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Volumn 82, Issue 1, 2013, Pages 35-42

Transmission disequilibrium analysis of 31 type 1 diabetes susceptibility loci in Finnish families

Author keywords

Association study; Finnish population; Heterogeneity; Type 1 diabetes

Indexed keywords

INTERLEUKIN 2 RECEPTOR ALPHA; NON RECEPTOR PROTEIN TYROSINE PHOSPHATASE 22;

EID: 84879756961     PISSN: 00012815     EISSN: 13990039     Source Type: Journal    
DOI: 10.1111/tan.12143     Document Type: Article
Times cited : (10)

References (50)
  • 1
    • 67349199566 scopus 로고    scopus 로고
    • Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
    • Barrett JC, Clayton DG, Concannon Pet al. Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes. Nat Genet 2009: 41: 703-7.
    • (2009) Nat Genet , vol.41 , pp. 703-707
    • Barrett, J.C.1    Clayton, D.G.2    Concannon, P.3
  • 2
    • 80053439315 scopus 로고    scopus 로고
    • A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci
    • Bradfield JP, Qu HQ, Wang K et al. A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci. PLoS Genet 2011: 7: e1002293.
    • (2011) PLoS Genet , vol.7
    • Bradfield, J.P.1    Qu, H.Q.2    Wang, K.3
  • 3
    • 70749128610 scopus 로고    scopus 로고
    • Genome-wide association studies in type 1 diabetes, inflammatory bowel disease and other immune-mediated disorders
    • Hakonarson H, Grant SF. Genome-wide association studies in type 1 diabetes, inflammatory bowel disease and other immune-mediated disorders. Semin Immunol 2009: 21: 355-62.
    • (2009) Semin Immunol , vol.21 , pp. 355-362
    • Hakonarson, H.1    Grant, S.F.2
  • 4
    • 77949683112 scopus 로고    scopus 로고
    • The type 1 diabetes-HLA susceptibility interactome-identification of HLA genotype-specific disease genes for type 1 diabetes
    • Brorsson C, Tue Hansen N, Bergholdt R, Brunak S, Pociot F. The type 1 diabetes-HLA susceptibility interactome-identification of HLA genotype-specific disease genes for type 1 diabetes. PLoS One 2010: 5: e9576.
    • (2010) PLoS One , vol.5
    • Brorsson, C.1    Tue Hansen, N.2    Bergholdt, R.3    Brunak, S.4    Pociot, F.5
  • 5
    • 0036319041 scopus 로고    scopus 로고
    • Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes
    • Graham J, Hagopian WA, Kockum I et al. Genetic effects on age-dependent onset and islet cell autoantibody markers in type 1 diabetes. Diabetes 2002: 51: 1346-55.
    • (2002) Diabetes , vol.51 , pp. 1346-1355
    • Graham, J.1    Hagopian, W.A.2    Kockum, I.3
  • 7
    • 0032956643 scopus 로고    scopus 로고
    • Disease-associated autoantibodies and HLA-DQB1 genotypes in children with newly diagnosed insulin-dependent diabetes mellitus (IDDM). The Childhood Diabetes in Finland Study Group
    • Sabbah E, Savola K, Kulmala P et al. Disease-associated autoantibodies and HLA-DQB1 genotypes in children with newly diagnosed insulin-dependent diabetes mellitus (IDDM). The Childhood Diabetes in Finland Study Group. Clin Exp Immunol 1999: 116: 78-83.
    • (1999) Clin Exp Immunol , vol.116 , pp. 78-83
    • Sabbah, E.1    Savola, K.2    Kulmala, P.3
  • 8
    • 0027490736 scopus 로고
    • Insulin autoantibodies and high titre islet cell antibodies are preferentially associated with the HLA DQA1*0301-DQB1*0302 haplotype at clinical type 1 (insulin-dependent) diabetes mellitus before age 10years, but not at onset between age 10 and 40years. The Belgian Diabetes Registry
    • Vandewalle CL, Decraene T, Schuit FC, De Leeuw IH, Pipeleers DG, Gorus FK. Insulin autoantibodies and high titre islet cell antibodies are preferentially associated with the HLA DQA1*0301-DQB1*0302 haplotype at clinical type 1 (insulin-dependent) diabetes mellitus before age 10years, but not at onset between age 10 and 40years. The Belgian Diabetes Registry. Diabetologia 1993: 36: 1155-62.
