The efficacy of a glial inhibitor, minocycline, for preventing persistent pain after lumbar discectomy: A randomized, double-blind, controlled study

Pain

Volumn 154, Issue 8, 2013, Pages 1197-1203

  Martinez, Valéria ^a,b   Szekely, Barbara ^c   Lemarié, Jean ^d   Martin, Frederic ^e   Gentili, Marc ^f   Ben Ammar, Skander ^a   Lepeintre, Jean François ^e   Garreau De Loubresse, Christian ^a,g   Chauvin, Marcel ^b,g   Bouhassira, Didier ^b,g   Fletcher, Dominique ^a,b,g  

^a RAYMOND POINCARÉ HOSPITAL   (France)

^b INSERM   (France)

^c FOCH HOSPITAL   (France)

^d Department of Neurosurgery   (France)

^e Hopitaux Privés de Versailles Clinique des Franciscaines   (France)

^f Centre Hospitalier Privé Saint Grégoire Rennes   (France)

^g LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

Author keywords

Controlled study; Double blind; Glial activation; Lumbar discectomy; Minocycline; Persistent pain; Prevention; Randomized

Indexed keywords

MINOCYCLINE; MORPHINE SULFATE; PARACETAMOL; PLACEBO; TRAMADOL;

ADULT; ARTICLE; BACKACHE; BRIEF PAIN INVENTORY; CHRONIC PAIN; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; FUNCTIONAL ASSESSMENT; HUMAN; INTERVERTEBRAL DISKECTOMY; LEG PAIN; LUMBAR DISKECTOMY; MAJOR CLINICAL STUDY; MALE; MORBIDITY; MOVEMENT (PHYSIOLOGY); MULTICENTER STUDY; NEUROPATHIC PAIN; PAIN ASSESSMENT; PATIENT ASSESSMENT; PERIOPERATIVE PERIOD; POSTOPERATIVE ANALGESIA; POSTOPERATIVE PAIN; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; REST; SURGICAL PATIENT; TREATMENT DURATION; TREATMENT OUTCOME;

EID: 84879782710     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1016/j.pain.2013.03.028     Document Type: Article

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