Memory phenotype and polyfunctional T cells in kidney transplant patients

Transplant Immunology

Volumn 28, Issue 2-3, 2013, Pages 127-137

  Ortiz, Yaneth M ^a   Arias, Luis F ^a   Álvarez, Cristiam M ^a   García, Luis F ^a  

^a UNIVERSIDAD DE ANTIOQUIA   (Colombia)

Author keywords

Acceptance; Kidney transplant; Polyfunctional T cells; Rejection; T cell memory phenotype

Indexed keywords

CD27 ANTIGEN; CD4 ANTIGEN; CD45RO ANTIGEN; CD8 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 2; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ANTIGEN EXPRESSION; ARTICLE; CELLULAR DISTRIBUTION; CHRONIC GRAFT REJECTION; CLINICAL ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; EFFECTOR CELL; EX VIVO STUDY; FEMALE; GRAFT SURVIVAL; HEMODIALYSIS PATIENT; HUMAN; HUMAN CELL; KIDNEY GRAFT REJECTION; KIDNEY TRANSPLANTATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; MALE; MEMORY T LYMPHOCYTE; PHENOTYPE; PRIORITY JOURNAL; SURVIVAL RATE; T LYMPHOCYTE SUBPOPULATION;

EID: 84879796541     PISSN: 09663274     EISSN: 18785492     Source Type: Journal    
DOI: 10.1016/j.trim.2013.02.003     Document Type: Article

References (40)