    • (1993) Diabetologia , vol.36 , pp. 1155-1162
    • Vandewalle, C.L.1    Decraene, T.2    Schuit, F.C.3    De Leeuw, I.H.4    Pipeleers, D.G.5    Gorus, F.K.6
  • 9
    • 0025899032 scopus 로고
    • HLA-associated insulin autoantibody formation in newly diagnosed type I diabetic patients
    • Ziegler AG, Standl E, Albert E, Mehnert H. HLA-associated insulin autoantibody formation in newly diagnosed type I diabetic patients. Diabetes 1991: 40: 1146-9.
    • (1991) Diabetes , vol.40 , pp. 1146-1149
    • Ziegler, A.G.1    Standl, E.2    Albert, E.3    Mehnert, H.4
  • 10
    • 67049159857 scopus 로고    scopus 로고
    • Incidence trends for childhood type 1 diabetes in Europe during 1989-2003 and predicted new cases 2005-20: a multicentre prospective registration study
    • Patterson CC, Dahlquist GG, Gyurus E, Green A, Soltesz G. Incidence trends for childhood type 1 diabetes in Europe during 1989-2003 and predicted new cases 2005-20: a multicentre prospective registration study. Lancet 2009: 373: 2027-33.
    • (2009) Lancet , vol.373 , pp. 2027-2033
    • Patterson, C.C.1    Dahlquist, G.G.2    Gyurus, E.3    Green, A.4    Soltesz, G.5
  • 11
    • 43849096855 scopus 로고    scopus 로고
    • Time trends in the incidence of type 1 diabetes in Finnish children: a cohort study
    • Harjutsalo V, Sjoberg L, Tuomilehto J. Time trends in the incidence of type 1 diabetes in Finnish children: a cohort study. Lancet 2008: 371: 1777-82.
    • (2008) Lancet , vol.371 , pp. 1777-1782
    • Harjutsalo, V.1    Sjoberg, L.2    Tuomilehto, J.3
  • 12
    • 79960735389 scopus 로고    scopus 로고
    • Pathogenesis of type 1 diabetes: implications for incidence trends
    • Knip M. Pathogenesis of type 1 diabetes: implications for incidence trends. Horm Res Paediatr 2011: 76 (Suppl 1): 57-64.
    • (2011) Horm Res Paediatr , vol.76 , Issue.SUPPL 1 , pp. 57-64
    • Knip, M.1
  • 13
    • 9644280863 scopus 로고    scopus 로고
    • Age-dependent influences on the origins of autoimmune diabetes: evidence and implications
    • Leslie RD, Delli CM. Age-dependent influences on the origins of autoimmune diabetes: evidence and implications. Diabetes 2004: 53: 3033-40.
    • (2004) Diabetes , vol.53 , pp. 3033-3040
    • Leslie, R.D.1    Delli, C.M.2
  • 15
    • 0031833918 scopus 로고    scopus 로고
    • A male-female bias in type 1 diabetes and linkage to chromosome Xp in MHC HLA-DR3-positive patients
    • Cucca F, Goy JV, Kawaguchi Y et al. A male-female bias in type 1 diabetes and linkage to chromosome Xp in MHC HLA-DR3-positive patients. Nat Genet 1998: 19: 301-2.
    • (1998) Nat Genet , vol.19 , pp. 301-302
    • Cucca, F.1    Goy, J.V.2    Kawaguchi, Y.3
  • 16
    • 0038222568 scopus 로고    scopus 로고
    • Temporal changes in the frequencies of HLA genotypes in patients with Type 1 diabetes-indication of an increased environmental pressure?
