associated plasma protein A (PAPP-A) as a predictor of 1-year outcome in patients presenting with non-ST-elevation acute coronary syndrome. Clin Chem 2010; 56: 1158-65.
21. Mei WY, Du ZM, Zhao Q, et al. Pregnancy-associated plasma protein predicts outcomes of percutaneous coronary intervention in patients with non-ST-elevation acute coronary syndrome. Heart Lung 2011; 40: e78-83.
22. Oemrawsingh RM, Lenderink T, Akkerhuis KM, et al. Multimarker risk model containing troponin-T, interleukin 10, myeloperoxidase and placental growth factor predicts long-term cardiovascular risk after non-ST-segment elevation acute coronary syndrome. Heart 2011; 97: 1061-6.
23. Schaub N, Reichlin T, Meune C, et al. Markers of plaque instability in the early diagnosis and risk stratification of acute myocardial infarction. Clin Chem 2012; 58: 246-56.
24. Schulz O, Reinicke M, Kramer J, et al. Pregnancy-associated plasma protein a values in patients with stable cardiovascular disease: use of a new monoclonal antibody-based assay. Clin Chim Acta 2011; 412: 880-6.
25. Boldt HB, Conover CA. Pregnancy-associated plasma protein-A (PAPP-A): a local regulator of IGF bioavailability through cleavage of IGFbps. Growth Horm IGF Res 2007; 17: 10-8.
26. Harrington SC, Simari RD, Conover CA. Genetic deletion of pregnancy-associated plasma protein-A is associated with resistance to atherosclerotic lesion development in apolipoprotein E-deficient mice challenged with a high-fat diet. Circ Res 2007; 100: 1696-702. (Pubitemid 46987861)
27. Lawrence JB, Oxvig C, Overgaard MT, et al. The insulin-like growth factor (IGF)-dependent IGF binding protein-4 protease secreted by human fibroblasts is pregnancy-associated plasma protein-A. Proc Natl Acad Sci U S A 1999; 96: 3149-53. (Pubitemid 29148859)
28. Conover CA, Harrington SC, Bale LK. Differential regulation of pregnancy associated plasma protein-A in human coronary artery endothelial cells and smooth muscle cells. Growth Horm IGF Res 2008; 18: 213-20. (Pubitemid 351479925)
29. Conover CA, Bale LK, Harrington SC, et al. Cytokine stimulation of pregnancy-associated plasma protein A expression in human coronary artery smooth muscle cells: inhibition by Resveratrol. Am J Physiol Cell Physiol 2006; 290: C183-8.
30. Bayes-Genis A, Conover CA, Schwartz RS. The insulin-like growth factor axis: a review of atherosclerosis and restenosis. Circ Res 2000; 86: 125-30. (Pubitemid 30086171)
31. Bayes-Genis A, Conover CA, Overgaard MT, et al. Pregnancy-associated plasma protein A as a marker of acute coronary syndromes. N Engl J Med 2001; 345: 1022-9.
32. Conover CA, Mason MA, Bale LK, et al. Transgenic over-expression of pregnancy-associated plasma protein-A in murine arterial smooth muscle accelerates athero sclerotic lesion development. Am J Physiol Heart Circ Physiol 2010; 299: H284-91.
33. Stroup DF, Berlin JA, Morton SC, et al. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis of observational studies in epidemiology (Moose) Group. JAMA 2000; 283: 2008-12. (Pubitemid 30214957)
34. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials 1986; 7: 177-88. (Pubitemid 17189972)
35. Egger M, Davey Smith G, Schneider M, et al. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997; 315: 629-34. (Pubitemid 27387172)
36. Sangiorgi G, Mauriello A, Bonanno E, et al. Pregnancy-associated plasma protein-A is markedly expressed by monocyte-macrophage cells in vulnerable and ruptured carotid atherosclerotic plaques: a link between inflammation and cerebrovascular events. J Am Coll Cardiol 2006; 47: 2201-11. (Pubitemid 43795064)
37. Resch ZT, Simari RD, Conover CA. Targeted disruption of the pregnancy-associated plasma protein-A gene is associated with diminished smooth muscle cell response to insulin-like growth factor-I and resistance to neointimal hyperplasia after vascular injury. Endocrinology 2006; 147: 5634-40. (Pubitemid 44833480)
38. Cosin-Sales J, Christiansen M, Kaminski P, et al. Pregnancy-associated plasma protein A and its endo genous inhibitor, the proform of eosinophil major basic protein (Prombp), are related to complex stenosis morphology in patients with stable angina pectoris. Circulation 2004; 109: 1724-8. (Pubitemid 38500673)
39. Cosin-Sales J, Kaski JC, Christiansen M, et al. Relationship among pregnancy associated plasma protein-A levels, clinical characteristics, and coronary artery disease extent in patients with chronic stable angina pectoris. Eur Heart J 2005; 26: 2093-8. (Pubitemid 41407989)
40. Resch ZT, Chen BK, Bale LK, et al. Pregnancy-associated plasma protein A gene expression as a target of inflammatory cytokines. Endocrinology 2004; 145: 1124-9. (Pubitemid 38280991)
41. Sabatine MS, Morrow DA, de Lemos JA, et al. Multimarker approach to risk stratification in non-ST elevation acute coronary syndromes: simultaneous assessment of troponin I, C-reactive protein, and B-type natriuretic peptide. Circulation 2002; 105: 1760-3. (Pubitemid 34408881)
42. Biasillo G, Leo M, Della Bona R, et al. Inflammatory biomarkers and coronary heart disease: from Bench to bedside and back. Intern Emerg Med 2010; 5: 225-33.
43. Morrow DA, Cannon CP, Jesse RL, et al. National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines: clinical characteristics and utilization of biochemical markers in acute coronary syndromes. Circulation 2007; 115: e356-75. (Pubitemid 46648624)
44. Li Y, Zhou C, Zhou X, et al. PAPP-A in cardiac and noncardiac conditions. Clin Chim Acta 2013; 417: 67-72.
45. Bulut I, Coskun A, Ciftci A, et al. Relationship between pregnancy-associated plasma protein-A and lung cancer. Am J Med Sci 2009; 337: 241-4.
46. Etter C, Straub Y, Hersberger M, et al. Pregnancy-associated plasma protein-A is an independent short-time predictor of mortality in patients on maintenance haemodialysis. Eur Heart J 2010; 31: 354-9.