Role of salivary vascular endothelial growth factor (VEGF) in palatal mucosal wound healing

Wound Repair and Regeneration

Volumn 21, Issue 4, 2013, Pages 554-562

  Keswani, Sundeep G ^a,b   Balaji, Swathi ^a   Le, Louis D ^a   Leung, Alice ^a   Parvadia, Jignesh K ^a   Frischer, Jason ^a   Yamano, Seiichi ^d   Taichman, Norton ^c   Crombleholme, Timothy M ^a,b  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d HARVARD SCHOOL OF DENTAL MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EPITHELIZATION; FEMALE; MOUSE; NEOVASCULARIZATION (PATHOLOGY); NONHUMAN; PRIORITY JOURNAL; SUBMANDIBULAR GLAND; SUPPLEMENTATION; TISSUE REPAIR; WOUND CLOSURE; WOUND HEALING IMPAIRMENT;

ANIMALS; FEMALE; MICE; MICE, INBRED C57BL; MOUTH MUCOSA; NEOVASCULARIZATION, PHYSIOLOGIC; PALATE; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; RECOMBINANT FUSION PROTEINS; SALIVA; SUBMANDIBULAR GLAND; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WOUND HEALING;

EID: 84879785954     PISSN: 10671927     EISSN: 1524475X     Source Type: Journal    
DOI: 10.1111/wrr.12065     Document Type: Article

References (41)