    • Hermann R, Knip M, Veijola R et al. Temporal changes in the frequencies of HLA genotypes in patients with Type 1 diabetes-indication of an increased environmental pressure? Diabetologia 2003: 46: 420-5.
    • (2003) Diabetologia , vol.46 , pp. 420-425
    • Hermann, R.1    Knip, M.2    Veijola, R.3
  • 17
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: a tool set for whole-genome association and population-based linkage analyses
    • Purcell S, Neale B, Todd-Brown K et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 2007: 81: 559-75.
    • (2007) Am J Hum Genet , vol.81 , pp. 559-575
    • Purcell, S.1    Neale, B.2    Todd-Brown, K.3
  • 18
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: a practical and powerful approach to multiple testing
    • Benjamini E, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Series B Stat Methodol 1995: 57: 289-300.
    • (1995) J R Stat Soc Series B Stat Methodol , vol.57 , pp. 289-300
    • Benjamini, E.1    Hochberg, Y.2
  • 19
    • 41649094148 scopus 로고    scopus 로고
    • Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data
    • Dudbridge F. Likelihood-based association analysis for nuclear families and unrelated subjects with missing genotype data. Hum Hered 2008: 66: 87-98.
    • (2008) Hum Hered , vol.66 , pp. 87-98
    • Dudbridge, F.1
  • 20
    • 0345689437 scopus 로고    scopus 로고
    • Candidate gene association analysis for a quantitative trait, using parent-offspring trios
    • Gauderman WJ. Candidate gene association analysis for a quantitative trait, using parent-offspring trios. Genet Epidemiol 2003: 25: 327-38.
    • (2003) Genet Epidemiol , vol.25 , pp. 327-338
    • Gauderman, W.J.1
  • 21
    • 58149091678 scopus 로고    scopus 로고
    • Shared and distinct genetic variants in type 1 diabetes and celiac disease
    • Smyth DJ, Plagnol V, Walker NM et al. Shared and distinct genetic variants in type 1 diabetes and celiac disease. N Engl J Med 2008: 359: 2767-77.
    • (2008) N Engl J Med , vol.359 , pp. 2767-2777
    • Smyth, D.J.1    Plagnol, V.2    Walker, N.M.3
  • 22
    • 34547621758 scopus 로고    scopus 로고
    • A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene
    • Hakonarson H, Grant SF, Bradfield JP et al. A genome-wide association study identifies KIAA0350 as a type 1 diabetes gene. Nature 2007: 448: 591-4.
    • (2007) Nature , vol.448 , pp. 591-594
    • Hakonarson, H.1    Grant, S.F.2    Bradfield, J.P.3
  • 23
    • 34347341846 scopus 로고    scopus 로고
    • Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes
    • Todd JA, Walker NM, Cooper JD et al. Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes. Nat Genet 2007: 39: 857-64.
    • (2007) Nat Genet , vol.39 , pp. 857-864
    • Todd, J.A.1    Walker, N.M.2    Cooper, J.D.3
  • 24
    • 73349115848 scopus 로고    scopus 로고
    • The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes
    • Wallace C, Smyth DJ, Maisuria-Armer M, Walker NM, Todd JA, Clayton DG. The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes. Nat Genet 2010: 42: 68-71.
    • (2010) Nat Genet , vol.42 , pp. 68-71
    • Wallace, C.1    Smyth, D.J.2    Maisuria-Armer, M.3    Walker, N.M.4    Todd, J.A.5    Clayton, D.G.6
  • 25
    • 1642521629 scopus 로고    scopus 로고
    • The human leukocyte antigen genotype has a modest effect on the insulin gene polymorphism-associated susceptibility to type 1 diabetes in the Finnish population
    • Laine AP, Hermann R, Knip M, Simell O, Akerblom HK, Ilonen J. The human leukocyte antigen genotype has a modest effect on the insulin gene polymorphism-associated susceptibility to type 1 diabetes in the Finnish population. Tissue Antigens 2004: 63: 72-4.
