Radioprotective efficacy and toxicity of a new family of aminothiol analogs

International Journal of Radiation Biology

Volumn 89, Issue 7, 2013, Pages 485-492

  Copp, Richard R ^a   Peebles, Daniel D ^a   Soref, Cheryl M ^a   Fahl, William E ^a,b  

^a ProCertus BioPharm Inc   (United States)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Amifostine; Cysteine; Glutathione; Radiation dermatitis; ROS scavenger

Indexed keywords

ALIPHATIC AMINE; AMINOTHIOL; CYSTEINE; DISULFIDE; ELECTROPHILE; GLUTATHIONE; POLYAMINE DERIVATIVE; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ARTICLE; CELL GROWTH; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG EFFICACY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; LETHAL DOSE; MAXIMUM TOLERATED DOSE; MOUSE; NONHUMAN; NUCLEOPHILICITY; PRIORITY JOURNAL; RADIATION DERMATITIS; RADIATION DOSE; RADIATION INJURY; RADIATION PROTECTION; SOLUBILITY; WHOLE BODY RADIATION;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; MAXIMUM TOLERATED DOSE; MICE; MICE, INBRED ICR; RADIATION TOLERANCE; RADIATION-PROTECTIVE AGENTS; RADIODERMATITIS; RATS; RATS, SPRAGUE-DAWLEY; SULFHYDRYL COMPOUNDS; SURVIVAL RATE; WHOLE-BODY IRRADIATION;

ANIMALIA; MAMMALIA; MUS;

EID: 84879738877     PISSN: 09553002     EISSN: 13623095     Source Type: Journal    
DOI: 10.3109/09553002.2013.770579     Document Type: Article

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