1. Sallusto F, Geginat J, Lanzavecchia A. Central memory and effector memory T cell subsets: function, generation, and maintenance. Annu Rev Immunol 2004;22: 745-63.
2. Moulton VR, Farber DL. Committed to memory: lineage choices for activated T cells. Trends Immunol 2006;27:261-7.
3. Sallusto F, Lanzavecchia A. Exploring pathways for memory T cell generation. J Clin Invest 2001;108:805-6.
4. Sallusto F, Lenig D, Forster R, Lipp M, Lanzavecchia A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 1999;401:708-12.
5. Heeger PS, Greenspan NS, Kuhlenschmidt S, Dejelo C, Hricik DE, Schulak JA, et al. Pretransplant frequency of donor-specific, IFN-gamma-producing lymphocytes is a manifestation of immunologic memory and correlates with the risk of posttransplant rejection episodes. J Immunol 1999;163:2267-75.
6. Chalasani GML, Fadi GMD. Immunologic ignorance of organ allografts. Curr Opin Organ Transplant 2001;6:83-8.
7. Lombardi G, Sidhu S, Daly M, Batchelor JR, Makgoba W, Lechler RI. Are primary alloresponses truly primary?. Int Immunol 1990;2:9-13.
8. Ibrahim S, Dawson DV, Van Trigt P, Sanfilippo F. Differential infiltration by CD45RO and CD45RA subsets of T cells associated with human heart allograft rejection. Am J Pathol 1993;142:1794-803.
9. Ibrahim S, Dawson DV, Sanfilippo F. Predominant infiltration of rejecting human renal allografts with T cells expressing CD8 and CD45RO. Transplantation 1995;59: 724-8.
10. Dollinger MM, Howie SE, Plevris JN, Graham AM, Hayes PC, Harrison DJ. Intrahepatic proliferation of 'naive' and 'memory' T cells during liver allograft rejection: primary immune response within the allograft. FASEB J 1998;12:939-47.
11. Macedo C, Orkis EA, Popescu I, Elinoff BD, Zeevi A, Shapiro R, et al. Contribution of naive and memory T-cell populations to the human alloimmune response. Am J Transplant 2009;9:2057-66.
12. Valujskikh A, Pantenburg B, Heeger PS. Primed allospecific T cells prevent the effects of costimulatory blockade on prolonged cardiac allograft survival in mice. Am J Transplant 2002;2:501-9.
13. Dai Z, Konieczny BT, Lakkis FG. The dual role of IL-2 in the generation and maintenance of CD8+ memory T cells. J Immunol 2000;165:3031-6.
14. Graca L, Thompson S, Lin CY, Adams E, Cobbold SP, Waldmann H. Both CD4(+) CD25(+) and CD4(+)CD25(-) regulatory cells mediate dominant transplantation tolerance. J Immunol 2002;168:5558-65.
15. Kang HG, Zhang D, Degauque N, Mariat C, Alexopoulos S, Zheng XX. Effects of cyclosporine on transplant tolerance: the role of IL-2. Am J Transplant 2007;7: 1907-16.
16. van de Berg PJ, Hoevenaars EC, Yong SL, van Donselaar-van der Pant KA, van Tellingen A, Florquin S, et al. Circulating lymphocyte subsets in different clinical situations after renal transplantation. Immunology 2012;136:198-207.
17. Duvall MG, Precopio ML, Ambrozak DA, Jaye A, McMichael AJ, Whittle HC, et al. Polyfunctional T cell responses are a hallmark of HIV-2 infection. Eur J Immunol 2008;38:350-63.
18. Caccamo N, Guggino G, Joosten SA, Gelsomino G, Di Carlo P, Titone L, et al. Multifunctional CD4(+) T cells correlate with active Mycobacterium tuberculosis infection. Eur J Immunol 2010;40:2211-20.
19. Darrah PA, Patel DT, De Luca PM, Lindsay RW, Davey DF, Flynn BJ, et al.Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major. Nat Med 2007;13:843-50.
20. Wilkinson KA, Wilkinson RJ. Polyfunctional T cells in human tuberculosis. Eur J Immunol 2010;40:2139-42.
21. Chen M, Li XC. Approaches and challenges in targeting memory T cells in transplant tolerance. Arch Immunol Ther Exp (Warsz) 2007;55:309-14.
22. Appay V, van Lier RA, Sallusto F, Roederer M. Phenotype and function of human T lymphocyte subsets: consensus and issues. Cytometry A 2008;73:975-83.
23. Melenhorst JJ, Scheinberg P, Williams A, Ambrozak DR, Keyvanfar K, Smith M, et al. Alloreactivity across HLA barriers is mediated by both naive and antigen-experienced T cells. Biol Blood Marrow Transplant 2011;17:800-9.
24. Hamann D, Baars PA, Rep MH, Hooibrink B, Kerkhof-Garde SR, Klein MR, et al. Phenotypic and functional separation of memory and effector human CD8+ T cells. J Exp Med 1997;186:1407-18.
25. Christopher R, Parish HSW. Use of the intracellular fluorescent dye CFSE to monitor lymphocytemigration and proliferation. In: Coligan JE, Kruisbeek AM,Margulies DH, Shevach EM, Strober W, editors. Current protocols in immunology. John Wiley & Sons, Inc.; 2001. p. 4.9.1-4.9.10.
26. Brook MO, Wood KJ, Jones ND. The impact of memory T cells on rejection and the induction of tolerance. Transplantation 2006;82:1-9.
27. Wu Z, Bensinger SJ, Zhang J, Chen C, Yuan X, Huang X, et al. Homeostatic proliferation is a barrier to transplantation tolerance. Nat Med 2004;10:87-92.
28. Hazenberg MD, Otto SA, de Pauw ES, Roelofs H, Fibbe WE, Hamann D, et al. T-cell receptor excision circle and T-cell dynamics after allogeneic stem cell transplantation are related to clinical events. Blood 2002;99:3449-53.
29. Bingaman AW, Farber DL. Memory T cells in transplantation: generation, function, and potential role in rejection. Am J Transplant 2004;4:846-52.
30. Golshayan D, Wyss JC, Buckland M, Hernandez-Fuentes M, Lechler RI. Differential role of naive and memory CD4 T-cell subsets in primary alloresponses. Am J Transplant 2010;10:1749-59.
31. Willinger T, Freeman T, Hasegawa H, McMichael AJ, Callan MF.Molecular signatures distinguish human central memory from effector memory CD8 T cell subsets. J Immunol 2005;175:5895-903.
32. Makedonas G, BettsMR. Polyfunctional analysis of human T cell responses: importance in vaccine immunogenicity and natural infection. Springer Semin Immunopathol 2006;28:209-19.
33. Thakur A, Pedersen LE, Jungersen G. Immune markers and correlates of protection for vaccine induced immune responses. Vaccine 2012;30:4907-20.
34. Young JM, Adetifa IM, Ota MO, Sutherland JS. Expanded polyfunctional T cell response to mycobacterial antigens in TB disease and contraction post-treatment. PLoS One 2010;5:e11237.
35. Soares AP, Scriba TJ, Joseph S, Harbacheuski R, Murray RA, Gelderbloem SJ, et al. Bacillus Calmette-Guerin vaccination of human newborns induces T cells with complex cytokine and phenotypic profiles. J Immunol 2008;180:3569-77.
36. Trydzenskaya H, Sattler A, Muller K, Schachtner T, Dang-Heine C, Friedrich P, et al. Novel approach for improved assessment of phenotypic and functional characteristics of BKV-specific T-cell immunity. Transplantation 2011;92:1269-77.
37. Harari A, Petitpierre S, Vallelian F, Pantaleo G. Skewed representation of functionally distinct populations of virus-specific CD4 T cells in HIV-1-infected subjects with progressive disease: changes after antiretroviral therapy. Blood 2004;103:966-72.
38. BloomBR, Flynn J,McDonough K, Kress Y, Chan J. Experimental approaches tomechanisms of protection and pathogenesis in M. tuberculosis infection. Immunobiology 1994;191:526-36.
39. Tsuda K, Yamanaka K, Kitagawa H, Akeda T, Naka M, Niwa K, et al. Calcineurin inhibitors suppress cytokine production from memory T cells and differentiation of naive T cells into cytokine-producing mature T cells. PLoS One 2012;7: e31465.
40. Seder RA,Darrah PA, RoedererM. T-cell quality inmemory and protection: implications for vaccine design. Nat Rev Immunol 2008;8:247-58.