    • (2004) Tissue Antigens , vol.63 , pp. 72-74
    • Laine, A.P.1    Hermann, R.2    Knip, M.3    Simell, O.4    Akerblom, H.K.5    Ilonen, J.6
  • 26
    • 9444255760 scopus 로고    scopus 로고
    • Heterogeneity in the magnitude of the insulin gene effect on HLA risk in type 1 diabetes
    • Motzo C, Contu D, Cordell HJ et al. Heterogeneity in the magnitude of the insulin gene effect on HLA risk in type 1 diabetes. Diabetes 2004: 53: 3286-91.
    • (2004) Diabetes , vol.53 , pp. 3286-3291
    • Motzo, C.1    Contu, D.2    Cordell, H.J.3
  • 27
    • 41149154285 scopus 로고    scopus 로고
    • Joint effects of HLA, INS, PTPN22 and CTLA4 genes on the risk of type 1 diabetes
    • Bjornvold M, Undlien DE, Joner G et al. Joint effects of HLA, INS, PTPN22 and CTLA4 genes on the risk of type 1 diabetes. Diabetologia 2008: 51: 589-96.
    • (2008) Diabetologia , vol.51 , pp. 589-596
    • Bjornvold, M.1    Undlien, D.E.2    Joner, G.3
  • 28
    • 80054829515 scopus 로고    scopus 로고
    • Family history of diabetes and distribution of class II HLA genotypes in children with newly diagnosed type 1 diabetes: effect on diabetic ketoacidosis
    • Hekkala A, Ilonen J, Knip M, Veijola R. Family history of diabetes and distribution of class II HLA genotypes in children with newly diagnosed type 1 diabetes: effect on diabetic ketoacidosis. Eur J Endocrinol 2011: 165: 813-7.
    • (2011) Eur J Endocrinol , vol.165 , pp. 813-817
    • Hekkala, A.1    Ilonen, J.2    Knip, M.3    Veijola, R.4
  • 29
    • 75649120798 scopus 로고    scopus 로고
    • Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families
    • Howson JM, Walker NM, Smyth DJ, Todd JA. Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families. Genes Immun 2009: 10 (Suppl 1): S74-84.
    • (2009) Genes Immun , vol.10 , Issue.SUPPL 1
    • Howson, J.M.1    Walker, N.M.2    Smyth, D.J.3    Todd, J.A.4
  • 30
    • 24944506424 scopus 로고    scopus 로고
    • The effect of HLA class II, insulin and CTLA4 gene regions on the development of humoral beta cell autoimmunity
    • Hermann R, Laine AP, Veijola R et al. The effect of HLA class II, insulin and CTLA4 gene regions on the development of humoral beta cell autoimmunity. Diabetologia 2005: 48: 1766-75.
    • (2005) Diabetologia , vol.48 , pp. 1766-1775
    • Hermann, R.1    Laine, A.P.2    Veijola, R.3
  • 31
    • 0033311156 scopus 로고    scopus 로고
    • Diabetes-associated autoantibodies in relation to clinical characteristics and natural course in children with newly diagnosed type 1 diabetes. The Childhood Diabetes In Finland Study Group
    • Sabbah E, Savola K, Kulmala P et al. Diabetes-associated autoantibodies in relation to clinical characteristics and natural course in children with newly diagnosed type 1 diabetes. The Childhood Diabetes In Finland Study Group. J Clin Endocrinol Metab 1999: 84: 1534-9.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 1534-1539
    • Sabbah, E.1    Savola, K.2    Kulmala, P.3
  • 32
    • 0023722804 scopus 로고
    • Concentration of insulin autoantibodies at onset of type I diabetes. Inverse log-linear correlation with age
    • Vardi P, Ziegler AG, Mathews JH et al. Concentration of insulin autoantibodies at onset of type I diabetes. Inverse log-linear correlation with age. Diabetes Care 1988: 11: 736-9.
