Synthesis and growth regulatory activity of a prototype member of a new family of aminothiol radioprotectors

Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 24, 2011, Pages 7426-7430

  Copp, Richard R ^b   Peebles, Daniel D ^b   Fahl, William E ^a,b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b ProCertus BioPharm Inc   (United States)

Author keywords

3 (Methylamino) 2 ((methylamino)methyl)propane 1 thiol; Aminothiol; Growth regulator; Polyamine; Radioprotector; ROS scavenger

Indexed keywords

3 (METHYLAMINO) 2 [(METHYLAMINO)METHY])PROPANE 1 THIOL; AMINOTHIOL; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG;

ARTICLE; DRUG ACTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; FIBROBLAST; GROWTH INHIBITION; RADIATION PROTECTION;

AMINES; ANIMALS; CELL LINE; DERMATITIS; DIAMINES; DISEASE MODELS, ANIMAL; HUMANS; POLYAMINES; RADIATION-PROTECTIVE AGENTS; RATS; REACTIVE OXYGEN SPECIES; SULFHYDRYL COMPOUNDS;

EID: 81255199208     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.10.011     Document Type: Article

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