1. Angelov N, Moutsopoulos N, Jeong MJ, Nares S, Ashcroft G, Wahl SM,. Aberrant mucosal wound repair in the absence of secretory leukocyte protease inhibitor. Thromb Haemost 2004; 92: 288-297.
2. Szpaderska AM, Zuckerman JD, DiPietro LA,. Differential injury responses in oral mucosal and cutaneous wounds. J Dent Res 2003; 82: 621-626.
3. Mandel ID,. The functions of saliva. J Dent Res 1987; 66 (Spec No): 623-627.
4. Zelles T, Purushotham KR, Macauley SP, Oxford GE, Humphreys-Beher MG,. Saliva and growth factors: the fountain of youth resides in us all. J Dent Res 1995; 74: 1826-1832.
5. Cho MA, Ko JY, Kim YK, Kho HS,. Salivary flow rate and clinical characteristics of patients with xerostomia according to its aetiology. J Oral Rehabil 2010; 37: 185-193.
6. Barka T,. Biologically active polypeptides in submandibular glands. J Histochem Cytochem 1980; 28: 836-859.
7. Szpaderska AM, Walsh CG, Steinberg MJ, DiPietro LA,. Distinct patterns of angiogenesis in oral and skin wounds. J Dent Res 2005; 84: 309-314.
8. Schrementi ME, Ferreira AM, Zender C, DiPietro LA,. Site-specific production of TGF-beta in oral mucosal and cutaneous wounds. Wound Repair Regen 2008; 16: 80-86.
9. Parvadia JK, Keswani SG, Vaikunth S, Maldonado AR, Marwan A, Stehr W, et al. Role of VEGF in small bowel adaptation after resection: the adaptive response is angiogenesis dependent. Am J Physiol Gastrointest Liver Physiol 2007; 293: G591-598.
10. Booth V, Young S, Cruchley A, Taichman NS, Paleolog E,. Vascular endothelial growth factor in human periodontal disease. J Periodontal Res 1998; 33: 491-499.
11. Yamaguchi T, Takahashi T,. Effect of salivarectomy on the growth of gastrointestinal mucosa and urinary secretion of epidermal growth factor in rats. Gastroenterol Jpn 1989; 24: 626-631.
12. Helmrath MA, Shin CE, Fox JW, Erwin CR, Warner BW,. Adaptation after small bowel resection is attenuated by sialoadenectomy: the role for endogenous epidermal growth factor. Surgery 1998; 124: 848-854.
13. Holash J, Davis S, Papadopoulos N, Croll SD, Ho L, Russell M, et al. VEGF-Trap: a VEGF blocker with potent antitumor effects. Proc Natl Acad Sci U S A 2002; 99: 11393-11398.
14. Wang S, Baum BJ, Yamano S, Mankani MH, Sun D, Jonsson M, et al. Adenoviral-mediated gene transfer to mouse salivary glands. J Dent Res 2000; 79: 701-708.
15. Keswani SG, Katz AB, Lim FY, Zoltick P, Radu A, Alaee D, et al. Adenoviral mediated gene transfer of PDGF-B enhances wound healing in type I and type II diabetic wounds. Wound Repair Regen 2004; 12: 497-504.
16. Brzozowski T, Konturek SJ, Pytko-Polonczyk J, Warzecha Z,. Gastric adaptation to stress: role of sensory nerves, salivary glands, and adrenal glands. Scand J Gastroenterol 1995; 30: 6-16.
17. Genaro AM, Stranieri GM, Borda E,. Involvement of the endogenous nitric oxide signalling system in bradykinin receptor activation in rat submandibular salivary gland. Arch Oral Biol 2000; 45: 723-729.
18. Buira I, Poch E, Sanchez O, Fernandez-Varo G, Grau M, Tebar F, et al. Sialoadenectomy alters liver cell turn-over and function in mice. J Cell Physiol 2004; 198: 12-21.
19. Jones DE Jr, Tran-Patterson R, Cui DM, Davin D, Estell KP, Miller DM,. Epidermal growth factor secreted from the salivary gland is necessary for liver regeneration. Am J Physiol 1995; 268: G872-878.
20. Warner BB, Ryan AL, Seeger K, Leonard AC, Erwin CR, Warner BW,. Ontogeny of salivary epidermal growth factor and necrotizing enterocolitis. J Pediatr 2007; 150: 358-363.
21. Noguchi S, Ohba Y, Oka T,. Effect of salivary epidermal growth factor on wound healing of tongue in mice. Am J Physiol 1991; 260 (4 Pt 1): E620-625.
22. Chaet MS, Arya G, Ziegler MM, Warner BW,. Epidermal growth factor enhances intestinal adaptation after massive small bowel resection. J Pediatr Surg 1994; 29: 1035-1038; discussion 8-9.
23. Lambotte L, Saliez A, Triest S, Maiter D, Baranski A, Barker A, et al. Effect of sialoadenectomy and epidermal growth factor administration on liver regeneration after partial hepatectomy. Hepatology 1997; 25: 607-612.
24. Brem H, Kodra A, Golinko MS, Entero H, Stojadinovic O, Wang VM, et al. Mechanism of sustained release of vascular endothelial growth factor in accelerating experimental diabetic healing. J Invest Dermatol 2009; 129: 2275-2287.
25. Bao P, Kodra A, Tomic-Canic M, Golinko MS, Ehrlich HP, Brem H,. The role of vascular endothelial growth factor in wound healing. J Surg Res 2009; 153: 347-358.
26. Deng X, Szabo S, Chen L, Paunovic B, Khomenko T, Tolstanova G, et al. New cell therapy using bone marrow-derived stem cells/endothelial progenitor cells to accelerate neovascularization in healing of experimental ulcerative colitis. Curr Pharm Des 2011; 17: 1643-1651.
27. Lee MJ, Kim J, Lee KI, Shin JM, Chae JI, Chung HM,. Enhancement of wound healing by secretory factors of endothelial precursor cells derived from human embryonic stem cells. Cytotherapy 2011; 13: 165-178.
28. Ogunshola OO, Antic A, Donoghue MJ, Fan SY, Kim H, Stewart WB, et al. Paracrine and autocrine functions of neuronal vascular endothelial growth factor (VEGF) in the central nervous system. J Biol Chem 2002; 277: 11410-11415.
29. Taichman NS, Cruchley AT, Fletcher LM, Hagi-Pavli EP, Paleolog EM, Abrams WR, et al. Vascular endothelial growth factor in normal human salivary glands and saliva: a possible role in the maintenance of mucosal homeostasis. Lab Invest 1998; 78: 869-875.
30. Pammer J, Weninger W, Mildner M, Burian M, Wojta J, Tschachler E,. Vascular endothelial growth factor is constitutively expressed in normal human salivary glands and is secreted in the saliva of healthy individuals. J Pathol 1998; 186: 186-191.
31. Brozovic S, Vucicevic-Boras V, Mravak-Stipetic M, Jukic S, Kleinheinz J, Lukac J,. Salivary levels of vascular endothelial growth factor (VEGF) in recurrent aphthous ulceration. J Oral Pathol Med 2002; 31: 106-108.
32. Suzuki N, Takahashi S, Okabe S,. Relationship between vascular endothelial growth factor and angiogenesis in spontaneous and indomethacin-delayed healing of acetic acid-induced gastric ulcers in rats. J Physiol Pharmacol 1998; 49: 515-527.
33. Maharaj AS, D'Amore PA,. Roles for VEGF in the adult. Microvasc Res 2007; 74: 100-113.
34. Werner S, Grose R,. Regulation of wound healing by growth factors and cytokines. Physiol Rev 2003; 83: 835-870.
35. Chernoguz A, Crawford K, Donovan E, Vandersall A, Berglund C, Cripe TP, et al. EGFR inhibition fails to suppress vascular proliferation and tumor growth in a Ewing's sarcoma model. J Surg Res 2012; 173: 1-9.
36. Kemik O, Kemik SA, Purysa S, Tuzun S,. Imbalance of VEGF family serum levels and receptors in patients with inflammatory bowel disease. Bratisl Lek Listy 2010; 111: 439-442.
37. Scaldaferri F, Vetrano S, Sans M, Arena V, Straface G, Stigliano E, et al. VEGF-A links angiogenesis and inflammation in inflammatory bowel disease pathogenesis. Gastroenterology 2009; 136: 585-595 e5.
38. Bodner L, Dayan D, Pinto Y, Hammel I,. Characteristics of palatal wound healing in desalivated rats. Arch Oral Biol 1993; 38: 17-21.
39. Yu L, Liang XH, Ferrara N,. Comparing protein VEGF inhibitors: in vitro biological studies. Biochem Biophys Res Commun 2011; 408: 276-281.
40. Stewart MW,. The expanding role of vascular endothelial growth factor inhibitors in ophthalmology. Mayo Clin Proc 2012; 87: 77-88.
41. Sanchez-Munoz A, Perez-Ruiz E, Mendiola Fernandez C, Alba Conejo E, Gonzalez-Martin A,. Current status of anti-angiogenic agents in the treatment of ovarian carcinoma. Clin Transl Oncol 2009; 11: 589-595.