    • (1988) Diabetes Care , vol.11 , pp. 736-739
    • Vardi, P.1    Ziegler, A.G.2    Mathews, J.H.3
  • 33
    • 33646524724 scopus 로고    scopus 로고
    • Lymphoid tyrosine phosphatase (LYP/PTPN22) Arg620Trp variant regulates insulin autoimmunity and progression to type 1 diabetes
    • Hermann R, Lipponen K, Kiviniemi M et al. Lymphoid tyrosine phosphatase (LYP/PTPN22) Arg620Trp variant regulates insulin autoimmunity and progression to type 1 diabetes. Diabetologia 2006: 49: 1198-208.
    • (2006) Diabetologia , vol.49 , pp. 1198-1208
    • Hermann, R.1    Lipponen, K.2    Kiviniemi, M.3
  • 34
    • 77954887535 scopus 로고    scopus 로고
    • The association between the PTPN22 1858C>T variant and type 1 diabetes depends on HLA risk and GAD65 autoantibodies
    • Maziarz M, Janer M, Roach JC et al. The association between the PTPN22 1858C>T variant and type 1 diabetes depends on HLA risk and GAD65 autoantibodies. Genes Immun 2010: 11: 406-15.
    • (2010) Genes Immun , vol.11 , pp. 406-415
    • Maziarz, M.1    Janer, M.2    Roach, J.C.3
  • 35
    • 48249152671 scopus 로고    scopus 로고
    • PTPN22 Trp620 explains the association of chromosome 1p13 with type 1 diabetes and shows a statistical interaction with HLA class II genotypes
    • Smyth DJ, Cooper JD, Howson JM et al. PTPN22 Trp620 explains the association of chromosome 1p13 with type 1 diabetes and shows a statistical interaction with HLA class II genotypes. Diabetes 2008: 57: 1730-7.
    • (2008) Diabetes , vol.57 , pp. 1730-1737
    • Smyth, D.J.1    Cooper, J.D.2    Howson, J.M.3
  • 36
    • 33750142569 scopus 로고    scopus 로고
    • Association of the PTPN22/LYP gene with type 1 diabetes
    • Steck AK, Liu SY, McFann K et al. Association of the PTPN22/LYP gene with type 1 diabetes. Pediatr Diabetes 2006: 7: 274-8.
    • (2006) Pediatr Diabetes , vol.7 , pp. 274-278
    • Steck, A.K.1    Liu, S.Y.2    McFann, K.3
  • 37
    • 20244373351 scopus 로고    scopus 로고
    • Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms
    • Vella A, Cooper JD, Lowe CE et al. Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms. Am J Hum Genet 2005: 76: 773-9.
    • (2005) Am J Hum Genet , vol.76 , pp. 773-779
    • Vella, A.1    Cooper, J.D.2    Lowe, C.E.3
  • 38
    • 69349102624 scopus 로고    scopus 로고
    • Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource
    • Dendrou CA, Plagnol V, Fung E et al. Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource. Nat Genet 2009: 41: 1011-5.
    • (2009) Nat Genet , vol.41 , pp. 1011-1015
    • Dendrou, C.A.1    Plagnol, V.2    Fung, E.3
  • 39
    • 34548367511 scopus 로고    scopus 로고
    • Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes
    • Lowe CE, Cooper JD, Brusko T et al. Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes. Nat Genet 2007: 39: 1074-82.
    • (2007) Nat Genet , vol.39 , pp. 1074-1082
    • Lowe, C.E.1    Cooper, J.D.2    Brusko, T.3
  • 40
    • 58949100205 scopus 로고    scopus 로고
    • IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production
    • Maier LM, Lowe CE, Cooper J et al. IL2RA genetic heterogeneity in multiple sclerosis and type 1 diabetes susceptibility and soluble interleukin-2 receptor production. PLoS Genet 2009: 5: e1000322.
    • (2009) PLoS Genet , vol.5
    • Maier, L.M.1    Lowe, C.E.2    Cooper, J.3
  • 42
    • 84969213492 scopus 로고    scopus 로고
    • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
    • WTCCC.
    • WTCCC. Genome-wide association study of 14, 000 cases of seven common diseases and 3, 000 shared controls. Nature 2007: 447: 661-78.
    • (2007) Nature , vol.447 , pp. 661-678
  • 43
    • 42449094966 scopus 로고    scopus 로고
    • A novel susceptibility locus for type 1 diabetes on Chr12q13 identified by a genome-wide association study
    • Hakonarson H, Qu HQ, Bradfield JP et al. A novel susceptibility locus for type 1 diabetes on Chr12q13 identified by a genome-wide association study. Diabetes 2008: 57: 1143-6.
    • (2008) Diabetes , vol.57 , pp. 1143-1146
    • Hakonarson, H.1    Qu, H.Q.2    Bradfield, J.P.3
  • 44
    • 80053548022 scopus 로고    scopus 로고
    • FUT2 nonsecretor status links type 1 diabetes susceptibility and resistance to infection
    • Smyth DJ, Cooper JD, Howson JM et al. FUT2 nonsecretor status links type 1 diabetes susceptibility and resistance to infection. Diabetes 2011: 60: 3081-4.
    • (2011) Diabetes , vol.60 , pp. 3081-3084
    • Smyth, D.J.1    Cooper, J.D.2    Howson, J.M.3
  • 45
    • 34948901373 scopus 로고    scopus 로고
    • Association of the vitamin D metabolism gene CYP27B1 with type 1 diabetes
    • Bailey R, Cooper JD, Zeitels L et al. Association of the vitamin D metabolism gene CYP27B1 with type 1 diabetes. Diabetes 2007: 56: 2616-21.
    • (2007) Diabetes , vol.56 , pp. 2616-2621
    • Bailey, R.1    Cooper, J.D.2    Zeitels, L.3
  • 46
    • 61849117976 scopus 로고    scopus 로고
    • Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/TNFAIP3 as a susceptibility locus
    • Fung EY, Smyth DJ, Howson JM et al. Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/TNFAIP3 as a susceptibility locus. Genes Immun 2009: 10: 188-91.
    • (2009) Genes Immun , vol.10 , pp. 188-191
    • Fung, E.Y.1    Smyth, D.J.2    Howson, J.M.3
  • 47
    • 63249115398 scopus 로고    scopus 로고
    • Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes
    • Grant SF, Qu HQ, Bradfield JP et al. Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes. Diabetes 2009: 58: 290-5.
    • (2009) Diabetes , vol.58 , pp. 290-295
    • Grant, S.F.1    Qu, H.Q.2    Bradfield, J.P.3
  • 48
    • 56749183605 scopus 로고    scopus 로고
    • Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci
    • Cooper JD, Smyth DJ, Smiles AM et al. Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci. Nat Genet 2008: 40: 1399-401.
    • (2008) Nat Genet , vol.40 , pp. 1399-1401
    • Cooper, J.D.1    Smyth, D.J.2    Smiles, A.M.3
  • 49
    • 77957126059 scopus 로고    scopus 로고
    • A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk
    • Heinig M, Petretto E, Wallace C et al. A trans-acting locus regulates an anti-viral expression network and type 1 diabetes risk. Nature 2010: 467: 460-4.
    • (2010) Nature , vol.467 , pp. 460-464
    • Heinig, M.1    Petretto, E.2    Wallace, C.3
  • 50
    • 68049144942 scopus 로고    scopus 로고
    • Association of RASGRP1 with type 1 diabetes is revealed by combined follow-up of two genome-wide studies
    • Qu HQ, Grant SF, Bradfield JP et al. Association of RASGRP1 with type 1 diabetes is revealed by combined follow-up of two genome-wide studies. J Med Genet 2009: 46: 553-4.
    • (2009) J Med Genet , vol.46 , pp. 553-554
    • Qu, H.Q.1    Grant, S.F.2    Bradfield, J.P.3


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